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Items: 1 to 50 of 359

1.

Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers.

Miskinyte G, Grønning Hansen M, Monni E, Lam M, Bengzon J, Lindvall O, Ahlenius H, Kokaia Z.

PLoS One. 2018 Oct 11;13(10):e0204688. doi: 10.1371/journal.pone.0204688. eCollection 2018.

2.

Sensors of Succinate: Neural Stem Cell Grafts Fight Neuroinflammation.

Kokaia Z, Lindvall O.

Cell Stem Cell. 2018 Mar 1;22(3):283-285. doi: 10.1016/j.stem.2018.01.019.

PMID:
29499143
3.

Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors.

Laterza C, Uoshima N, Tornero D, Wilhelmsson U, Stokowska A, Ge R, Pekny M, Lindvall O, Kokaia Z.

PLoS One. 2018 Feb 5;13(2):e0192118. doi: 10.1371/journal.pone.0192118. eCollection 2018.

4.

Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks.

Miskinyte G, Devaraju K, Grønning Hansen M, Monni E, Tornero D, Woods NB, Bengzon J, Ahlenius H, Lindvall O, Kokaia Z.

Stem Cell Res Ther. 2017 Sep 29;8(1):207. doi: 10.1186/s13287-017-0658-3.

5.

Choroid plexus-cerebrospinal fluid route for monocyte-derived macrophages after stroke.

Ge R, Tornero D, Hirota M, Monni E, Laterza C, Lindvall O, Kokaia Z.

J Neuroinflammation. 2017 Jul 28;14(1):153. doi: 10.1186/s12974-017-0909-3.

6.

Monocyte depletion early after stroke promotes neurogenesis from endogenous neural stem cells in adult brain.

Laterza C, Wattananit S, Uoshima N, Ge R, Pekny R, Tornero D, Monni E, Lindvall O, Kokaia Z.

Exp Neurol. 2017 Nov;297:129-137. doi: 10.1016/j.expneurol.2017.07.012. Epub 2017 Jul 23.

PMID:
28746827
7.

Transplantation of reprogrammed neurons for improved recovery after stroke.

Kokaia Z, Tornero D, Lindvall O.

Prog Brain Res. 2017;231:245-263. doi: 10.1016/bs.pbr.2016.11.013. Epub 2017 Jan 6. Review.

PMID:
28554399
8.

Replacing Dopamine Neurons in Parkinson's Disease: How did it happen?

Björklund A, Lindvall O.

J Parkinsons Dis. 2017;7(s1):S21-S31. doi: 10.3233/JPD-179002.

9.

Stroke alters behavior of human skin-derived neural progenitors after transplantation adjacent to neurogenic area in rat brain.

de la Rosa-Prieto C, Laterza C, Gonzalez-Ramos A, Wattananit S, Ge R, Lindvall O, Tornero D, Kokaia Z.

Stem Cell Res Ther. 2017 Mar 9;8(1):59. doi: 10.1186/s13287-017-0513-6.

10.

Spontaneous Recovery of Upper Extremity Motor Impairment After Ischemic Stroke: Implications for Stem Cell-Based Therapeutic Approaches.

Delavaran H, Aked J, Sjunnesson H, Lindvall O, Norrving B, Kokaia Z, Lindgren A.

Transl Stroke Res. 2017 Aug;8(4):351-361. doi: 10.1007/s12975-017-0523-9. Epub 2017 Feb 15.

11.

Attitudes to Stem Cell Therapy Among Ischemic Stroke Survivors in the Lund Stroke Recovery Study.

Aked J, Delavaran H, Lindvall O, Norrving B, Kokaia Z, Lindgren A.

Stem Cells Dev. 2017 Apr 15;26(8):566-572. doi: 10.1089/scd.2016.0343. Epub 2017 Feb 28.

PMID:
28142330
12.

Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli.

Tornero D, Tsupykov O, Granmo M, Rodriguez C, Grønning-Hansen M, Thelin J, Smozhanik E, Laterza C, Wattananit S, Ge R, Tatarishvili J, Grealish S, Brüstle O, Skibo G, Parmar M, Schouenborg J, Lindvall O, Kokaia Z.

Brain. 2017 Mar 1;140(3):692-706. doi: 10.1093/brain/aww347.

PMID:
28115364
13.

Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.

