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Items: 1 to 50 of 214

1.

Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease.

Dennis J, Sealock J, Levinson RT, Farber-Eger E, Franco J, Fong S, Straub P, Hucks D, Song WL, Linton MF, Fontanillas P, Elson SL, Ruderfer D, Abdellaoui A, Sanchez-Roige S, Palmer AA, Boomsma DI, Cox NJ, Chen G, Mosley JD, Wells QS, Davis LK.

Mol Psychiatry. 2019 Dec 3. doi: 10.1038/s41380-019-0614-y. [Epub ahead of print]

PMID:
31796895
2.

Modified sites and functional consequences of 4-oxo-2-nonenal adducts in HDL that are elevated in familial hypercholesterolemia.

May-Zhang LS, Yermalitsky V, Melchior JT, Morris J, Tallman KA, Borja MS, Pleasent T, Amarnath V, Song W, Yancey PG, Davidson WS, Linton MF, Davies SS.

J Biol Chem. 2019 Oct 30. pii: jbc.RA119.009424. doi: 10.1074/jbc.RA119.009424. [Epub ahead of print]

3.

A Genetic Approach to the Association Between PCSK9 and Sepsis.

Feng Q, Wei WQ, Chaugai S, Carranza Leon BG, Kawai V, Carranza Leon DA, Jiang L, Zhong X, Liu G, Ihegword A, Shaffer CM, Linton MF, Chung CP, Stein CM.

JAMA Netw Open. 2019 Sep 4;2(9):e1911130. doi: 10.1001/jamanetworkopen.2019.11130.

4.

Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry.

Duell PB, Gidding SS, Andersen RL, Knickelbine T, Anderson L, Gianos E, Shrader P, Kindt I, O'Brien EC, McCann D, Hemphill LC, Ahmed CD, Martin SS, Larry JA, Ahmad ZS, Kullo IJ, Underberg JA, Guyton J, Thompson P, Wilemon K, Roe MT, Rader DJ, Cuchel M, Linton MF, Shapiro MD, Moriarty PM, Knowles JW.

Atherosclerosis. 2019 Oct;289:85-93. doi: 10.1016/j.atherosclerosis.2019.08.007. Epub 2019 Aug 19.

5.

Imaging mass spectrometry reveals heterogeneity of proliferation and metabolism in atherosclerosis.

Guillermier C, Doherty SP, Whitney AG, Babaev VR, Linton MF, Steinhauser ML, Brown JD.

JCI Insight. 2019 Jun 6;4(11). pii: 128528. doi: 10.1172/jci.insight.128528. eCollection 2019 Jun 6.

6.

Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis.

Linton MF, Moslehi JJ, Babaev VR.

Int J Mol Sci. 2019 Jun 1;20(11). pii: E2703. doi: 10.3390/ijms20112703. Review.

7.

PCSK9 Inhibitor Use in the Real World: Data From the National Patient-Centered Research Network.

Chamberlain AM, Gong Y, Shaw KM, Bian J, Song WL, Linton MF, Fonseca V, Price-Haywood E, Guhl E, King JB, Shah RU, Puro J, Shenkman E, Pawloski PA, Margolis KL, Hernandez AF, Cooper-DeHoff RM.

J Am Heart Assoc. 2019 May 7;8(9):e011246. doi: 10.1161/JAHA.118.011246.

8.

Lipoprotein modulation of proteinuric renal injury.

Tsuchida Y, Zhong J, Otsuka T, Dikalova A, Pastan I, Anantharamaiah GM, Linton MF, Yancey PG, Ikizler TA, Fogo AB, Yang H, Kon V.

Lab Invest. 2019 Jul;99(8):1107-1116. doi: 10.1038/s41374-019-0253-6. Epub 2019 Apr 24.

9.

IL-1 Inhibition and Function of the HDL-Containing Fraction of Plasma in Patients with Stages 3 to 5 CKD.

Hung AM, Tsuchida Y, Nowak KL, Sarkar S, Chonchol M, Whitfield V, Salas N, Dikalova A, Yancey PG, Huang J, Linton MF, Ikizler TA, Kon V.

