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Items: 43


Pharmacokinetics of Daclatasvir, Sofosbuvir and GS-331007 in a Prospective Cohort of HCV positive Kidney Transplant Recipients.

Schrezenmeier E, Hoffmann F, Jaeger C, Schrezenmeier J, Lisec J, Glander P, Algharably E, Kreutz R, Budde K, Duerr M, Halleck F.

Ther Drug Monit. 2018 Oct 30. doi: 10.1097/FTD.0000000000000567. [Epub ahead of print]


Berberis orthobotrys - A promising herbal anti-tumorigenic candidate for the treatment of pediatric alveolar rhabdomyosarcoma.

Adamus A, Peer K, Ali I, Lisec J, Falodun A, Frank M, Seitz G, Engel N.

J Ethnopharmacol. 2018 Oct 11;229:262-271. doi: 10.1016/j.jep.2018.10.002. [Epub ahead of print]


Nontargeted Identification of Tracer Incorporation in High-Resolution Mass Spectrometry.

Hoffmann F, Jaeger C, Bhattacharya A, Schmitt CA, Lisec J.

Anal Chem. 2018 Jun 19;90(12):7253-7260. doi: 10.1021/acs.analchem.8b00356. Epub 2018 Jun 7.


Statistical and Multivariate Analysis of MS-Based Plant Metabolomics Data.

Jaeger C, Lisec J.

Methods Mol Biol. 2018;1778:285-296. doi: 10.1007/978-1-4939-7819-9_20.


Approaches and techniques to characterize cancer metabolism in vitro and in vivo.

Zaimenko I, Lisec J, Stein U, Brenner W.

Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):412-419. doi: 10.1016/j.bbcan.2017.08.004. Epub 2017 Sep 5. Review.


Age Effects on Hypocotyl Mechanics.

Saxe F, Weichold S, Reinecke A, Lisec J, Döring A, Neumetzler L, Burgert I, Eder M.

PLoS One. 2016 Dec 15;11(12):e0167808. doi: 10.1371/journal.pone.0167808. eCollection 2016.


Automated Annotation and Evaluation of In-Source Mass Spectra in GC/Atmospheric Pressure Chemical Ionization-MS-Based Metabolomics.

Jaeger C, Hoffmann F, Schmitt CA, Lisec J.

Anal Chem. 2016 Oct 4;88(19):9386-9390. Epub 2016 Sep 14.


A naturally occurring promoter polymorphism of the Arabidopsis FUM2 gene causes expression variation, and is associated with metabolic and growth traits.

Riewe D, Jeon HJ, Lisec J, Heuermann MC, Schmeichel J, Seyfarth M, Meyer RC, Willmitzer L, Altmann T.

Plant J. 2016 Dec;88(5):826-838. doi: 10.1111/tpj.13303. Epub 2016 Sep 23.


Extending the Dynamic Range in Metabolomics Experiments by Automatic Correction of Peaks Exceeding the Detection Limit.

Lisec J, Hoffmann F, Schmitt C, Jaeger C.

Anal Chem. 2016 Aug 2;88(15):7487-92. doi: 10.1021/acs.analchem.6b02515. Epub 2016 Jul 21.


Metabolite Profiles of Maize Leaves in Drought, Heat, and Combined Stress Field Trials Reveal the Relationship between Metabolism and Grain Yield.

Obata T, Witt S, Lisec J, Palacios-Rojas N, Florez-Sarasa I, Yousfi S, Araus JL, Cairns JE, Fernie AR.

Plant Physiol. 2015 Dec;169(4):2665-83. doi: 10.1104/pp.15.01164. Epub 2015 Sep 30.


Corrigendum: Gas chromatography mass spectrometry-based metabolite profiling in plants.

Lisec J, Schauer N, Kopka J, Willmitzer L, Fernie AR.

Nat Protoc. 2015 Sep;10(9):1457. doi: 10.1038/nprot0915-1457a. Epub 2015 Aug 27. No abstract available.


