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Items: 1 to 50 of 95

1.

Adenosine Deaminase-2-Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p.

Samra YA, Saleh HM, Hussein KA, Elsherbiny NM, Ibrahim AS, Elmasry K, Fulzele S, El-Shishtawy MM, Eissa LA, Al-Shabrawey M, Liou GI.

Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):933-943. doi: 10.1167/iovs.16-19782.

2.

Olive and ginkgo extracts as potential cataract therapy with differential inhibitory activity on aldose reductase.

Elimam DM, Ibrahim AS, Liou GI, Badria FA.

Drug Discov Ther. 2017 Mar 22;11(1):41-46. doi: 10.5582/ddt.2016.01071. Epub 2017 Jan 26.

3.

Cepharanthine and Piperine ameliorate diabetic nephropathy in rats: role of NF-κB and NLRP3 inflammasome.

Samra YA, Said HS, Elsherbiny NM, Liou GI, El-Shishtawy MM, Eissa LA.

Life Sci. 2016 Jul 15;157:187-199. doi: 10.1016/j.lfs.2016.06.002. Epub 2016 Jun 3.

PMID:
27266851
4.

Anti-inflammatory role of sesamin in STZ induced mice model of diabetic retinopathy.

Ahmad S, ElSherbiny NM, Jamal MS, Alzahrani FA, Haque R, Khan R, Zaidi SK, AlQahtani MH, Liou GI, Bhatia K.

J Neuroimmunol. 2016 Jun 15;295-296:47-53. doi: 10.1016/j.jneuroim.2016.04.002. Epub 2016 Apr 12.

PMID:
27235348
5.

MicroRNA-146b-3p regulates retinal inflammation by suppressing adenosine deaminase-2 in diabetes.

Fulzele S, El-Sherbini A, Ahmad S, Sangani R, Matragoon S, El-Remessy A, Radhakrishnan R, Liou GI.

Biomed Res Int. 2015;2015:846501. doi: 10.1155/2015/846501. Epub 2015 Mar 1.

6.

Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy.

Ahmad S, Elsherbiny NM, Bhatia K, Elsherbini AM, Fulzele S, Liou GI.

J Neuroimmunol. 2014 Dec 15;277(1-2):96-104. doi: 10.1016/j.jneuroim.2014.10.006. Epub 2014 Oct 22.

PMID:
25457840
7.

Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke.

Ahmad S, Elsherbiny NM, Haque R, Khan MB, Ishrat T, Shah ZA, Khan MM, Ali M, Jamal A, Katare DP, Liou GI, Bhatia K.

Neurotoxicology. 2014 Dec;45:100-10. doi: 10.1016/j.neuro.2014.10.002. Epub 2014 Oct 12.

PMID:
25316624
8.

Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms.

Pye C, Elsherbiny NM, Ibrahim AS, Liou GI, Chadli A, Al-Shabrawey M, Elmarakby AA.

Pharmacol Res. 2014 Jul;85:45-54. doi: 10.1016/j.phrs.2014.05.004. Epub 2014 May 17.

9.

Sigma receptor ligand, (+)-pentazocine, suppresses inflammatory responses of retinal microglia.

Zhao J, Ha Y, Liou GI, Gonsalvez GB, Smith SB, Bollinger KE.

Invest Ophthalmol Vis Sci. 2014 May 8;55(6):3375-84. doi: 10.1167/iovs.13-12823.

10.

Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein.

Sato K, Li S, Gordon WC, He J, Liou GI, Hill JM, Travis GH, Bazan NG, Jin M.

J Neurosci. 2013 Oct 30;33(44):17458-68. doi: 10.1523/JNEUROSCI.1380-13.2013.

11.

Potential role of A2A adenosine receptor in traumatic optic neuropathy.

Ahmad S, Fatteh N, El-Sherbiny NM, Naime M, Ibrahim AS, El-Sherbini AM, El-Shafey SA, Khan S, Fulzele S, Gonzales J, Liou GI.

J Neuroimmunol. 2013 Nov 15;264(1-2):54-64. doi: 10.1016/j.jneuroim.2013.09.015. Epub 2013 Sep 21.

