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Alginate/Chitosan microparticles for gastric passage and intestinal release of therapeutic protein nanoparticles.

Ling K, Wu H, Neish AS, Champion JA.

J Control Release. 2018 Dec 14. pii: S0168-3659(18)30720-X. doi: 10.1016/j.jconrel.2018.12.017. [Epub ahead of print]


Use of commercially available sodium hyaluronate 0.18% eye drops for corneal epithelial healing in diabetic patients.

Ling K, Bastion MC.

Int Ophthalmol. 2018 Dec 7. doi: 10.1007/s10792-018-1057-1. [Epub ahead of print]


A review of vedolizumab and ustekinumab for the treatment of inflammatory bowel diseases.

Shim HH, Chan PW, Chuah SW, Schwender BJ, Kong SC, Ling KL.

JGH Open. 2018 Jun 20;2(5):223-234. doi: 10.1002/jgh3.12065. eCollection 2018 Oct. Review.


Elucidating the Interaction of CF Airway Epithelial Cells and Rhinovirus: Using the Host-Pathogen Relationship to Identify Future Therapeutic Strategies.

Ling KM, Garratt LW, Lassmann T, Stick SM, Kicic A; WAERP; AusREC; Australian Respiratory Early Surveillance Team for Cystic Fibrosis.

Front Pharmacol. 2018 Nov 7;9:1270. doi: 10.3389/fphar.2018.01270. eCollection 2018. Review.


Multiplexed determination of intracellular messenger RNA by using a graphene oxide nanoprobe modified with target-recognizing fluorescent oligonucleotides.

Jiang H, Li FR, Li W, Lu X, Ling K.

Mikrochim Acta. 2018 Nov 15;185(12):552. doi: 10.1007/s00604-018-3090-1.


Evaluation of the bioactivity about anti-sca-1/basic fibroblast growth factor-urinary bladder matrix scaffold for pelvic reconstruction.

Li J, Chen X, Ling K, Liang Z, Xu H.

J Biomater Appl. 2018 Nov 14:885328218811390. doi: 10.1177/0885328218811390. [Epub ahead of print]


Masking of myocardial infarction ECG in a patient with Wolff-Parkinson-White syndrome.

Ling KH, Ng KS.

Singapore Med J. 2018 Oct;59(10):558-559. doi: 10.11622/smedj.2018130. No abstract available.


Antitumor effects of berberine against EGFR, ERK1/2, P38 and AKT in MDA-MB231 and MCF-7 breast cancer cells using molecular modelling and in vitro study.

Jabbarzadeh Kaboli P, Leong MP, Ismail P, Ling KH.

Pharmacol Rep. 2018 Aug 1;71(1):13-23. doi: 10.1016/j.pharep.2018.07.005. [Epub ahead of print]


Cucurbit Genomics Database (CuGenDB): a central portal for comparative and functional genomics of cucurbit crops.

Zheng Y, Wu S, Bai Y, Sun H, Jiao C, Guo S, Zhao K, Blanca J, Zhang Z, Huang S, Xu Y, Weng Y, Mazourek M, K Reddy U, Ando K, McCreight JD, Schaffer AA, Burger J, Tadmor Y, Katzir N, Tang X, Liu Y, Giovannoni JJ, Ling KS, Wechter WP, Levi A, Garcia-Mas J, Grumet R, Fei Z.

Nucleic Acids Res. 2018 Oct 13. doi: 10.1093/nar/gky944. [Epub ahead of print]


Fungal prostatic abscess erupting through the penis.

Kam J, Ling KY, Jeffery N, Arianayagam M, Winter M.

Br J Hosp Med (Lond). 2018 Oct 2;79(10):592. doi: 10.12968/hmed.2018.79.10.592. No abstract available.


Reversible Ultralong Organic Phosphorescence for Visual and Selective Chloroform Detection.

Wu Q, Ma H, Ling K, Gan N, Cheng Z, Gu L, Cai S, An Z, Shi H, Huang W.

