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Items: 28

1.

Identification of mycobacterial ribosomal proteins as targets for CD4+ T cells that enhance protective immunity in tuberculosis.

Kennedy SC, Johnson AJ, Bharrhan S, Lindestam Arlehamn CS, Xu J, Garforth SJ, Chan J, Jacobs WR Jr, Sette A, Almo SC, Porcelli SA.

Infect Immun. 2018 Jun 11. pii: IAI.00009-18. doi: 10.1128/IAI.00009-18. [Epub ahead of print]

PMID:
29891545
2.

Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes.

Carrasco Pro S, Lindestam Arlehamn CS, Dhanda SK, Carpenter C, Lindvall M, Faruqi AA, Santee CA, Renz H, Sidney J, Peters B, Sette A.

PLoS One. 2018 May 7;13(5):e0196551. doi: 10.1371/journal.pone.0196551. eCollection 2018.

3.

DAFi: A directed recursive data filtering and clustering approach for improving and interpreting data clustering identification of cell populations from polychromatic flow cytometry data.

Lee AJ, Chang I, Burel JG, Lindestam Arlehamn CS, Mandava A, Weiskopf D, Peters B, Sette A, Scheuermann RH, Qian Y.

Cytometry A. 2018 Jun;93(6):597-610. doi: 10.1002/cyto.a.23371. Epub 2018 Apr 17.

PMID:
29665244
4.

Transcriptomic Analysis of CD4+ T Cells Reveals Novel Immune Signatures of Latent Tuberculosis.

Burel JG, Lindestam Arlehamn CS, Khan N, Seumois G, Greenbaum JA, Taplitz R, Gilman RH, Saito M, Vijayanand P, Sette A, Peters B.

J Immunol. 2018 May 1;200(9):3283-3290. doi: 10.4049/jimmunol.1800118. Epub 2018 Mar 30.

PMID:
29602771
5.

A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection.

Whatney WE, Gandhi NR, Lindestam Arlehamn CS, Nizam A, Wu H, Quezada MJ, Campbell A, Allana S, Kabongo MM, Khayumbi J, Muchiri B, Ongalo J, Tonui J, Sasser LE, Fergus TJ, Ouma GS, Ouma SG, Beck AA, Mulligan MJ, Oladele A, Kaushal D, Cain KP, Waller L, Blumberg HM, Altman JD, Ernst JD, Rengarajan J, Day CL; TBRU-ASTRa Study Group.

J Immunol. 2018 Apr 15;200(8):3008-3019. doi: 10.4049/jimmunol.1701737. Epub 2018 Mar 14.

PMID:
29540577
6.

Correction: Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses.

da Silva Antunes R, Paul S, Sidney J, Weiskopf D, Dan JM, Phillips E, Mallal S, Crotty S, Sette A, Lindestam Arlehamn CS.

PLoS One. 2018 Feb 20;13(2):e0193382. doi: 10.1371/journal.pone.0193382. eCollection 2018.

7.

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 159 individuals from the Worcester region of the Western Cape province of South Africa.

Grifoni A, Sidney J, Carpenter C, Phillips E, Mallal S, Scriba TJ, Sette A, Lindestam Arlehamn CS.

Hum Immunol. 2018 Mar;79(3):143-144. doi: 10.1016/j.humimm.2018.01.004.

PMID:
29398200
8.

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 714 adults from Colombo, Sri Lanka.

Grifoni A, Weiskopf D, Lindestam Arlehamn CS, Angelo M, Leary S, Sidney J, Frazier A, Phillips E, Mallal S, Mack SJ, Tippalagama R, Goonewardana S, Premawansa S, Premawansa G, Wijewickrama A, De Silva AD, Sette A.

Hum Immunol. 2018 Feb;79(2):87-88. doi: 10.1016/j.humimm.2017.12.007. Epub 2017 Dec 28.

PMID:
29289740
9.

Large-Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata.

Lindestam Arlehamn CS, Paul S, Chun Wang EH, de Jong A, Christiano AM, Sette A.

J Investig Dermatol Symp Proc. 2018 Jan;19(1):S54-S56. doi: 10.1016/j.jisp.2017.10.001. No abstract available.

PMID:
29273108
10.

Large Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata.

