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The MAP2K4/JNK/c-Jun Signaling Pathway Plays A Key Role In Dexmedetomidine Protection Against Acetaminophen-Induced Liver Toxicity.

Chou AH, Liao CC, Lee HC, Liou JT, Liu FC.

Drug Des Devel Ther. 2019 Nov 14;13:3887-3898. doi: 10.2147/DDDT.S215473. eCollection 2019.


Correction to Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α.

Barylko B, Chen YJ, Hennen J, Angert I, Chen Y, Mueller JD, Sun HQ, Taylor CA 4th, Liou J, Yin H, Albanesi JP.

Biochemistry. 2019 Dec 4. doi: 10.1021/acs.biochem.9b00904. [Epub ahead of print] No abstract available.


Spectroscopic and Electrical Characterizations of Low-Damage Phosphorous-Doped Graphene via Ion Implantation.

He SM, Huang CC, Liou JW, Woon WY, Su CY.

ACS Appl Mater Interfaces. 2019 Dec 4. doi: 10.1021/acsami.9b18479. [Epub ahead of print]


Ex vivo multi-electrode analysis reveals spatiotemporal dynamics of ictal behavior at the infiltrated margin of glioma.

Gill BJA, Wu X, Khan FA, Sosunov AA, Liou JY, Dovas A, Eissa TL, Banu MA, Bateman LM, McKhann GM 2nd, Canoll P, Schevon C.

Neurobiol Dis. 2019 Nov 12;134:104676. doi: 10.1016/j.nbd.2019.104676. [Epub ahead of print]


A multicenter prospective study of first-line antibiotic therapy for early-stage gastric mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma with histological evidence of mucosa-associated lymphoid tissue.

Tsai HJ, Tai JJ, Chen LT, Wu MS, Yeh KH, Lin CW, Wang TE, Wang HP, Yu FJ, Liou JM, Hsiao CF, Cheng TY, Yeh HJ, Ko CW, Chen MJ, Lo GH, Hsu PI, Chang CS, Hwang WS, Chuang SS, Lee HW, Shun CT, Chiu CF, Wang WM, Hsieh CY, Liu TW, Lin JT, Kuo SH, Cheng AL.

Haematologica. 2019 Nov 14. pii: haematol.2019.228775. doi: 10.3324/haematol.2019.228775. [Epub ahead of print] No abstract available.


Acute myocarditis complicated with permanent complete atrioventricular block caused by Escherichia coli bacteremia: A rare case report.

Hsu CT, Hsiao PJ, Liu CH, Chou YL, Chen BH, Liou JT.

Medicine (Baltimore). 2019 Nov;98(44):e17833. doi: 10.1097/MD.0000000000017833.


Direct Synthesis of Large-Scale Multilayer TaSe2 on SiO2/Si Using Ion Beam Technology.

Tsai HS, Liu FW, Liou JW, Chi CC, Tang SY, Wang C, Ouyang H, Chueh YL, Liu C, Zhou S, Woon WY.

ACS Omega. 2019 Oct 8;4(17):17536-17541. doi: 10.1021/acsomega.9b02441. eCollection 2019 Oct 22.


N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression.

Mehndiratta S, Lin MH, Wu YW, Chen CH, Wu TY, Chuang KH, Chao MW, Chen YY, Pan SL, Chen MC, Liou JP.

Eur J Med Chem. 2020 Jan 1;185:111725. doi: 10.1016/j.ejmech.2019.111725. Epub 2019 Sep 24.


MPT0G612, a Novel HDAC6 Inhibitor, Induces Apoptosis and Suppresses IFN-γ-Induced Programmed Death-Ligand 1 in Human Colorectal Carcinoma Cells.

Chen MC, Lin YC, Liao YH, Liou JP, Chen CH.

Cancers (Basel). 2019 Oct 22;11(10). pii: E1617. doi: 10.3390/cancers11101617.


TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis.

Huang HL, Liu YM, Sung TY, Huang TC, Cheng YW, Liou JP, Pan SL.

Theranostics. 2019 Sep 18;9(22):6676-6689. doi: 10.7150/thno.34020. eCollection 2019.


Characterization of Bifidobacterium species in feaces of the Egyptian fruit bat: Description of B. vespertilionis sp. nov. and B. rousetti sp. nov.

Modesto M, Satti M, Watanabe K, Puglisi E, Morelli L, Huang CH, Liou JS, Miyashita M, Tamura T, Saito S, Mori K, Huang L, Sciavilla P, Sandri C, Spiezio C, Vitali F, Cavalieri D, Perpetuini G, Tofalo R, Bonetti A, Arita M, Mattarelli P.