Clin J Am Soc Nephrol. 2019 May 7;14(5):702-711. doi: 10.2215/CJN.04360418. Epub 2019 Apr 23.

PMID:
31015261
10.

Response by Mueller et al to Letter Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages".

Mueller PA, Zhu L, Tavori H, Huynh KT, Giunzioni I, Stafford JM, Linton MF, Fazio S.

Circulation. 2019 Apr 16;139(16):1983-1984. doi: 10.1161/CIRCULATIONAHA.119.039682. No abstract available.

PMID:
30986111
11.

Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion.

Sedgeman LR, Beysen C, Ramirez Solano MA, Michell DL, Sheng Q, Zhao S, Turner S, Linton MF, Vickers KC.

Sci Rep. 2019 Mar 7;9(1):3803. doi: 10.1038/s41598-019-40338-7.

12.

Dual inhibition of endothelial miR-92a-3p and miR-489-3p reduces renal injury-associated atherosclerosis.

Wiese CB, Zhong J, Xu ZQ, Zhang Y, Ramirez Solano MA, Zhu W, Linton MF, Sheng Q, Kon V, Vickers KC.

Atherosclerosis. 2019 Mar;282:121-131. doi: 10.1016/j.atherosclerosis.2019.01.023. Epub 2019 Jan 30.

PMID:
30731284
13.

Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor-/- Mice Improves Indices of Cardiometabolic Disease.

May-Zhang LS, Chen Z, Dosoky NS, Yancey PG, Boyd KL, Hasty AH, Linton MF, Davies SS.

Sci Rep. 2019 Jan 23;9(1):420. doi: 10.1038/s41598-018-37373-1.

14.

Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection.

Feng Q, Wei WQ, Chaugai S, Leon BGC, Mosley JD, Leon DAC, Jiang L, Ihegword A, Shaffer CM, Linton MF, Chung CP, Stein CM.

JAMA Netw Open. 2019 Jan 4;2(1):e187223. doi: 10.1001/jamanetworkopen.2018.7223.

15.

Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation.

Brophy ML, Dong Y, Tao H, Yancey PG, Song K, Zhang K, Wen A, Wu H, Lee Y, Malovichko MV, Sithu SD, Wong S, Yu L, Kocher O, Bischoff J, Srivastava S, Linton MF, Ley K, Chen H.

Circ Res. 2019 Feb 15;124(4):e6-e19. doi: 10.1161/CIRCRESAHA.118.313028.

PMID:
30595089
16.

Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.

Babaev VR, Ding L, Zhang Y, May JM, Ramsey SA, Vickers KC, Linton MF.

Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):156-169. doi: 10.1161/ATVBAHA.118.312206.

PMID:
30567482
17.

Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records.

Feng Q, Wei WQ, Chung CP, Levinson RT, Sundermann AC, Mosley JD, Bastarache L, Ferguson JF, Cox NJ, Roden DM, Denny JC, Linton MF, Edwards DRV, Stein CM.

PLoS Med. 2018 Aug 28;15(8):e1002642. doi: 10.1371/journal.pmed.1002642. eCollection 2018 Aug.

18.

Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins.

Allen RM, Zhao S, Ramirez Solano MA, Zhu W, Michell DL, Wang Y, Shyr Y, Sethupathy P, Linton MF, Graf GA, Sheng Q, Vickers KC.

J Extracell Vesicles. 2018 Aug 13;7(1):1506198. doi: 10.1080/20013078.2018.1506198. eCollection 2018.

19.

Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel.

Sturm AC, Knowles JW, Gidding SS, Ahmad ZS, Ahmed CD, Ballantyne CM, Baum SJ, Bourbon M, Carrié A, Cuchel M, de Ferranti SD, Defesche JC, Freiberger T, Hershberger RE, Hovingh GK, Karayan L, Kastelein JJP, Kindt I, Lane SR, Leigh SE, Linton MF, Mata P, Neal WA, Nordestgaard BG, Santos RD, Harada-Shiba M, Sijbrands EJ, Stitziel NO, Yamashita S, Wilemon KA, Ledbetter DH, Rader DJ; Convened by the Familial Hypercholesterolemia Foundation.