Li W, Englund E, Widner H, Mattsson B, van Westen D, Lätt J, Rehncrona S, Brundin P, Björklund A, Lindvall O, Li JY.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6544-9. doi: 10.1073/pnas.1605245113. Epub 2016 May 2.

14.

Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice.

Wattananit S, Tornero D, Graubardt N, Memanishvili T, Monni E, Tatarishvili J, Miskinyte G, Ge R, Ahlenius H, Lindvall O, Schwartz M, Kokaia Z.

J Neurosci. 2016 Apr 13;36(15):4182-95. doi: 10.1523/JNEUROSCI.4317-15.2016.

15.

Neurogenesis following Stroke Affecting the Adult Brain.

Lindvall O, Kokaia Z.

Cold Spring Harb Perspect Biol. 2015 Nov 2;7(11). pii: a019034. doi: 10.1101/cshperspect.a019034. Review.

16.

Treatment of Parkinson's disease using cell transplantation.

Lindvall O.

Philos Trans R Soc Lond B Biol Sci. 2015 Oct 19;370(1680):20140370. doi: 10.1098/rstb.2014.0370. Review.

17.

Clinical translation of stem cell transplantation in Parkinson's disease.

Lindvall O.

J Intern Med. 2016 Jan;279(1):30-40. doi: 10.1111/joim.12415. Epub 2015 Aug 31. Review.

18.

Inflammation without neuronal death triggers striatal neurogenesis comparable to stroke.

Chapman KZ, Ge R, Monni E, Tatarishvili J, Ahlenius H, Arvidsson A, Ekdahl CT, Lindvall O, Kokaia Z.

Neurobiol Dis. 2015 Nov;83:1-15. doi: 10.1016/j.nbd.2015.08.013. Epub 2015 Aug 20.

PMID:
26299391
19.

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse.

Magnusson JP, Göritz C, Tatarishvili J, Dias DO, Smith EM, Lindvall O, Kokaia Z, Frisén J.

Science. 2014 Oct 10;346(6206):237-41. doi: 10.1126/science.346.6206.237. Epub 2014 Oct 9.

20.

Human induced pluripotent stem cells improve recovery in stroke-injured aged rats.

Tatarishvili J, Oki K, Monni E, Koch P, Memanishvili T, Buga AM, Verma V, Popa-Wagner A, Brüstle O, Lindvall O, Kokaia Z.

Restor Neurol Neurosci. 2014;32(4):547-58. doi: 10.3233/RNN-140404.

PMID:
24916776
21.

The age and genomic integrity of neurons after cortical stroke in humans.

Huttner HB, Bergmann O, Salehpour M, Rácz A, Tatarishvili J, Lindgren E, Csonka T, Csiba L, Hortobágyi T, Méhes G, Englund E, Solnestam BW, Zdunek S, Scharenberg C, Ström L, Ståhl P, Sigurgeirsson B, Dahl A, Schwab S, Possnert G, Bernard S, Kokaia Z, Lindvall O, Lundeberg J, Frisén J.

Nat Neurosci. 2014 Jun;17(6):801-3. doi: 10.1038/nn.3706. Epub 2014 Apr 20.

PMID:
24747576
22.

Human fetal striatum-derived neural stem (NS) cells differentiate to mature neurons in vitro and in vivo.

Monni E, Cusulin C, Cavallaro M, Lindvall O, Kokaia Z.

Curr Stem Cell Res Ther. 2014;9(4):338-46.

PMID:
24654649
23.

Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports.

Kefalopoulou Z, Politis M, Piccini P, Mencacci N, Bhatia K, Jahanshahi M, Widner H, Rehncrona S, Brundin P, Björklund A, Lindvall O, Limousin P, Quinn N, Foltynie T.

JAMA Neurol. 2014 Jan;71(1):83-7. doi: 10.1001/jamaneurol.2013.4749.

24.

Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery.

Tornero D, Wattananit S, Grønning Madsen M, Koch P, Wood J, Tatarishvili J, Mine Y, Ge R, Monni E, Devaraju K, Hevner RF, Brüstle O, Lindvall O, Kokaia Z.

Brain. 2013 Dec;136(Pt 12):3561-77. doi: 10.1093/brain/awt278. Epub 2013 Oct 21.

PMID:
24148272
25.

FoxJ1-expressing cells contribute to neurogenesis in forebrain of adult rats: evidence from in vivo electroporation combined with piggyBac transposon.

