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Items: 1 to 50 of 99

1.

CSL controls telomere maintenance and genome stability in human dermal fibroblasts.

Bottoni G, Katarkar A, Tassone B, Ghosh S, Clocchiatti A, Goruppi S, Bordignon P, Jafari P, Tordini F, Lunardi T, Hoetzenecker W, Neel V, Lingner J, Paolo Dotto G.

Nat Commun. 2019 Aug 29;10(1):3884. doi: 10.1038/s41467-019-11785-7.

2.

Expression and differential regulation of human TERRA at several chromosome ends.

Feretzaki M, Renck Nunes P, Lingner J.

RNA. 2019 Nov;25(11):1470-1480. doi: 10.1261/rna.072322.119. Epub 2019 Jul 26.

PMID:
31350341
3.

Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1.

Majerska J, Feretzaki M, Glousker G, Lingner J.

Life Sci Alliance. 2018 Jul 17;1(4):e201800121. doi: 10.26508/lsa.201800121. eCollection 2018 Aug.

4.

PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase.

Ahmed W, Lingner J.

Genes Dev. 2018 May 1;32(9-10):658-669. doi: 10.1101/gad.313460.118. Epub 2018 May 17.

5.

When Telomerase Causes Telomere Loss.

Glousker G, Lingner J.

Dev Cell. 2018 Feb 5;44(3):281-283. doi: 10.1016/j.devcel.2018.01.011. Epub 2018 Feb 5.

6.

Impact of oxidative stress on telomere biology.

Ahmed W, Lingner J.

Differentiation. 2018 Jan - Feb;99:21-27. doi: 10.1016/j.diff.2017.12.002. Epub 2017 Dec 14. Review.

PMID:
29274896
7.

The telomeric DNA damage response occurs in the absence of chromatin decompaction.

Vancevska A, Douglass KM, Pfeiffer V, Manley S, Lingner J.

Genes Dev. 2017 Mar 15;31(6):567-577. doi: 10.1101/gad.294082.116. Epub 2017 Apr 5.

8.

TZAP or not to zap telomeres.

Lossaint G, Lingner J.

Science. 2017 Feb 10;355(6325):578-579. doi: 10.1126/science.aam7015. No abstract available.

PMID:
28183935
9.

Peroxiredoxin 1 Protects Telomeres from Oxidative Damage and Preserves Telomeric DNA for Extension by Telomerase.

Aeby E, Ahmed W, Redon S, Simanis V, Lingner J.

Cell Rep. 2016 Dec 20;17(12):3107-3114. doi: 10.1016/j.celrep.2016.11.071.

10.

A practical qPCR approach to detect TERRA, the elusive telomeric repeat-containing RNA.

Feretzaki M, Lingner J.

Methods. 2017 Feb 1;114:39-45. doi: 10.1016/j.ymeth.2016.08.004. Epub 2016 Aug 12. Review.

11.

Quantitative telomeric chromatin isolation protocol for human cells.

Majerská J, Redon S, Lingner J.

Methods. 2017 Feb 1;114:28-38. doi: 10.1016/j.ymeth.2016.08.003. Epub 2016 Aug 9.

12.

ALT telomeres get together with nuclear receptors.

Aeby E, Lingner J.

Cell. 2015 Feb 26;160(5):811-813. doi: 10.1016/j.cell.2015.02.006.

13.

Functional characterization of the TERRA transcriptome at damaged telomeres.

Porro A, Feuerhahn S, Delafontaine J, Riethman H, Rougemont J, Lingner J.

Nat Commun. 2014 Oct 31;5:5379. doi: 10.1038/ncomms6379.

14.

Telomere functions grounding on TERRA firma.

Azzalin CM, Lingner J.

Trends Cell Biol. 2015 Jan;25(1):29-36. doi: 10.1016/j.tcb.2014.08.007. Epub 2014 Sep 23. Review.

PMID:
25257515
15.

The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7.

Zemp I, Lingner J.

J Biol Chem. 2014 Oct 10;289(41):28595-606. doi: 10.1074/jbc.M114.596056. Epub 2014 Aug 29.

16.

TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres.

Porro A, Feuerhahn S, Lingner J.

Cell Rep. 2014 Feb 27;6(4):765-76. doi: 10.1016/j.celrep.2014.01.022. Epub 2014 Feb 13.

