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Toll-like receptor-ligand induced thymic stromal lymphopoietin expression in primary equine keratinocytes.

Cvitas I, Galichet A, Ling SC, Müller EJ, Marti E.

Vet Dermatol. 2019 Nov 21. doi: 10.1111/vde.12813. [Epub ahead of print]


FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits.

Ho WY, Chang JC, Tyan SH, Yen YC, Lim K, Tan BSY, Ong J, Tucker-Kellogg G, Wong P, Koo E, Ling SC.

Hum Mol Genet. 2019 Nov 15;28(22):3777-3791. doi: 10.1093/hmg/ddz217.


Treatment of infants with hepatitis B virus: A window of opportunity?

Ling SC, Mogul D.

J Hepatol. 2019 Nov;71(5):856-858. doi: 10.1016/j.jhep.2019.08.007. Epub 2019 Sep 7. No abstract available.


Phenotypes of Chronic Hepatitis B in Children From a Large North American Cohort.

Schwarz KB, Lombardero M, Di Bisceglie AM, Murray KF, Rosenthal P, Ling SC, Cloonan YK, Rodriguez-Baez N, Schwarzenberg SJ, Hoofnagle JH, Teckman J; Hepatitis B Research Network (HBRN).

J Pediatr Gastroenterol Nutr. 2019 Nov;69(5):588-594. doi: 10.1097/MPG.0000000000002467.


Liver Ultrasound Patterns in Children With Cystic Fibrosis Correlate With Noninvasive Tests of Liver Disease.

Ling SC, Ye W, Leung DH, Navarro OM, Weymann A, Karnsakul W, Freeman AJ, Magee JC, Narkewicz MR.

J Pediatr Gastroenterol Nutr. 2019 Sep;69(3):351-357. doi: 10.1097/MPG.0000000000002413.


C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.

Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL 3rd, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC, Lee EB.

Acta Neuropathol. 2019 Nov;138(5):795-811. doi: 10.1007/s00401-019-02045-5. Epub 2019 Jul 20.


Magnetic Resonance Imaging Assessment of Blood Flow Distribution in Fenestrated and Completed Fontan Circulation with Special Emphasis on Abdominal Blood Flow.

Caro-Dominguez P, Chaturvedi R, Chavhan G, Ling SC, Yim D, Porayette P, Lam CZ, Kim TK, Seed M, Grosse-Wortmann L, Yoo SJ.

Korean J Radiol. 2019 Jul;20(7):1186-1194. doi: 10.3348/kjr.2018.0921.


Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Adolescents With Chronic Hepatitis C Virus: Part 1 of the DORA Study.

Jonas MM, Squires RH, Rhee SM, Lin CW, Bessho K, Feiterna-Sperling C, Hierro L, Kelly D, Ling SC, Strokova T, Del Valle-Segarra A, Lovell S, Liu W, Ng TI, Porcalla A, Gonzalez YS, Burroughs M, Sokal E.

Hepatology. 2019 Jun 29. doi: 10.1002/hep.30840. [Epub ahead of print]


Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis.

Ho WY, Ling SC.

Autophagy. 2019 Sep;15(9):1665-1667. doi: 10.1080/15548627.2019.1633162. Epub 2019 Jun 23.


Portal Angiogenesis in Chronic Liver Disease Patients Correlates with Portal Pressure and Collateral Formation.

Serrano CA, Ling SC, Verdaguer S, León M, Jarufe N, Guerra JF, Pattillo JC, Benítez C, Villagrán A, Torres J, Concha M, Villarroel L, Dellepiane P, Domínguez P, Martínez J, Gana JC.

Dig Dis. 2019;37(6):498-508. doi: 10.1159/000500115. Epub 2019 May 8.


Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B.

Di Bisceglie AM, King WC, Lisker-Melman M, Khalili M, Belle SH, Feld JJ, Ghany MG, Janssen HLA, Lau D, Lee WM, Ling SC, Cooper S, Rosenthal P, Schwarz KB, Sterling RK, Teckman JH, Terrault N; Hepatitis B Research Network (HBRN).

J Viral Hepat. 2019 Jul;26(7):856-865. doi: 10.1111/jvh.13104. Epub 2019 May 2.


Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.

Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW.

Elife. 2019 Feb 12;8. pii: e40811. doi: 10.7554/eLife.40811.


A Multidisciplinary Approach to Pretransplant and Posttransplant Management of Cystic Fibrosis-Associated Liver Disease.

Freeman AJ, Sellers ZM, Mazariegos G, Kelly A, Saiman L, Mallory G, Ling SC, Narkewicz MR, Leung DH.