ACS Appl Mater Interfaces. 2018 Oct 3;10(39):33730-33736. doi: 10.1021/acsami.8b13713. Epub 2018 Sep 24.


Population Density and Risk of Inflammatory Bowel Disease: A Prospective Population-Based Study in 13 Countries or Regions in Asia-Pacific.

Ng SC, Kaplan GG, Tang W, Banerjee R, Adigopula B, Underwood FE, Tanyingoh D, Wei SC, Lin WC, Lin HH, Li J, Bell S, Niewiadomski O, Kamm MA, Zeng Z, Chen M, Hu P, Ong D, Ooi CJ, Ling KL, Miao Y, Miao J, de Silva HJ, Niriella M, Aniwan S, Limsrivilai J, Pisespongsa P, Wu K, Yang H, Ng KK, Yu HH, Wang Y, Ouyang Q, Abdullah M, Simadibrata M, Gunawan J, Hilmi I, Goh KL, Cao Q, Sheng H, Ong-Go A, Chong VH, Ching JYL, Wu JCY, Chan FKL, Sung JJY.

Am J Gastroenterol. 2018 Sep 3. doi: 10.1038/s41395-018-0233-2. [Epub ahead of print]


Mycobacterium abscessus Infection During Ustekinumab Treatment in Crohn's Disease: A Case Report and Review of the Literature.

Shim HH, Cai SCS, Chan W, Low JGH, Tan HH, Ling KL.

J Crohns Colitis. 2018 Nov 28;12(12):1505-1507. doi: 10.1093/ecco-jcc/jjy126.


Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules.

He K, Ma X, Xu T, Li Y, Hodge A, Zhang Q, Torline J, Huang Y, Zhao J, Ling K, Hu J.

Nat Commun. 2018 Aug 17;9(1):3310. doi: 10.1038/s41467-018-05867-1.


Synthesis and Reactivity of N-Allenyl Cyanamides.

Ayres JN, Williams MTJ, Tizzard GJ, Coles SJ, Ling KB, Morrill LC.

Org Lett. 2018 Sep 7;20(17):5282-5285. doi: 10.1021/acs.orglett.8b02225. Epub 2018 Aug 14.


Simultaneously Enhancing Efficiency and Lifetime of Ultralong Organic Phosphorescence Materials by Molecular Self-Assembly.

Bian L, Shi H, Wang X, Ling K, Ma H, Li M, Cheng Z, Ma C, Cai S, Wu Q, Gan N, Xu X, An Z, Huang W.

J Am Chem Soc. 2018 Aug 29;140(34):10734-10739. doi: 10.1021/jacs.8b03867. Epub 2018 Aug 16.


The HOPES Registry - Houston Methodist Hospital Outcomes-based Prospective Endpoints in Stroke.

Gadhia R, McCane D, Lee J, Ling KC, Jiang K, Chiu D.

J Stroke Cerebrovasc Dis. 2018 Nov;27(11):2973-2976. doi: 10.1016/j.jstrokecerebrovasdis.2018.06.029. Epub 2018 Jul 30.


Quantitation of intracellular triphosphate metabolites of antiretroviral agents in peripheral blood mononuclear cells (PBMCs) and corresponding cell count determinations: review of current methods and challenges.

Xiao D, Ling KHJ, Custodio J, Majeed SR, Tarnowski T.

Expert Opin Drug Metab Toxicol. 2018 Aug;14(8):781-802. doi: 10.1080/17425255.2018.1500552. Epub 2018 Jul 25. Review.


Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model.

Bala U, Leong MP, Lim CL, Shahar HK, Othman F, Lai MI, Law ZK, Ramli K, Htwe O, Ling KH, Cheah PS.

PLoS One. 2018 May 24;13(5):e0197711. doi: 10.1371/journal.pone.0197711. eCollection 2018.


The fatty acid composition of Estonian and Latvian retail milk; implications for human nutrition compared with a designer milk.

Henno M, Ariko T, Kaart T, Kuusik S, Ling K, Kass M, Jaakson H, Leming R, Givens DI, Sterna V, Ots M.

