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Items: 1 to 50 of 200

1.

Author Correction: Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling.

Wong RW, Lingwood CA, Ostrowski MA, Cabral T, Cochrane A.

Sci Rep. 2019 Dec 4;9(1):18656. doi: 10.1038/s41598-019-54732-8.

2.

Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling.

Wong RW, Lingwood CA, Ostrowski MA, Cabral T, Cochrane A.

Sci Rep. 2018 Jan 16;8(1):850. doi: 10.1038/s41598-018-19298-x. Erratum in: Sci Rep. 2019 Dec 4;9(1):18656.

3.

Glycosphingolipid storage in Fabry mice extends beyond globotriaosylceramide and is affected by ABCB1 depletion.

Kamani MA, Provençal P, Boutin M, Pacienza N, Fan X, Novak A, Huang TC, Binnington B, Au BC, Auray-Blais C, Lingwood CA, Medin JA.

Future Sci OA. 2016 Oct 13;2(4):FSO147. doi: 10.4155/fsoa-2016-0027. eCollection 2016 Dec.

4.

Endoplasmic Reticulum-Targeted Subunit Toxins Provide a New Approach to Rescue Misfolded Mutant Proteins and Revert Cell Models of Genetic Diseases.

Adnan H, Zhang Z, Park HJ, Tailor C, Che C, Kamani M, Spitalny G, Binnington B, Lingwood C.

PLoS One. 2016 Dec 9;11(12):e0166948. doi: 10.1371/journal.pone.0166948. eCollection 2016.

5.

Suppression of Adenovirus Replication by Cardiotonic Steroids.

Grosso F, Stoilov P, Lingwood C, Brown M, Cochrane A.

J Virol. 2017 Jan 18;91(3). pii: e01623-16. doi: 10.1128/JVI.01623-16. Print 2017 Feb 1.

6.

Synthesis of a novel photoactivatable glucosylceramide cross-linker.

Budani M, Mylvaganam M, Binnington B, Lingwood C.

J Lipid Res. 2016 Sep;57(9):1728-36. doi: 10.1194/jlr.D069609. Epub 2016 Jul 13.

7.

Inhibition of Rab prenylation by statins induces cellular glycosphingolipid remodeling.

Binnington B, Nguyen L, Kamani M, Hossain D, Marks DL, Budani M, Lingwood CA.

Glycobiology. 2016 Feb;26(2):166-80. doi: 10.1093/glycob/cwv084. Epub 2015 Sep 24.

8.

Cholesterol masks membrane glycosphingolipid tumor-associated antigens to reduce their immunodetection in human cancer biopsies.

Novak A, Binnington B, Ngan B, Chadwick K, Fleshner N, Lingwood CA.

Glycobiology. 2013 Nov;23(11):1230-9. doi: 10.1093/glycob/cwt059. Epub 2013 Jul 31.

PMID:
23906628
9.

CD4(+) T-cells are unable to express the HIV natural resistance factor globotriosylceramide.

Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR.

AIDS. 2013 Mar 27;27(6):1029-32. doi: 10.1097/QAD.0b013e32835f1ec5.

PMID:
23380967
10.

Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro.

Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C.

Toxins (Basel). 2012 Dec 14;4(12):1517-34. doi: 10.3390/toxins4121517.

11.

Structure-dependent pseudoreceptor intracellular traffic of adamantyl globotriaosyl ceramide mimics.

Saito M, Mylvaganum M, Tam P, Novak A, Binnington B, Lingwood C.

J Biol Chem. 2012 May 11;287(20):16073-87. doi: 10.1074/jbc.M111.318196. Epub 2012 Mar 14.

12.

Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane.

Gerl MJ, Sampaio JL, Urban S, Kalvodova L, Verbavatz JM, Binnington B, Lindemann D, Lingwood CA, Shevchenko A, Schroeder C, Simons K.

J Cell Biol. 2012 Jan 23;196(2):213-21. doi: 10.1083/jcb.201108175. Epub 2012 Jan 16.

13.

Comparison of detection methods for cell surface globotriaosylceramide.

Kim M, Binnington B, Sakac D, Fernandes KR, Shi SP, Lingwood CA, Branch DR.

J Immunol Methods. 2011 Aug 31;371(1-2):48-60. doi: 10.1016/j.jim.2011.06.014. Epub 2011 Jun 24.

PMID:
21726561
14.

Glycosphingolipid functions.

Lingwood CA.

Cold Spring Harb Perspect Biol. 2011 Jul 1;3(7). pii: a004788. doi: 10.1101/cshperspect.a004788. Review. Erratum in: Cold Spring Harb Perspect Biol. 2011 Sep;3(9):a011874.

15.

The role of glycosphingolipids in HIV/AIDS.

Lingwood CA, Branch DR.

Discov Med. 2011 Apr;11(59):303-13. Review.

16.

Adamantyl glycosphingolipids provide a new approach to the selective regulation of cellular glycosphingolipid metabolism.