Deducing hybrid performance from parental metabolic profiles of young primary roots of maize by using a multivariate diallel approach.

Feher K, Lisec J, Römisch-Margl L, Selbig J, Gierl A, Piepho HP, Nikoloski Z, Willmitzer L.

PLoS One. 2014 Jan 7;9(1):e85435. doi: 10.1371/journal.pone.0085435. eCollection 2014.


Analysis of subcellular metabolite distributions within Arabidopsis thaliana leaf tissue: a primer for subcellular metabolomics.

Krueger S, Steinhauser D, Lisec J, Giavalisco P.

Methods Mol Biol. 2014;1062:575-96. doi: 10.1007/978-1-62703-580-4_30.


Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.

Dörr JR, Yu Y, Milanovic M, Beuster G, Zasada C, Däbritz JH, Lisec J, Lenze D, Gerhardt A, Schleicher K, Kratzat S, Purfürst B, Walenta S, Mueller-Klieser W, Gräler M, Hummel M, Keller U, Buck AK, Dörken B, Willmitzer L, Reimann M, Kempa S, Lee S, Schmitt CA.

Nature. 2013 Sep 19;501(7467):421-5. doi: 10.1038/nature12437. Epub 2013 Aug 14.


Investigating associations between milk metabolite profiles and milk traits of Holstein cows.

Melzer N, Wittenburg D, Hartwig S, Jakubowski S, Kesting U, Willmitzer L, Lisec J, Reinsch N, Repsilber D.

J Dairy Sci. 2013 Mar;96(3):1521-34. doi: 10.3168/jds.2012-5743.


Milk metabolites and their genetic variability.

Wittenburg D, Melzer N, Willmitzer L, Lisec J, Kesting U, Reinsch N, Repsilber D.

J Dairy Sci. 2013 Apr;96(4):2557-2569. doi: 10.3168/jds.2012-5635. Epub 2013 Feb 10.


Metabolic profiling reveals sphingosine-1-phosphate kinase 2 and lyase as key targets of (phyto-) estrogen action in the breast cancer cell line MCF-7 and not in MCF-12A.

Engel N, Lisec J, Piechulla B, Nebe B.

PLoS One. 2012;7(10):e47833. doi: 10.1371/journal.pone.0047833. Epub 2012 Oct 24.


Genome-wide association mapping of leaf metabolic profiles for dissecting complex traits in maize.

Riedelsheimer C, Lisec J, Czedik-Eysenberg A, Sulpice R, Flis A, Grieder C, Altmann T, Stitt M, Willmitzer L, Melchinger AE.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8872-7. doi: 10.1073/pnas.1120813109. Epub 2012 May 21.


A tyrosine aminotransferase involved in tocopherol synthesis in Arabidopsis.

Riewe D, Koohi M, Lisec J, Pfeiffer M, Lippmann R, Schmeichel J, Willmitzer L, Altmann T.

Plant J. 2012 Sep;71(5):850-9. doi: 10.1111/j.1365-313X.2012.05035.x. Epub 2012 Jun 22.


Heterosis manifestation during early Arabidopsis seedling development is characterized by intermediate gene expression and enhanced metabolic activity in the hybrids.

Meyer RC, Witucka-Wall H, Becher M, Blacha A, Boudichevskaia A, Dörmann P, Fiehn O, Friedel S, von Korff M, Lisec J, Melzer M, Repsilber D, Schmidt R, Scholz M, Selbig J, Willmitzer L, Altmann T.

Plant J. 2012 Aug;71(4):669-83. doi: 10.1111/j.1365-313X.2012.05021.x. Epub 2012 Jun 12.


The LysM receptor-like kinase LysM RLK1 is required to activate defense and abiotic-stress responses induced by overexpression of fungal chitinases in Arabidopsis plants.

Brotman Y, Landau U, Pnini S, Lisec J, Balazadeh S, Mueller-Roeber B, Zilberstein A, Willmitzer L, Chet I, Viterbo A.

