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Items: 1 to 50 of 830

1.

Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure.

Arnold K, Xu Y, Sparkenbaugh EM, Li M, Han X, Zhang X, Xia K, Piegore M, Zhang F, Zhang X, Henderson M, Pagadala V, Su G, Tan L, Park PW, Stravitz RT, Key NS, Linhardt RJ, Pawlinski R, Xu D, Liu J.

Sci Transl Med. 2020 Mar 18;12(535). pii: eaav8075. doi: 10.1126/scitranslmed.aav8075.

PMID:
32188725
2.

Biotechnology progress for removal of indoor gaseous formaldehyde.

Shao Y, Wang Y, Zhao R, Chen J, Zhang F, Linhardt RJ, Zhong W.

Appl Microbiol Biotechnol. 2020 Mar 14. doi: 10.1007/s00253-020-10514-1. [Epub ahead of print] Review.

PMID:
32172323
3.

Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells.

Carvalho MS, Silva JC, Hoff CM, Cabral JMS, Linhardt RJ, da Silva CL, Vashishth D.

J Cell Physiol. 2020 Mar 11. doi: 10.1002/jcp.29653. [Epub ahead of print]

PMID:
32162324
4.

Digestibility of squash polysaccharide under simulated salivary, gastric and intestinal conditions and its impact on short-chain fatty acid production in type-2 diabetic rats.

Liang L, Liu G, Zhang F, Li Q, Linhardt RJ.

Carbohydr Polym. 2020 May 1;235:115904. doi: 10.1016/j.carbpol.2020.115904. Epub 2020 Jan 24.

PMID:
32122473
5.

Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin sulfate supplementation.

Moura CS, Silva JC, Faria S, Fernandes PR, da Silva CL, Cabral JMS, Linhardt R, Bártolo PJ, Ferreira FC.

J Biosci Bioeng. 2020 Feb 25. pii: S1389-1723(19)30824-2. doi: 10.1016/j.jbiosc.2020.01.004. [Epub ahead of print]

PMID:
32107152
6.

Extraction Methods Affect the Structure of Goji (Lycium barbarum) Polysaccharides.

Zhou S, Rahman A, Li J, Wei C, Chen J, Linhardt RJ, Ye X, Chen S.

Molecules. 2020 Feb 19;25(4). pii: E936. doi: 10.3390/molecules25040936.

7.

Chemical, enzymatic and biological synthesis of hyaluronic acids.

Li J, Qiao M, Ji Y, Lin L, Zhang X, Linhardt RJ.

Int J Biol Macromol. 2020 Feb 20;152:199-206. doi: 10.1016/j.ijbiomac.2020.02.214. [Epub ahead of print] Review.

PMID:
32088231
8.

Glycosaminoglycan remodeling during chondrogenic differentiation of human bone marrow-/synovial-derived mesenchymal stem/stromal cells under normoxia and hypoxia.

Silva JC, Han X, Silva TP, Xia K, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ.

Glycoconj J. 2020 Feb 21. doi: 10.1007/s10719-020-09911-5. [Epub ahead of print]

PMID:
32086666
9.

Autophagic degradation of HAS2 in endothelial cells: A novel mechanism to regulate angiogenesis.

Chen CG, Gubbiotti MA, Kapoor A, Han X, Yu Y, Linhardt RJ, Iozzo RV.

Matrix Biol. 2020 Feb 19. pii: S0945-053X(20)30011-1. doi: 10.1016/j.matbio.2020.02.001. [Epub ahead of print]

PMID:
32084457
10.

Mass spectrometric evidence for the mechanism of free-radical depolymerization of various types of glycosaminoglycans.

Zhang N, Li G, Li S, Cai C, Zhang F, Linhardt RJ, Yu G.

Carbohydr Polym. 2020 Apr 1;233:115847. doi: 10.1016/j.carbpol.2020.115847. Epub 2020 Jan 10.

PMID:
32059898
11.

Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review.