PMID:
24090652
12.

Regulation of vitamin C transporter in the type 1 diabetic mouse bone and bone marrow.

Sangani R, Naime M, Zakhary I, Ahmad S, Chutkan N, Zhu A, Ha Y, Hamrick M, Isales C, Elsalanty M, Smith S, Liou GI, Fulzele S.

Exp Mol Pathol. 2013 Dec;95(3):298-306. doi: 10.1016/j.yexmp.2013.08.007. Epub 2013 Aug 30.

PMID:
23999113
13.

ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy.

Elsherbiny NM, Ahmad S, Naime M, Elsherbini AM, Fulzele S, Al-Gayyar MM, Eissa LA, El-Shishtawy MM, Liou GI.

Life Sci. 2013 Jul 30;93(2-3):78-88. doi: 10.1016/j.lfs.2013.05.024. Epub 2013 Jun 12.

PMID:
23770229
14.

Potential roles of adenosine deaminase-2 in diabetic retinopathy.

Elsherbiny NM, Naime M, Ahmad S, Elsherbini AM, Mohammad S, Fulzele S, El-Remessy AB, Al-Gayyar MM, Eissa LA, El-Shishtawy MM, Han G, White R, Haroldo TF, Liou GI.

Biochem Biophys Res Commun. 2013 Jul 5;436(3):355-61. doi: 10.1016/j.bbrc.2013.05.023. Epub 2013 May 16.

PMID:
23685153
15.

Loss of thioredoxin function in retinas of mice overexpressing amyloid β.

Lamoke F, Ripandelli G, Webster S, Montemari A, Maraschi A, Martin P, Marcus DM, Liou GI, Bartoli M.

Free Radic Biol Med. 2012 Aug 1;53(3):577-88. doi: 10.1016/j.freeradbiomed.2012.04.010. Epub 2012 Apr 21.

PMID:
22564527
16.

Tyrosine kinase inhibitor, genistein, reduces renal inflammation and injury in streptozotocin-induced diabetic mice.

Elmarakby AA, Ibrahim AS, Faulkner J, Mozaffari MS, Liou GI, Abdelsayed R.

Vascul Pharmacol. 2011 Nov-Dec;55(5-6):149-56. doi: 10.1016/j.vph.2011.07.007. Epub 2011 Jul 23.

PMID:
21807121
17.

Exaggerated eye growth in IRBP-deficient mice in early development.

Wisard J, Faulkner A, Chrenek MA, Waxweiler T, Waxweiler W, Donmoyer C, Liou GI, Craft CM, Schmid GF, Boatright JH, Pardue MT, Nickerson JM.

Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):5804-11. doi: 10.1167/iovs.10-7129.

18.

Role of adenosine in diabetic retinopathy.

Liou GI, Ahmad S, Naime M, Fatteh N, Ibrahim AS.

J Ocul Biol Dis Infor. 2011 Jun;4(1-2):19-24. doi: 10.1007/s12177-011-9067-5. Epub 2012 Jan 11.

19.

A(₂A) adenosine receptor (A(₂A)AR) as a therapeutic target in diabetic retinopathy.

Ibrahim AS, El-Shishtawy MM, Zhang W, Caldwell RB, Liou GI.

Am J Pathol. 2011 May;178(5):2136-45. doi: 10.1016/j.ajpath.2011.01.018.

20.

Retinal microglial activation and inflammation induced by amadori-glycated albumin in a rat model of diabetes.

Ibrahim AS, El-Remessy AB, Matragoon S, Zhang W, Patel Y, Khan S, Al-Gayyar MM, El-Shishtawy MM, Liou GI.

Diabetes. 2011 Apr;60(4):1122-33. doi: 10.2337/db10-1160. Epub 2011 Feb 11.

21.

Opioid receptor activation: suppression of ischemia/reperfusion-induced production of TNF-α in the retina.

Husain S, Liou GI, Crosson CE.

Invest Ophthalmol Vis Sci. 2011 Apr 20;52(5):2577-83. doi: 10.1167/iovs.10-5629. Print 2011 Apr.

22.

Genistein attenuates retinal inflammation associated with diabetes by targeting of microglial activation.