17.

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.

Grolimund L, Aeby E, Hamelin R, Armand F, Chiappe D, Moniatte M, Lingner J.

Nat Commun. 2013;4:2848. doi: 10.1038/ncomms3848.

PMID:
24270157
18.

Molecular basis of telomere syndrome caused by CTC1 mutations.

Chen LY, Majerská J, Lingner J.

Genes Dev. 2013 Oct 1;27(19):2099-108. doi: 10.1101/gad.222893.113.

19.

The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening.

Pfeiffer V, Crittin J, Grolimund L, Lingner J.

EMBO J. 2013 Oct 30;32(21):2861-71. doi: 10.1038/emboj.2013.217. Epub 2013 Oct 1.

20.

A three-state model for the regulation of telomerase by TERRA and hnRNPA1.

Redon S, Zemp I, Lingner J.

Nucleic Acids Res. 2013 Oct;41(19):9117-28. doi: 10.1093/nar/gkt695. Epub 2013 Aug 8.

21.

CST for the grand finale of telomere replication.

Chen LY, Lingner J.

Nucleus. 2013 Jul-Aug;4(4):277-82. doi: 10.4161/nucl.25701. Epub 2013 Jul 10.

22.

Replication of telomeres and the regulation of telomerase.

Pfeiffer V, Lingner J.

Cold Spring Harb Perspect Biol. 2013 May 1;5(5):a010405. doi: 10.1101/cshperspect.a010405. Review.

23.

Structure of active dimeric human telomerase.

Sauerwald A, Sandin S, Cristofari G, Scheres SH, Lingner J, Rhodes D.

Nat Struct Mol Biol. 2013 Apr;20(4):454-60. doi: 10.1038/nsmb.2530. Epub 2013 Mar 10.

24.

Telomerase inhibitors from cyanobacteria: isolation and synthesis of sulfoquinovosyl diacylglycerols from Microcystis aeruguinosa PCC 7806.

Makhlouf Brahmi M, Portmann C, D'Ambrosio D, Woods TM, Banfi D, Reichenbach P, Da Silva L, Baudat E, Turcatti G, Lingner J, Gademann K.

Chemistry. 2013 Apr 2;19(14):4596-601. doi: 10.1002/chem.201203296. Epub 2013 Jan 31.

PMID:
23364876
25.

Telomere length homeostasis responds to changes in intracellular dNTP pools.

Gupta A, Sharma S, Reichenbach P, Marjavaara L, Nilsson AK, Lingner J, Chabes A, Rothstein R, Chang M.

Genetics. 2013 Apr;193(4):1095-105. doi: 10.1534/genetics.112.149120. Epub 2013 Jan 18.

26.

AUF1/HnRNP D RNA binding protein functions in telomere maintenance.

Chen LY, Lingner J.

Mol Cell. 2012 Jul 13;47(1):1-2. doi: 10.1016/j.molcel.2012.06.031.

27.

The human CST complex is a terminator of telomerase activity.

Chen LY, Redon S, Lingner J.

Nature. 2012 Aug 23;488(7412):540-4. doi: 10.1038/nature11269.

PMID:
22763445
28.

TERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome ends.

Pfeiffer V, Lingner J.

PLoS Genet. 2012;8(6):e1002747. doi: 10.1371/journal.pgen.1002747. Epub 2012 Jun 14.

29.

Specific binding of telomeric G-quadruplexes by hydrosoluble perylene derivatives inhibits repeat addition processivity of human telomerase.

D'Ambrosio D, Reichenbach P, Micheli E, Alvino A, Franceschin M, Savino M, Lingner J.

Biochimie. 2012 Mar;94(3):854-63. doi: 10.1016/j.biochi.2011.12.004. Epub 2011 Dec 9.

PMID:
22182489
30.

The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.

Ferreira HC, Luke B, Schober H, Kalck V, Lingner J, Gasser SM.

Nat Cell Biol. 2011 Jun 12;13(7):867-74. doi: 10.1038/ncb2263.

PMID:
21666682
31.

Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast.

Iglesias N, Redon S, Pfeiffer V, Dees M, Lingner J, Luke B.