Lindestam Arlehamn CS, Paul S, Wang EHC, de Jong A, Christiano AM, Sette A.

J Invest Dermatol. 2017 Aug 29. pii: S0022-202X(17)32832-4. doi: 10.1016/j.jid.2017.08.018. [Epub ahead of print] No abstract available.

PMID:
28864075
11.

T cells from patients with Parkinson's disease recognize α-synuclein peptides.

Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, Dillon MB, Carpenter C, Weiskopf D, Phillips E, Mallal S, Peters B, Frazier A, Lindestam Arlehamn CS, Sette A.

Nature. 2017 Jun 29;546(7660):656-661. doi: 10.1038/nature22815. Epub 2017 Jun 21. Erratum in: Nature. 2017 Sep 13;549(7671):292.

12.

Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis.

Moguche AO, Musvosvi M, Penn-Nicholson A, Plumlee CR, Mearns H, Geldenhuys H, Smit E, Abrahams D, Rozot V, Dintwe O, Hoff ST, Kromann I, Ruhwald M, Bang P, Larson RP, Shafiani S, Ma S, Sherman DR, Sette A, Lindestam Arlehamn CS, McKinney DM, Maecker H, Hanekom WA, Hatherill M, Andersen P, Scriba TJ, Urdahl KB.

Cell Host Microbe. 2017 Jun 14;21(6):695-706.e5. doi: 10.1016/j.chom.2017.05.012.

13.

Identification of Mycobacterial RplJ/L10 and RpsA/S1 Proteins as Novel Targets for CD4+ T Cells.

Johnson AJ, Kennedy SC, Lindestam Arlehamn CS, Goldberg MF, Saini NK, Xu J, Paul S, Hegde SS, Blanchard JS, Chan J, Jacobs WR Jr, Sette A, Porcelli SA.

Infect Immun. 2017 Mar 23;85(4). pii: e01023-16. doi: 10.1128/IAI.01023-16. Print 2017 Apr.

14.

Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses.

da Silva Antunes R, Paul S, Sidney J, Weiskopf D, Dan JM, Phillips E, Mallal S, Crotty S, Sette A, Lindestam Arlehamn CS.

PLoS One. 2017 Jan 12;12(1):e0169086. doi: 10.1371/journal.pone.0169086. eCollection 2017. Erratum in: PLoS One. 2018 Feb 20;13(2):e0193382.

15.

HIV Interferes with Mycobacterium tuberculosis Antigen Presentation in Human Dendritic Cells.

Singh SK, Andersson AM, Ellegård R, Lindestam Arlehamn CS, Sette A, Larsson M, Stendahl O, Blomgran R.

Am J Pathol. 2016 Dec;186(12):3083-3093. doi: 10.1016/j.ajpath.2016.08.003. Epub 2016 Oct 13.

PMID:
27746182
16.

A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans.

Lindestam Arlehamn CS, McKinney DM, Carpenter C, Paul S, Rozot V, Makgotlho E, Gregg Y, van Rooyen M, Ernst JD, Hatherill M, Hanekom WA, Peters B, Scriba TJ, Sette A.

PLoS Pathog. 2016 Jul 13;12(7):e1005760. doi: 10.1371/journal.ppat.1005760. eCollection 2016 Jul.

17.

A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.

Dan JM, Lindestam Arlehamn CS, Weiskopf D, da Silva Antunes R, Havenar-Daughton C, Reiss SM, Brigger M, Bothwell M, Sette A, Crotty S.

J Immunol. 2016 Aug 1;197(3):983-93. doi: 10.4049/jimmunol.1600318. Epub 2016 Jun 24.

18.

Th1 versus Th2 T cell polarization by whole-cell and acellular childhood pertussis vaccines persists upon re-immunization in adolescence and adulthood.

Bancroft T, Dillon MB, da Silva Antunes R, Paul S, Peters B, Crotty S, Lindestam Arlehamn CS, Sette A.

Cell Immunol. 2016 Jun-Jul;304-305:35-43. doi: 10.1016/j.cellimm.2016.05.002. Epub 2016 May 14.

19.

The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans.

