Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 112

1.

Simultaneous measurement of thrombin generation and fibrin formation in whole blood under flow conditions.

Kelchtermans H, Pelkmans L, Bouwhuis A, Schurgers E, Lindhout T, Huskens D, Miszta A, Hemker HC, Lancé MD, de Laat B.

Thromb Haemost. 2016 Jul 4;116(1):134-45. doi: 10.1160/TH15-10-0801. Epub 2016 Apr 14.

PMID:
27074907
2.

Thrombin Generation in Zebrafish Blood.

Schurgers E, Moorlag M, Hemker C, Lindhout T, Kelchtermans H, de Laat B.

PLoS One. 2016 Feb 12;11(2):e0149135. doi: 10.1371/journal.pone.0149135. eCollection 2016.

3.

Effect of five therapeutic strategies on the coagulation defect induced by the thrombomodulin c.1611C>A mutation.

Dargaud Y, Jourdy Y, Le Quellec S, Hemker CH, Lindhout T, Castoldi E, Negrier C.

Br J Haematol. 2016 Sep;174(6):993-6. doi: 10.1111/bjh.13833. Epub 2015 Oct 30. No abstract available.

PMID:
26517807
4.

Hypoxia Induces a Prothrombotic State Independently of the Physical Activity.

Ninivaggi M, de Laat M, Lancé MM, Kicken CH, Pelkmans L, Bloemen S, Dirks ML, van Loon LJ, Govers-Riemslag JW, Lindhout T, Konings J, de Laat B.

PLoS One. 2015 Oct 30;10(10):e0141797. doi: 10.1371/journal.pone.0141797. eCollection 2015.

5.

Characterization of an autosomal dominant bleeding disorder caused by a thrombomodulin mutation.

Dargaud Y, Scoazec JY, Wielders SJ, Trzeciak C, Hackeng TM, Négrier C, Hemker HC, Lindhout T, Castoldi E.

Blood. 2015 Feb 26;125(9):1497-501. doi: 10.1182/blood-2014-10-604553. Epub 2015 Jan 6.

6.

Thrombin-dependent Incorporation of von Willebrand Factor into a Fibrin Network.

Miszta A, Pelkmans L, Lindhout T, Krishnamoorthy G, de Groot PG, Hemker CH, Heemskerk JW, Kelchtermans H, de Laat B.

J Biol Chem. 2014 Dec 26;289(52):35979-86. doi: 10.1074/jbc.M114.591677. Epub 2014 Nov 7.

7.

Whole blood thrombin generation in Bmal1-deficient mice.

Ninivaggi M, Kelchtermans H, Kuijpers MJ, Hemmeryckx B, Heemskerk JW, Lindhout T, Hoylaerts MF, de Laat B.

Thromb Haemost. 2014 Aug;112(2):271-5. doi: 10.1160/TH13-11-0910. Epub 2014 Apr 17.

PMID:
24740693
8.

Biochemical characterization of a polysialyltransferase from Mannheimia haemolytica A2 and comparison to other bacterial polysialyltransferases.

Lindhout T, Bainbridge CR, Costain WJ, Gilbert M, Wakarchuk WW.

PLoS One. 2013 Jul 26;8(7):e69888. doi: 10.1371/journal.pone.0069888. Print 2013.

9.

Conformation of beta2glycoprotein I and its effect on coagulation.

Ninivaggi M, Kelchtermans H, Lindhout T, de Laat B.

Thromb Res. 2012 Oct;130 Suppl 1:S33-6. doi: 10.1016/j.thromres.2012.08.269. Epub 2012 Aug 24. Review.

10.

Enzymatic engineering of polysialic acid on cells in vitro and in vivo using a purified bacterial polysialyltransferase.

El Maarouf A, Moyo-Lee Yaw D, Lindhout T, Pearse DD, Wakarchuk W, Rutishauser U.

J Biol Chem. 2012 Sep 21;287(39):32770-9. Epub 2012 Jul 31.

11.

Whole-blood thrombin generation monitored with a calibrated automated thrombogram-based assay.

Ninivaggi M, Apitz-Castro R, Dargaud Y, de Laat B, Hemker HC, Lindhout T.