Kamani M, Mylvaganam M, Tian R, Rigat B, Binnington B, Lingwood C.

J Biol Chem. 2011 Jun 17;286(24):21413-26. doi: 10.1074/jbc.M110.207670. Epub 2011 Apr 25.

17.

Cholesterol modulates glycolipid conformation and receptor activity.

Lingwood D, Binnington B, Róg T, Vattulainen I, Grzybek M, Coskun U, Lingwood CA, Simons K.

Nat Chem Biol. 2011 May;7(5):260-2. doi: 10.1038/nchembio.551. Epub 2011 Apr 3.

PMID:
21460830
18.

Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells.

Emam A, Carter WG, Lingwood C.

Open Microbiol J. 2010 Dec 13;4:106-15. doi: 10.2174/1874285801004010106.

19.

A major fraction of glycosphingolipids in model and cellular cholesterol-containing membranes is undetectable by their binding proteins.

Mahfoud R, Manis A, Binnington B, Ackerley C, Lingwood CA.

J Biol Chem. 2010 Nov 12;285(46):36049-59. doi: 10.1074/jbc.M110.110189. Epub 2010 Aug 17.

20.

A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms.

Harrison AL, Olsson ML, Jones RB, Ramkumar S, Sakac D, Binnington B, Henry S, Lingwood CA, Branch DR.

Glycoconj J. 2010 Jul;27(5):515-24. doi: 10.1007/s10719-010-9297-y. Epub 2010 Jun 26.

PMID:
20582467
21.

Globotriaosyl ceramide receptor function - where membrane structure and pathology intersect.

Lingwood CA, Binnington B, Manis A, Branch DR.

FEBS Lett. 2010 May 3;584(9):1879-86. doi: 10.1016/j.febslet.2009.11.089. Epub 2009 Dec 2. Review.

22.

New aspects of the regulation of glycosphingolipid receptor function.

Lingwood CA, Manis A, Mahfoud R, Khan F, Binnington B, Mylvaganam M.

Chem Phys Lipids. 2010 Jan;163(1):27-35. doi: 10.1016/j.chemphyslip.2009.09.001. Review.

PMID:
19781539
23.

A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation.

Park HJ, Mylvaganum M, McPherson A, Fewell SW, Brodsky JL, Lingwood CA.

Chem Biol. 2009 Apr 24;16(4):461-70. doi: 10.1016/j.chembiol.2009.02.014.

24.

Detergent-resistant globotriaosyl ceramide may define verotoxin/glomeruli-restricted hemolytic uremic syndrome pathology.

Khan F, Proulx F, Lingwood CA.

Kidney Int. 2009 Jun;75(11):1209-1216. doi: 10.1038/ki.2009.7. Epub 2009 Feb 11.

25.

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.

Wright CM, Seguin SP, Fewell SW, Zhang H, Ishwad C, Vats A, Lingwood CA, Wipf P, Fanning E, Pipas JM, Brodsky JL.

Virus Res. 2009 Apr;141(1):71-80. doi: 10.1016/j.virusres.2008.12.018. Epub 2009 Feb 4.

26.

Oxidation of the primary hydroxyl group of galactose of galactaosyl ceramide analogue by chemical method-precursors for the synthesis of labeled conjugates.

Yonekawa S, Lingwood CA, Mylvaganam M.

Carbohydr Res. 2009 Mar 10;344(4):501-6. doi: 10.1016/j.carres.2008.12.002. Epub 2008 Dec 11.

PMID:
19144327
27.

The human P(k) histo-blood group antigen provides protection against HIV-1 infection.

Lund N, Olsson ML, Ramkumar S, Sakac D, Yahalom V, Levene C, Hellberg A, Ma XZ, Binnington B, Jung D, Lingwood CA, Branch DR.

Blood. 2009 May 14;113(20):4980-91. doi: 10.1182/blood-2008-03-143396. Epub 2009 Jan 12.

PMID:
19139081
28.

Induction of HIV-1 resistance: cell susceptibility to infection is an inverse function of globotriaosyl ceramide levels.

Ramkumar S, Sakac D, Binnington B, Branch DR, Lingwood CA.

Glycobiology. 2009 Jan;19(1):76-82. doi: 10.1093/glycob/cwn106. Epub 2008 Oct 8.

PMID:
18842961
29.

Fatty acid-dependent globotriaosyl ceramide receptor function in detergent resistant model membranes.

Mahfoud R, Manis A, Lingwood CA.

J Lipid Res. 2009 Sep;50(9):1744-55. doi: 10.1194/jlr.M800385-JLR200. Epub 2008 Aug 20.

30.

Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein.

Fujii J, Wood K, Matsuda F, Carneiro-Filho BA, Schlegel KH, Yutsudo T, Binnington-Boyd B, Lingwood CA, Obata F, Kim KS, Yoshida S, Obrig T.