Ibrahim AS, El-Shishtawy MM, Peña A Jr, Liou GI.

Mol Vis. 2010 Oct 8;16:2033-42.

23.

Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development.

Liou G, El-Remessy A, Ibrahim A, Caldwell R, Khalifa Y, Gunes A, Nussbaum J.

Curr Pharmacogenomics Person Med. 2009 Sep;7(3):215-222.

24.

Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes.

El-Remessy AB, Khalifa Y, Ola S, Ibrahim AS, Liou GI.

Mol Vis. 2010 Aug 4;16:1487-95. Retraction in: Mol Vis. 2014;20:1226.

25.

Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation.

Liou GI.

World J Diabetes. 2010 Mar 15;1(1):12-8. doi: 10.4239/wjd.v1.i1.12.

26.

Role of IL-6 in angiotensin II-induced retinal vascular inflammation.

Rojas M, Zhang W, Lee DL, Romero MJ, Nguyen DT, Al-Shabrawey M, Tsai NT, Liou GI, Brands MW, Caldwell RW, Caldwell RB.

Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1709-18. doi: 10.1167/iovs.09-3375. Epub 2009 Oct 15.

27.

Normal cone function requires the interphotoreceptor retinoid binding protein.

Parker RO, Fan J, Nickerson JM, Liou GI, Crouch RK.

J Neurosci. 2009 Apr 8;29(14):4616-21. doi: 10.1523/JNEUROSCI.0063-09.2009.

28.

NAD(P)H oxidase-dependent regulation of CCL2 production during retinal inflammation.

Zhang W, Rojas M, Lilly B, Tsai NT, Lemtalsi T, Liou GI, Caldwell RW, Caldwell RB.

Invest Ophthalmol Vis Sci. 2009 Jun;50(6):3033-40. doi: 10.1167/iovs.08-2676. Epub 2009 Feb 21.

29.

Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation.

El-Remessy AB, Tang Y, Zhu G, Matragoon S, Khalifa Y, Liu EK, Liu JY, Hanson E, Mian S, Fatteh N, Liou GI.

Mol Vis. 2008;14:2190-203. Epub 2008 Dec 3. Retraction in: Mol Vis. 2014;20:1227.

30.

Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor.

Liou GI, Auchampach JA, Hillard CJ, Zhu G, Yousufzai B, Mian S, Khan S, Khalifa Y.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5526-31. doi: 10.1167/iovs.08-2196. Epub 2008 Jul 18.

31.

Repertoire analysis and new pathogenic epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) mice.

Cortes LM, Mattapallil MJ, Silver PB, Donoso LA, Liou GI, Zhu W, Chan CC, Caspi RR.

Invest Ophthalmol Vis Sci. 2008 May;49(5):1946-56. doi: 10.1167/iovs.07-0868.

32.

Peroxynitrite mediates retinal neurodegeneration by inhibiting nerve growth factor survival signaling in experimental and human diabetes.

Ali TK, Matragoon S, Pillai BA, Liou GI, El-Remessy AB.

Diabetes. 2008 Apr;57(4):889-98. doi: 10.2337/db07-1669. Epub 2008 Feb 19.

33.

Neuroprotective and intraocular pressure-lowering effects of (-)Delta9-tetrahydrocannabinol in a rat model of glaucoma.

Crandall J, Matragoon S, Khalifa YM, Borlongan C, Tsai NT, Caldwell RB, Liou GI.

Ophthalmic Res. 2007;39(2):69-75. Epub 2007 Feb 2.

PMID:
17284931
34.

Spontaneous autoimmunity prevented by thymic expression of a single self-antigen.

DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Fong L, Anderson MS.

J Exp Med. 2006 Nov 27;203(12):2727-35. Epub 2006 Nov 20. Erratum in: J Exp Med. 2007 Jan 22;204(1):203. Caspi, Rachel [corrected to Caspi, Rachel R].

35.

Endogenous IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity.

Grajewski RS, Silver PB, Agarwal RK, Su SB, Chan CC, Liou GI, Caspi RR.

J Exp Med. 2006 Apr 17;203(4):851-6. Epub 2006 Apr 3.

36.

Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes.

