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Items: 1 to 50 of 806

1.

Mass spectrometric evidence for the mechanism of free-radical depolymerization of various types of glycosaminoglycans.

Zhang N, Li G, Li S, Cai C, Zhang F, Linhardt RJ, Yu G.

Carbohydr Polym. 2020 Apr 1;233:115847. doi: 10.1016/j.carbpol.2020.115847. Epub 2020 Jan 10.

PMID:
32059898
2.

Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review.

Lu J, He R, Sun P, Zhang F, Linhardt RJ, Zhang A.

Int J Biol Macromol. 2020 Feb 6. pii: S0141-8130(20)30029-5. doi: 10.1016/j.ijbiomac.2020.02.035. [Epub ahead of print] Review.

PMID:
32035956
3.

Structural analysis of a novel sulfated galacto-fuco-xylo-glucurono-mannan from Sargassum fusiforme and its anti-lung cancer activity.

Jin W, Tang H, Zhang J, Wei B, Sun J, Zhang W, Zhang F, Wang H, Linhardt RJ, Zhong W.

Int J Biol Macromol. 2020 Jan 28;149:450-458. doi: 10.1016/j.ijbiomac.2020.01.275. [Epub ahead of print]

PMID:
32004605
4.

Encapsulation of phycocyanin by prebiotics and polysaccharides-based electrospun fibers and improved colon cancer prevention effects.

Wen Y, Wen P, Hu TG, Linhardt RJ, Zong MH, Wu H, Chen ZY.

Int J Biol Macromol. 2020 Jan 22;149:672-681. doi: 10.1016/j.ijbiomac.2020.01.189. [Epub ahead of print]

PMID:
31981665
5.

Comprehensive Glycomic Analysis Reveals that Human Serum Albumin Glycation Specifically Affects the Pharmacokinetics and Efficacy of Different Anticoagulant Drugs in Diabetes.

Qiu H, Jin L, Chen J, Shi M, Shi F, Wang M, Li D, Xu X, Su X, Yin X, Li W, Zhou X, Linhardt RJ, Wang Z, Chi L, Zhang Q.

Diabetes. 2020 Jan 23. pii: db190738. doi: 10.2337/db19-0738. [Epub ahead of print]

PMID:
31974145
6.

Non-anticoagulant Heparin as a Pre-exposure Prophylaxis Prevents Lyme Disease Infection.

Lin YP, Yu Y, Marcinkiewicz AL, Lederman P, Hart TM, Zhang F, Linhardt RJ.

ACS Infect Dis. 2020 Jan 30. doi: 10.1021/acsinfecdis.9b00425. [Epub ahead of print]

PMID:
31961652
7.

Extracellular matrix decorated polycaprolactone scaffolds for improved mesenchymal stem/stromal cell osteogenesis towards a patient-tailored bone tissue engineering approach.

Silva JC, Carvalho MS, Udangawa RN, Moura CS, Cabral JMS, L da Silva C, Ferreira FC, Vashishth D, Linhardt RJ.

J Biomed Mater Res B Appl Biomater. 2020 Jan 9. doi: 10.1002/jbm.b.34554. [Epub ahead of print]

PMID:
31916699
8.

Site-selective reactions for the synthesis of glycoconjugates in polysaccharide vaccine development.

Lin L, Qiao M, Zhang X, Linhardt RJ.

Carbohydr Polym. 2020 Feb 15;230:115643. doi: 10.1016/j.carbpol.2019.115643. Epub 2019 Nov 19. Review.

PMID:
31887910
9.

Regulation of PTP1B activation through disruption of redox-complex formation.

Londhe AD, Bergeron A, Curley SM, Zhang F, Rivera KD, Kannan A, Coulis G, Rizvi SHM, Kim SJ, Pappin DJ, Tonks NK, Linhardt RJ, Boivin B.

Nat Chem Biol. 2020 Feb;16(2):122-125. doi: 10.1038/s41589-019-0433-0. Epub 2019 Dec 23.