Syst Appl Microbiol. 2019 Nov;42(6):126017. doi: 10.1016/j.syapm.2019.126017. Epub 2019 Sep 23.


The association of ischaemic stroke in patients with heart failure without atrial flutter/fibrillation.

Chou YL, Liou JT, Cheng CC, Tsai MC, Lin WS, Cheng SM, Lin CL, Lin CS, Kao CH.

Heart. 2019 Oct 3. pii: heartjnl-2019-315646. doi: 10.1136/heartjnl-2019-315646. [Epub ahead of print]


Long-term changes of gut microbiota, antibiotic resistance, and metabolic parameters after Helicobacter pylori eradication: a multicentre, open-label, randomised trial.

Liou JM, Chen CC, Chang CM, Fang YJ, Bair MJ, Chen PY, Chang CY, Hsu YC, Chen MJ, Chen CC, Lee JY, Yang TH, Luo JC, Chen CY, Hsu WF, Chen YN, Wu JY, Lin JT, Lu TP, Chuang EY, El-Omar EM, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

Lancet Infect Dis. 2019 Oct;19(10):1109-1120. doi: 10.1016/S1473-3099(19)30272-5.


Green synthesis of gold nanoparticle/gelatin/protein nanogels with enhanced bioluminescence/biofluorescence.

Chen IH, Chen YF, Liou JH, Lai JT, Hsu CC, Wang NY, Jan JS.

Mater Sci Eng C Mater Biol Appl. 2019 Dec;105:110101. doi: 10.1016/j.msec.2019.110101. Epub 2019 Aug 19.


Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.

Li J, Shang G, Chen YJ, Brautigam CA, Liou J, Zhang X, Bai XC.

Elife. 2019 Sep 19;8. pii: e47650. doi: 10.7554/eLife.47650.


Targeting Autophagy by MPT0L145, a Highly Potent PIK3C3 Inhibitor, Provides Synergistic Interaction to Targeted or Chemotherapeutic Agents in Cancer Cells.

Chen CH, Hsieh TH, Lin YC, Liu YR, Liou JP, Yen Y.

Cancers (Basel). 2019 Sep 11;11(9). pii: E1345. doi: 10.3390/cancers11091345.


Localization of cells using magnetized patterned thin films.

Huang HT, Wei ZH, Liou JJ, Zhao WD, Xu XZ.

Mater Sci Eng C Mater Biol Appl. 2019 Nov;104:109875. doi: 10.1016/j.msec.2019.109875. Epub 2019 Jun 8.


Review: Treatment of Helicobacter pylori Infection 2019.

O'Connor A, Liou JM, Gisbert JP, O'Morain C.

Helicobacter. 2019 Sep;24 Suppl 1:e12640. doi: 10.1111/hel.12640.


Reclassification of Micrococcus aloeverae and Micrococcus yunnanensis as later heterotypic synonyms of Micrococcus luteus.

Huang CH, Wang CL, Liou JS, Lee AY, Blom J, Huang L, Watanabe K.

Int J Syst Evol Microbiol. 2019 Nov;69(11):3512-3518. doi: 10.1099/ijsem.0.003654.


Investigation of quality review issues and the association with application characteristics for new drug applications in first-cycle reviews.

Liou JS, Chang LC.

Regul Toxicol Pharmacol. 2019 Nov;108:104448. doi: 10.1016/j.yrtph.2019.104448. Epub 2019 Aug 22.


Burst suppression uncovers rapid widespread alterations in network excitability caused by an acute seizure focus.

Liou JY, Baird-Daniel E, Zhao M, Daniel A, Schevon CA, Ma H, Schwartz TH.

Brain. 2019 Oct 1;142(10):3045-3058. doi: 10.1093/brain/awz246.


Application of Helicobacter pylori stool antigen test to survey the updated prevalence of H. pylori infection in Taiwan.

Chen MJ, Fang YJ, Wu MS, Chen CC, Chen YN, Yu CC, Kuo CC, Chiu MC, Hu WH, Tsai MH, Hsieh CL, Chen HH, Bair MJ, Liou JM; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

J Gastroenterol Hepatol. 2019 Aug 13. doi: 10.1111/jgh.14828. [Epub ahead of print]


Draft Genome Sequence of Mediterraneibacter sp. nov. Strain gm002, Isolated from Human Feces.

Huang CH, Liou JS, Wang CL, Huang L.

Microbiol Resour Announc. 2019 Aug 1;8(31). pii: e00217-19. doi: 10.1128/MRA.00217-19.


Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells.

Nepali K, Lin MH, Chao MW, Peng SJ, Hsu KC, Eight Lin T, Chen MC, Lai MJ, Pan SL, Liou JP.

Bioorg Chem. 2019 Oct;91:103119. doi: 10.1016/j.bioorg.2019.103119. Epub 2019 Jul 15.


Pitavastatin Exerts Potent Anti-Inflammatory and Immunomodulatory Effects via the Suppression of AP-1 Signal Transduction in Human T Cells.

Chen LW, Lin CS, Tsai MC, Shih SF, Lim ZW, Chen SJ, Tsui PF, Ho LJ, Lai JH, Liou JT.

Int J Mol Sci. 2019 Jul 19;20(14). pii: E3534. doi: 10.3390/ijms20143534.


Risk of adverse cardiovascular events with use of inhaled long-acting bronchodilators in management of chronic obstructive pulmonary disease.

Wang MT, Lai JH, Tsai CL, Liou JT.

J Food Drug Anal. 2019 Jul;27(3):657-670. doi: 10.1016/j.jfda.2018.12.006. Epub 2019 Jan 7. Review.


Engineering Forward Genetics into Cultured Cancer Cells for Chemical Target Identification.

Povedano JM, Liou J, Wei D, Srivatsav A, Kim J, Xie Y, Nijhawan D, McFadden DG.

Cell Chem Biol. 2019 Sep 19;26(9):1315-1321.e3. doi: 10.1016/j.chembiol.2019.06.006. Epub 2019 Jul 11.


Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson's disease.

Lin CH, Chen CC, Chiang HL, Liou JM, Chang CM, Lu TP, Chuang EY, Tai YC, Cheng C, Lin HY, Wu MS.

J Neuroinflammation. 2019 Jun 27;16(1):129. doi: 10.1186/s12974-019-1528-y.


Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α.

Barylko B, Chen YJ, Hennen J, Angert I, Chen Y, Mueller JD, Sun HQ, Taylor CA 4th, Liou J, Yin H, Albanesi JP.

Biochemistry. 2019 Jun 25;58(25):2809-2813. doi: 10.1021/acs.biochem.9b00299. Epub 2019 Jun 11. Erratum in: Biochemistry. 2019 Dec 4;:.


Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status.

Chao MW, Chang LH, Tu HJ, Chang CD, Lai MJ, Chen YY, Liou JP, Teng CM, Pan SL.

Clin Epigenetics. 2019 May 29;11(1):85. doi: 10.1186/s13148-019-0681-6.


ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma.

Wu YJ, Ko BS, Liang SM, Lu YJ, Jan YJ, Jiang SS, Shyue SK, Chen L, Liou JY.

Cell Death Dis. 2019 May 28;10(6):408. doi: 10.1038/s41419-019-1651-9.


Effect of Income Heterogeneity on Valuation of Mortality Risk in Taiwan: An Application of Unconditional Quantile Regression Method.

Liou JL.

Int J Environ Res Public Health. 2019 May 9;16(9). pii: E1620. doi: 10.3390/ijerph16091620.


Efficacy and Long-Term Safety of H. pylori Eradication for Gastric Cancer Prevention.

Liou JM, Lee YC, El-Omar EM, Wu MS.

Cancers (Basel). 2019 Apr 28;11(5). pii: E593. doi: 10.3390/cancers11050593. Review.


MPT0G413, A Novel HDAC6-Selective Inhibitor, and Bortezomib Synergistically Exert Anti-tumor Activity in Multiple Myeloma Cells.

Huang FI, Wu YW, Sung TY, Liou JP, Lin MH, Pan SL, Yang CR.

Front Oncol. 2019 Apr 9;9:249. doi: 10.3389/fonc.2019.00249. eCollection 2019.


Developing A Sustainable Urban-Environmental Quality Evaluation System in China Based on A Hybrid Model.

Shao Q, Weng SS, Liou JJH, Lo HW, Jiang H.

Int J Environ Res Public Health. 2019 Apr 22;16(8). pii: E1434. doi: 10.3390/ijerph16081434.


Lateral Order and Self-Organized Morphology of Diblock Copolymer Micellar Films.

Liou JY, Sun YS.

Polymers (Basel). 2018 May 29;10(6). pii: E597. doi: 10.3390/polym10060597.


Opioid and propofol pharmacodynamics modeling during brain mapping in awake craniotomy.

Liou JY, Wang HY, Tsou MY, Chang WK, Kuo IT, Ting CK.

