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Items: 1 to 50 of 149

1.

Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling.

Wong RW, Lingwood CA, Ostrowski MA, Cabral T, Cochrane A.

Sci Rep. 2018 Jan 16;8(1):850. doi: 10.1038/s41598-018-19298-x.

2.

Glycosphingolipid storage in Fabry mice extends beyond globotriaosylceramide and is affected by ABCB1 depletion.

Kamani MA, Provençal P, Boutin M, Pacienza N, Fan X, Novak A, Huang TC, Binnington B, Au BC, Auray-Blais C, Lingwood CA, Medin JA.

Future Sci OA. 2016 Oct 13;2(4):FSO147. doi: 10.4155/fsoa-2016-0027. eCollection 2016 Dec.

3.

Inhibition of Rab prenylation by statins induces cellular glycosphingolipid remodeling.

Binnington B, Nguyen L, Kamani M, Hossain D, Marks DL, Budani M, Lingwood CA.

Glycobiology. 2016 Feb;26(2):166-80. doi: 10.1093/glycob/cwv084. Epub 2015 Sep 24.

4.

Cholesterol masks membrane glycosphingolipid tumor-associated antigens to reduce their immunodetection in human cancer biopsies.

Novak A, Binnington B, Ngan B, Chadwick K, Fleshner N, Lingwood CA.

Glycobiology. 2013 Nov;23(11):1230-9. doi: 10.1093/glycob/cwt059. Epub 2013 Jul 31.

PMID:
23906628
5.

CD4(+) T-cells are unable to express the HIV natural resistance factor globotriosylceramide.

Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR.

AIDS. 2013 Mar 27;27(6):1029-32. doi: 10.1097/QAD.0b013e32835f1ec5.

PMID:
23380967
6.

Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane.

Gerl MJ, Sampaio JL, Urban S, Kalvodova L, Verbavatz JM, Binnington B, Lindemann D, Lingwood CA, Shevchenko A, Schroeder C, Simons K.

J Cell Biol. 2012 Jan 23;196(2):213-21. doi: 10.1083/jcb.201108175. Epub 2012 Jan 16.

7.

Comparison of detection methods for cell surface globotriaosylceramide.

Kim M, Binnington B, Sakac D, Fernandes KR, Shi SP, Lingwood CA, Branch DR.

J Immunol Methods. 2011 Aug 31;371(1-2):48-60. doi: 10.1016/j.jim.2011.06.014. Epub 2011 Jun 24.

PMID:
21726561
8.

Glycosphingolipid functions.

Lingwood CA.

Cold Spring Harb Perspect Biol. 2011 Jul 1;3(7). pii: a004788. doi: 10.1101/cshperspect.a004788. Review. Erratum in: Cold Spring Harb Perspect Biol. 2011 Sep;3(9):a011874.

9.

The role of glycosphingolipids in HIV/AIDS.

Lingwood CA, Branch DR.

Discov Med. 2011 Apr;11(59):303-13. Review.

10.

Cholesterol modulates glycolipid conformation and receptor activity.

Lingwood D, Binnington B, Róg T, Vattulainen I, Grzybek M, Coskun U, Lingwood CA, Simons K.

Nat Chem Biol. 2011 May;7(5):260-2. doi: 10.1038/nchembio.551. Epub 2011 Apr 3.

PMID:
21460830
11.

A major fraction of glycosphingolipids in model and cellular cholesterol-containing membranes is undetectable by their binding proteins.

Mahfoud R, Manis A, Binnington B, Ackerley C, Lingwood CA.

J Biol Chem. 2010 Nov 12;285(46):36049-59. doi: 10.1074/jbc.M110.110189. Epub 2010 Aug 17.

12.

A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms.

Harrison AL, Olsson ML, Jones RB, Ramkumar S, Sakac D, Binnington B, Henry S, Lingwood CA, Branch DR.

Glycoconj J. 2010 Jul;27(5):515-24. doi: 10.1007/s10719-010-9297-y. Epub 2010 Jun 26.

PMID:
20582467
13.

Globotriaosyl ceramide receptor function - where membrane structure and pathology intersect.

Lingwood CA, Binnington B, Manis A, Branch DR.

FEBS Lett. 2010 May 3;584(9):1879-86. doi: 10.1016/j.febslet.2009.11.089. Epub 2009 Dec 2. Review.

14.

New aspects of the regulation of glycosphingolipid receptor function.

Lingwood CA, Manis A, Mahfoud R, Khan F, Binnington B, Mylvaganam M.

Chem Phys Lipids. 2010 Jan;163(1):27-35. doi: 10.1016/j.chemphyslip.2009.09.001. Review.

PMID:
19781539
15.

A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation.

Park HJ, Mylvaganum M, McPherson A, Fewell SW, Brodsky JL, Lingwood CA.