J Am Coll Cardiol. 2018 Aug 7;72(6):662-680. doi: 10.1016/j.jacc.2018.05.044. Review.

20.

Exercise is Associated With Increased Small HDL Particle Concentration and Decreased Vascular Stiffness in Rheumatoid Arthritis.

Byram KW, Oeser AM, Linton MF, Fazio S, Stein CM, Ormseth MJ.

J Clin Rheumatol. 2018 Dec;24(8):417-421. doi: 10.1097/RHU.0000000000000809.

21.

Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages.

Mueller PA, Zhu L, Tavori H, Huynh K, Giunzioni I, Stafford JM, Linton MF, Fazio S.

Circulation. 2018 Oct 23;138(17):1850-1863. doi: 10.1161/CIRCULATIONAHA.117.031702.

22.

Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function.

May-Zhang LS, Yermalitsky V, Huang J, Pleasent T, Borja MS, Oda MN, Jerome WG, Yancey PG, Linton MF, Davies SS.

J Biol Chem. 2018 Jun 15;293(24):9176-9187. doi: 10.1074/jbc.RA117.001099. Epub 2018 Apr 30.

23.

Angiotensin receptor blocker vs ACE inhibitor effects on HDL functionality in patients on maintenance hemodialysis.

Kaseda R, Tsuchida Y, Gamboa JL, Zhong J, Zhang L, Yang H, Dikalova A, Bian A, Davies S, Fogo AF, Linton MF, Brown NJ, Ikizler TA, Kon V.

Nutr Metab Cardiovasc Dis. 2018 Jun;28(6):582-591. doi: 10.1016/j.numecd.2018.02.020. Epub 2018 Mar 8.

24.

Loss of Rictor in Monocyte/Macrophages Suppresses Their Proliferation and Viability Reducing Atherosclerosis in LDLR Null Mice.

Babaev VR, Huang J, Ding L, Zhang Y, May JM, Linton MF.

Front Immunol. 2018 Feb 13;9:215. doi: 10.3389/fimmu.2018.00215. eCollection 2018.

25.

Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding.

Zhu L, Shi J, Luu TN, Neuman JC, Trefts E, Yu S, Palmisano BT, Wasserman DH, Linton MF, Stafford JM.

Mol Metab. 2018 Feb;8:106-116. doi: 10.1016/j.molmet.2017.12.012. Epub 2017 Dec 29.

26.

High-Density Lipoprotein Cholesterol Concentration and Acute Kidney Injury After Cardiac Surgery.

Smith LE, Smith DK, Blume JD, Linton MF, Billings FT 4th.

J Am Heart Assoc. 2017 Dec 9;6(12). pii: e006975. doi: 10.1161/JAHA.117.006975.

27.

Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FH™ patient registry.

Amrock SM, Duell PB, Knickelbine T, Martin SS, O'Brien EC, Watson KE, Mitri J, Kindt I, Shrader P, Baum SJ, Hemphill LC, Ahmed CD, Andersen RL, Kullo IJ, McCann D, Larry JA, Murray MF, Fishberg R, Guyton JR, Wilemon K, Roe MT, Rader DJ, Ballantyne CM, Underberg JA, Thompson P, Duffy D, Linton MF, Shapiro MD, Moriarty PM, Knowles JW, Ahmad ZS.

Atherosclerosis. 2017 Dec;267:19-26. doi: 10.1016/j.atherosclerosis.2017.10.006. Epub 2017 Oct 6.

PMID:
29080546
28.

A case of severe acquired hypertriglyceridemia in a 7-year-old girl.

Lilley JS, Linton MF, Kelley JC, Graham TB, Fazio S, Tavori H.

J Clin Lipidol. 2017 Nov - Dec;11(6):1480-1484. doi: 10.1016/j.jacl.2017.08.003. Epub 2017 Aug 12.

PMID:
28916403
29.

Loss of SPRR3 in ApoE-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs.