Clin Chem. 2012 Aug;58(8):1252-9. doi: 10.1373/clinchem.2012.184077. Epub 2012 Jun 4.

12.

Thrombin generation assay using factor IXa as a trigger to quantify accurately factor VIII levels in haemophilia A.

Ninivaggi M, Dargaud Y, van Oerle R, de Laat B, Hemker HC, Lindhout T.

J Thromb Haemost. 2011 Aug;9(8):1549-55. doi: 10.1111/j.1538-7836.2011.04358.x.

13.

Site-specific enzymatic polysialylation of therapeutic proteins using bacterial enzymes.

Lindhout T, Iqbal U, Willis LM, Reid AN, Li J, Liu X, Moreno M, Wakarchuk WW.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7397-402. doi: 10.1073/pnas.1019266108. Epub 2011 Apr 18.

14.

Differential lipopolysaccharide core capping leads to quantitative and correlated modifications of mechanical and structural properties in Pseudomonas aeruginosa biofilms.

Lau PC, Lindhout T, Beveridge TJ, Dutcher JR, Lam JS.

J Bacteriol. 2009 Nov;191(21):6618-31. doi: 10.1128/JB.00698-09. Epub 2009 Aug 28.

15.

Truncation in the core oligosaccharide of lipopolysaccharide affects flagella-mediated motility in Pseudomonas aeruginosa PAO1 via modulation of cell surface attachment.

Lindhout T, Lau PC, Brewer D, Lam JS.

Microbiology. 2009 Oct;155(Pt 10):3449-60. doi: 10.1099/mic.0.030510-0. Epub 2009 Jul 9.

PMID:
19589832
16.

Absence of platelet-dependent fibrin formation in a patient with Scott syndrome.

Wielders SJ, Broers J, ten Cate H, Collins PW, Bevers EM, Lindhout T.

Thromb Haemost. 2009 Jul;102(1):76-82. doi: 10.1160/TH08-11-0719.

PMID:
19572071
17.

Direct inhibition of phospholipid scrambling activity in erythrocytes by potassium ions.

Wolfs JL, Comfurius P, Bekers O, Zwaal RF, Balasubramanian K, Schroit AJ, Lindhout T, Bevers EM.

Cell Mol Life Sci. 2009 Jan;66(2):314-23. doi: 10.1007/s00018-008-8566-4.

PMID:
18989619
18.

Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase does not inhibit the platelet procoagulant response.

Lindhout T, Wielders S, Hamulyak K, Bevers E, ten Cate H.

J Thromb Haemost. 2008 Aug;6(8):1424-6. doi: 10.1111/j.1538-7836.2008.03023.x. Epub 2008 May 15. No abstract available.

19.

Factor Xa-driven thrombin generation in plasma: dependency on the aminophospholipid density of membranes and inhibition by phospholipid-binding proteins.

Wielders SJ, Ungethüm L, Reutelingsperger CP, Bevers EM, Lindhout T.

Thromb Haemost. 2007 Nov;98(5):1056-62.

PMID:
18000611
20.

Protease-activated receptor-4 inhibition protects from multiorgan failure in a murine model of systemic inflammation.

Slofstra SH, Bijlsma MF, Groot AP, Reitsma PH, Lindhout T, ten Cate H, Spek CA.

Blood. 2007 Nov 1;110(9):3176-82. Epub 2007 Jul 19.

21.

Microparticles adhere to collagen type I, fibrinogen, von Willebrand factor and surface immobilised platelets at physiological shear rates.

Keuren JF, Magdeleyns EJ, Bennaghmouch A, Bevers EM, Curvers J, Lindhout T.

Br J Haematol. 2007 Aug;138(4):527-33. Epub 2007 Jun 29.

PMID:
17608769
22.

Both ADP and thrombin regulate arteriolar thrombus stabilization and embolization, but are not involved in initial hemostasis as induced by micropuncture.

van Gestel MA, Reitsma S, Slaaf DW, Heijnen VV, Feijge MA, Lindhout T, van Zandvoort MA, Elg M, Reneman RS, Heemskerk JW, Egbrink MG.

Microcirculation. 2007 Apr-May;14(3):193-205.

PMID:
17454672
23.

