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In vivo biotransformations of indium phosphide quantum dots revealed by X-ray micro-spectroscopy.

Veronesi G, Moros M, Castillo-Michel HA, Mattera L, Onorato G, Wegner KDD, Ling WL, Reiss P, Tortiglione C.

ACS Appl Mater Interfaces. 2019 Sep 9. doi: 10.1021/acsami.9b15433. [Epub ahead of print]


Influence of the Core/Shell Structure of Indium Phosphide Based Quantum Dots on Their Photostability and Cytotoxicity.

Wegner KD, Dussert F, Truffier-Boutry D, Benayad A, Beal D, Mattera L, Ling WL, Carrière M, Reiss P.

Front Chem. 2019 Jun 27;7:466. doi: 10.3389/fchem.2019.00466. eCollection 2019.


Polymer-grafted chromatography media for the purification of enveloped virus-like particles, exemplified with HIV-1 gag VLP.

Pereira Aguilar P, Schneider TA, Wetter V, Maresch D, Ling WL, Tover A, Steppert P, Jungbauer A.

Vaccine. 2019 Jul 9. pii: S0264-410X(19)30878-3. doi: 10.1016/j.vaccine.2019.07.001. [Epub ahead of print]


Role of the IgE variable heavy chain in FcεRIα and superantigen binding in allergy and immunotherapy.

Lua WH, Su CT, Yeo JY, Poh JJ, Ling WL, Phua SX, Gan SK.

J Allergy Clin Immunol. 2019 Aug;144(2):514-523.e5. doi: 10.1016/j.jaci.2019.03.028. Epub 2019 Apr 14.


Gallium - a versatile element for tuning the photoluminescence properties of InP quantum dots.

Wegner KD, Pouget S, Ling WL, Carrière M, Reiss P.

Chem Commun (Camb). 2019 Jan 31;55(11):1663-1666. doi: 10.1039/c8cc09740b.


Measuring Particle Size Distribution by Asymmetric Flow Field Flow Fractionation: A Powerful Method for the Preclinical Characterization of Lipid-Based Nanoparticles.

Caputo F, Arnould A, Bacia M, Ling WL, Rustique E, Texier I, Mello AP, Couffin AC.

Mol Pharm. 2019 Feb 4;16(2):756-767. doi: 10.1021/acs.molpharmaceut.8b01033. Epub 2019 Jan 16.


Recognition protein C1q of innate immunity agglutinates nanodiamonds without activating complement.

Belime A, Thielens NM, Gravel E, Frachet P, Ancelet S, Tacnet P, Caneiro C, Chuprin J, Gaboriaud C, Schoehn G, Doris E, Ling WL.

Nanomedicine. 2019 Jun;18:292-302. doi: 10.1016/j.nano.2018.09.009. Epub 2018 Oct 24.


Effect of VH-VL Families in Pertuzumab and Trastuzumab Recombinant Production, Her2 and FcγIIA Binding.

Ling WL, Lua WH, Poh JJ, Yeo JY, Lane DP, Gan SK.

Front Immunol. 2018 Mar 12;9:469. doi: 10.3389/fimmu.2018.00469. eCollection 2018.


Dynamic self-assembly of DNA minor groove-binding ligand DB921 into nanotubes triggered by an alkali halide.

Mizuta R, Devos JM, Webster J, Ling WL, Narayanan T, Round A, Munnur D, Mossou E, Farahat AA, Boykin DW, Wilson WD, Neidle S, Schweins R, Rannou P, Haertlein M, Forsyth VT, Mitchell EP.

Nanoscale. 2018 Mar 28;10(12):5550-5558. doi: 10.1039/c7nr03875e. Epub 2018 Mar 8.


The effects of Antibody Engineering CH and CL in Trastuzumab and Pertuzumab recombinant models: Impact on antibody production and antigen-binding.

Lua WH, Ling WL, Yeo JY, Poh JJ, Lane DP, Gan SK.

Sci Rep. 2018 Jan 15;8(1):718. doi: 10.1038/s41598-017-18892-9. Erratum in: Sci Rep. 2018 Jul 18;8(1):11110.


