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Items: 12


Altered plasmodial surface anion channel activity and in vitro resistance to permeating antimalarial compounds.

Lisk G, Pain M, Sellers M, Gurnev PA, Pillai AD, Bezrukov SM, Desai SA.

Biochim Biophys Acta. 2010 Sep;1798(9):1679-88. doi: 10.1016/j.bbamem.2010.04.013. Epub 2010 May 6.


Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes.

Lisk G, Pain M, Gluzman IY, Kambhampati S, Furuya T, Su XZ, Fay MP, Goldberg DE, Desai SA.

Antimicrob Agents Chemother. 2008 Jul;52(7):2346-54. doi: 10.1128/AAC.00057-08. Epub 2008 Apr 28.


Electrophysiological studies of malaria parasite-infected erythrocytes: current status.

Staines HM, Alkhalil A, Allen RJ, De Jonge HR, Derbyshire E, Egée S, Ginsburg H, Hill DA, Huber SM, Kirk K, Lang F, Lisk G, Oteng E, Pillai AD, Rayavara K, Rouhani S, Saliba KJ, Shen C, Solomon T, Thomas SL, Verloo P, Desai SA.

Int J Parasitol. 2007 Apr;37(5):475-82. Epub 2007 Jan 9. Review.


Solute-inhibitor interactions in the plasmodial surface anion channel reveal complexities in the transport process.

Lisk G, Scott S, Solomon T, Pillai AD, Desai SA.

Mol Pharmacol. 2007 May;71(5):1241-50. Epub 2007 Feb 7.


A blasticidin S-resistant Plasmodium falciparum mutant with a defective plasmodial surface anion channel.

Hill DA, Pillai AD, Nawaz F, Hayton K, Doan L, Lisk G, Desai SA.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):1063-8. Epub 2007 Jan 9.


Specific inhibition of the plasmodial surface anion channel by dantrolene.

Lisk G, Kang M, Cohn JV, Desai SA.

Eukaryot Cell. 2006 Nov;5(11):1882-93. Epub 2006 Sep 1.


Improved perfusion conditions for patch-clamp recordings on human erythrocytes.

Lisk G, Desai SA.

Biochem Biophys Res Commun. 2006 Aug 18;347(1):158-65. Epub 2006 Jun 19.


Malaria parasites are rapidly killed by dantrolene derivatives specific for the plasmodial surface anion channel.

Kang M, Lisk G, Hollingworth S, Baylor SM, Desai SA.

Mol Pharmacol. 2005 Jul;68(1):34-40. Epub 2005 Apr 20.


Evaluation of the therapeutic usefulness of botulinum neurotoxin B, C1, E, and F compared with the long lasting type A. Basis for distinct durations of inhibition of exocytosis in central neurons.

Foran PG, Mohammed N, Lisk GO, Nagwaney S, Lawrence GW, Johnson E, Smith L, Aoki KR, Dolly JO.

J Biol Chem. 2003 Jan 10;278(2):1363-71. Epub 2002 Oct 14.


Recombinant forms of tetanus toxin engineered for examining and exploiting neuronal trafficking pathways.

Li Y, Foran P, Lawrence G, Mohammed N, Chan-Kwo-Chion CK, Lisk G, Aoki R, Dolly O.

J Biol Chem. 2001 Aug 17;276(33):31394-401. Epub 2001 Jun 11.

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