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Items: 33

1.

Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets.

Kapsalis C, Wang B, El Mkami H, Pitt SJ, Schnell JR, Smith TK, Lippiat JD, Bode BE, Pliotas C.

Nat Commun. 2019 Oct 10;10(1):4619. doi: 10.1038/s41467-019-12591-x.

2.

A cytoplasmic Slo3 isoform is expressed in somatic tissues.

Chávez JC, Vicens A, Wrighton DC, Andrade-López K, Beltrán C, Gutiérrez RM, Lippiat JD, Treviño CL.

Mol Biol Rep. 2019 Oct;46(5):5561-5567. doi: 10.1007/s11033-019-04943-z. Epub 2019 Jul 3.

PMID:
31270758
3.

Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids.

Gauer JS, Tumova S, Lippiat JD, Kerimi A, Williamson G.

Biochem Pharmacol. 2018 Jun;152:11-20. doi: 10.1016/j.bcp.2018.03.011. Epub 2018 Mar 14.

4.

The cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motility.

Stakaitytė G, Nwogu N, Lippiat JD, Blair GE, Poterlowicz K, Boyne JR, Macdonald A, Mankouri J, Whitehouse A.

J Biol Chem. 2018 Mar 23;293(12):4582-4590. doi: 10.1074/jbc.RA117.001343. Epub 2018 Feb 8.

5.

Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5.

Al-Owais MM, Hettiarachchi NT, Boyle JP, Scragg JL, Elies J, Dallas ML, Lippiat JD, Steele DS, Peers C.

Cell Death Dis. 2017 Nov 2;8(11):e3163. doi: 10.1038/cddis.2017.568.

6.

Affimer proteins are versatile and renewable affinity reagents.

Tiede C, Bedford R, Heseltine SJ, Smith G, Wijetunga I, Ross R, AlQallaf D, Roberts AP, Balls A, Curd A, Hughes RE, Martin H, Needham SR, Zanetti-Domingues LC, Sadigh Y, Peacock TP, Tang AA, Gibson N, Kyle H, Platt GW, Ingram N, Taylor T, Coletta LP, Manfield I, Knowles M, Bell S, Esteves F, Maqbool A, Prasad RK, Drinkhill M, Bon RS, Patel V, Goodchild SA, Martin-Fernandez M, Owens RJ, Nettleship JE, Webb ME, Harrison M, Lippiat JD, Ponnambalam S, Peckham M, Smith A, Ferrigno PK, Johnson M, McPherson MJ, Tomlinson DC.

Elife. 2017 Jun 27;6. pii: e24903. doi: 10.7554/eLife.24903.

7.

The changing landscape of membrane protein structural biology through developments in electron microscopy.

Rawson S, Davies S, Lippiat JD, Muench SP.

Mol Membr Biol. 2016 Mar;33(1-2):12-22. Epub 2016 Sep 9. Review.

8.

Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium.

Wrighton DC, Muench SP, Lippiat JD.

Br J Pharmacol. 2015 Sep;172(17):4355-63. doi: 10.1111/bph.13214. Epub 2015 Jul 14.

9.

Requirement for chloride channel function during the hepatitis C virus life cycle.

Igloi Z, Mohl BP, Lippiat JD, Harris M, Mankouri J.

J Virol. 2015 Apr;89(7):4023-9. doi: 10.1128/JVI.02946-14. Epub 2015 Jan 21.

10.

Activation of the Cl- channel ANO1 by localized calcium signals in nociceptive sensory neurons requires coupling with the IP3 receptor.

Jin X, Shah S, Liu Y, Zhang H, Lees M, Fu Z, Lippiat JD, Beech DJ, Sivaprasadarao A, Baldwin SA, Zhang H, Gamper N.

Sci Signal. 2013 Aug 27;6(290):ra73. doi: 10.1126/scisignal.2004184.

11.

Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients.

Gorvin CM, Wilmer MJ, Piret SE, Harding B, van den Heuvel LP, Wrong O, Jat PS, Lippiat JD, Levtchenko EN, Thakker RV.

Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):7014-9. doi: 10.1073/pnas.1302063110. Epub 2013 Apr 9.

12.

Conventional micropipette-based patch clamp techniques.

Lippiat JD, Wrighton DC.

Methods Mol Biol. 2013;998:91-107. doi: 10.1007/978-1-62703-351-0_7.

PMID:
23529423
13.

The CLC-5 2Cl(-)/H(+) exchange transporter in endosomal function and Dent's disease.

Lippiat JD, Smith AJ.

Front Physiol. 2012 Nov 30;3:449. doi: 10.3389/fphys.2012.00449. eCollection 2012.

14.

Constitutively active TRPC channels of adipocytes confer a mechanism for sensing dietary fatty acids and regulating adiponectin.

Sukumar P, Sedo A, Li J, Wilson LA, O'Regan D, Lippiat JD, Porter KE, Kearney MT, Ainscough JF, Beech DJ.

Circ Res. 2012 Jul 6;111(2):191-200. doi: 10.1161/CIRCRESAHA.112.270751. Epub 2012 Jun 5.

15.

Carrier-mediated transport of quercetin conjugates: involvement of organic anion transporters and organic anion transporting polypeptides.

