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Items: 31


K-RAS Mutant Gene Found in Pancreatic Juice Activated Chromatin From Peri-ampullary Adenocarcinomas.

Reza J, Almodovar AJ, Srivastava M, Veldhuis PP, Patel S, Fanaian N, Zhu X, Litherland SA, Arnoletti JP.

Epigenet Insights. 2019 Feb 19;12:2516865719828348. doi: 10.1177/2516865719828348. eCollection 2019.


Pancreatic and bile duct cancer circulating tumor cells (CTC) form immune-resistant multi-cell type clusters in the portal venous circulation.

Arnoletti JP, Fanaian N, Reza J, Sause R, Almodovar AJ, Srivastava M, Patel S, Veldhuis PP, Griffith E, Shao YP, Zhu X, Litherland SA.

Cancer Biol Ther. 2018;19(10):887-897. doi: 10.1080/15384047.2018.1480292. Epub 2018 Aug 1.


Blatchford Score Is Superior to AIMS65 Score in Predicting the Need for Clinical Interventions in Elderly Patients with Nonvariceal Upper Gastrointestinal Bleed.

Abusaada K, Asad-Ur-Rahman F, Pech V, Majeed U, Dai S, Zhu X, Litherland SA.

Adv Med. 2016;2016:6850754. doi: 10.1155/2016/6850754. Epub 2016 Aug 28.


Portal Venous Blood Circulation Supports Immunosuppressive Environment and Pancreatic Cancer Circulating Tumor Cell Activation.

Arnoletti JP, Zhu X, Almodovar AJ, Veldhuis PP, Sause R, Griffith E, Corpus G, Chang JC, Fanaian N, Litherland SA.

Pancreas. 2017 Jan;46(1):116-123.


Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6.NODC11bxC1tb Mice.

Garrigan E, Belkin NS, Seydel F, Han Z, Carter J, McDuffie M, Morel L, Peck AB, Clare-Salzler MJ, Atkinson M, Wasserfall C, Davoodi-Semiromi A, Shi JD, Haskell-Luevano C, Yang LJ, Alexander JJ, Cdebaca A, Piliant T, Riggs C, Amick M, Litherland SA.

Genet Epigenet. 2015 Oct 11;7:5-17. doi: 10.4137/GEG.S29696. eCollection 2015.


Ethnicity disparities of breast cancer within an insured population.

Zhu X, Decker V, Almodovar AJ, Litherland SA, Decker DA.

Breast J. 2014 May-Jun;20(3):331-2. doi: 10.1111/tbj.12271. No abstract available.


Persistent STAT5 phosphorylation and epigenetic dysregulation of GM-CSF and PGS2/COX2 expression in Type 1 diabetic human monocytes.

Garrigan E, Belkin NS, Alexander JJ, Han Z, Seydel F, Carter J, Atkinson M, Wasserfall C, Clare-Salzler MJ, Amick MA, Litherland SA.

PLoS One. 2013 Oct 18;8(10):e76919. doi: 10.1371/journal.pone.0076919. eCollection 2013.


In vitro generation of functional insulin-producing cells from human bone marrow-derived stem cells, but long-term culture running risk of malignant transformation.

Tang DQ, Wang Q, Burkhardt BR, Litherland SA, Atkinson MA, Yang LJ.

Am J Stem Cells. 2012 Jun 30;1(2):114-127. Epub 2012 Apr 28.


Developing a nanoparticle test for prostate cancer scoring.

Huo Q, Litherland SA, Sullivan S, Hallquist H, Decker DA, Rivera-Ramirez I.

J Transl Med. 2012 Mar 9;10:44. doi: 10.1186/1479-5876-10-44.


Discovery of a ligand that compensates for decreased endogenous agonist potency of melanocortin-4 receptor polymorphisms identified in obese humans.

Haskell-Luevano C, Xiang Z, Wilczynski AM, Haskell KR, Andreasen AM, Litherland SA, Millard WJ, Pogozheva ID, Mosberg HI, Sorenson NB.

Adv Exp Med Biol. 2009;611:509-10. No abstract available.


Construction and characterization of melanocortin-2 and -4 receptor chimeras.

Wilson KR, Proneth B, Luesch H, Litherland SA, Haskell-Luevano C.

Adv Exp Med Biol. 2009;611:301-2. No abstract available.


M-CSF and GM-CSF regulation of STAT5 activation and DNA binding in myeloid cell differentiation is disrupted in nonobese diabetic mice.

Rumore-Maton B, Elf J, Belkin N, Stutevoss B, Seydel F, Garrigan E, Litherland SA.

Clin Dev Immunol. 2008;2008:769795. doi: 10.1155/2008/769795. Epub 2009 Jan 20.


Immunopathogenic interaction of environmental triggers and genetic susceptibility in diabetes: is epigenetics the missing link?

Litherland SA.

