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Items: 1 to 50 of 56

1.

PAG1 limits allergen-induced type 2 inflammation in the murine lung.

Ullah MA, Vicente CT, Collinson N, Curren B, Sikder MAA, Sebina I, Simpson J, Varelias A, Lindquist JA, Ferreira MAR, Phipps S.

Allergy. 2019 Jul 18. doi: 10.1111/all.13991. [Epub ahead of print]

PMID:
31321783
2.

Cold shock Y-box binding protein-1 acetylation status in monocytes is associated with systemic inflammation and vascular damage.

Ewert L, Fischer A, Brandt S, Scurt FG, Philipsen L, Müller AJ, Girndt M, Zenclussen AC, Lindquist JA, Gorny X, Mertens PR.

Atherosclerosis. 2018 Nov;278:156-165. doi: 10.1016/j.atherosclerosis.2018.09.020. Epub 2018 Sep 22.

PMID:
30278358
3.

Cold shock proteins: from cellular mechanisms to pathophysiology and disease.

Lindquist JA, Mertens PR.

Cell Commun Signal. 2018 Sep 26;16(1):63. doi: 10.1186/s12964-018-0274-6. Review.

4.

Crosstalk between Akt signaling and cold shock proteins in mediating invasive cell phenotypes.

Hohlfeld R, Brandt S, Bernhardt A, Gorny X, Schindele D, Jandrig B, Schostak M, Isermann B, Lindquist JA, Mertens PR.

Oncotarget. 2018 Apr 10;9(27):19039-19049. doi: 10.18632/oncotarget.24886. eCollection 2018 Apr 10.

5.

Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy.

Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B.

J Am Soc Nephrol. 2017 Nov;28(11):3182-3189. doi: 10.1681/ASN.2016101123. Epub 2017 Jul 10.

6.

Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1.

Bernhardt A, Fehr A, Brandt S, Jerchel S, Ballhause TM, Philipsen L, Stolze S, Geffers R, Weng H, Fischer KD, Isermann B, Brunner-Weinzierl MC, Batra A, Siegmund B, Zhu C, Lindquist JA, Mertens PR.

Kidney Int. 2017 Nov;92(5):1157-1177. doi: 10.1016/j.kint.2017.03.035. Epub 2017 Jun 11.

PMID:
28610763
7.

Regulation of endogenous brakes to kidney fibrosis: turning the view upside down.

Lindquist JA, Schneider A, Mertens PR.

J Mol Med (Berl). 2017 Jun;95(6):571-573. doi: 10.1007/s00109-017-1540-6. No abstract available.

PMID:
28516239
8.

RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts.

Gieseler-Halbach S, Meltendorf S, Pierau M, Weinert S, Heidel FH, Fischer T, Handschuh J, Braun-Dullaeus RC, Schrappe M, Lindquist JA, Mertens PR, Thomas U, Brunner-Weinzierl MC.

Cell Death Differ. 2017 Feb;24(2):371-383. doi: 10.1038/cdd.2016.141. Epub 2016 Dec 23.

9.

Immune complexes and complexity: investigating mechanisms of renal disease.

Lindquist JA, Hildebrandt J, Philipsen L, Mertens PR.

Int Urol Nephrol. 2017 Apr;49(4):735-739. doi: 10.1007/s11255-016-1450-5. Epub 2016 Nov 18.

PMID:
27864659
10.

Early changes in the metabolic profile of activated CD8(+) T cells.

Cammann C, Rath A, Reichl U, Lingel H, Brunner-Weinzierl M, Simeoni L, Schraven B, Lindquist JA.

BMC Cell Biol. 2016 Jul 7;17(1):28. doi: 10.1186/s12860-016-0104-x.

11.

Y-box protein-1/p18 as novel serum marker for ovarian cancer diagnosis: A study by the Tumor Bank Ovarian Cancer (TOC).

Rohr I, Braicu EI, En-Nia A, Heinrich M, Richter R, Chekerov R, Dechend R, Heidecke H, Dragun D, Schäfer R, Gorny X, Lindquist JA, Brandt S, Sehouli J, Mertens PR.

Cytokine. 2016 Sep;85:157-64. doi: 10.1016/j.cyto.2016.06.021. Epub 2016 Jun 29.

PMID:
27371774
12.

Cold Shock Proteins Mediate GN with Mesangioproliferation.