Infect Immun. 2008 Aug;76(8):3679-89. doi: 10.1128/IAI.01581-07. Epub 2008 Jun 9.

31.

Differential intracellular transport and binding of verotoxin 1 and verotoxin 2 to globotriaosylceramide-containing lipid assemblies.

Tam P, Mahfoud R, Nutikka A, Khine AA, Binnington B, Paroutis P, Lingwood C.

J Cell Physiol. 2008 Sep;216(3):750-63. doi: 10.1002/jcp.21456.

PMID:
18446787
32.

The medium is the message: glycosphingolipids and their soluble analogues.

De Rosa M, Park HJ, Mylvaganum M, Binnington B, Lund N, Branch DR, Lingwood CA.

Biochim Biophys Acta. 2008 Mar;1780(3):347-52. Epub 2007 Nov 4. Review.

PMID:
18022400
33.

Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.

De Rosa MF, Ackerley C, Wang B, Ito S, Clarke DM, Lingwood C.

J Biol Chem. 2008 Feb 22;283(8):4501-11. Epub 2007 Nov 13.

34.

Membrane cytosolic translocation of verotoxin A1 subunit in target cells.

Tam PJ, Lingwood CA.

Microbiology. 2007 Aug;153(Pt 8):2700-2710. doi: 10.1099/mic.0.2007/006858-0.

PMID:
17660434
35.

Soluble adamantyl glycosphingolipid analogs as probes of glycosphingolipid function.

Lingwood C, Sadacharan S, Abul-Milh M, Mylvaganum M, Peter M.

Methods Mol Biol. 2006;347:305-20. Review.

PMID:
17072019
36.

Laboratory and clinical Pseudomonas aeruginosa strains do not bind glycosphingolipids in vitro or during type IV pili-mediated initial host cell attachment.

Emam A, Yu AR, Park HJ, Mahfoud R, Kus J, Burrows LL, Lingwood CA.

Microbiology. 2006 Sep;152(Pt 9):2789-2799. doi: 10.1099/mic.0.28863-0.

PMID:
16946273
37.
38.

A novel soluble mimic of the glycolipid, globotriaosyl ceramide inhibits HIV infection.

Lund N, Branch DR, Mylvaganam M, Chark D, Ma XZ, Sakac D, Binnington B, Fantini J, Puri A, Blumenthal R, Lingwood CA.

AIDS. 2006 Feb 14;20(3):333-43.

PMID:
16439866
39.

Lack of susceptibility of cells from patients with Fabry disease to productive infection with R5 human immunodeficiency virus.

Lund N, Branch DR, Sakac D, Lingwood CA, Siatskas C, Robinson CJ, Brady RO, Medin JA.

AIDS. 2005 Sep 23;19(14):1543-6.

PMID:
16135910
40.
41.

Brefeldin A and filipin distinguish two globotriaosyl ceramide/verotoxin-1 intracellular trafficking pathways involved in Vero cell cytotoxicity.

Khine AA, Tam P, Nutikka A, Lingwood CA.

Glycobiology. 2004 Aug;14(8):701-12. Epub 2004 Apr 21.

PMID:
15102715
42.

Synergistic effect of verotoxin and interferon-alpha on erythropoiesis.

Maloney M, Lingwood C.

Cell Mol Biol (Noisy-le-grand). 2003 Dec;49(8):1363-9.

PMID:
14984011
44.
45.

Differential carbohydrate epitope recognition of globotriaosyl ceramide by verotoxins and a monoclonal antibody.

Chark D, Nutikka A, Trusevych N, Kuzmina J, Lingwood C.

Eur J Biochem. 2004 Jan;271(2):405-17.

46.

Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis.

De Rosa MF, Sillence D, Ackerley C, Lingwood C.

J Biol Chem. 2004 Feb 27;279(9):7867-76. Epub 2003 Dec 8.

47.

Lipid modulation of glycosphingolipid (GSL) receptors: soluble GSL mimics provide new probes of GSL receptor function.

Lingwood CA, Mylvaganam M.

Methods Enzymol. 2003;363:264-83. No abstract available.

PMID:
14579581
48.

Verotoxin 1 binding to intestinal crypt epithelial cells results in localization to lysosomes and abrogation of toxicity.

Hoey DE, Sharp L, Currie C, Lingwood CA, Gally DL, Smith DG.

Cell Microbiol. 2003 Feb;5(2):85-97.

PMID:
12580945
49.

3'Sulfogalactolipid binding specifically inhibits Hsp70 ATPase activity in vitro.

Whetstone H, Lingwood C.

Biochemistry. 2003 Feb 18;42(6):1611-7.

PMID:
12578374
50.

Induction by sphingomyelinase of shiga toxin receptor and shiga toxin 2 sensitivity in human microvascular endothelial cells.

Obrig TG, Seaner RM, Bentz M, Lingwood CA, Boyd B, Smith A, Narrow W.

Infect Immun. 2003 Feb;71(2):845-9.

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