Anticoagulant and antithrombotic properties of intracellular protease-activated receptor antagonists.

Wielders SJ, Bennaghmouch A, Reutelingsperger CP, Bevers EM, Lindhout T.

J Thromb Haemost. 2007 Mar;5(3):571-6. Epub 2006 Dec 13.

24.

Effects of storage-induced platelet microparticles on the initiation and propagation phase of blood coagulation.

Keuren JF, Magdeleyns EJ, Govers-Riemslag JW, Lindhout T, Curvers J.

Br J Haematol. 2006 Aug;134(3):307-13. Erratum in: Br J Haematol. 2006 Nov;135(3):418. Keuren, Jeffery F W [corrected to Keuren, Jeffrey F W].

PMID:
16848773
25.

Rolling and adhesion of apoptotic monocytes is impaired by loss of functional cell surface-expressed P-selectin glycoprotein ligand-1.

van Genderen H, Wielders SJ, Lindhout T, Reutelingsperger CP.

J Thromb Haemost. 2006 Jul;4(7):1611-7.

26.

Factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation.

Daubie V, Cauwenberghs S, Senden NH, Pochet R, Lindhout T, Buurman WA, Heemskerk JW.

Biochim Biophys Acta. 2006 Aug;1763(8):860-9. Epub 2006 May 6.

27.

Reversible inhibition of the platelet procoagulant response through manipulation of the Gardos channel.

Wolfs JL, Wielders SJ, Comfurius P, Lindhout T, Giddings JC, Zwaal RF, Bevers EM.

Blood. 2006 Oct 1;108(7):2223-8. Epub 2006 Jun 1.

28.

Activated scramblase and inhibited aminophospholipid translocase cause phosphatidylserine exposure in a distinct platelet fraction.

Wolfs JL, Comfurius P, Rasmussen JT, Keuren JF, Lindhout T, Zwaal RF, Bevers EM.

Cell Mol Life Sci. 2005 Jul;62(13):1514-25.

PMID:
15971000
29.

Synergistic effect of thrombin on collagen-induced platelet procoagulant activity is mediated through protease-activated receptor-1.

Keuren JF, Wielders SJ, Ulrichts H, Hackeng T, Heemskerk JW, Deckmyn H, Bevers EM, Lindhout T.

Arterioscler Thromb Vasc Biol. 2005 Jul;25(7):1499-505. Epub 2005 Apr 21.

PMID:
15845904
30.

Annexin A5 down-regulates surface expression of tissue factor: a novel mechanism of regulating the membrane receptor repertoir.

Ravassa S, Bennaghmouch A, Kenis H, Lindhout T, Hackeng T, Narula J, Hofstra L, Reutelingsperger C.

J Biol Chem. 2005 Feb 18;280(7):6028-35. Epub 2004 Dec 2.

31.

Facilitating roles of murine platelet glycoprotein Ib and alphaIIbbeta3 in phosphatidylserine exposure during vWF-collagen-induced thrombus formation.

Kuijpers MJ, Schulte V, Oury C, Lindhout T, Broers J, Hoylaerts MF, Nieswandt B, Heemskerk JW.

J Physiol. 2004 Jul 15;558(Pt 2):403-15. Epub 2004 May 21.

32.

Factor XI-dependent reciprocal thrombin generation consolidates blood coagulation when tissue factor is not available.

Wielders SJ, Béguin S, Hemker HC, Lindhout T.

Arterioscler Thromb Vasc Biol. 2004 Jun;24(6):1138-42. Epub 2004 Apr 8.

PMID:
15072993
33.

Coils and tubes releasing heparin. Studies on a new vascular graft prototype.

Aldenhoff YB, Knetsch ML, Hanssen JH, Lindhout T, Wielders SJ, Koole LH.

Biomaterials. 2004 Jul;25(16):3125-33.

PMID:
14980407
34.

Covalently-bound heparin makes collagen thromboresistant.

Keuren JF, Wielders SJ, Driessen A, Verhoeven M, Hendriks M, Lindhout T.

Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):613-7. Epub 2004 Jan 5.

PMID:
14707039
35.

von Willebrand factor C1C2 domain is involved in platelet adhesion to polymerized fibrin at high shear rate.