El-Remessy AB, Al-Shabrawey M, Khalifa Y, Tsai NT, Caldwell RB, Liou GI.

Am J Pathol. 2006 Jan;168(1):235-44.

37.

Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress.

Caldwell RB, Bartoli M, Behzadian MA, El-Remessy AE, Al-Shabrawey M, Platt DH, Liou GI, Caldwell RW.

Curr Drug Targets. 2005 Jun;6(4):511-24. Review.

PMID:
16026270
38.

Alternative splicing of the APC gene in the neural retina and retinal pigment epithelium.

Liou GI, Samuel S, Matragoon S, Goss KH, Santoro I, Groden J, Hunt RC, Wang F, Miller SS, Caldwell RB, Rustgi AK, Singh H, Marcus DM.

Mol Vis. 2004 Jun 14;10:383-91.

39.

An immunologically privileged retinal antigen elicits tolerance: major role for central selection mechanisms.

Avichezer D, Grajewski RS, Chan CC, Mattapallil MJ, Silver PB, Raber JA, Liou GI, Wiggert B, Lewis GM, Donoso LA, Caspi RR.

J Exp Med. 2003 Dec 1;198(11):1665-76.

40.

Interphotoreceptor retinoid-binding protein (IRBP)-deficient C57BL/6 mice have enhanced immunological and immunopathogenic responses to IRBP and an altered recognition of IRBP epitopes.

Avichezer D, Liou GI, Chan CC, Lewis GM, Wiggert B, Donoso LA, Nickerson JM, Crawford MA, Caspi RR.

J Autoimmun. 2003 Nov;21(3):185-94.

PMID:
14599843
41.

Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite.

El-Remessy AB, Khalil IE, Matragoon S, Abou-Mohamed G, Tsai NJ, Roon P, Caldwell RB, Caldwell RW, Green K, Liou GI.

Am J Pathol. 2003 Nov;163(5):1997-2008.

42.

MAP kinase and beta-catenin signaling in HGF induced RPE migration.

Liou GI, Matragoon S, Samuel S, Behzadian MA, Tsai NT, Gu X, Roon P, Hunt DM, Hunt RC, Caldwell RB, Marcus DM.

Mol Vis. 2002 Dec 20;8:483-93.

43.

HGF regulation of RPE proliferation in an IL-1beta/retinal hole-induced rabbit model of PVR.

Liou GI, Pakalnis VA, Matragoon S, Samuel S, Behzadian MA, Baker J, Khalil IE, Roon P, Caldwell RB, Hunt RC, Marcus DM.

Mol Vis. 2002 Dec 20;8:494-501.

44.

Sequence analysis of the mouse IRBP gene and cDNA.

Shuler RK Jr, Gross E, He WY, Liou GI, Nickerson JM.

Curr Eye Res. 2002 May;24(5):354-67.

PMID:
12434304
45.

Regulation of interphotoreceptor retinoid-binding protein (IRBP) gene expression by cAMP in differentiated retinoblastoma cells.

El-Remessy AE, Rabie AM, El-Shishtawy MM, Eissa LA, Liou GI.

Mol Vis. 2000 Dec 8;6:243-51. Retraction in: Mol Vis. 2014;20:1225.

46.

Ultrastructural and ERG findings in mice with adenomatous polyposis coli gene disruption.

Marcus DM, Rustgi AK, Defoe D, Kucherlapati R, Edelmann W, Hamasaki D, Liou GI, Smith SB.

Mol Vis. 2000 Sep 8;6:169-77.

47.

The rhodopsin cycle is preserved in IRBP "knockout" mice despite abnormalities in retinal structure and function.

Ripps H, Peachey NS, Xu X, Nozell SE, Smith SB, Liou GI.

Vis Neurosci. 2000 Jan-Feb;17(1):97-105.

PMID:
10750831
48.

Expression of phosphatidylinositol 3-kinase during EGF-stimulated wound repair in rabbit corneal epithelium.

Zhang Y, Liou GI, Gulati AK, Akhtar RA.

Invest Ophthalmol Vis Sci. 1999 Nov;40(12):2819-26.

PMID:
10549641
49.
50.

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