Devaraju K, Barnabé-Heider F, Kokaia Z, Lindvall O.

Exp Cell Res. 2013 Nov 1;319(18):2790-800. doi: 10.1016/j.yexcr.2013.08.028. Epub 2013 Sep 25.

PMID:
24075965
26.

Regulation of stem cell therapies under attack in Europe: for whom the bell tolls.

Bianco P, Barker R, Brüstle O, Cattaneo E, Clevers H, Daley GQ, De Luca M, Goldstein L, Lindvall O, Mummery C, Robey PG, Sattler de Sousa E Brito C, Smith A.

EMBO J. 2013 May 29;32(11):1489-95. doi: 10.1038/emboj.2013.114. Epub 2013 May 3.

27.

Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9.

Åkerblom M, Sachdeva R, Quintino L, Wettergren EE, Chapman KZ, Manfre G, Lindvall O, Lundberg C, Jakobsson J.

Nat Commun. 2013;4:1770. doi: 10.1038/ncomms2801.

PMID:
23612311
28.

Developing dopaminergic cell therapy for Parkinson's disease--give up or move forward?

Lindvall O.

Mov Disord. 2013 Mar;28(3):268-73. doi: 10.1002/mds.25378. Epub 2013 Feb 11. Review.

PMID:
23401015
29.

Grafted human neural stem cells enhance several steps of endogenous neurogenesis and improve behavioral recovery after middle cerebral artery occlusion in rats.

Mine Y, Tatarishvili J, Oki K, Monni E, Kokaia Z, Lindvall O.

Neurobiol Dis. 2013 Apr;52:191-203. doi: 10.1016/j.nbd.2012.12.006. Epub 2012 Dec 28.

PMID:
23276704
30.

Stem cell repair of striatal ischemia.

Kokaia Z, Lindvall O.

Prog Brain Res. 2012;201:35-53. doi: 10.1016/B978-0-444-59544-7.00003-2. Review.

PMID:
23186709
31.

Proximity of brain infarcts to regions of endogenous neurogenesis and involvement of striatum in ischaemic stroke.

Delavaran H, Sjunnesson H, Arvidsson A, Lindvall O, Norrving B, van Westen D, Kokaia Z, Lindgren A.

Eur J Neurol. 2013 Mar;20(3):473-9. doi: 10.1111/j.1468-1331.2012.03877.x. Epub 2012 Oct 11.

PMID:
23057628
32.

Embryonic stem cell-derived neural stem cells fuse with microglia and mature neurons.

Cusulin C, Monni E, Ahlenius H, Wood J, Brune JC, Lindvall O, Kokaia Z.

Stem Cells. 2012 Dec;30(12):2657-71. doi: 10.1002/stem.1227.

33.

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens.

Ribeiro D, Laguna Goya R, Ravindran G, Vuono R, Parish CL, Foldi C, Piroth T, Yang S, Parmar M, Nikkhah G, Hjerling-Leffler J, Lindvall O, Barker RA, Arenas E.

Neurobiol Dis. 2013 Jan;49:118-27. doi: 10.1016/j.nbd.2012.08.006. Epub 2012 Aug 24.

PMID:
22940632
34.

Cross-talk between neural stem cells and immune cells: the key to better brain repair?

Kokaia Z, Martino G, Schwartz M, Lindvall O.

Nat Neurosci. 2012 Jul 26;15(8):1078-87. doi: 10.1038/nn.3163. Review.

PMID:
22837038
35.

Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions.

Kirkeby A, Grealish S, Wolf DA, Nelander J, Wood J, Lundblad M, Lindvall O, Parmar M.

Cell Rep. 2012 Jun 28;1(6):703-14. doi: 10.1016/j.celrep.2012.04.009. Epub 2012 May 26.

36.

Why is it taking so long to develop clinically competitive stem cell therapies for CNS disorders?

Lindvall O.

Cell Stem Cell. 2012 Jun 14;10(6):660-662. doi: 10.1016/j.stem.2012.04.004.

37.

Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease.

Biscaro B, Lindvall O, Tesco G, Ekdahl CT, Nitsch RM.

Neurodegener Dis. 2012;9(4):187-98. doi: 10.1159/000330363. Epub 2012 May 8.

38.

Societal value of stem cell therapy in stroke--a modeling study.