Keuren JF, Baruch D, Legendre P, Denis CV, Lenting PJ, Girma JP, Lindhout T.

Blood. 2004 Mar 1;103(5):1741-6. Epub 2003 Nov 6.

36.

Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood.

Siljander PR, Munnix IC, Smethurst PA, Deckmyn H, Lindhout T, Ouwehand WH, Farndale RW, Heemskerk JW.

Blood. 2004 Feb 15;103(4):1333-41. Epub 2003 Oct 16.

37.
38.

von Willebrand factor stimulates thrombin-induced exposure of procoagulant phospholipids on the surface of fibrin-adherent platelets.

Briedé JJ, Wielders SJ, Heemskerk JW, Baruch D, Hemker HC, Lindhout T.

J Thromb Haemost. 2003 Mar;1(3):559-65.

39.

Integrin alphaIIbbeta3 and shear-dependent action of glycoprotein Ibalpha stimulate platelet-dependent thrombin formation in stirred plasma.

Keuren JF, Ulrichts H, Feijge MA, Hamulyak K, Deckmyn H, Lindhout T, Heemskerk JW.

J Lab Clin Med. 2003 May;141(5):350-8.

PMID:
12761479
40.

Thrombogenicity of polysaccharide-coated surfaces.

Keuren JF, Wielders SJ, Willems GM, Morra M, Cahalan L, Cahalan P, Lindhout T.

Biomaterials. 2003 May;24(11):1917-24.

PMID:
12615482
41.

Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo.

Kuijpers MJ, Schulte V, Bergmeier W, Lindhout T, Brakebusch C, Offermanns S, Fässler R, Heemskerk JW, Nieswandt B.

FASEB J. 2003 Apr;17(6):685-7. Epub 2003 Feb 5.

PMID:
12586747
42.
43.

Platelet activation and blood coagulation.

Heemskerk JW, Bevers EM, Lindhout T.

Thromb Haemost. 2002 Aug;88(2):186-93. Review.

PMID:
12195687
44.

Fibrinogen adsorption, platelet adhesion and thrombin generation at heparinized surfaces exposed to flowing blood.

Keuren JF, Wielders SJ, Willems GM, Morra M, Lindhout T.

Thromb Haemost. 2002 Apr;87(4):742-7.

PMID:
12008960
45.

Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen.

Nieswandt B, Brakebusch C, Bergmeier W, Schulte V, Bouvard D, Mokhtari-Nejad R, Lindhout T, Heemskerk JW, Zirngibl H, Fässler R.

EMBO J. 2001 May 1;20(9):2120-30.

46.

Contribution of platelet-derived factor Va to thrombin generation on immobilized collagen- and fibrinogen-adherent platelets.

Briedé JJ, Heemskerk JW, van't Veer C, Hemker HC, Lindhout T.

Thromb Haemost. 2001 Mar;85(3):509-13.

PMID:
11307823
47.

Tissue factor activity in human monocytes is regulated by plasma: implications for the high and low responder phenomenon.

Nijziel M, van Oerle R, van 't Veer C, van Pampus E, Lindhout T, Hamulyák K.

Br J Haematol. 2001 Jan;112(1):98-104.

PMID:
11167790
48.

Regulation of platelet factor Va-dependent thrombin generation by activated protein C at the surface of collagen-adherent platelets.

Briedé JJ, Tans G, Willems GM, Hemker HC, Lindhout T.

J Biol Chem. 2001 Mar 9;276(10):7164-8. Epub 2000 Dec 11.

49.

Receptors and signalling mechanisms in the procoagulant response of platelets.

Heemskerk JW, Siljander PR, Bevers EM, Farndale RW, Lindhout T.

Platelets. 2000 Sep;11(6):301-6. Review.

PMID:
11083453
50.

Antibodies to beta2-glycoprotein I associated with antiphospholipid syndrome suppress the inhibitory activity of tissue factor pathway inhibitor.

Salemink I, Blezer R, Willems GM, Galli M, Bevers E, Lindhout T.

Thromb Haemost. 2000 Oct;84(4):653-6.

PMID:
11057865

Supplemental Content

Loading ...
Support Center