Zhu C, Sauter E, Schreiter A, van Roeyen CR, Ostendorf T, Floege J, Gembardt F, Hugo CP, Isermann B, Lindquist JA, Mertens PR.

J Am Soc Nephrol. 2016 Dec;27(12):3678-3689. Epub 2016 May 5.

13.

Effect of interferon-β1b on CXCR4-dependent chemotaxis in T cells from multiple sclerosis patients.

Wostradowski T, Gudi V, Pul R, Gingele S, Lindquist JA, Stangel M, Lindquist S.

Clin Exp Immunol. 2015 Nov;182(2):162-72. doi: 10.1111/cei.12689. Epub 2015 Aug 31.

14.

Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 Ubiquitination.

Dong W, Wang H, Shahzad K, Bock F, Al-Dabet MM, Ranjan S, Wolter J, Kohli S, Hoffmann J, Dhople VM, Zhu C, Lindquist JA, Esmon CT, Gröne E, Gröne HJ, Madhusudhan T, Mertens PR, Schlüter D, Isermann B.

J Am Soc Nephrol. 2015 Nov;26(11):2789-99. doi: 10.1681/ASN.2014080846. Epub 2015 May 26.

15.

Erratum to: Differential distribution of Y-box-binding protein 1 and cold shock domain protein A in developing and adult human brain.

Bernstein HG, Lindquist JA, Keilhoff G, Dobrowolny H, Brandt S, Steiner J, Bogerts B, Mertens PR.

Brain Struct Funct. 2015 Jul;220(4):2247. doi: 10.1007/s00429-014-0811-z. No abstract available.

PMID:
24938317
16.

Differential distribution of Y-box-binding protein 1 and cold shock domain protein A in developing and adult human brain.

Bernstein HG, Lindquist JA, Keilhoff G, Dobrowolny H, Brandt S, Steiner J, Bogerts B, Mertens PR.

Brain Struct Funct. 2015 Jul;220(4):2235-45. doi: 10.1007/s00429-014-0786-9. Epub 2014 May 11. Erratum in: Brain Struct Funct. 2015 Jul;220(4):2247.

PMID:
24817634
17.

The role of cold shock domain proteins in inflammatory diseases.

Lindquist JA, Brandt S, Bernhardt A, Zhu C, Mertens PR.

J Mol Med (Berl). 2014 Mar;92(3):207-16. doi: 10.1007/s00109-014-1136-3. Epub 2014 Feb 22. Review.

PMID:
24562821
18.

High prevalence of Y-box protein-1/p18 fragment in plasma of patients with malignancies of different origin.

Tacke F, Galm O, Kanig N, Yagmur E, Brandt S, Lindquist JA, Eberhardt CS, Raffetseder U, Mertens PR.

BMC Cancer. 2014 Jan 20;14:33. doi: 10.1186/1471-2407-14-33.

19.

Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities.

van Roeyen CR, Scurt FG, Brandt S, Kuhl VA, Martinkus S, Djudjaj S, Raffetseder U, Royer HD, Stefanidis I, Dunn SE, Dooley S, Weng H, Fischer T, Lindquist JA, Mertens PR.

Cell Commun Signal. 2013 Aug 27;11:63. doi: 10.1186/1478-811X-11-63.

20.

Myofibroblasts, regeneration or renal fibrosis--is there a decisive hint?

Lindquist JA, Mertens PR.

Nephrol Dial Transplant. 2013 Nov;28(11):2678-81. doi: 10.1093/ndt/gft247. Epub 2013 Aug 23.

PMID:
23975753
21.

PAG/Cbp suppression reveals a contribution of CTLA-4 to setting the activation threshold in T cells.

Smida M, Cammann C, Gurbiel S, Kerstin N, Lingel H, Lindquist S, Simeoni L, Brunner-Weinzierl MC, Suchanek M, Schraven B, Lindquist JA.

Cell Commun Signal. 2013 Apr 19;11(1):28. doi: 10.1186/1478-811X-11-28.

22.

T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.

Stirnweiss A, Hartig R, Gieseler S, Lindquist JA, Reichardt P, Philipsen L, Simeoni L, Poltorak M, Merten C, Zuschratter W, Prokazov Y, Paster W, Stockinger H, Harder T, Gunzer M, Schraven B.