Lu J, He R, Sun P, Zhang F, Linhardt RJ, Zhang A.

Int J Biol Macromol. 2020 Feb 6;150:765-774. doi: 10.1016/j.ijbiomac.2020.02.035. [Epub ahead of print] Review.

PMID:
32035956
12.

Structural analysis of a novel sulfated galacto-fuco-xylo-glucurono-mannan from Sargassum fusiforme and its anti-lung cancer activity.

Jin W, Tang H, Zhang J, Wei B, Sun J, Zhang W, Zhang F, Wang H, Linhardt RJ, Zhong W.

Int J Biol Macromol. 2020 Apr 15;149:450-458. doi: 10.1016/j.ijbiomac.2020.01.275. Epub 2020 Jan 28.

PMID:
32004605
13.

Encapsulation of phycocyanin by prebiotics and polysaccharides-based electrospun fibers and improved colon cancer prevention effects.

Wen Y, Wen P, Hu TG, Linhardt RJ, Zong MH, Wu H, Chen ZY.

Int J Biol Macromol. 2020 Apr 15;149:672-681. doi: 10.1016/j.ijbiomac.2020.01.189. Epub 2020 Jan 22.

PMID:
31981665
14.

Comprehensive Glycomic Analysis Reveals That Human Serum Albumin Glycation Specifically Affects the Pharmacokinetics and Efficacy of Different Anticoagulant Drugs in Diabetes.

Qiu H, Jin L, Chen J, Shi M, Shi F, Wang M, Li D, Xu X, Su X, Yin X, Li W, Zhou X, Linhardt RJ, Wang Z, Chi L, Zhang Q.

Diabetes. 2020 Apr;69(4):760-770. doi: 10.2337/db19-0738. Epub 2020 Jan 23.

PMID:
31974145
15.

Non-anticoagulant Heparin as a Pre-exposure Prophylaxis Prevents Lyme Disease Infection.

Lin YP, Yu Y, Marcinkiewicz AL, Lederman P, Hart TM, Zhang F, Linhardt RJ.

ACS Infect Dis. 2020 Mar 13;6(3):503-514. doi: 10.1021/acsinfecdis.9b00425. Epub 2020 Jan 30.

PMID:
31961652
16.

Extracellular matrix decorated polycaprolactone scaffolds for improved mesenchymal stem/stromal cell osteogenesis towards a patient-tailored bone tissue engineering approach.

Silva JC, Carvalho MS, Udangawa RN, Moura CS, Cabral JMS, L da Silva C, Ferreira FC, Vashishth D, Linhardt RJ.

J Biomed Mater Res B Appl Biomater. 2020 Jan 9. doi: 10.1002/jbm.b.34554. [Epub ahead of print]

PMID:
31916699
17.

Site-selective reactions for the synthesis of glycoconjugates in polysaccharide vaccine development.

Lin L, Qiao M, Zhang X, Linhardt RJ.

Carbohydr Polym. 2020 Feb 15;230:115643. doi: 10.1016/j.carbpol.2019.115643. Epub 2019 Nov 19. Review.

PMID:
31887910
18.

Regulation of PTP1B activation through disruption of redox-complex formation.

Londhe AD, Bergeron A, Curley SM, Zhang F, Rivera KD, Kannan A, Coulis G, Rizvi SHM, Kim SJ, Pappin DJ, Tonks NK, Linhardt RJ, Boivin B.

Nat Chem Biol. 2020 Feb;16(2):122-125. doi: 10.1038/s41589-019-0433-0. Epub 2019 Dec 23.

PMID:
31873221
19.

A novel route for double-layered encapsulation of probiotics with improved viability under adverse conditions.

Feng K, Huang RM, Wu RQ, Wei YS, Zong MH, Linhardt RJ, Wu H.

Food Chem. 2020 Apr 25;310:125977. doi: 10.1016/j.foodchem.2019.125977. Epub 2019 Dec 4.

PMID:
31837527
20.