Impact of the surface charge of polydiacetylene micelles on their interaction with human innate immune protein C1q and the complement system.

Thielens NM, Belime A, Gravel E, Ancelet S, Caneiro C, Doris E, Ling WL.

Int J Pharm. 2018 Jan 30;536(1):434-439. doi: 10.1016/j.ijpharm.2017.11.072. Epub 2017 Dec 5.


Analysis of XFEL serial diffraction data from individual crystalline fibrils.

Wojtas DH, Ayyer K, Liang M, Mossou E, Romoli F, Seuring C, Beyerlein KR, Bean RJ, Morgan AJ, Oberthuer D, Fleckenstein H, Heymann M, Gati C, Yefanov O, Barthelmess M, Ornithopoulou E, Galli L, Xavier PL, Ling WL, Frank M, Yoon CH, White TA, Bajt S, Mitraki A, Boutet S, Aquila A, Barty A, Forsyth VT, Chapman HN, Millane RP.

IUCrJ. 2017 Oct 20;4(Pt 6):795-811. doi: 10.1107/S2052252517014324. eCollection 2017 Nov 1.


Mode of PEG Coverage on Carbon Nanotubes Affects Binding of Innate Immune Protein C1q.

Belime A, Gravel E, Brenet S, Ancelet S, Caneiro C, Hou Y, Thielens N, Doris E, Ling WL.

J Phys Chem B. 2018 Jan 18;122(2):757-763. doi: 10.1021/acs.jpcb.7b06596. Epub 2017 Sep 27.


Structure of the C1 complex of complement.

Arlaud GJ, Gaboriaud C, Ling WL, Thielens NM.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5766-E5767. doi: 10.1073/pnas.1703977114. Epub 2017 Jul 12. No abstract available.


The role of Antibody Vκ Framework 3 region towards Antigen binding: Effects on recombinant production and Protein L binding.

Su CT, Ling WL, Lua WH, Poh JJ, Gan SK.

Sci Rep. 2017 Jun 19;7(1):3766. doi: 10.1038/s41598-017-02756-3.


Human Immune Protein C1q Selectively Disaggregates Carbon Nanotubes.

Saint-Cricq M, Carrete J, Gaboriaud C, Gravel E, Doris E, Thielens N, Mingo N, Ling WL.

Nano Lett. 2017 Jun 14;17(6):3409-3415. doi: 10.1021/acs.nanolett.7b00189. Epub 2017 May 30.


Structural analyses of 2015-updated drug-resistant mutations in HIV-1 protease: an implication of protease inhibitor cross-resistance.

Su CT, Ling WL, Lua WH, Haw YX, Gan SK.

BMC Bioinformatics. 2016 Dec 22;17(Suppl 19):500. doi: 10.1186/s12859-016-1372-3.


Discovery of a novel splice variant of Fcar (CD89) unravels sequence segments necessary for efficient secretion: A story of bad signal peptides and good ones that nevertheless do not make it.

Lua WH, Ling WL, Su CT, Yeo JY, Verma CS, Eisenhaber B, Eisenhaber F, Gan SK.

Cell Cycle. 2017 Mar 4;16(5):457-467. doi: 10.1080/15384101.2017.1281480. Epub 2017 Jan 19.


Ultrafast and high-throughput N-glycan analysis for monoclonal antibodies.

Yang X, Kim SM, Ruzanski R, Chen Y, Moses S, Ling WL, Li X, Wang SC, Li H, Ambrogelly A, Richardson D, Shameem M.

MAbs. 2016 May-Jun;8(4):706-17. doi: 10.1080/19420862.2016.1156828. Epub 2016 Apr 15.


Domain Organization of Vaccinia Virus Helicase-Primase D5.

Hutin S, Ling WL, Round A, Effantin G, Reich S, Iseni F, Tarbouriech N, Schoehn G, Burmeister WP.

J Virol. 2016 Apr 14;90(9):4604-4613. doi: 10.1128/JVI.00044-16. Print 2016 May.


MiR-1303 Regulates Mycobacteria Induced Autophagy by Targeting Atg2B.