Sci Signal. 2013 Feb 19;6(263):ra13. doi: 10.1126/scisignal.2003607.

PMID:
23423439
23.

TCR activation kinetics and feedback regulation in primary human T cells.

Poltorak M, Arndt B, Kowtharapu BS, Reddycherla AV, Witte V, Lindquist JA, Schraven B, Simeoni L.

Cell Commun Signal. 2013 Jan 14;11:4. doi: 10.1186/1478-811X-11-4.

24.

Discrete, qualitative models of interaction networks.

Ballerstein K, Haus UU, Lindquist JA, Beyer T, Schraven B, Weismantel R.

Front Biosci (Schol Ed). 2013 Jan 1;5:149-66. Review.

PMID:
23277042
25.

Analysis of TCR activation kinetics in primary human T cells upon focal or soluble stimulation.

Arndt B, Poltorak M, Kowtharapu BS, Reichardt P, Philipsen L, Lindquist JA, Schraven B, Simeoni L.

J Immunol Methods. 2013 Jan 31;387(1-2):276-83. doi: 10.1016/j.jim.2012.11.006. Epub 2012 Nov 22.

PMID:
23178863
26.

Meeting report: Signal transduction meets systems biology.

Louis-Dit-Sully C, Kubatzky KF, Lindquist JA, Blattner C, Janssen O, Schamel WW.

Cell Commun Signal. 2012 Apr 30;10(1):11. doi: 10.1186/1478-811X-10-11.

27.

Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation.

Lindquist S, Karitkina D, Langnaese K, Posevitz-Fejfar A, Schraven B, Xavier R, Seed B, Lindquist JA.

PLoS One. 2011;6(9):e23978. doi: 10.1371/journal.pone.0023978. Epub 2011 Sep 6.

28.

Integrating signals from the T-cell receptor and the interleukin-2 receptor.

Beyer T, Busse M, Hristov K, Gurbiel S, Smida M, Haus UU, Ballerstein K, Pfeuffer F, Weismantel R, Schraven B, Lindquist JA.

PLoS Comput Biol. 2011 Aug;7(8):e1002121. doi: 10.1371/journal.pcbi.1002121. Epub 2011 Aug 4.

29.

The balance of pro-inflammatory and trophic factors in multiple sclerosis patients: effects of acute relapse and immunomodulatory treatment.

Lindquist S, Hassinger S, Lindquist JA, Sailer M.

Mult Scler. 2011 Jul;17(7):851-66. doi: 10.1177/1352458511399797. Epub 2011 May 11.

PMID:
21561957
30.

Mechanisms of opioid-mediated inhibition of human T cell receptor signaling.

Börner C, Warnick B, Smida M, Hartig R, Lindquist JA, Schraven B, Höllt V, Kraus J.

J Immunol. 2009 Jul 15;183(2):882-9. doi: 10.4049/jimmunol.0802763. Epub 2009 Jun 26.

31.

CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling.

Strauss G, Lindquist JA, Arhel N, Felder E, Karl S, Haas TL, Fulda S, Walczak H, Kirchhoff F, Debatin KM.

J Exp Med. 2009 Jun 8;206(6):1379-93. doi: 10.1084/jem.20082363. Epub 2009 Jun 1.

32.

Signal transduction--receptors, mediators, and genes.

Entschladen F, Lindquist JA, Serfling E, Thiel G, Kieser A, Giehl K, Ehrhardt C, Feller SM, Ullrich O, Schaper F, Janssen O, Hass R, Friedrich K.

Sci Signal. 2009 Mar 24;2(63):mr3. doi: 10.1126/scisignal.263mr3. Review.

PMID:
19318619
33.

Signal transduction in the footsteps of goethe and schiller.

Friedrich K, Lindquist JA, Entschladen F, Serfling E, Thiel G, Kieser A, Giehl K, Ehrhardt C, Feller SM, Ullrich O, Schaper F, Janssen O, Hass R.

Cell Commun Signal. 2009 Feb 4;7:2. doi: 10.1186/1478-811X-7-2.

34.

Control of lymphocyte development and activation by negative regulatory transmembrane adapter proteins.

Simeoni L, Lindquist JA, Smida M, Witte V, Arndt B, Schraven B.

Immunol Rev. 2008 Aug;224:215-28. doi: 10.1111/j.1600-065X.2008.00656.x. Review.

