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Items: 18


Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system.

Rutledge EA, Lindström NO, Michos O, McMahon AP.

Dev Biol. 2020 Feb 15;458(2):164-176. doi: 10.1016/j.ydbio.2019.11.007. Epub 2019 Nov 14.


Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney.

Ransick A, Lindström NO, Liu J, Zhu Q, Guo JJ, Alvarado GF, Kim AD, Black HG, Kim J, McMahon AP.

Dev Cell. 2019 Nov 4;51(3):399-413.e7. doi: 10.1016/j.devcel.2019.10.005.


In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes.

Tran T, Lindström NO, Ransick A, De Sena Brandine G, Guo Q, Kim AD, Der B, Peti-Peterdi J, Smith AD, Thornton M, Grubbs B, McMahon JA, McMahon AP.

Dev Cell. 2019 Jul 1;50(1):102-116.e6. doi: 10.1016/j.devcel.2019.06.001.


Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment.

O'Brien LL, Combes AN, Short KM, Lindström NO, Whitney PH, Cullen-McEwen LA, Ju A, Abdelhalim A, Michos O, Bertram JF, Smyth IM, Little MH, McMahon AP.

Elife. 2018 Dec 5;7. pii: e40392. doi: 10.7554/eLife.40392.


Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions.

Lindström NO, De Sena Brandine G, Ransick A, McMahon AP.

Am J Kidney Dis. 2019 Jan;73(1):140-142. doi: 10.1053/j.ajkd.2018.07.002. Epub 2018 Sep 18. No abstract available.


Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis.

Lindström NO, De Sena Brandine G, Tran T, Ransick A, Suh G, Guo J, Kim AD, Parvez RK, Ruffins SW, Rutledge EA, Thornton ME, Grubbs B, McMahon JA, Smith AD, McMahon AP.

Dev Cell. 2018 Jun 4;45(5):651-660.e4. doi: 10.1016/j.devcel.2018.05.010.


Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.

Lindström NO, McMahon JA, Guo J, Tran T, Guo Q, Rutledge E, Parvez RK, Saribekyan G, Schuler RE, Liao C, Kim AD, Abdelhalim A, Ruffins SW, Thornton ME, Baskin L, Grubbs B, Kesselman C, McMahon AP.

J Am Soc Nephrol. 2018 Mar;29(3):785-805. doi: 10.1681/ASN.2017080887. Epub 2018 Feb 15.


Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning.

Lindström NO, Tran T, Guo J, Rutledge E, Parvez RK, Thornton ME, Grubbs B, McMahon JA, McMahon AP.

J Am Soc Nephrol. 2018 Mar;29(3):825-840. doi: 10.1681/ASN.2017091036. Epub 2018 Feb 15.


Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney.

Lindström NO, Guo J, Kim AD, Tran T, Guo Q, De Sena Brandine G, Ransick A, Parvez RK, Thornton ME, Baskin L, Grubbs B, McMahon JA, Smith AD, McMahon AP.

J Am Soc Nephrol. 2018 Mar;29(3):806-824. doi: 10.1681/ASN.2017080890. Epub 2018 Feb 15.


The developmental and genetic basis of 'clubfoot' in the peroneal muscular atrophy mutant mouse.

Collinson JM, Lindström NO, Neves C, Wallace K, Meharg C, Charles RH, Ross ZK, Fraser AM, Mbogo I, Oras K, Nakamoto M, Barker S, Duce S, Miedzybrodzka Z, Vargesson N.

Development. 2018 Feb 8;145(3). pii: dev160093. doi: 10.1242/dev.160093.


Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice.

Berry RL, Ozdemir DD, Aronow B, Lindström NO, Dudnakova T, Thornburn A, Perry P, Baldock R, Armit C, Joshi A, Jeanpierre C, Shan J, Vainio S, Baily J, Brownstein D, Davies J, Hastie ND, Hohenstein P.

Dis Model Mech. 2015 Aug 1;8(8):903-17. doi: 10.1242/dmm.018523. Epub 2015 May 14.


The PI3K pathway balances self-renewal and differentiation of nephron progenitor cells through β-catenin signaling.

Lindström NO, Carragher NO, Hohenstein P.

Stem Cell Reports. 2015 Apr 14;4(4):551-60. doi: 10.1016/j.stemcr.2015.01.021. Epub 2015 Mar 5.


Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron.

Lindström NO, Lawrence ML, Burn SF, Johansson JA, Bakker ER, Ridgway RA, Chang CH, Karolak MJ, Oxburgh L, Headon DJ, Sansom OJ, Smits R, Davies JA, Hohenstein P.

Elife. 2015 Feb 3;3:e04000. doi: 10.7554/eLife.04000.


Fucci2a: a bicistronic cell cycle reporter that allows Cre mediated tissue specific expression in mice.

Mort RL, Ford MJ, Sakaue-Sawano A, Lindstrom NO, Casadio A, Douglas AT, Keighren MA, Hohenstein P, Miyawaki A, Jackson IJ.

Cell Cycle. 2014;13(17):2681-96. doi: 10.4161/15384101.2015.945381.


Node retraction during patterning of the urinary collecting duct system.

Lindström NO, Chang CH, Valerius MT, Hohenstein P, Davies JA.

J Anat. 2015 Jan;226(1):13-21. doi: 10.1111/joa.12239. Epub 2014 Oct 8.


Nephrons require Rho-kinase for proximal-distal polarity development.

Lindström NO, Hohenstein P, Davies JA.

Sci Rep. 2013;3:2692. doi: 10.1038/srep02692.


Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis.

Lindström NO, Neves C, McIntosh R, Miedzybrodzka Z, Vargesson N, Collinson JM.

Gene Expr Patterns. 2011 Mar-Apr;11(3-4):221-32. doi: 10.1016/j.gep.2010.12.003. Epub 2010 Dec 16.


Dact2 is expressed in the developing ureteric bud/collecting duct system of the kidney and controls morphogenetic behavior of collecting duct cells.

Lee WC, Hough MT, Liu W, Ekiert R, Lindström NO, Hohenstein P, Davies JA.

Am J Physiol Renal Physiol. 2010 Oct;299(4):F740-51. doi: 10.1152/ajprenal.00148.2010. Epub 2010 Aug 4.

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