PMID:
31873221
10.

A novel route for double-layered encapsulation of probiotics with improved viability under adverse conditions.

Feng K, Huang RM, Wu RQ, Wei YS, Zong MH, Linhardt RJ, Wu H.

Food Chem. 2020 Apr 25;310:125977. doi: 10.1016/j.foodchem.2019.125977. Epub 2019 Dec 4.

PMID:
31837527
11.

Interactions between Sclerostin and Glycosaminoglycans.

Zhang F, Zhao J, Liu X, Linhardt RJ.

Glycoconj J. 2020 Feb;37(1):119-128. doi: 10.1007/s10719-019-09900-3. Epub 2019 Dec 11.

PMID:
31828567
12.

Urinary metabolomics analysis reveals the anti-diabetic effect of stachyose in high-fat diet/streptozotocin-induced type 2 diabetic rats.

Liang L, Liu G, Yu G, Zhang F, Linhardt RJ, Li Q.

Carbohydr Polym. 2020 Feb 1;229:115534. doi: 10.1016/j.carbpol.2019.115534. Epub 2019 Oct 31.

PMID:
31826396
13.
14.

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition.

Kwon PS, Ren S, Kwon SJ, Kizer ME, Kuo L, Xie M, Zhu D, Zhou F, Zhang F, Kim D, Fraser K, Kramer LD, Seeman NC, Dordick JS, Linhardt RJ, Chao J, Wang X.

Nat Chem. 2020 Jan;12(1):26-35. doi: 10.1038/s41557-019-0369-8. Epub 2019 Nov 25.

PMID:
31767992
15.

Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering.

Silva JC, Udangawa RN, Chen J, Mancinelli CD, Garrudo FFF, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ.

Mater Sci Eng C Mater Biol Appl. 2020 Feb;107:110291. doi: 10.1016/j.msec.2019.110291. Epub 2019 Oct 8.

PMID:
31761240
16.

Extraction, structure and bioactivities of the polysaccharides from Pleurotus eryngii: A review.

Zhang B, Li Y, Zhang F, Linhardt RJ, Zeng G, Zhang A.

Int J Biol Macromol. 2019 Nov 20. pii: S0141-8130(19)33821-8. doi: 10.1016/j.ijbiomac.2019.10.144. [Epub ahead of print] Review.

PMID:
31759001
17.

A novel laminin-binding protein mediates microbial-endothelial cell interactions and facilitates dissemination of Lyme disease pathogens.

Bista S, Singh P, Bernard Q, Yang X, Hart T, Lin YP, Kitsou C, Singh Rana V, Zhang F, Linhardt RJ, Zhnag K, Akins DR, Hritzo L, Kim Y, Grab DJ, Dumler JS, Pal U.

J Infect Dis. 2019 Nov 23. pii: jiz626. doi: 10.1093/infdis/jiz626. [Epub ahead of print]

PMID:
31758693
18.

Functional role of glycosaminoglycans in decellularized lung extracellular matrix.

Uhl FE, Zhang F, Pouliot RA, Uriarte JJ, Rolandsson Enes S, Han X, Ouyang Y, Xia K, Westergren-Thorsson G, Malmström A, Hallgren O, Linhardt RJ, Weiss DJ.

Acta Biomater. 2020 Jan 15;102:231-246. doi: 10.1016/j.actbio.2019.11.029. Epub 2019 Nov 18.

PMID:
31751810
19.

Chemoenzymatic Synthesis of Glycosaminoglycans.

Zhang X, Lin L, Huang H, Linhardt RJ.

Acc Chem Res. 2019 Nov 12. doi: 10.1021/acs.accounts.9b00420. [Epub ahead of print]

PMID:
31714740
20.

Evaluating Heparin Products for Heparin-Induced Thrombocytopenia Using Surface Plasmon Resonance.

Zhang F, Datta P, Dordick JS, Linhardt RJ.

J Pharm Sci. 2020 Feb;109(2):975-980. doi: 10.1016/j.xphs.2019.10.040. Epub 2019 Nov 6.