J Dairy Res. 2018 May;85(2):247-250. doi: 10.1017/S0022029918000183.


Dynamic Ultralong Organic Phosphorescence by Photoactivation.

Gu L, Shi H, Gu M, Ling K, Ma H, Cai S, Song L, Ma C, Li H, Xing G, Hang X, Li J, Gao Y, Yao W, Shuai Z, An Z, Liu X, Huang W.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8425-8431. doi: 10.1002/anie.201712381. Epub 2018 Jun 10.


Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system.

Ling K, Jiang L, Liang S, Kwong J, Yang L, Li Y, PingYin, Deng Q, Liang Z.

J Ovarian Res. 2018 May 2;11(1):36. doi: 10.1186/s13048-018-0403-2.


Consensus and contentious statements on the use of probiotics in clinical practice: A south east Asian gastro-neuro motility association working team report.

Gwee KA, Lee WW, Ling KL, Ooi CJ, Quak SH, Dan YY, Siah KT, Huang JG, Chua ASB, Hilmi IN, Raja Ali RA, Ong C, Simadibrata M, Abdullah M, Sollano JD, Leelakusolvong S, Gonlachanvit S, Lee YY, Ricaforte-Campos JD, Yin YK, Chong KM, Wong CY.

J Gastroenterol Hepatol. 2018 Oct;33(10):1707-1716. doi: 10.1111/jgh.14268. Epub 2018 Jun 12. Review.


Molecular modeling, dynamics simulations, and binding efficiency of berberine derivatives: A new group of RAF inhibitors for cancer treatment.

Jabbarzadeh Kaboli P, Ismail P, Ling KH.

PLoS One. 2018 Mar 22;13(3):e0193941. doi: 10.1371/journal.pone.0193941. eCollection 2018.


Scalable total synthesis and comprehensive structure-activity relationship studies of the phytotoxin coronatine.

Littleson MM, Baker CM, Dalençon AJ, Frye EC, Jamieson C, Kennedy AR, Ling KB, McLachlan MM, Montgomery MG, Russell CJ, Watson AJB.

Nat Commun. 2018 Mar 16;9(1):1105. doi: 10.1038/s41467-018-03443-1.


Drug-Drug Interaction Studies Between Hepatitis C Virus Antivirals Sofosbuvir/Velpatasvir and Boosted and Unboosted Human Immunodeficiency Virus Antiretroviral Regimens in Healthy Volunteers.

Mogalian E, Stamm LM, Osinusi A, Brainard DM, Shen G, Ling KHJ, Mathias A.

Clin Infect Dis. 2018 Aug 31;67(6):934-940. doi: 10.1093/cid/ciy201.


Pharmacokinetics and Safety of Velpatasvir and Sofosbuvir/Velpatasvir in Subjects with Hepatic Impairment.

Mogalian E, Brainard DM, Osinusi A, Moorehead L, Murray B, Ling KHJ, Perry R, Curtis C, Lawitz E, Lasseter K, Marbury T, Mathias A.

Clin Pharmacokinet. 2018 Nov;57(11):1449-1457. doi: 10.1007/s40262-018-0645-6.


Antisense-mediated reduction of EphA4 in the adult CNS does not improve the function of mice with amyotrophic lateral sclerosis.

Ling KK, Jackson M, Alkam D, Liu D, Allaire N, Sun C, Kiaei M, McCampbell A, Rigo F.

Neurobiol Dis. 2018 Jun;114:174-183. doi: 10.1016/j.nbd.2018.03.002. Epub 2018 Mar 6.


Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells.

Buckley AG, Looi K, Iosifidis T, Ling KM, Sutanto EN, Martinovich KM, Kicic-Starcevich E, Garratt LW, Shaw NC, Lannigan FJ, Larcombe AN, Zosky G, Knight DA, Rigby PJ, Kicic A, Stick SM.

Biol Proced Online. 2018 Feb 1;20:3. doi: 10.1186/s12575-018-0070-0. eCollection 2018.