Interactions between Sclerostin and Glycosaminoglycans.

Zhang F, Zhao J, Liu X, Linhardt RJ.

Glycoconj J. 2020 Feb;37(1):119-128. doi: 10.1007/s10719-019-09900-3. Epub 2019 Dec 11.

PMID:
31828567
21.

Urinary metabolomics analysis reveals the anti-diabetic effect of stachyose in high-fat diet/streptozotocin-induced type 2 diabetic rats.

Liang L, Liu G, Yu G, Zhang F, Linhardt RJ, Li Q.

Carbohydr Polym. 2020 Feb 1;229:115534. doi: 10.1016/j.carbpol.2019.115534. Epub 2019 Oct 31.

PMID:
31826396
22.
23.

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition.

Kwon PS, Ren S, Kwon SJ, Kizer ME, Kuo L, Xie M, Zhu D, Zhou F, Zhang F, Kim D, Fraser K, Kramer LD, Seeman NC, Dordick JS, Linhardt RJ, Chao J, Wang X.

Nat Chem. 2020 Jan;12(1):26-35. doi: 10.1038/s41557-019-0369-8. Epub 2019 Nov 25.

PMID:
31767992
24.

Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering.

Silva JC, Udangawa RN, Chen J, Mancinelli CD, Garrudo FFF, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ.

Mater Sci Eng C Mater Biol Appl. 2020 Feb;107:110291. doi: 10.1016/j.msec.2019.110291. Epub 2019 Oct 8.

PMID:
31761240
25.

Extraction, structure and bioactivities of the polysaccharides from Pleurotus eryngii: A review.

Zhang B, Li Y, Zhang F, Linhardt RJ, Zeng G, Zhang A.

Int J Biol Macromol. 2019 Nov 20. pii: S0141-8130(19)33821-8. doi: 10.1016/j.ijbiomac.2019.10.144. [Epub ahead of print] Review.

PMID:
31759001
26.

A novel laminin-binding protein mediates microbial-endothelial cell interactions and facilitates dissemination of Lyme disease pathogens.

Bista S, Singh P, Bernard Q, Yang X, Hart T, Lin YP, Kitsou C, Singh Rana V, Zhang F, Linhardt RJ, Zhnag K, Akins DR, Hritzo L, Kim Y, Grab DJ, Dumler JS, Pal U.

J Infect Dis. 2019 Nov 23. pii: jiz626. doi: 10.1093/infdis/jiz626. [Epub ahead of print]

PMID:
31758693
27.

Functional role of glycosaminoglycans in decellularized lung extracellular matrix.

Uhl FE, Zhang F, Pouliot RA, Uriarte JJ, Rolandsson Enes S, Han X, Ouyang Y, Xia K, Westergren-Thorsson G, Malmström A, Hallgren O, Linhardt RJ, Weiss DJ.

Acta Biomater. 2020 Jan 15;102:231-246. doi: 10.1016/j.actbio.2019.11.029. Epub 2019 Nov 18.

PMID:
31751810
28.

Chemoenzymatic Synthesis of Glycosaminoglycans.

Zhang X, Lin L, Huang H, Linhardt RJ.

Acc Chem Res. 2020 Feb 18;53(2):335-346. doi: 10.1021/acs.accounts.9b00420. Epub 2019 Nov 12.

PMID:
31714740
29.

Evaluating Heparin Products for Heparin-Induced Thrombocytopenia Using Surface Plasmon Resonance.

Zhang F, Datta P, Dordick JS, Linhardt RJ.

J Pharm Sci. 2020 Feb;109(2):975-980. doi: 10.1016/j.xphs.2019.10.040. Epub 2019 Nov 6.

PMID:
31705871
30.

3-O-Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake.

Zhao J, Zhu Y, Song X, Xiao Y, Su G, Liu X, Wang Z, Xu Y, Liu J, Eliezer D, Ramlall TF, Lippens G, Gibson J, Zhang F, Linhardt RJ, Wang L, Wang C.