PMID:
31705871
21.

3-O-Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake.

Zhao J, Zhu Y, Song X, Xiao Y, Su G, Liu X, Wang Z, Xu Y, Liu J, Eliezer D, Ramlall TF, Lippens G, Gibson J, Zhang F, Linhardt RJ, Wang L, Wang C.

Angew Chem Int Ed Engl. 2020 Jan 27;59(5):1818-1827. doi: 10.1002/anie.201913029. Epub 2019 Dec 10.

PMID:
31692167
22.

Structural Analysis of Urinary Glycosaminoglycans from Healthy Human Subjects.

Ha X, Sanderson P, Nesheiwat S, Lin L, Yu Y, Zhang F, Amster IJ, Linhardt RJ.

Glycobiology. 2019 Oct 16. pii: cwz088. doi: 10.1093/glycob/cwz088. [Epub ahead of print]

PMID:
31616929
23.

Rethinking the impact of RG-I mainly from fruits and vegetables on dietary health.

Wu D, Zheng J, Mao G, Hu W, Ye X, Linhardt RJ, Chen S.

Crit Rev Food Sci Nutr. 2019 Oct 14:1-23. doi: 10.1080/10408398.2019.1672037. [Epub ahead of print]

PMID:
31607142
24.

Storage stability studies on interesterified blend-based fast-frozen special fats for oxidative stability, crystallization characteristics and physical properties.

Zhu TW, Zhang X, Zong MH, Linhardt RJ, Wu H, Li B.

Food Chem. 2020 Feb 15;306:125563. doi: 10.1016/j.foodchem.2019.125563. Epub 2019 Oct 4.

PMID:
31606626
25.

Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly(ɛ-Caprolactone) Scaffolds.

Silva JC, Moura CS, Borrecho G, de Matos APA, da Silva CL, Cabral JMS, Bártolo PJ, Linhardt RJ, Ferreira FC.

Biotechnol J. 2020 Feb;15(2):e1900078. doi: 10.1002/biot.201900078. Epub 2019 Oct 21.

PMID:
31560160
26.

Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly.

Pawar NJ, Wang L, Higo T, Bhattacharya C, Kancharla PK, Zhang F, Baryal K, Huo CX, Liu J, Linhardt RJ, Huang X, Hsieh-Wilson LC.

Angew Chem Int Ed Engl. 2019 Dec 16;58(51):18577-18583. doi: 10.1002/anie.201908805. Epub 2019 Nov 6. Review.

PMID:
31553820
27.

Comparison of the Interactions of Different Growth Factors and Glycosaminoglycans.

Zhang F, Zheng L, Cheng S, Peng Y, Fu L, Zhang X, Linhardt RJ.

Molecules. 2019 Sep 16;24(18). pii: E3360. doi: 10.3390/molecules24183360.

28.

High-throughput method for in process monitoring of 3-O-sulfotransferase catalyzed sulfonation in bioengineered heparin synthesis.

Lin L, Yu Y, Zhang F, Zhang X, Linhardt RJ.

Anal Biochem. 2019 Dec 1;586:113419. doi: 10.1016/j.ab.2019.113419. Epub 2019 Sep 10.

PMID:
31518551
29.

Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.

Oshima K, Han X, Ouyang Y, El Masri R, Yang Y, Haeger SM, McMurtry SA, Lane TC, Davizon-Castillo P, Zhang F, Yue X, Vivès RR, Linhardt RJ, Schmidt EP.

Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L667-L677. doi: 10.1152/ajplung.00175.2019. Epub 2019 Aug 28.

PMID:
31461325
30.

Metabolic engineering of Bacillus megaterium for heparosan biosynthesis using Pasteurella multocida heparosan synthase, PmHS2.

Williams A, Gedeon KS, Vaidyanathan D, Yu Y, Collins CH, Dordick JS, Linhardt RJ, Koffas MAG.

Microb Cell Fact. 2019 Aug 12;18(1):132. doi: 10.1186/s12934-019-1187-9.