Chem Biol. 2009 Apr 24;16(4):461-70. doi: 10.1016/j.chembiol.2009.02.014.

16.

Detergent-resistant globotriaosyl ceramide may define verotoxin/glomeruli-restricted hemolytic uremic syndrome pathology.

Khan F, Proulx F, Lingwood CA.

Kidney Int. 2009 Jun;75(11):1209-1216. doi: 10.1038/ki.2009.7. Epub 2009 Feb 11.

17.

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.

Wright CM, Seguin SP, Fewell SW, Zhang H, Ishwad C, Vats A, Lingwood CA, Wipf P, Fanning E, Pipas JM, Brodsky JL.

Virus Res. 2009 Apr;141(1):71-80. doi: 10.1016/j.virusres.2008.12.018. Epub 2009 Feb 4.

18.

Oxidation of the primary hydroxyl group of galactose of galactaosyl ceramide analogue by chemical method-precursors for the synthesis of labeled conjugates.

Yonekawa S, Lingwood CA, Mylvaganam M.

Carbohydr Res. 2009 Mar 10;344(4):501-6. doi: 10.1016/j.carres.2008.12.002. Epub 2008 Dec 11.

PMID:
19144327
19.

The human P(k) histo-blood group antigen provides protection against HIV-1 infection.

Lund N, Olsson ML, Ramkumar S, Sakac D, Yahalom V, Levene C, Hellberg A, Ma XZ, Binnington B, Jung D, Lingwood CA, Branch DR.

Blood. 2009 May 14;113(20):4980-91. doi: 10.1182/blood-2008-03-143396. Epub 2009 Jan 12.

PMID:
19139081
20.

Induction of HIV-1 resistance: cell susceptibility to infection is an inverse function of globotriaosyl ceramide levels.

Ramkumar S, Sakac D, Binnington B, Branch DR, Lingwood CA.

Glycobiology. 2009 Jan;19(1):76-82. doi: 10.1093/glycob/cwn106. Epub 2008 Oct 8.

PMID:
18842961
21.

Fatty acid-dependent globotriaosyl ceramide receptor function in detergent resistant model membranes.

Mahfoud R, Manis A, Lingwood CA.

J Lipid Res. 2009 Sep;50(9):1744-55. doi: 10.1194/jlr.M800385-JLR200. Epub 2008 Aug 20.

22.

Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein.

Fujii J, Wood K, Matsuda F, Carneiro-Filho BA, Schlegel KH, Yutsudo T, Binnington-Boyd B, Lingwood CA, Obata F, Kim KS, Yoshida S, Obrig T.

Infect Immun. 2008 Aug;76(8):3679-89. doi: 10.1128/IAI.01581-07. Epub 2008 Jun 9.

23.

The medium is the message: glycosphingolipids and their soluble analogues.

De Rosa M, Park HJ, Mylvaganum M, Binnington B, Lund N, Branch DR, Lingwood CA.

Biochim Biophys Acta. 2008 Mar;1780(3):347-52. Epub 2007 Nov 4. Review.

PMID:
18022400
24.

Membrane cytosolic translocation of verotoxin A1 subunit in target cells.

Tam PJ, Lingwood CA.

Microbiology. 2007 Aug;153(Pt 8):2700-10.

PMID:
17660434
25.

Laboratory and clinical Pseudomonas aeruginosa strains do not bind glycosphingolipids in vitro or during type IV pili-mediated initial host cell attachment.

Emam A, Yu AR, Park HJ, Mahfoud R, Kus J, Burrows LL, Lingwood CA.

Microbiology. 2006 Sep;152(Pt 9):2789-99.

PMID:
16946273
26.

A novel soluble mimic of the glycolipid, globotriaosyl ceramide inhibits HIV infection.

Lund N, Branch DR, Mylvaganam M, Chark D, Ma XZ, Sakac D, Binnington B, Fantini J, Puri A, Blumenthal R, Lingwood CA.

AIDS. 2006 Feb 14;20(3):333-43.

PMID:
16439866
27.

Lack of susceptibility of cells from patients with Fabry disease to productive infection with R5 human immunodeficiency virus.

Lund N, Branch DR, Sakac D, Lingwood CA, Siatskas C, Robinson CJ, Brady RO, Medin JA.

AIDS. 2005 Sep 23;19(14):1543-6.

PMID:
16135910
28.

Brefeldin A and filipin distinguish two globotriaosyl ceramide/verotoxin-1 intracellular trafficking pathways involved in Vero cell cytotoxicity.

Khine AA, Tam P, Nutikka A, Lingwood CA.

Glycobiology. 2004 Aug;14(8):701-12. Epub 2004 Apr 21.

PMID:
15102715
29.
30.