Angew Chem Int Ed Engl. 2020 Jan 27;59(5):1818-1827. doi: 10.1002/anie.201913029. Epub 2019 Dec 10.

PMID:
31692167
31.

Structural analysis of urinary glycosaminoglycans from healthy human subjects.

Han X, Sanderson P, Nesheiwat S, Lin L, Yu Y, Zhang F, Amster IJ, Linhardt RJ.

Glycobiology. 2020 Feb 19;30(3):143-151. doi: 10.1093/glycob/cwz088.

PMID:
31616929
32.

Rethinking the impact of RG-I mainly from fruits and vegetables on dietary health.

Wu D, Zheng J, Mao G, Hu W, Ye X, Linhardt RJ, Chen S.

Crit Rev Food Sci Nutr. 2019 Oct 14:1-23. doi: 10.1080/10408398.2019.1672037. [Epub ahead of print]

PMID:
31607142
33.

Storage stability studies on interesterified blend-based fast-frozen special fats for oxidative stability, crystallization characteristics and physical properties.

Zhu TW, Zhang X, Zong MH, Linhardt RJ, Wu H, Li B.

Food Chem. 2020 Feb 15;306:125563. doi: 10.1016/j.foodchem.2019.125563. Epub 2019 Oct 4.

PMID:
31606626
34.

Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly(ɛ-Caprolactone) Scaffolds.

Silva JC, Moura CS, Borrecho G, de Matos APA, da Silva CL, Cabral JMS, Bártolo PJ, Linhardt RJ, Ferreira FC.

Biotechnol J. 2020 Feb;15(2):e1900078. doi: 10.1002/biot.201900078. Epub 2019 Oct 21.

PMID:
31560160
35.

Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly.

Pawar NJ, Wang L, Higo T, Bhattacharya C, Kancharla PK, Zhang F, Baryal K, Huo CX, Liu J, Linhardt RJ, Huang X, Hsieh-Wilson LC.

Angew Chem Int Ed Engl. 2019 Dec 16;58(51):18577-18583. doi: 10.1002/anie.201908805. Epub 2019 Nov 6. Review.

PMID:
31553820
36.

Comparison of the Interactions of Different Growth Factors and Glycosaminoglycans.

Zhang F, Zheng L, Cheng S, Peng Y, Fu L, Zhang X, Linhardt RJ.

Molecules. 2019 Sep 16;24(18). pii: E3360. doi: 10.3390/molecules24183360.

37.

High-throughput method for in process monitoring of 3-O-sulfotransferase catalyzed sulfonation in bioengineered heparin synthesis.

Lin L, Yu Y, Zhang F, Zhang X, Linhardt RJ.

Anal Biochem. 2019 Dec 1;586:113419. doi: 10.1016/j.ab.2019.113419. Epub 2019 Sep 10.

PMID:
31518551
38.

Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.

Oshima K, Han X, Ouyang Y, El Masri R, Yang Y, Haeger SM, McMurtry SA, Lane TC, Davizon-Castillo P, Zhang F, Yue X, Vivès RR, Linhardt RJ, Schmidt EP.

Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L667-L677. doi: 10.1152/ajplung.00175.2019. Epub 2019 Aug 28.

PMID:
31461325
39.

Metabolic engineering of Bacillus megaterium for heparosan biosynthesis using Pasteurella multocida heparosan synthase, PmHS2.

Williams A, Gedeon KS, Vaidyanathan D, Yu Y, Collins CH, Dordick JS, Linhardt RJ, Koffas MAG.

Microb Cell Fact. 2019 Aug 12;18(1):132. doi: 10.1186/s12934-019-1187-9.

40.

Bottom-up analysis using liquid chromatography-Fourier transform mass spectrometry to characterize fucosylated chondroitin sulfates from sea cucumbers.

Yan L, Li L, Li J, Yu Y, Liu X, Ye X, Linhardt RJ, Chen S.

Glycobiology. 2019 Oct 21;29(11):755-764. doi: 10.1093/glycob/cwz057.