J Chin Med Assoc. 2019 May;82(5):390-395. doi: 10.1097/JCMA.0000000000000092.


Lactobacillus suantsaii sp. nov., isolated from suan-tsai, a traditional Taiwanese fermented mustard green.

Liou JS, Huang CH, Wang CL, Lee AY, Mori K, Tamura T, Watanabe M, Blom J, Huang L, Watanabe K.

Int J Syst Evol Microbiol. 2019 May;69(5):1484-1489. doi: 10.1099/ijsem.0.003346. Epub 2019 Mar 19.


STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death.

Wu J, Chen YJ, Dobbs N, Sakai T, Liou J, Miner JJ, Yan N.

J Exp Med. 2019 Apr 1;216(4):867-883. doi: 10.1084/jem.20182192. Epub 2019 Mar 18.


Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo.

Hsieh YL, Tu HJ, Pan SL, Liou JP, Yang CR.

Biochim Biophys Acta Mol Cell Res. 2019 Jun;1866(6):992-1003. doi: 10.1016/j.bbamcr.2019.03.003. Epub 2019 Mar 10.


From germ theory to germ therapy.

Chen CC, Chen YN, Liou JM, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

Kaohsiung J Med Sci. 2019 Feb;35(2):73-82. doi: 10.1002/kjm2.12011. Review.


Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites.

Mikkelsen M, Rimbault DL, Barker PB, Bhattacharyya PK, Brix MK, Buur PF, Cecil KM, Chan KL, Chen DY, Craven AR, Cuypers K, Dacko M, Duncan NW, Dydak U, Edmondson DA, Ende G, Ersland L, Forbes MA, Gao F, Greenhouse I, Harris AD, He N, Heba S, Hoggard N, Hsu TW, Jansen JFA, Kangarlu A, Lange T, Lebel RM, Li Y, Lin CE, Liou JK, Lirng JF, Liu F, Long JR, Ma R, Maes C, Moreno-Ortega M, Murray SO, Noah S, Noeske R, Noseworthy MD, Oeltzschner G, Porges EC, Prisciandaro JJ, Puts NAJ, Roberts TPL, Sack M, Sailasuta N, Saleh MG, Schallmo MP, Simard N, Stoffers D, Swinnen SP, Tegenthoff M, Truong P, Wang G, Wilkinson ID, Wittsack HJ, Woods AJ, Xu H, Yan F, Zhang C, Zipunnikov V, Zöllner HJ, Edden RAE.

Neuroimage. 2019 May 1;191:537-548. doi: 10.1016/j.neuroimage.2019.02.059. Epub 2019 Mar 3.


Analysis of Phosphatidylinositol Transfer at ER-PM Junctions in Receptor-Stimulated Live Cells.

Chang CL, Liou J.

Methods Mol Biol. 2019;1949:1-11. doi: 10.1007/978-1-4939-9136-5_1.


Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents.

Liu YM, Chen CH, Yeh TK, Liou JP.

Future Med Chem. 2019 May;11(9):959-974. doi: 10.4155/fmc-2018-0564. Epub 2019 Feb 21.


Recent insights into mammalian ER-PM junctions.

Chen YJ, Quintanilla CG, Liou J.

Curr Opin Cell Biol. 2019 Apr;57:99-105. doi: 10.1016/ Epub 2019 Feb 8. Review.


Increased Type 2 Innate Lymphoid Cells in Patients with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome.

Tsai YG, Liou JH, Hung SI, Chen CB, Chiu TM, Wang CW, Chung WH.

J Invest Dermatol. 2019 Aug;139(8):1722-1731. doi: 10.1016/j.jid.2018.10.048. Epub 2019 Feb 5.


Surface Modification of Electrospun Scaffolds for Endothelialization of Tissue-Engineered Vascular Grafts Using Human Cord Blood-Derived Endothelial Cells.

Ardila DC, Liou JJ, Maestas D, Slepian MJ, Badowski M, Wagner WR, Harris D, Vande Geest JP.

J Clin Med. 2019 Feb 4;8(2). pii: E185. doi: 10.3390/jcm8020185.


Cordycepin Suppresses Endothelial Cell Proliferation, Migration, Angiogenesis, and Tumor Growth by Regulating Focal Adhesion Kinase and p53.

Lin YT, Liang SM, Wu YJ, Wu YJ, Lu YJ, Jan YJ, Ko BS, Chuang YJ, Shyue SK, Kuo CC, Liou JY.

Cancers (Basel). 2019 Feb 1;11(2). pii: E168. doi: 10.3390/cancers11020168.

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