Au KY, Pong JC, Ling WL, Li JC.

PLoS One. 2016 Jan 15;11(1):e0146770. doi: 10.1371/journal.pone.0146770. eCollection 2016.


Development and manufacturability assessment of chemically-defined medium for the production of protein therapeutics in CHO cells.

Ling WL, Bai Y, Cheng C, Padawer I, Wu C.

Biotechnol Prog. 2015 Sep-Oct;31(5):1163-71. doi: 10.1002/btpr.2108. Epub 2015 Jun 22.


Structural virology. Near-atomic cryo-EM structure of the helical measles virus nucleocapsid.

Gutsche I, Desfosses A, Effantin G, Ling WL, Haupt M, Ruigrok RW, Sachse C, Schoehn G.

Science. 2015 May 8;348(6235):704-7. doi: 10.1126/science.aaa5137. Epub 2015 Apr 16.


Fast reversible single-step method for enhanced band contrast of polyacrylamide gels for automated detection.

Ling WL, Lua WH, Gan SK.

Electrophoresis. 2015 May;36(9-10):1224-7. doi: 10.1002/elps.201500094. Epub 2015 May 5.


Deciphering the fine details of c1 assembly and activation mechanisms: "mission impossible"?

Gaboriaud C, Ling WL, Thielens NM, Bally I, Rossi V.

Front Immunol. 2014 Nov 6;5:565. doi: 10.3389/fimmu.2014.00565. eCollection 2014. Review.


A role for interleukin-17A in modulating intracellular survival of Mycobacterium bovis bacillus Calmette-Guérin in murine macrophages.

Ling WL, Wang LJ, Pong JC, Lau AS, Li JC.

Immunology. 2013 Nov;140(3):323-34. doi: 10.1111/imm.12140.


Case Study: an accelerated 8-day monoclonal antibody production process based on high seeding densities.

Padawer I, Ling WL, Bai Y.

Biotechnol Prog. 2013 May-Jun;29(3):829-32. doi: 10.1002/btpr.1719. Epub 2013 Apr 18.


Enzymatically modified low-density lipoprotein is recognized by c1q and activates the classical complement pathway.

Arlaud GJ, Biro A, Ling WL.

J Lipids. 2011;2011:376092. doi: 10.1155/2011/376092. Epub 2011 Mar 9.


X-ray structure of the human calreticulin globular domain reveals a peptide-binding area and suggests a multi-molecular mechanism.

Chouquet A, Païdassi H, Ling WL, Frachet P, Houen G, Arlaud GJ, Gaboriaud C.

PLoS One. 2011 Mar 15;6(3):e17886. doi: 10.1371/journal.pone.0017886.


Investigations on the C1q-calreticulin-phosphatidylserine interactions yield new insights into apoptotic cell recognition.

Païdassi H, Tacnet-Delorme P, Verneret M, Gaboriaud C, Houen G, Duus K, Ling WL, Arlaud GJ, Frachet P.

J Mol Biol. 2011 Apr 29;408(2):277-90. doi: 10.1016/j.jmb.2011.02.029. Epub 2011 Feb 23.


Role of iron and sodium citrate in animal protein-free CHO cell culture medium on cell growth and monoclonal antibody production.

Bai Y, Wu C, Zhao J, Liu YH, Ding W, Ling WL.

Biotechnol Prog. 2011 Jan-Feb;27(1):209-19. doi: 10.1002/btpr.513. Epub 2010 Nov 23.


Proteins of the innate immune system crystallize on carbon nanotubes but are not activated.

Ling WL, Biro A, Bally I, Tacnet P, Deniaud A, Doris E, Frachet P, Schoehn G, Pebay-Peyroula E, Arlaud GJ.

ACS Nano. 2011 Feb 22;5(2):730-7. doi: 10.1021/nn102400w. Epub 2011 Jan 7.


Identification of liver proteins and their roles associated with carbon tetrachloride-induced hepatotoxicity.

Wong LL, Fan ST, Man K, Sit WH, Jiang PP, Jor IW, Lee CY, Ling WL, Tam KT, Wan JM.