41.

Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation.

Hippensteel JA, Uchimido R, Tyler PD, Burke RC, Han X, Zhang F, McMurtry SA, Colbert JF, Lindsell CJ, Angus DC, Kellum JA, Yealy DM, Linhardt RJ, Shapiro NI, Schmidt EP.

Crit Care. 2019 Jul 23;23(1):259. doi: 10.1186/s13054-019-2534-2.

42.

Highly purified fucosylated chondroitin sulfate oligomers with selective intrinsic factor Xase complex inhibition.

Yan L, Wang D, Zhu M, Yu Y, Zhang F, Ye X, Linhardt RJ, Chen S.

Carbohydr Polym. 2019 Oct 15;222:115025. doi: 10.1016/j.carbpol.2019.115025. Epub 2019 Jun 27.

PMID:
31320079
43.

1D and 2D-HSQC NMR: Two Methods to Distinguish and Characterize Heparin From Different Animal and Tissue Sources.

Mauri L, Marinozzi M, Phatak N, Karfunkle M, St Ange K, Guerrini M, Keire DA, Linhardt RJ.

Front Med (Lausanne). 2019 Jun 27;6:142. doi: 10.3389/fmed.2019.00142. eCollection 2019.

44.

Glycan Markers of Human Stem Cells Assigned with Beam Search Arrays.

Wu N, Silva LM, Liu Y, Zhang Y, Gao C, Zhang F, Fu L, Peng Y, Linhardt R, Kawasaki T, Mulloy B, Chai W, Feizi T.

Mol Cell Proteomics. 2019 Oct;18(10):1981-2002. doi: 10.1074/mcp.RA119.001309. Epub 2019 Jul 15.

45.

Bottom-up and top-down profiling of pentosan polysulfate.

Lin L, Yu Y, Zhang F, Xia K, Zhang X, Linhardt RJ.

Analyst. 2019 Aug 5;144(16):4781-4786. doi: 10.1039/c9an01006h.

PMID:
31287456
46.

Determination of cerebrospinal fluid leakage by selective deletion of transferrin glycoform using an immunochromatographic assay.

Oh J, Kwon SJ, Dordick JS, Sonstein WJ, Linhardt RJ, Kim MG.

Theranostics. 2019 May 31;9(14):4182-4191. doi: 10.7150/thno.34411. eCollection 2019.

47.

Interesterified blend-based and physical blend-based special fats: storage stability under fluctuating temperatures.

Zhu TW, Zhang X, Zong MH, Linhardt RJ, Li B, Wu H.

J Sci Food Agric. 2019 Nov;99(14):6219-6226. doi: 10.1002/jsfa.9894. Epub 2019 Aug 8.

PMID:
31250449
48.

Increased 3'-Phosphoadenosine-5'-phosphosulfate Levels in Engineered Escherichia coli Cell Lysate Facilitate the In Vitro Synthesis of Chondroitin Sulfate A.

Badri A, Williams A, Xia K, Linhardt RJ, Koffas MAG.

Biotechnol J. 2019 Sep;14(9):e1800436. doi: 10.1002/biot.201800436. Epub 2019 Jul 1.

PMID:
31180182
49.

Dose-dependent neuroprotective effect of oriental phyto-derived glycyrrhizin on experimental neuroterminal norepinephrine depletion in a rat brain model.

Ahmed-Farid OA, Haredy SA, Niazy RM, Linhardt RJ, Warda M.

Chem Biol Interact. 2019 Aug 1;308:279-287. doi: 10.1016/j.cbi.2019.05.045. Epub 2019 May 28.

PMID:
31150628
50.

Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei.

Yu Y, Williams A, Zhang X, Fu L, Xia K, Xu Y, Zhang F, Liu J, Koffas M, Linhardt RJ.

Glycobiology. 2019 Jul 19;29(8):572-581. doi: 10.1093/glycob/cwz039.

PMID:
31143933

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