Liver Transpl. 2019 Apr;25(4):640-657. doi: 10.1002/lt.25421. Epub 2019 Mar 20.


The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.

Ho WY, Tai YK, Chang JC, Liang J, Tyan SH, Chen S, Guan JL, Zhou H, Shen HM, Koo E, Ling SC.

Autophagy. 2019 May;15(5):827-842. doi: 10.1080/15548627.2019.1569441. Epub 2019 Jan 28.


Achieving High-quality Outcomes for Endoscopic Retrograde Cholangiopancreatography: Can Pediatricians Match the Adults, and Should They Try?

Ling SC, Walsh CM.

J Pediatr Gastroenterol Nutr. 2019 Jan;68(1):1-2. doi: 10.1097/MPG.0000000000002103. No abstract available.


Neurocognitive function, performance status, and quality of life in pediatric intracranial germ cell tumor survivors.

Tso WWY, Liu APY, Lee TMC, Cheuk KL, Shing MK, Luk CW, Ling SC, Ku DTL, Li K, Yung AWY, Fung CW, Chan SHS, Ho ACC, Ho FKW, Ip P, Chan GCF.

J Neurooncol. 2019 Jan;141(2):393-401. doi: 10.1007/s11060-018-03045-3. Epub 2018 Nov 20.


Can Pediatric Endoscopists Accurately Assess Their Clinical Competency? A Comparison Across Skill Levels.

Scaffidi MA, Khan R, Carnahan H, Ling SC, Lightdale JR, Mamula P, Yu JJ, Grover SC, Walsh CM.

J Pediatr Gastroenterol Nutr. 2019 Mar;68(3):311-317. doi: 10.1097/MPG.0000000000002191.


Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination.

Wang J, Ho WY, Lim K, Feng J, Tucker-Kellogg G, Nave KA, Ling SC.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10941-E10950. doi: 10.1073/pnas.1809821115. Epub 2018 Oct 29.


ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.

López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, Swing D, Qiu J, Hicks GG, Ouyang Z, Fu XD, Tessarollo L, Ling SC, Parone PA, Shaw CE, Marsala M, Lagier-Tourenne C, Cleveland DW, Da Cruz S.

Neuron. 2018 Nov 21;100(4):816-830.e7. doi: 10.1016/j.neuron.2018.09.044. Epub 2018 Oct 18.


Combination of Entecavir/Peginterferon Alfa-2a in Children With Hepatitis B e Antigen-Positive Immune Tolerant Chronic Hepatitis B Virus Infection.

Rosenthal P, Ling SC, Belle SH, Murray KF, Rodriguez-Baez N, Schwarzenberg SJ, Teckman J, Lin HS, Schwarz KB; Hepatitis B Research Network (HBRN).

Hepatology. 2019 Jun;69(6):2326-2337. doi: 10.1002/hep.30312. Epub 2019 Feb 20.


Analysis of a large cohort of cystic fibrosis patients with severe liver disease indicates lung function decline does not significantly differ from that of the general cystic fibrosis population.

Polineni D, Piccorelli AV, Hannah WB, Dalrymple SN, Pace RG, Durie PR, Ling SC, Knowles MR, Stonebraker JR.

PLoS One. 2018 Oct 11;13(10):e0205257. doi: 10.1371/journal.pone.0205257. eCollection 2018.


MiR-205 Mediated Cu-Induced Lipid Accumulation in Yellow Catfish Pelteobagrus fulvidraco.

Cui HY, Chen QL, Tan XY, Zhang DG, Ling SC, Chen GH, Luo Z.

Int J Mol Sci. 2018 Sep 29;19(10). pii: E2980. doi: 10.3390/ijms19102980.


SREBP1, PPARG and AMPK pathways mediated the Cu-induced change in intestinal lipogenesis and lipid transport of yellow catfish Pelteobagrus fulvidraco.

Chen GH, Luo Z, Hogstrand C, Wu K, Ling SC.

Food Chem. 2018 Dec 15;269:595-602. doi: 10.1016/j.foodchem.2018.07.048. Epub 2018 Jul 9.


Mitochondrial apoptotic pathway mediated the Zn-induced lipolysis in yellow catfish Peteobagrus fulvidraco.

Li DD, Luo Z, Ling SC, Wu K, Chen GH, Cheng J.

Chemosphere. 2018 Oct;208:907-915. doi: 10.1016/j.chemosphere.2018.05.200. Epub 2018 Jun 8.


Characteristics of Hepatitis B Virus-associated Hepatocellular Carcinoma in Children: A Multi-center Study.

Mogul DB, Ling SC, Murray KF, Schwarzenberg SJ, Rudzinski ER, Schwarz KB.