Diabetes. 2008 Dec;57(12):3184-6. doi: 10.2337/db08-1275. No abstract available.


Voluntary exercise prevents the obese and diabetic metabolic syndrome of the melanocortin-4 receptor knockout mouse.

Haskell-Luevano C, Schaub JW, Andreasen A, Haskell KR, Moore MC, Koerper LM, Rouzaud F, Baker HV, Millard WJ, Walter G, Litherland SA, Xiang Z.

FASEB J. 2009 Feb;23(2):642-55. doi: 10.1096/fj.08-109686. Epub 2008 Oct 29.


GM-CSF induces STAT5 binding at epigenetic regulatory sites within the Csf2 promoter of non-obese diabetic (NOD) mouse myeloid cells.

Seydel F, Garrigan E, Stutevoss B, Belkin N, Makadia B, Carter J, Shi JD, Davoodi-Semiromi A, McDuffie M, Litherland SA.

J Autoimmun. 2008 Dec;31(4):377-84. doi: 10.1016/j.jaut.2008.08.010. Epub 2008 Oct 21.


Peptide and small molecules rescue the functional activity and agonist potency of dysfunctional human melanocortin-4 receptor polymorphisms.

Xiang Z, Pogozheva ID, Sorenson NB, Wilczynski AM, Holder JR, Litherland SA, Millard WJ, Mosberg HI, Haskell-Luevano C.

Biochemistry. 2007 Jul 17;46(28):8273-87. Epub 2007 Jun 23.


Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex.

Ostrov DA, Barnes CL, Smith LE, Binns S, Brusko TM, Brown AC, Quint PS, Litherland SA, Roopenian DC, Iczkowski KA.

Tissue Antigens. 2007 Feb;69(2):181-8.


Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis.

Murawski MR, Litherland SA, Clare-Salzler MJ, Davoodi-Semiromi A.

Ann N Y Acad Sci. 2006 Oct;1079:198-204.


Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist.

Xiang Z, Litherland SA, Sorensen NB, Proneth B, Wood MS, Shaw AM, Millard WJ, Haskell-Luevano C.

Biochemistry. 2006 Jun 13;45(23):7277-88.


Molecular mechanism of the constitutive activation of the L250Q human melanocortin-4 receptor polymorphism.

Proneth B, Xiang Z, Pogozheva ID, Litherland SA, Gorbatyuk OS, Shaw AM, Millard WJ, Mosberg HI, Haskell-Luevano C.

Chem Biol Drug Des. 2006 Mar;67(3):215-29.


Signal transduction activator of transcription 5 (STAT5) dysfunction in autoimmune monocytes and macrophages.

Litherland SA, Xie TX, Grebe KM, Davoodi-Semiromi A, Elf J, Belkin NS, Moldawer LL, Clare-Salzler MJ.

J Autoimmun. 2005 Jun;24(4):297-310. Epub 2005 Mar 23.


Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles.

Lian W, Litherland SA, Badrane H, Tan W, Wu D, Baker HV, Gulig PA, Lim DV, Jin S.

Anal Biochem. 2004 Nov 1;334(1):135-44.


In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow.

Tang DQ, Cao LZ, Burkhardt BR, Xia CQ, Litherland SA, Atkinson MA, Yang LJ.

Diabetes. 2004 Jul;53(7):1721-32.


IL10 resistant PGS2 expression in at-risk/Type 1 diabetic human monocytes.

Litherland SA, Xie TX, Grebe KM, Li Y, Moldawer LL, Clare-Salzler MJ.

J Autoimmun. 2004 May;22(3):227-33.


Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset.

Litherland SA, She JX, Schatz D, Fuller K, Hutson AD, Peng RH, Li Y, Grebe KM, Whittaker DS, Bahjat K, Hopkins D, Fang Q, Spies PD, North K, Wasserfall C, Cook R, Dennis MA, Crockett S, Sleasman J, Kocher J, Muir A, Silverstein J, Atkinson M, Clare-Salzler MJ.

Pediatr Diabetes. 2003 Mar;4(1):10-8.


Aberrant prostaglandin synthase 2 expression defines an antigen-presenting cell defect for insulin-dependent diabetes mellitus.

Litherland SA, Xie XT, Hutson AD, Wasserfall C, Whittaker DS, She JX, Hofig A, Dennis MA, Fuller K, Cook R, Schatz D, Moldawer LL, Clare-Salzler MJ.

J Clin Invest. 1999 Aug;104(4):515-23.


Efficacy of the rat bioassay for the determination of biologically available vitamin B-6.

Gregory JF 3rd, Litherland SA.

J Nutr. 1986 Jan;116(1):87-97.


Relative biological activity of nonphosphorylated vitamin B-6 compounds in the rat.

Nguyen LB, Hiner ME, Litherland SA, Gregory JF 3rd.

J Agric Food Chem. 1983 Nov-Dec;31(6):1282-7. No abstract available.


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