31.

Bottom-up analysis using liquid chromatography-Fourier transform mass spectrometry to characterize fucosylated chondroitin sulfates from sea cucumbers.

Yan L, Li L, Li J, Yu Y, Liu X, Ye X, Linhardt RJ, Chen S.

Glycobiology. 2019 Oct 21;29(11):755-764. doi: 10.1093/glycob/cwz057.

32.

Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation.

Hippensteel JA, Uchimido R, Tyler PD, Burke RC, Han X, Zhang F, McMurtry SA, Colbert JF, Lindsell CJ, Angus DC, Kellum JA, Yealy DM, Linhardt RJ, Shapiro NI, Schmidt EP.

Crit Care. 2019 Jul 23;23(1):259. doi: 10.1186/s13054-019-2534-2.

33.

Highly purified fucosylated chondroitin sulfate oligomers with selective intrinsic factor Xase complex inhibition.

Yan L, Wang D, Zhu M, Yu Y, Zhang F, Ye X, Linhardt RJ, Chen S.

Carbohydr Polym. 2019 Oct 15;222:115025. doi: 10.1016/j.carbpol.2019.115025. Epub 2019 Jun 27.

PMID:
31320079
34.

1D and 2D-HSQC NMR: Two Methods to Distinguish and Characterize Heparin From Different Animal and Tissue Sources.

Mauri L, Marinozzi M, Phatak N, Karfunkle M, St Ange K, Guerrini M, Keire DA, Linhardt RJ.

Front Med (Lausanne). 2019 Jun 27;6:142. doi: 10.3389/fmed.2019.00142. eCollection 2019.

35.

Bottom-up and top-down profiling of pentosan polysulfate.

Lin L, Yu Y, Zhang F, Xia K, Zhang X, Linhardt RJ.

Analyst. 2019 Aug 5;144(16):4781-4786. doi: 10.1039/c9an01006h.

PMID:
31287456
36.

Determination of cerebrospinal fluid leakage by selective deletion of transferrin glycoform using an immunochromatographic assay.

Oh J, Kwon SJ, Dordick JS, Sonstein WJ, Linhardt RJ, Kim MG.

Theranostics. 2019 May 31;9(14):4182-4191. doi: 10.7150/thno.34411. eCollection 2019.

37.

Interesterified blend-based and physical blend-based special fats: storage stability under fluctuating temperatures.

Zhu TW, Zhang X, Zong MH, Linhardt RJ, Li B, Wu H.

J Sci Food Agric. 2019 Nov;99(14):6219-6226. doi: 10.1002/jsfa.9894. Epub 2019 Aug 8.

PMID:
31250449
38.

Increased 3'-Phosphoadenosine-5'-phosphosulfate Levels in Engineered Escherichia coli Cell Lysate Facilitate the In Vitro Synthesis of Chondroitin Sulfate A.

Badri A, Williams A, Xia K, Linhardt RJ, Koffas MAG.

Biotechnol J. 2019 Sep;14(9):e1800436. doi: 10.1002/biot.201800436. Epub 2019 Jul 1.

PMID:
31180182
39.

Dose-dependent neuroprotective effect of oriental phyto-derived glycyrrhizin on experimental neuroterminal norepinephrine depletion in a rat brain model.

Ahmed-Farid OA, Haredy SA, Niazy RM, Linhardt RJ, Warda M.

Chem Biol Interact. 2019 Aug 1;308:279-287. doi: 10.1016/j.cbi.2019.05.045. Epub 2019 May 28.

PMID:
31150628
40.

Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei.

Yu Y, Williams A, Zhang X, Fu L, Xia K, Xu Y, Zhang F, Liu J, Koffas M, Linhardt RJ.

Glycobiology. 2019 Jul 19;29(8):572-581. doi: 10.1093/glycob/cwz039.

PMID:
31143933
41.

Systematic analysis of enoxaparins from different sources with online one- and two-dimensional chromatography.