Svensson J, Ghatnekar O, Lindgren A, Lindvall O, Norrving B, Persson U, Kokaia Z.

Cerebrovasc Dis. 2012;33(6):532-9. doi: 10.1159/000337765. Epub 2012 May 9.

39.

Altered synaptic properties during integration of adult-born hippocampal neurons following a seizure insult.

Jackson J, Chugh D, Nilsson P, Wood J, Carlström K, Lindvall O, Ekdahl CT.

PLoS One. 2012;7(4):e35557. doi: 10.1371/journal.pone.0035557. Epub 2012 Apr 23.

40.

Translating research into therapies.

Glimcher LH, Lindvall O, Aguirre V, Topalian SL, Musunuru K, Fauci AS.

Cell. 2012 Mar 16;148(6):1077-8. No abstract available.

41.

Ectopic ependymal cells in striatum accompany neurogenesis in a rat model of stroke.

Danilov AI, Kokaia Z, Lindvall O.

Neuroscience. 2012 Jul 12;214:159-70. doi: 10.1016/j.neuroscience.2012.03.062. Epub 2012 Apr 21.

PMID:
22531371
42.

Adaptor protein LNK is a negative regulator of brain neural stem cell proliferation after stroke.

Ahlenius H, Devaraju K, Monni E, Oki K, Wattananit S, Darsalia V, Iosif RE, Torper O, Wood JC, Braun S, Jagemann L, Nuber UA, Englund E, Jacobsen SE, Lindvall O, Kokaia Z.

J Neurosci. 2012 Apr 11;32(15):5151-64. doi: 10.1523/JNEUROSCI.0474-12.2012.

43.

Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain.

Oki K, Tatarishvili J, Wood J, Koch P, Wattananit S, Mine Y, Monni E, Tornero D, Ahlenius H, Ladewig J, Brüstle O, Lindvall O, Kokaia Z.

Stem Cells. 2012 Jun;30(6):1120-33. doi: 10.1002/stem.1104.

44.

Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts.

Politis M, Wu K, Loane C, Quinn NP, Brooks DJ, Oertel WH, Björklund A, Lindvall O, Piccini P.

Sci Transl Med. 2012 Apr 4;4(128):128ra41. doi: 10.1126/scitranslmed.3003391.

45.

Clinical translation of stem cells in neurodegenerative disorders.

Lindvall O, Barker RA, Brüstle O, Isacson O, Svendsen CN.

Cell Stem Cell. 2012 Feb 3;10(2):151-5. doi: 10.1016/j.stem.2012.01.009.

46.

Dopaminergic neurons for Parkinson's therapy.

Lindvall O.

Nat Biotechnol. 2012 Jan 9;30(1):56-8. doi: 10.1038/nbt.2077. No abstract available.

PMID:
22231097
47.

Clinical application of stem cell therapy in Parkinson's disease.

Politis M, Lindvall O.

BMC Med. 2012 Jan 4;10:1. doi: 10.1186/1741-7015-10-1. Review.

48.

Meteorin is a chemokinetic factor in neuroblast migration and promotes stroke-induced striatal neurogenesis.

Wang Z, Andrade N, Torp M, Wattananit S, Arvidsson A, Kokaia Z, Jørgensen JR, Lindvall O.

J Cereb Blood Flow Metab. 2012 Feb;32(2):387-98. doi: 10.1038/jcbfm.2011.156. Epub 2011 Nov 2.

49.

Cometin is a novel neurotrophic factor that promotes neurite outgrowth and neuroblast migration in vitro and supports survival of spiral ganglion neurons in vivo.

Jørgensen JR, Fransson A, Fjord-Larsen L, Thompson LH, Houchins JP, Andrade N, Torp M, Kalkkinen N, Andersson E, Lindvall O, Ulfendahl M, Brunak S, Johansen TE, Wahlberg LU.

Exp Neurol. 2012 Jan;233(1):172-81. doi: 10.1016/j.expneurol.2011.09.027. Epub 2011 Oct 2.

50.

Efficient induction of functional neurons from adult human fibroblasts.

Pfisterer U, Wood J, Nihlberg K, Hallgren O, Bjermer L, Westergren-Thorsson G, Lindvall O, Parmar M.

Cell Cycle. 2011 Oct 1;10(19):3311-6. doi: 10.4161/cc.10.19.17584. Epub 2011 Oct 1.

PMID:
21934358

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