Lipid modulation of glycosphingolipid (GSL) receptors: soluble GSL mimics provide new probes of GSL receptor function.

Lingwood CA, Mylvaganam M.

Methods Enzymol. 2003;363:264-83. No abstract available.

PMID:
14579581
31.

Verotoxin 1 binding to intestinal crypt epithelial cells results in localization to lysosomes and abrogation of toxicity.

Hoey DE, Sharp L, Currie C, Lingwood CA, Gally DL, Smith DG.

Cell Microbiol. 2003 Feb;5(2):85-97.

PMID:
12580945
32.

Induction by sphingomyelinase of shiga toxin receptor and shiga toxin 2 sensitivity in human microvascular endothelial cells.

Obrig TG, Seaner RM, Bentz M, Lingwood CA, Boyd B, Smith A, Narrow W.

Infect Immun. 2003 Feb;71(2):845-9.

33.

Methods for the identification of host receptors for Shiga toxin.

Nutikka A, Binnington-Boyd B, Lingwood CA.

Methods Mol Med. 2003;73:197-208. Review. No abstract available.

PMID:
12375430
34.

Methods for the purification of Shiga toxin 1.

Nutikka A, Binnington-Boyd B, Lingwood CA.

Methods Mol Med. 2003;73:187-95. Review. No abstract available.

PMID:
12375429
35.

Shiga toxin receptor glycolipid binding. Pathology and utility.

Lingwood CA.

Methods Mol Med. 2003;73:165-86. Review. No abstract available.

PMID:
12375428
36.

Effect of globotriaosyl ceramide fatty acid alpha-hydroxylation on the binding by verotoxin 1 and verotoxin 2.

Binnington B, Lingwood D, Nutikka A, Lingwood CA.

Neurochem Res. 2002 Aug;27(7-8):807-13.

PMID:
12374217
38.

Interaction of the verotoxin 1B subunit with soluble aminodeoxy analogues of globotriaosyl ceramides.

Mylvaganam M, Hansen HC, Binnington B, Magnusson G, Nyholm PG, Lingwood CA.

Biochem J. 2002 Dec 15;368(Pt 3):769-76.

39.

Differential tissue targeting and pathogenesis of verotoxins 1 and 2 in the mouse animal model.

Rutjes NW, Binnington BA, Smith CR, Maloney MD, Lingwood CA.

Kidney Int. 2002 Sep;62(3):832-45.

40.

Expression of receptors for verotoxin 1 from Escherichia coli O157 on bovine intestinal epithelium.

Hoey DE, Currie C, Else RW, Nutikka A, Lingwood CA, Gally DL, Smith DG.

J Med Microbiol. 2002 Feb;51(2):143-9.

PMID:
11865842
41.

Induction of epithelial cell death including apoptosis by enteropathogenic Escherichia coli expressing bundle-forming pili.

Abul-Milh M, Wu Y, Lau B, Lingwood CA, Barnett Foster D.

Infect Immun. 2001 Dec;69(12):7356-64.

42.

In vitro binding of Helicobacter pylori to monohexosylceramides.

Abul-Milh M, Barnett Foster D, Lingwood CA.

Glycoconj J. 2001 Mar;18(3):253-60.

PMID:
11602809
43.

Enteropathogenic Escherichia coli virulence factor bundle-forming pilus has a binding specificity for phosphatidylethanolamine.

Khursigara C, Abul-Milh M, Lau B, Girón JA, Lingwood CA, Barnett Foster DE.

Infect Immun. 2001 Nov;69(11):6573-9.

45.

Hsp70s contain a specific sulfogalactolipid binding site. Differential aglycone influence on sulfogalactosyl ceramide binding by recombinant prokaryotic and eukaryotic hsp70 family members.

Mamelak D, Mylvaganam M, Whetstone H, Hartmann E, Lennarz W, Wyrick PB, Raulston J, Han H, Hoffman P, Lingwood CA.

Biochemistry. 2001 Mar 27;40(12):3572-82.

PMID:
11297423
46.
47.

Globotriaosyl ceramide modulates interferon-alpha-induced growth inhibition and CD19 expression in Burkitt's lymphoma cells.

Maloney MD, Binnington-Boyd B, Lingwood CA.

Glycoconj J. 1999 Dec;16(12):821-8.

PMID:
11133022
48.
49.

Analysis of interactions between glycosphingolipids and microbial toxins.

Lingwood CA, Boyd B, Nutikka A.

Methods Enzymol. 2000;312:459-73. No abstract available.

PMID:
11070894
50.

Verotoxin targets lymphoma infiltrates of patients with post-transplant lymphoproliferative disease.

Arbus GS, Grisaru S, Segal O, Dosch M, Pop M, Lala P, Nutikka A, Lingwood CA.

Leuk Res. 2000 Oct;24(10):857-64.

PMID:
10996204

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