PMID:
18759929
35.

Systems biology of T cell activation.

Lindquist JA, Schraven B.

Ernst Schering Found Symp Proc. 2007;(3):43-61.

PMID:
18510098
36.

Dynamics of proximal signaling events after TCR/CD8-mediated induction of proliferation or apoptosis in mature CD8+ T cells.

Wang X, Simeoni L, Lindquist JA, Saez-Rodriguez J, Ambach A, Gilles ED, Kliche S, Schraven B.

J Immunol. 2008 May 15;180(10):6703-12.

37.

A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration.

Posevitz-Fejfár A, Smída M, Kliche S, Hartig R, Schraven B, Lindquist JA.

Eur J Immunol. 2008 Jan;38(1):250-9.

38.

Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts.

Tauzin S, Ding H, Khatib K, Ahmad I, Burdevet D, van Echten-Deckert G, Lindquist JA, Schraven B, Din NU, Borisch B, Hoessli DC.

Blood. 2008 Feb 15;111(4):2310-20. Epub 2007 Dec 10.

39.

Fyn regulates the duration of TCR engagement needed for commitment to effector function.

Filby A, Seddon B, Kleczkowska J, Salmond R, Tomlinson P, Smida M, Lindquist JA, Schraven B, Zamoyska R.

J Immunol. 2007 Oct 1;179(7):4635-44.

40.

A logical model provides insights into T cell receptor signaling.

Saez-Rodriguez J, Simeoni L, Lindquist JA, Hemenway R, Bommhardt U, Arndt B, Haus UU, Weismantel R, Gilles ED, Klamt S, Schraven B.

PLoS Comput Biol. 2007 Aug;3(8):e163. Epub 2007 Jul 5.

41.

A novel negative regulatory function of the phosphoprotein associated with glycosphingolipid-enriched microdomains: blocking Ras activation.

Smida M, Posevitz-Fejfar A, Horejsi V, Schraven B, Lindquist JA.

Blood. 2007 Jul 15;110(2):596-615. Epub 2007 Mar 27.

42.

Normal T-cell development and immune functions in TRIM-deficient mice.

Kölsch U, Arndt B, Reinhold D, Lindquist JA, Jüling N, Kliche S, Pfeffer K, Bruyns E, Schraven B, Simeoni L.

Mol Cell Biol. 2006 May;26(9):3639-48.

43.

A methodology for the structural and functional analysis of signaling and regulatory networks.

Klamt S, Saez-Rodriguez J, Lindquist JA, Simeoni L, Gilles ED.

BMC Bioinformatics. 2006 Feb 7;7:56.

44.

Right time, right place: the organization of membrane proximal signaling.

Simeoni L, Smida M, Posevitz V, Schraven B, Lindquist JA.

Semin Immunol. 2005 Feb;17(1):35-49. Review.

PMID:
15582487
45.

Transmembrane adapters: structure, biochemistry and biology.

Kliche S, Lindquist JA, Schraven B.

Semin Immunol. 2004 Dec;16(6):367-77. Review.

PMID:
15541652
46.

Decreased iNOS synthesis mediates dexamethasone-induced protection of neurons from inflammatory injury in vitro.

Golde S, Coles A, Lindquist JA, Compston A.

Eur J Neurosci. 2003 Nov;18(9):2527-37.

PMID:
14622153
47.

Transmembrane adapters: attractants for cytoplasmic effectors.

Lindquist JA, Simeoni L, Schraven B.

Immunol Rev. 2003 Feb;191:165-82. Review.

PMID:
12614359
48.

A human TAPBP (TAPASIN)-related gene, TAPBP-R.

Teng MS, Stephens R, Du Pasquier L, Freeman T, Lindquist JA, Trowsdale J.

Eur J Immunol. 2002 Apr;32(4):1059-68.

49.

ER60/ERp57 forms disulfide-bonded intermediates with MHC class I heavy chain.

Lindquist JA, Hämmerling GJ, Trowsdale J.

FASEB J. 2001 Jun;15(8):1448-50. No abstract available.

PMID:
11387253
50.

DAP12 and KAP10 (DAP10)-novel transmembrane adapter proteins of the CD3zeta family.

Wilson MJ, Lindquist JA, Trowsdale J.

Immunol Res. 2000;22(1):21-42. Review.

PMID:
10945225

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