Mol Plant. 2012 Sep;5(5):1113-24. doi: 10.1093/mp/sss021. Epub 2012 Mar 28.


Matapax: an online high-throughput genome-wide association study pipeline.

Childs LH, Lisec J, Walther D.

Plant Physiol. 2012 Apr;158(4):1534-41. doi: 10.1104/pp.112.194027. Epub 2012 Feb 21.


Genomic and metabolic prediction of complex heterotic traits in hybrid maize.

Riedelsheimer C, Czedik-Eysenberg A, Grieder C, Lisec J, Technow F, Sulpice R, Altmann T, Stitt M, Willmitzer L, Melchinger AE.

Nat Genet. 2012 Jan 15;44(2):217-20. doi: 10.1038/ng.1033.


Metabolic and phenotypic responses of greenhouse-grown maize hybrids to experimentally controlled drought stress.

Witt S, Galicia L, Lisec J, Cairns J, Tiessen A, Araus JL, Palacios-Rojas N, Fernie AR.

Mol Plant. 2012 Mar;5(2):401-17. doi: 10.1093/mp/ssr102. Epub 2011 Dec 15.


Transcript and metabolite analysis of the Trichoderma-induced systemic resistance response to Pseudomonas syringae in Arabidopsis thaliana.

Brotman Y, Lisec J, Méret M, Chet I, Willmitzer L, Viterbo A.

Microbiology. 2012 Jan;158(Pt 1):139-46. doi: 10.1099/mic.0.052621-0. Epub 2011 Aug 18.


Corn hybrids display lower metabolite variability and complex metabolite inheritance patterns.

Lisec J, Römisch-Margl L, Nikoloski Z, Piepho HP, Giavalisco P, Selbig J, Gierl A, Willmitzer L.

Plant J. 2011 Oct;68(2):326-36. doi: 10.1111/j.1365-313X.2011.04689.x. Epub 2011 Jul 27.


Identification of enzymatic and regulatory genes of plant metabolism through QTL analysis in Arabidopsis.

Brotman Y, Riewe D, Lisec J, Meyer RC, Willmitzer L, Altmann T.

J Plant Physiol. 2011 Aug 15;168(12):1387-94. doi: 10.1016/j.jplph.2011.03.008. Epub 2011 May 4.


Coccolithophorid algae culture in closed photobioreactors.

Moheimani NR, Isdepsky A, Lisec J, Raes E, Borowitzka MA.

Biotechnol Bioeng. 2011 Sep;108(9):2078-87. doi: 10.1002/bit.23161. Epub 2011 Apr 25.


Bacterial cultures preferentially removing singly flanked chlorine substituents from chlorobenzenes.

Hölscher T, Lisec J, Baani M, Duan TH, Adrian L.

Environ Sci Technol. 2010 Dec 1;44(23):8936-42. doi: 10.1021/es101971m. Epub 2010 Nov 2.


Probing the reproducibility of leaf growth and molecular phenotypes: a comparison of three Arabidopsis accessions cultivated in ten laboratories.

Massonnet C, Vile D, Fabre J, Hannah MA, Caldana C, Lisec J, Beemster GT, Meyer RC, Messerli G, Gronlund JT, Perkovic J, Wigmore E, May S, Bevan MW, Meyer C, Rubio-Díaz S, Weigel D, Micol JL, Buchanan-Wollaston V, Fiorani F, Walsh S, Rinn B, Gruissem W, Hilson P, Hennig L, Willmitzer L, Granier C.

Plant Physiol. 2010 Apr;152(4):2142-57. doi: 10.1104/pp.109.148338. Epub 2010 Mar 3.


TargetSearch--a Bioconductor package for the efficient preprocessing of GC-MS metabolite profiling data.

Cuadros-Inostroza A, Caldana C, Redestig H, Kusano M, Lisec J, Peña-Cortés H, Willmitzer L, Hannah MA.

BMC Bioinformatics. 2009 Dec 16;10:428. doi: 10.1186/1471-2105-10-428.