Mothé BR, Lindestam Arlehamn CS, Dow C, Dillon MBC, Wiseman RW, Bohn P, Karl J, Golden NA, Gilpin T, Foreman TW, Rodgers MA, Mehra S, Scriba TJ, Flynn JL, Kaushal D, O'Connor DH, Sette A.

Tuberculosis (Edinb). 2015 Dec;95(6):722-735. doi: 10.1016/j.tube.2015.07.005. Epub 2015 Aug 28.

20.

A side-by-side comparison of T cell reactivity to fifty-nine Mycobacterium tuberculosis antigens in diverse populations from five continents.

Carpenter C, Sidney J, Kolla R, Nayak K, Tomiyama H, Tomiyama C, Padilla OA, Rozot V, Ahamed SF, Ponte C, Rolla V, Antas PR, Chandele A, Kenneth J, Laxmi S, Makgotlho E, Vanini V, Ippolito G, Kazanova AS, Panteleev AV, Hanekom W, Mayanja-Kizza H, Lewinsohn D, Saito M, McElrath MJ, Boom WH, Goletti D, Gilman R, Lyadova IV, Scriba TJ, Kallas EG, Murali-Krishna K, Sette A, Lindestam Arlehamn CS.

Tuberculosis (Edinb). 2015 Dec;95(6):713-721. doi: 10.1016/j.tube.2015.07.001. Epub 2015 Aug 1.

21.

An open-source computational and data resource to analyze digital maps of immunopeptidomes.

Caron E, Espona L, Kowalewski DJ, Schuster H, Ternette N, Alpízar A, Schittenhelm RB, Ramarathinam SH, Lindestam Arlehamn CS, Chiek Koh C, Gillet LC, Rabsteyn A, Navarro P, Kim S, Lam H, Sturm T, Marcilla M, Sette A, Campbell DS, Deutsch EW, Moritz RL, Purcell AW, Rammensee HG, Stevanovic S, Aebersold R.

Elife. 2015 Jul 8;4. doi: 10.7554/eLife.07661.

22.

Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes.

Paul S, Lindestam Arlehamn CS, Scriba TJ, Dillon MB, Oseroff C, Hinz D, McKinney DM, Carrasco Pro S, Sidney J, Peters B, Sette A.

J Immunol Methods. 2015 Jul;422:28-34. doi: 10.1016/j.jim.2015.03.022. Epub 2015 Apr 7.

23.

Immunological consequences of intragenus conservation of Mycobacterium tuberculosis T-cell epitopes.

Lindestam Arlehamn CS, Paul S, Mele F, Huang C, Greenbaum JA, Vita R, Sidney J, Peters B, Sallusto F, Sette A.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):E147-55. doi: 10.1073/pnas.1416537112. Epub 2014 Dec 29.

24.

Antigens for CD4 and CD8 T cells in tuberculosis.

Lindestam Arlehamn CS, Lewinsohn D, Sette A, Lewinsohn D.

Cold Spring Harb Perspect Med. 2014 May 22;4(7):a018465. doi: 10.1101/cshperspect.a018465. Review.

25.

Definition of CD4 Immunosignatures Associated with MTB.

Lindestam Arlehamn CS, Sette A.

Front Immunol. 2014 Mar 24;5:124. doi: 10.3389/fimmu.2014.00124. eCollection 2014. Review.

26.

Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.

Schulten V, Greenbaum JA, Hauser M, McKinney DM, Sidney J, Kolla R, Lindestam Arlehamn CS, Oseroff C, Alam R, Broide DH, Ferreira F, Grey HM, Sette A, Peters B.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3459-64. doi: 10.1073/pnas.1300512110. Epub 2013 Feb 11. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5269. Ferreira-Briza, Fatima [corrected to Ferreira, Fatima]. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8750.

27.

Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.

Lindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A.

PLoS Pathog. 2013 Jan;9(1):e1003130. doi: 10.1371/journal.ppat.1003130. Epub 2013 Jan 24.

28.

Expression and regulation of the Escherichia coli O157:H7 effector proteins NleH1 and NleH2.

Holmes A, Lindestam Arlehamn CS, Wang D, Mitchell TJ, Evans TJ, Roe AJ.

PLoS One. 2012;7(3):e33408. doi: 10.1371/journal.pone.0033408. Epub 2012 Mar 12.

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