Hum Exp Toxicol. 2011 Sep;30(9):1369-81. doi: 10.1177/0960327110391388. Epub 2010 Dec 7.


Lanthanide-chelate silica nanospheres as robust multicolor Vis-NIR tags.

Samuel J, Tallec G, Cherns P, Ling WL, Raccurt O, Poncelet O, Imbert D, Mazzanti M.

Chem Commun (Camb). 2010 Apr 21;46(15):2647-9. doi: 10.1039/b926031e. Epub 2010 Feb 4.


Complement protein C1q forms a complex with cytotoxic prion protein oligomers.

Erlich P, Dumestre-Pérard C, Ling WL, Lemaire-Vieille C, Schoehn G, Arlaud GJ, Thielens NM, Gagnon J, Cesbron JY.

J Biol Chem. 2010 Jun 18;285(25):19267-76. doi: 10.1074/jbc.M109.071860. Epub 2010 Apr 21.


Twin boundaries can be moved by step edges during film growth.

Ling WL, Bartelt NC, McCarty KF, Carter CB.

Phys Rev Lett. 2005 Oct 14;95(16):166105. Epub 2005 Oct 13.


Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti-IGF-IR antibody.

Wang Y, Hailey J, Williams D, Wang Y, Lipari P, Malkowski M, Wang X, Xie L, Li G, Saha D, Ling WL, Cannon-Carlson S, Greenberg R, Ramos RA, Shields R, Presta L, Brams P, Bishop WR, Pachter JA.

Mol Cancer Ther. 2005 Aug;4(8):1214-21.


The importance of threading dislocations on the motion of domain boundaries in thin films.

El Gabaly F, Ling WL, McCarty KF, de la Figuera J.

Science. 2005 May 27;308(5726):1303-5.


Recycling lower continental crust in the North China craton.

Gao S, Rudnick RL, Yuan HL, Liu XM, Liu YS, Xu WL, Ling WL, Ayers J, Wang XC, Wang QH.

Nature. 2004 Dec 16;432(7019):892-7.


Enhanced self-diffusion on Cu(111) by trace amounts of s: chemical-reaction-limited kinetics.

Ling WL, Bartelt NC, Pohl K, de la Figuera J, Hwang RQ, McCarty KF.

Phys Rev Lett. 2004 Oct 15;93(16):166101. Epub 2004 Oct 13.


Strain relief through heterophase interface reconstruction: Ag(111)/Ru(0001).

Ling WL, de la Figuera J, Bartelt NC, Hwang RQ, Schmid AK, Thayer GE, Hamilton JC.

Phys Rev Lett. 2004 Mar 19;92(11):116102. Epub 2004 Mar 18.


Detection and quantification of the human IgG4 half-molecule, HL, from unpurified cell-culture supernatants.

Deng L, Wylie D, Tsao YS, Larkin B, Voloch M, Ling WL.

Biotechnol Appl Biochem. 2004 Dec;40(Pt 3):261-9.


Improvement of monoclonal antibody production in hybridoma cells by dimethyl sulfoxide.

Ling WL, Deng L, Lepore J, Cutler C, Cannon-Carlson S, Wang Y, Voloch M.

Biotechnol Prog. 2003 Jan-Feb;19(1):158-62.


Role of integrin alphaVbeta3 in the production of recombinant adenoviruses in HEK-293 cells.

Ling WL, Longley RL, Brassard DL, Armstrong L, Schaefer EJ.

Gene Ther. 2002 Jul;9(14):907-14.


Influence of hepatic arterial blockage on blood perfusion and VEGF, MMP-1 expression of implanted liver cancer in rats.

Guo WJ, Li J, Ling WL, Bai YR, Zhang WZ, Cheng YF, Gu WH, Zhuang JY.

World J Gastroenterol. 2002 Jun;8(3):476-9.


Protease inhibitors do not interfere with prohormone processing.

Danoff A, Ling WL.

Ann Intern Med. 2000 Feb 15;132(4):330. No abstract available.


The use of permeabilized cells to investigate secretory granule biogenesis.

Ling WL, Siddhanta A, Shields D.

Methods. 1998 Oct;16(2):141-9.


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