Ouyang Y, Zhu M, Wang X, Yi L, Fareed J, Linhardt RJ, Zhang Z.

Analyst. 2019 Jun 21;144(12):3746-3755. doi: 10.1039/c9an00399a. Epub 2019 Apr 24.

PMID:
31016304
42.

Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions.

Zhang X, Han X, Xia K, Xu Y, Yang Y, Oshima K, Haeger SM, Perez MJ, McMurtry SA, Hippensteel JA, Ford JA, Herson PS, Liu J, Schmidt EP, Linhardt RJ.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9208-9213. doi: 10.1073/pnas.1902227116. Epub 2019 Apr 22.

43.

Comparison of Low-Molecular-Weight Heparins Prepared From Ovine Heparins With Enoxaparin.

Chen J, Yu Y, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Jin C, Jin Y, Yao Y, Xia K, Zhang F, Chen S, Ye X, Linhardt RJ.

Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619840701. doi: 10.1177/1076029619840701.

44.

A Molecular Hero Suit for In Vitro and In Vivo DNA Nanostructures.

Kizer ME, Linhardt RJ, Chandrasekaran AR, Wang X.

Small. 2019 Jun;15(26):e1805386. doi: 10.1002/smll.201805386. Epub 2019 Apr 15. Review.

PMID:
30985074
45.

Novel Cellulose-Halloysite Hemostatic Nanocomposite Fibers with a Dramatic Reduction in Human Plasma Coagulation Time.

Udangawa RN, Mikael PE, Mancinelli C, Chapman C, Willard CF, Simmons TJ, Linhardt RJ.

ACS Appl Mater Interfaces. 2019 May 1;11(17):15447-15456. doi: 10.1021/acsami.9b04615. Epub 2019 Apr 22.

PMID:
30977359
46.

Chemically modified polysaccharides: Synthesis, characterization, structure activity relationships of action.

Xu Y, Wu YJ, Sun PL, Zhang FM, Linhardt RJ, Zhang AQ.

Int J Biol Macromol. 2019 Jul 1;132:970-977. doi: 10.1016/j.ijbiomac.2019.03.213. Epub 2019 Apr 6. Review.

PMID:
30965077
47.

Glycosaminoglycans compositional analysis of Urodele axolotl (Ambystoma mexicanum) and Porcine Retina.

Kim SY, Kundu J, Williams A, Yandulskaya AS, Monaghan JR, Carrier RL, Linhardt RJ.

Glycoconj J. 2019 Apr;36(2):165-174. doi: 10.1007/s10719-019-09863-5. Epub 2019 Apr 8.

PMID:
30963354
48.

PBN11-8, a Cytotoxic Polypeptide Purified from Marine Bacillus, Suppresses Invasion and Migration of Human Hepatocellular Carcinoma Cells by Targeting Focal Adhesion Kinase Pathways.

Zheng L, Zhu X, Yang K, Zhu M, Farooqi AA, Kang D, Sun M, Xu Y, Lin X, Feng Y, Liang F, Zhang F, Linhardt RJ.

Polymers (Basel). 2018 Sep 19;10(9). pii: E1043. doi: 10.3390/polym10091043.

49.

Development of low molecular weight heparin by H2O2/ascorbic acid with ultrasonic power and its anti-metastasis property.

Shen X, Liu Z, Li J, Wu D, Zhu M, Yan L, Mao G, Ye X, Linhardt RJ, Chen S.

Int J Biol Macromol. 2019 Jul 15;133:101-109. doi: 10.1016/j.ijbiomac.2019.04.019. Epub 2019 Apr 4.

PMID:
30954594
50.

Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering.

Carvalho MS, Silva JC, Udangawa RN, Cabral JMS, Ferreira FC, da Silva CL, Linhardt RJ, Vashishth D.

Mater Sci Eng C Mater Biol Appl. 2019 Jun;99:479-490. doi: 10.1016/j.msec.2019.01.127. Epub 2019 Jan 30.

PMID:
30889723

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