Hydrogen-Bonded Organic Aromatic Frameworks for Ultralong Phosphorescence by Intralayer π-π Interactions.

Cai S, Shi H, Zhang Z, Wang X, Ma H, Gan N, Wu Q, Cheng Z, Ling K, Gu M, Ma C, Gu L, An Z, Huang W.

Angew Chem Int Ed Engl. 2018 Apr 3;57(15):4005-4009. doi: 10.1002/anie.201800697. Epub 2018 Mar 7.


Direct chemiluminescence detection of circulating microRNAs in serum samples using a single-strand specific nuclease-distinguishing nucleic acid hybrid system.

Ling K, Jiang H, Huang X, Li Y, Lin J, Li FR.

Chem Commun (Camb). 2018 Feb 15;54(15):1909-1912. doi: 10.1039/c7cc09087k.


Influence of functional food components on gut health.

Wan MLY, Ling KH, El-Nezami H, Wang MF.

Crit Rev Food Sci Nutr. 2018 Jan 30:1-10. doi: 10.1080/10408398.2018.1433629. [Epub ahead of print]


Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics.

Jones AC, Troy NM, White E, Hollams EM, Gout AM, Ling KM, Kicic A, Stick SM, Sly PD, Holt PG, Hall GL, Bosco A.

Sci Rep. 2018 Jan 24;8(1):1511. doi: 10.1038/s41598-018-19837-6.

Free PMC Article

Effects of human rhinovirus on epithelial barrier integrity and function in children with asthma.

Looi K, Buckley AG, Rigby PJ, Garratt LW, Iosifidis T, Zosky GR, Larcombe AN, Lannigan FJ, Ling KM, Martinovich KM, Kicic-Starcevich E, Shaw NC, Sutanto EN, Knight DA, Kicic A, Stick SM.

Clin Exp Allergy. 2018 May;48(5):513-524. doi: 10.1111/cea.13097. Epub 2018 Feb 20.


Reverse transcription loop-mediated isothermal amplification for species-specific detection of tomato chlorotic spot orthotospovirus.

Sui X, Zhang S, Wu Z, Ling KS.

J Virol Methods. 2018 Mar;253:56-60. doi: 10.1016/j.jviromet.2018.01.002. Epub 2018 Jan 12.


Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.

Huang KK, Ramnarayanan K, Zhu F, Srivastava S, Xu C, Tan ALK, Lee M, Tay S, Das K, Xing M, Fatehullah A, Alkaff SMF, Lim TKH, Lee J, Ho KY, Rozen SG, Teh BT, Barker N, Chia CK, Khor C, Ooi CJ, Fock KM, So J, Lim WC, Ling KL, Ang TL, Wong A, Rao J, Rajnakova A, Lim LG, Yap WM, Teh M, Yeoh KG, Tan P.

Cancer Cell. 2018 Jan 8;33(1):137-150.e5. doi: 10.1016/j.ccell.2017.11.018. Epub 2017 Dec 28.


Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics.

Martinovich KM, Iosifidis T, Buckley AG, Looi K, Ling KM, Sutanto EN, Kicic-Starcevich E, Garratt LW, Shaw NC, Montgomery S, Lannigan FJ, Knight DA, Kicic A, Stick SM.

Sci Rep. 2017 Dec 21;7(1):17971. doi: 10.1038/s41598-017-17952-4.


Predictive role of NUDT15 variants on thiopurine-induced myelotoxicity in Asian inflammatory bowel disease patients.

Sutiman N, Chen S, Ling KL, Chuah SW, Leong WF, Nadiger V, Tjai M, Choon Kong CS, Schwender BJ, Chan W, Shim HH, Lim WC, Khor CC, Cheung YB, Chowbay B.

Pharmacogenomics. 2018 Jan;19(1):31-43. doi: 10.2217/pgs-2017-0147. Epub 2017 Dec 6.


Adipose tissue insulin receptor and glucose transporter 4 expression, and blood glucose and insulin responses during glucose tolerance tests in transition Holstein cows with different body condition.