Lietman CD, Segedy AK, Li B, Fazio S, Atkinson JB, Linton MF, Young PP.

PLoS One. 2017 Sep 8;12(9):e0184620. doi: 10.1371/journal.pone.0184620. eCollection 2017.

30.

Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.

Beigneux AP, Miyashita K, Ploug M, Blom DJ, Ai M, Linton MF, Khovidhunkit W, Dufour R, Garg A, McMahon MA, Pullinger CR, Sandoval NP, Hu X, Allan CM, Larsson M, Machida T, Murakami M, Reue K, Tontonoz P, Goldberg IJ, Moulin P, Charrière S, Fong LG, Nakajima K, Young SG.

N Engl J Med. 2017 Apr 27;376(17):1647-1658. doi: 10.1056/NEJMoa1611930. Epub 2017 Apr 5.

31.

SR-BI: A Multifunctional Receptor in Cholesterol Homeostasis and Atherosclerosis.

Linton MF, Tao H, Linton EF, Yancey PG.

Trends Endocrinol Metab. 2017 Jun;28(6):461-472. doi: 10.1016/j.tem.2017.02.001. Epub 2017 Mar 1. Review.

32.

Net cholesterol efflux capacity of HDL enriched serum and coronary atherosclerosis in rheumatoid arthritis.

Ormseth MJ, Yancey PG, Yamamoto S, Oeser AM, Gebretsadik T, Shintani A, Linton MF, Fazio S, Davies SS, Roberts LJ 2nd, Vickers KC, Raggi P, Kon V, Stein CM.

IJC Metab Endocr. 2016 Dec;13:6-11. doi: 10.1016/j.ijcme.2016.08.002. Epub 2016 Aug 28.

33.

Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL.

Hu X, Sleeman MW, Miyashita K, Linton MF, Allan CM, He C, Larsson M, Tu Y, Sandoval NP, Jung RS, Mapar A, Machida T, Murakami M, Nakajima K, Ploug M, Fong LG, Young SG, Beigneux AP.

J Lipid Res. 2017 Jan;58(1):208-215. doi: 10.1194/jlr.M072462. Epub 2016 Nov 15.

34.

Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis.

Linton MF, Babaev VR, Huang J, Linton EF, Tao H, Yancey PG.

Circ J. 2016 Oct 25;80(11):2259-2268. Epub 2016 Oct 8. Review.

35.

US physician practices for diagnosing familial hypercholesterolemia: data from the CASCADE-FH registry.

Ahmad ZS, Andersen RL, Andersen LH, O'Brien EC, Kindt I, Shrader P, Vasandani C, Newman CB, deGoma EM, Baum SJ, Hemphill LC, Hudgins LC, Ahmed CD, Kullo IJ, Gidding SS, Duffy D, Neal W, Wilemon K, Roe MT, Rader DJ, Ballantyne CM, Linton MF, Duell PB, Shapiro MD, Moriarty PM, Knowles JW.

J Clin Lipidol. 2016 Sep-Oct;10(5):1223-9. doi: 10.1016/j.jacl.2016.07.011. Epub 2016 Aug 6.

36.

Loss of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-α Inhibition.

Zhu L, Giunzioni I, Tavori H, Covarrubias R, Ding L, Zhang Y, Ormseth M, Major AS, Stafford JM, Linton MF, Fazio S.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1483-95. doi: 10.1161/ATVBAHA.116.307736. Epub 2016 Jun 30.

37.

Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice.

Babaev VR, Yeung M, Erbay E, Ding L, Zhang Y, May JM, Fazio S, Hotamisligil GS, Linton MF.

Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1122-31. doi: 10.1161/ATVBAHA.116.307580. Epub 2016 Apr 21.

38.

Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry.

deGoma EM, Ahmad ZS, O'Brien EC, Kindt I, Shrader P, Newman CB, Pokharel Y, Baum SJ, Hemphill LC, Hudgins LC, Ahmed CD, Gidding SS, Duffy D, Neal W, Wilemon K, Roe MT, Rader DJ, Ballantyne CM, Linton MF, Duell PB, Shapiro MD, Moriarty PM, Knowles JW.