Wong CC, Akiyama Y, Abe T, Lippiat JD, Orfila C, Williamson G.

Biochem Pharmacol. 2012 Aug 15;84(4):564-70. doi: 10.1016/j.bcp.2012.05.011. Epub 2012 May 23.

PMID:
22634047
16.

Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger.

Smith AJ, Lippiat JD.

FASEB J. 2010 Oct;24(10):3696-705. doi: 10.1096/fj.09-150649. Epub 2010 May 25.

17.

Direct endosomal acidification by the outwardly rectifying CLC-5 Cl(-)/H(+) exchanger.

Smith AJ, Lippiat JD.

J Physiol. 2010 Jun 15;588(Pt 12):2033-45. doi: 10.1113/jphysiol.2010.188540. Epub 2010 Apr 26.

18.

Constitutive endocytic recycling and protein kinase C-mediated lysosomal degradation control K(ATP) channel surface density.

Manna PT, Smith AJ, Taneja TK, Howell GJ, Lippiat JD, Sivaprasadarao A.

J Biol Chem. 2010 Feb 19;285(8):5963-73. doi: 10.1074/jbc.M109.066902. Epub 2009 Dec 21.

19.

CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease.

Reed AA, Loh NY, Terryn S, Lippiat JD, Partridge C, Galvanovskis J, Williams SE, Jouret F, Wu FT, Courtoy PJ, Nesbit MA, Rorsman P, Devuyst O, Ashcroft FM, Thakker RV.

Am J Physiol Renal Physiol. 2010 Feb;298(2):F365-80. doi: 10.1152/ajprenal.00038.2009. Epub 2009 Nov 25.

20.

Mutational analysis of CLC-5, cofilin and CLC-4 in patients with Dent's disease.

Wu F, Reed AA, Williams SE, Loh NY, Lippiat JD, Christie PT, Large O, Bettinelli A, Dillon MJ, Goldraich NP, Hoppe B, Lhotta K, Loirat C, Malik R, Morel D, Kotanko P, Roussel B, Rubinger D, Schrander-Stumpel C, Serdaroglu E, Nesbit MA, Ashcroft F, Thakker RV.

Nephron Physiol. 2009;112(4):p53-62. doi: 10.1159/000225944. Epub 2009 Jun 20.

PMID:
19546591
21.

Characterization of Dent's disease mutations of CLC-5 reveals a correlation between functional and cell biological consequences and protein structure.

Smith AJ, Reed AA, Loh NY, Thakker RV, Lippiat JD.

Am J Physiol Renal Physiol. 2009 Feb;296(2):F390-7. doi: 10.1152/ajprenal.90526.2008. Epub 2008 Nov 19.

22.

Analysing steroid modulation of BK(Ca) channels reconstituted into planar lipid bilayers.

de Wet H, Lippiat JD, Allen M.

Methods Mol Biol. 2008;491:177-86. doi: 10.1007/978-1-59745-526-8_14.

PMID:
18998093
23.

Whole-cell recording using the perforated patch clamp technique.

Lippiat JD.

Methods Mol Biol. 2008;491:141-9. doi: 10.1007/978-1-59745-526-8_11.

PMID:
18998090
24.

Modulation of the BK channel by estrogens: examination at single channel level.

De Wet H, Allen M, Holmes C, Stobbart M, Lippiat JD, Callaghan R.

Mol Membr Biol. 2006 Sep-Oct;23(5):420-9.

PMID:
17060159
25.

Mutations at the same residue (R50) of Kir6.2 (KCNJ11) that cause neonatal diabetes produce different functional effects.

Shimomura K, Girard CA, Proks P, Nazim J, Lippiat JD, Cerutti F, Lorini R, Ellard S, Hattersley AT, Barbetti F, Ashcroft FM.

Diabetes. 2006 Jun;55(6):1705-12. Erratum in: Diabetes. 2007 Mar;56(3):897. Hattersely, Andrew T [corrected to Hattersley, Andrew T].

26.

Membrane ion channels and diabetes.

Proks P, Lippiat JD.

Curr Pharm Des. 2006;12(4):485-501. Review.

PMID:
16472141
27.

A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.

Toye AA, Lippiat JD, Proks P, Shimomura K, Bentley L, Hugill A, Mijat V, Goldsworthy M, Moir L, Haynes A, Quarterman J, Freeman HC, Ashcroft FM, Cox RD.

Diabetologia. 2005 Apr;48(4):675-86. Epub 2005 Feb 24.

PMID:
15729571
28.
29.

ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer.

Tsuboi T, Lippiat JD, Ashcroft FM, Rutter GA.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):76-81. Epub 2003 Dec 17.

30.

Properties of BK(Ca) channels formed by bicistronic expression of hSloalpha and beta1-4 subunits in HEK293 cells.

Lippiat JD, Standen NB, Harrow ID, Phillips SC, Davies NW.

J Membr Biol. 2003 Mar 15;192(2):141-8.

PMID:
12682801
31.
32.
33.

Block of cloned BKCa channels (rSlo) expressed in HEK 293 cells by N-methyl d-glucamine.

Lippiat JD, Standen NB, Davies NW.

Pflugers Arch. 1998 Oct;436(5):810-2.

PMID:
9716719

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