Jaakson H, Karis P, Ling K, Ilves-Luht A, Samarütel J, Henno M, Jõudu I, Waldmann A, Reimann E, Pärn P, Bruckmaier RM, Gross JJ, Kaart T, Kass M, Ots M.

J Dairy Sci. 2018 Jan;101(1):752-766. doi: 10.3168/jds.2017-12877. Epub 2017 Nov 6.


Comparative transcriptome analysis reveals networks of genes activated in the whitefly, Bemisia tabaci when fed on tomato plants infected with Tomato yellow leaf curl virus.

Hasegawa DK, Chen W, Zheng Y, Kaur N, Wintermantel WM, Simmons AM, Fei Z, Ling KS.

Virology. 2018 Jan 1;513:52-64. doi: 10.1016/j.virol.2017.10.008. Epub 2017 Oct 13.


Distributed State Estimation Using a Modified Partitioned Moving Horizon Strategy for Power Systems.

Chen T, Foo YSE, Ling KV, Chen X.

Sensors (Basel). 2017 Oct 11;17(10). pii: E2310. doi: 10.3390/s17102310.


The Origin of Chalcogen-Bonding Interactions.

Pascoe DJ, Ling KB, Cockroft SL.

J Am Chem Soc. 2017 Oct 25;139(42):15160-15167. doi: 10.1021/jacs.7b08511. Epub 2017 Oct 17.


Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs.

Kaboli PJ, Bazrafkan M, Ismail P, Ling KH.

Recent Pat Anticancer Drug Discov. 2017 Nov 20;12(4):384-400. doi: 10.2174/1574892812666170929131247.


The bottle gourd genome provides insights into Cucurbitaceae evolution and facilitates mapping of a Papaya ring-spot virus resistance locus.

Wu S, Shamimuzzaman M, Sun H, Salse J, Sui X, Wilder A, Wu Z, Levi A, Xu Y, Ling KS, Fei Z.

Plant J. 2017 Dec;92(5):963-975. doi: 10.1111/tpj.13722. Epub 2017 Nov 12.


EpCAM aptamer-functionalized polydopamine-coated mesoporous silica nanoparticles loaded with DM1 for targeted therapy in colorectal cancer.

Li Y, Duo Y, Bao S, He L, Ling K, Luo J, Zhang Y, Huang H, Zhang H, Yu X.

Int J Nanomedicine. 2017 Aug 26;12:6239-6257. doi: 10.2147/IJN.S143293. eCollection 2017.


Carbon Monoxide and Its Controlled Release: Therapeutic Application, Detection, and Development of Carbon Monoxide Releasing Molecules (CORMs).

Ling K, Men F, Wang WC, Zhou YQ, Zhang HW, Ye DW.

J Med Chem. 2018 Apr 12;61(7):2611-2635. doi: 10.1021/acs.jmedchem.6b01153. Epub 2017 Sep 20.


Bioengineering Bacterially Derived Immunomodulants: A Therapeutic Approach to Inflammatory Bowel Disease.

Herrera Estrada L, Wu H, Ling K, Zhang G, Sumagin R, Parkos CA, Jones RM, Champion JA, Neish AS.

ACS Nano. 2017 Oct 24;11(10):9650-9662. doi: 10.1021/acsnano.7b03239. Epub 2017 Sep 5.


Novosphingobium clariflavum sp. nov., isolated from a household product plant.

Zhang X, Liu Y, Lin Y, Wang L, Yao S, Cao Y, Zhai L, Tang X, Zhang L, Zhang T, Ge Y, Ling K, Liu J, Cheng C.

Int J Syst Evol Microbiol. 2017 Sep;67(9):3150-3155. doi: 10.1099/ijsem.0.001803. Epub 2017 Aug 25.


Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrity.

Gorman S, Buckley AG, Ling KM, Berry LJ, Fear VS, Stick SM, Larcombe AN, Kicic A, Hart PH.

Physiol Rep. 2017 Aug;5(15). pii: e13371. doi: 10.14814/phy2.13371.

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