J Pediatr Gastroenterol Nutr. 2018 Oct;67(4):437-440. doi: 10.1097/MPG.0000000000002093.


Ooplasmic flow cooperates with transport and anchorage in Drosophila oocyte posterior determination.

Lu W, Lakonishok M, Serpinskaya AS, Kirchenbüechler D, Ling SC, Gelfand VI.

J Cell Biol. 2018 Oct 1;217(10):3497-3511. doi: 10.1083/jcb.201709174. Epub 2018 Jul 23.


Identification of full-length cDNA sequences for three development-relevant genes from yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to high fat diet.

Tai ZP, Li DD, Ling SC, Zhang DG, Cui HY, Tan XY.

Comp Biochem Physiol B Biochem Mol Biol. 2018 Nov;225:67-74. doi: 10.1016/j.cbpb.2018.07.004. Epub 2018 Jul 17.


Hepatic steatosis is highly prevalent across the paediatric age spectrum, including in pre-school age children.

Dhaliwal J, Chavhan GB, Lurz E, Shalabi A, Yuen N, Williams B, Martincevic I, Amirabadi A, Wales PW, Lee W, Ling SC, Mouzaki M.

Aliment Pharmacol Ther. 2018 Sep;48(5):556-563. doi: 10.1111/apt.14900. Epub 2018 Jul 11.


Acute Variceal Bleeding Causes Significant Morbidity.

Carneiro de Moura M, Chen S, Kamath BM, Ng VL, Ling SC.

J Pediatr Gastroenterol Nutr. 2018 Sep;67(3):371-376. doi: 10.1097/MPG.0000000000002039.


Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions.

Ling SC.

Neural Plast. 2018 Apr 11;2018:8413496. doi: 10.1155/2018/8413496. eCollection 2018. Review.


Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.

Bennett CL, Dastidar SG, Ling SC, Malik B, Ashe T, Wadhwa M, Miller DB, Lee C, Mitchell MB, van Es MA, Grunseich C, Chen Y, Sopher BL, Greensmith L, Cleveland DW, La Spada AR.

Acta Neuropathol. 2018 Sep;136(3):425-443. doi: 10.1007/s00401-018-1852-9. Epub 2018 May 3.


Outcomes and morbidities of patients who survive haemoglobin Bart's hydrops fetalis syndrome: 20-year retrospective review.

Chan WY, Leung AW, Luk CW, Li RC, Ling AS, Ha SY.

Hong Kong Med J. 2018 Apr;24(2):107-118. doi: 10.12809/hkmj176336. Epub 2018 Apr 6.


Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study.

Ng VL, Sorensen LG, Alonso EM, Fredericks EM, Ye W, Moore J, Karpen SJ, Shneider BL, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Rosenthal P, Squires RH, Wang K, Arnon R, Schwarz KB, Turmelle YP, Haber BH, Sherker AH, Magee JC, Sokol RJ; Childhood Liver Disease Research Network (ChiLDReN).

J Pediatr. 2018 May;196:139-147.e3. doi: 10.1016/j.jpeds.2017.12.048. Epub 2018 Mar 5.


New Onset Autoimmune Hepatitis during Anti-Tumor Necrosis Factor-Alpha Treatment in Children.

Ricciuto A, Kamath BM, Walters TD, Frost K, Carman N, Church PC, Ling SC, Griffiths AM.

J Pediatr. 2018 Mar;194:128-135.e1. doi: 10.1016/j.jpeds.2017.10.071. Epub 2017 Dec 21.


Waterborne Zn influenced Zn uptake and lipid metabolism in two intestinal regions of juvenile goby Synechogobius hasta.

Ling SC, Luo Z, Chen GH, Zhang DG, Liu X.

Ecotoxicol Environ Saf. 2018 Feb;148:578-584. doi: 10.1016/j.ecoenv.2017.10.064. Epub 2017 Nov 9.


Impact of experience on self-assessment accuracy of clinical colonoscopy competence.

Scaffidi MA, Grover SC, Carnahan H, Khan R, Amadio JM, Yu JJ, Dargavel C, Khanna N, Ling SC, Yong E, Nguyen GC, Walsh CM.

Gastrointest Endosc. 2018 Mar;87(3):827-836.e2. doi: 10.1016/j.gie.2017.10.040. Epub 2017 Nov 6.


Dietary zinc addition influenced zinc and lipid deposition in the fore- and mid-intestine of juvenile yellow catfish Pelteobagrus fulvidraco.

Chen GH, Hogstrand C, Luo Z, Zhang DG, Ling SC, Wu K.