Prediction of hybrid biomass in Arabidopsis thaliana by selected parental SNP and metabolic markers.

Steinfath M, Gärtner T, Lisec J, Meyer RC, Altmann T, Willmitzer L, Selbig J.

Theor Appl Genet. 2010 Jan;120(2):239-47. doi: 10.1007/s00122-009-1191-2. Epub 2009 Nov 13.


QTL analysis of early stage heterosis for biomass in Arabidopsis.

Meyer RC, Kusterer B, Lisec J, Steinfath M, Becher M, Scharr H, Melchinger AE, Selbig J, Schurr U, Willmitzer L, Altmann T.

Theor Appl Genet. 2010 Jan;120(2):227-37. doi: 10.1007/s00122-009-1074-6.


Identification of heterotic metabolite QTL in Arabidopsis thaliana RIL and IL populations.

Lisec J, Steinfath M, Meyer RC, Selbig J, Melchinger AE, Willmitzer L, Altmann T.

Plant J. 2009 Sep;59(5):777-88. doi: 10.1111/j.1365-313X.2009.03910.x. Epub 2009 May 4.


Improved heterosis prediction by combining information on DNA- and metabolic markers.

Gärtner T, Steinfath M, Andorf S, Lisec J, Meyer RC, Altmann T, Willmitzer L, Selbig J.

PLoS One. 2009;4(4):e5220. doi: 10.1371/journal.pone.0005220. Epub 2009 Apr 16.


High-resolution direct infusion-based mass spectrometry in combination with whole 13C metabolome isotope labeling allows unambiguous assignment of chemical sum formulas.

Giavalisco P, Hummel J, Lisec J, Inostroza AC, Catchpole G, Willmitzer L.

Anal Chem. 2008 Dec 15;80(24):9417-25. doi: 10.1021/ac8014627.


Mild reductions in mitochondrial citrate synthase activity result in a compromised nitrate assimilation and reduced leaf pigmentation but have no effect on photosynthetic performance or growth.

Sienkiewicz-Porzucek A, Nunes-Nesi A, Sulpice R, Lisec J, Centeno DC, Carillo P, Leisse A, Urbanczyk-Wochniak E, Fernie AR.

Plant Physiol. 2008 May;147(1):115-27. doi: 10.1104/pp.108.117978. Epub 2008 Mar 21.


Metabolite profile analysis: from raw data to regression and classification.

Steinfath M, Groth D, Lisec J, Selbig J.

Physiol Plant. 2008 Feb;132(2):150-61. doi: 10.1111/j.1399-3054.2007.01006.x. Review.


Identification of metabolic and biomass QTL in Arabidopsis thaliana in a parallel analysis of RIL and IL populations.

Lisec J, Meyer RC, Steinfath M, Redestig H, Becher M, Witucka-Wall H, Fiehn O, Törjék O, Selbig J, Altmann T, Willmitzer L.

Plant J. 2008 Mar;53(6):960-72. Epub 2007 Nov 28.


GC-EI-TOF-MS analysis of in vivo carbon-partitioning into soluble metabolite pools of higher plants by monitoring isotope dilution after 13CO2 labelling.

Huege J, Sulpice R, Gibon Y, Lisec J, Koehl K, Kopka J.

Phytochemistry. 2007 Aug-Sep;68(16-18):2258-72. Epub 2007 May 1.


Gas chromatography mass spectrometry-based metabolite profiling in plants.

Lisec J, Schauer N, Kopka J, Willmitzer L, Fernie AR.

Nat Protoc. 2006;1(1):387-96. Erratum in: Nat Protoc. 2015 Sep;10(9):1457.


The metabolic signature related to high plant growth rate in Arabidopsis thaliana.

Meyer RC, Steinfath M, Lisec J, Becher M, Witucka-Wall H, Törjék O, Fiehn O, Eckardt A, Willmitzer L, Selbig J, Altmann T.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4759-64. Epub 2007 Mar 5.

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