EMBO Rep. 2011 Jun;12(6):587-93. doi: 10.1038/embor.2011.73. Epub 2011 Apr 28.

32.

Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways.

Porro A, Feuerhahn S, Reichenbach P, Lingner J.

Mol Cell Biol. 2010 Oct;30(20):4808-17. doi: 10.1128/MCB.00460-10. Epub 2010 Aug 16.

33.

TERRA biogenesis, turnover and implications for function.

Feuerhahn S, Iglesias N, Panza A, Porro A, Lingner J.

FEBS Lett. 2010 Sep 10;584(17):3812-8. doi: 10.1016/j.febslet.2010.07.032. Epub 2010 Jul 23. Review.

34.

The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase.

Redon S, Reichenbach P, Lingner J.

Nucleic Acids Res. 2010 Sep;38(17):5797-806. doi: 10.1093/nar/gkq296. Epub 2010 May 11.

35.

TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo.

Abreu E, Aritonovska E, Reichenbach P, Cristofari G, Culp B, Terns RM, Lingner J, Terns MP.

Mol Cell Biol. 2010 Jun;30(12):2971-82. doi: 10.1128/MCB.00240-10. Epub 2010 Apr 19.

36.

Telomerase is essential to alleviate pif1-induced replication stress at telomeres.

Chang M, Luke B, Kraft C, Li Z, Peter M, Lingner J, Rothstein R.

Genetics. 2009 Nov;183(3):779-91. doi: 10.1534/genetics.109.107631. Epub 2009 Aug 24.

37.

Related mechanisms for end processing at telomeres and DNA double-strand breaks.

Iglesias N, Lingner J.

Mol Cell. 2009 Jul 31;35(2):137-8. doi: 10.1016/j.molcel.2009.07.007.

38.

TERRA: telomeric repeat-containing RNA.

Luke B, Lingner J.

EMBO J. 2009 Sep 2;28(17):2503-10. doi: 10.1038/emboj.2009.166. Epub 2009 Jul 23. Review.

39.

The Rat1p 5' to 3' exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae.

Luke B, Panza A, Redon S, Iglesias N, Li Z, Lingner J.

Mol Cell. 2008 Nov 21;32(4):465-77. doi: 10.1016/j.molcel.2008.10.019.

40.

An affinity oligonucleotide displacement strategy to purify ribonucleoprotein complexes applied to human telomerase.

Kurth I, Cristofari G, Lingner J.

Methods Mol Biol. 2008;488:9-22. doi: 10.1007/978-1-60327-475-3_2.

PMID:
18982281
41.

Telomeres: the silence is broken.

Azzalin CM, Lingner J.

Cell Cycle. 2008 May 1;7(9):1161-5. Epub 2008 Mar 4. Review.

PMID:
18418035
42.

Cell signaling. Tel2 finally tells one story.

Chang M, Lingner J.

Science. 2008 Apr 4;320(5872):60-1. doi: 10.1126/science.1155132. No abstract available.

PMID:
18388281
43.

Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.

Luke B, Azzalin CM, Hug N, Deplazes A, Peter M, Lingner J.

Nucleic Acids Res. 2007;35(22):7688-97. Epub 2007 Nov 4.

44.

Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action.

De Cian A, Cristofari G, Reichenbach P, De Lemos E, Monchaud D, Teulade-Fichou MP, Shin-Ya K, Lacroix L, Lingner J, Mergny JL.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17347-52. Epub 2007 Oct 22.

45.

Protein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomerase.

Redon S, Reichenbach P, Lingner J.

Nucleic Acids Res. 2007;35(20):7011-22. Epub 2007 Oct 16.

46.
47.

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.

Azzalin CM, Reichenbach P, Khoriauli L, Giulotto E, Lingner J.

Science. 2007 Nov 2;318(5851):798-801. Epub 2007 Oct 4.

49.

Low- to high-throughput analysis of telomerase modulators with Telospot.

Cristofari G, Reichenbach P, Regamey PO, Banfi D, Chambon M, Turcatti G, Lingner J.

Nat Methods. 2007 Oct;4(10):851-3.

PMID:
17893679
50.

Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation.

Cristofari G, Adolf E, Reichenbach P, Sikora K, Terns RM, Terns MP, Lingner J.

Mol Cell. 2007 Sep 21;27(6):882-9.

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