Br J Nutr. 2017 Oct;118(8):570-579. doi: 10.1017/S0007114517002446. Epub 2017 Sep 26.


A prospective comparison of live and video-based assessments of colonoscopy performance.

Scaffidi MA, Grover SC, Carnahan H, Yu JJ, Yong E, Nguyen GC, Ling SC, Khanna N, Walsh CM.

Gastrointest Endosc. 2018 Mar;87(3):766-775. doi: 10.1016/j.gie.2017.08.020. Epub 2017 Aug 30.


Cystic Fibrosis-related Liver Disease: Research Challenges and Future Perspectives.

Debray D, Narkewicz MR, Bodewes FAJA, Colombo C, Housset C, de Jonge HR, Jonker JW, Kelly DA, Ling SC, Poynard T, Sogni P, Trauner M, Witters P, Baumann U, Wilschanski M, Verkade HJ.

J Pediatr Gastroenterol Nutr. 2017 Oct;65(4):443-448. doi: 10.1097/MPG.0000000000001676.


Splanchnic, Thoracoabdominal, and Cerebral Blood Flow Volumes in Healthy Children and Young Adults in Fasting and Postprandial States: Determining Reference Ranges by Using Phase-Contrast MR Imaging.

Muthusami P, Yoo SJ, Chaturvedi R, Gill N, Windram J, Schantz D, Prsa M, Caro-Dominguez P, Seed M, Grosse-Wortmann L, Ling SC, Chavhan GB.

Radiology. 2017 Oct;285(1):231-241. doi: 10.1148/radiol.2017162114. Epub 2017 May 22.


The Highs and Lows of Fetal Programming for Fatty Liver Disease.

Mouzaki M, Ling SC.

J Pediatr. 2017 Aug;187:13-15. doi: 10.1016/j.jpeds.2017.03.062. Epub 2017 May 5. No abstract available.


Platelet count, spleen length, and platelet count-to-spleen length ratio for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis.

Colli A, Gana JC, Yap J, Adams-Webber T, Rashkovan N, Ling SC, Casazza G.

Cochrane Database Syst Rev. 2017 Apr 26;4:CD008759. doi: 10.1002/14651858.CD008759.pub2. Review.


Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.

Ditsworth D, Maldonado M, McAlonis-Downes M, Sun S, Seelman A, Drenner K, Arnold E, Ling SC, Pizzo D, Ravits J, Cleveland DW, Da Cruz S.

Acta Neuropathol. 2017 Jun;133(6):907-922. doi: 10.1007/s00401-017-1698-6. Epub 2017 Mar 29.


Management of Pediatric Nonalcoholic Fatty Liver Disease by Academic Hepatologists in Canada: A Nationwide Survey.

Mouzaki M, Ling SC, Schreiber RA, Kamath BM.

J Pediatr Gastroenterol Nutr. 2017 Oct;65(4):380-383. doi: 10.1097/MPG.0000000000001581.


A national retrospective study of paediatric end-stage liver disease as a predictor of change to second-line therapy in children with autoimmune hepatitis.

Zizzo AN, Jimenez-Rivera C, Kim J, Schreiber RA, Ling SC, Yap J, Critch J, Ahmed N, Alvarez F, Kamath BM; Canadian Paediatric Hepatology Research Group (CPHRG).

Liver Int. 2017 Oct;37(10):1562-1570. doi: 10.1111/liv.13387. Epub 2017 Mar 15.


Health-related Quality of Life in Pediatric Patients With Chronic Hepatitis B Living in the United States and Canada.

Schwarzenberg SJ, Ling SC, Cloonan YK, Lin HS, Evon DM, Murray KF, Rodriguez-Baez N, Rosenthal P, Teckman J, Schwarz KB; Hepatitis B Research Network.

J Pediatr Gastroenterol Nutr. 2017 May;64(5):760-769. doi: 10.1097/MPG.0000000000001525.


Early Posthepatoportoenterostomy Predictors of Native Liver Survival in Biliary Atresia.

Nightingale S, Stormon MO, O'Loughlin EV, Shun A, Thomas G, Benchimol EI, Day AS, Adams S, Shi E, Ooi CY, Kamath BM, Fecteau A, Langer JC, Roberts EA, Ling SC, Ng VL.

J Pediatr Gastroenterol Nutr. 2017 Feb;64(2):203-209. doi: 10.1097/MPG.0000000000001289.


Hepatoblastoma in Explanted Livers of Patients With Biliary Atresia.

Amir AZ, Sharma A, Cutz E, Avitzur Y, Shaikh F, Kamath BM, Ling SC, Ghanekar A, Ng VL.

J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):188-94. doi: 10.1097/MPG.0000000000001167.


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