Circ Cardiovasc Genet. 2016 Jun;9(3):240-9. doi: 10.1161/CIRCGENETICS.116.001381. Epub 2016 Mar 24.

39.

Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid Arthritis.

Ormseth MJ, Yancey PG, Solus JF, Bridges SL Jr, Curtis JR, Linton MF, Fazio S, Davies SS, Roberts LJ 2nd, Vickers KC, Kon V, Michael Stein C; TETRAD Investigators.

Arthritis Rheumatol. 2016 Sep;68(9):2099-105. doi: 10.1002/art.39675.

40.

Human PCSK9 promotes hepatic lipogenesis and atherosclerosis development via apoE- and LDLR-mediated mechanisms.

Tavori H, Giunzioni I, Predazzi IM, Plubell D, Shivinsky A, Miles J, Devay RM, Liang H, Rashid S, Linton MF, Fazio S.

Cardiovasc Res. 2016 May 15;110(2):268-78. doi: 10.1093/cvr/cvw053. Epub 2016 Mar 15.

41.

Macrophage IKKα Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis.

Babaev VR, Ding L, Zhang Y, May JM, Lin PC, Fazio S, Linton MF.

Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):598-607. doi: 10.1161/ATVBAHA.115.306931. Epub 2016 Feb 4.

42.

Local effects of human PCSK9 on the atherosclerotic lesion.

Giunzioni I, Tavori H, Covarrubias R, Major AS, Ding L, Zhang Y, DeVay RM, Hong L, Fan D, Predazzi IM, Rashid S, Linton MF, Fazio S.

J Pathol. 2016 Jan;238(1):52-62. doi: 10.1002/path.4630. Epub 2015 Nov 13.

43.

HDL: Beyond Atheroprotection.

Kon V, Linton MF.

J Am Soc Nephrol. 2016 Feb;27(2):341-4. doi: 10.1681/ASN.2015070793. Epub 2015 Aug 28. No abstract available.

44.

Uric acid correlates to oxidation and inflammation in opposite directions in women.

Wu SH, Shu XO, Milne G, Xiang YB, Zhang X, Cai Q, Fazio S, Linton MF, Chen H, Purdue M, Rothman N, Gao YT, Zheng W, Yang G.

Biomarkers. 2015;20(4):225-31. doi: 10.3109/1354750X.2015.1068852.

45.

Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype.

Yamamoto S, Zhong J, Yancey PG, Zuo Y, Linton MF, Fazio S, Yang H, Narita I, Kon V.

Atherosclerosis. 2015 Sep;242(1):56-64. doi: 10.1016/j.atherosclerosis.2015.06.055. Epub 2015 Jul 4.

46.

Sex-Specific Parental Effects on Offspring Lipid Levels.

Predazzi IM, Sobota RS, Sanna S, Bush WS, Bartlett J, Lilley JS, Linton MF, Schlessinger D, Cucca F, Fazio S, Williams SM.

J Am Heart Assoc. 2015 Jun 30;4(7). pii: e001951. doi: 10.1161/JAHA.115.001951.

47.

Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis.

Tao H, Yancey PG, Babaev VR, Blakemore JL, Zhang Y, Ding L, Fazio S, Linton MF.

J Lipid Res. 2015 Aug;56(8):1449-60. doi: 10.1194/jlr.M056689. Epub 2015 Jun 9.

48.
49.

Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts.

Guo L, Chen Z, Amarnath V, Yancey PG, Van Lenten BJ, Savage JR, Fazio S, Linton MF, Davies SS.

Antioxid Redox Signal. 2015 Jun 20;22(18):1633-45. doi: 10.1089/ars.2014.6078. Epub 2015 Mar 18.

50.

Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL.

Tavori H, Su YR, Yancey PG, Giunzioni I, Wilhelm AJ, Blakemore JL, Zabalawi M, Linton MF, Sorci-Thomas MG, Fazio S.

J Lipid Res. 2015 Mar;56(3):635-43. doi: 10.1194/jlr.M056408. Epub 2015 Jan 15.

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