Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 83

1.

Monitoring RhoGDI Extraction of Lipid-Modified Rho GTPases from Membranes Using Click Chemistry.

Nishimura A, Linder ME.

Methods Mol Biol. 2019;2009:297-306. doi: 10.1007/978-1-4939-9532-5_22.

PMID:
31152412
2.

Purification of Recombinant DHHC Proteins Using an Insect Cell Expression System.

Malgapo MIP, Linder ME.

Methods Mol Biol. 2019;2009:179-189. doi: 10.1007/978-1-4939-9532-5_14.

PMID:
31152404
3.

SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a.

Jing H, Zhang X, Wisner SA, Chen X, Spiegelman NA, Linder ME, Lin H.

Elife. 2017 Dec 14;6. pii: e32436. doi: 10.7554/eLife.32436.

4.

Structure and function of DHHC protein S-acyltransferases.

Gottlieb CD, Linder ME.

Biochem Soc Trans. 2017 Aug 15;45(4):923-8. doi: 10.1042/BST20160304. Epub 2017 Jun 19. Review.

PMID:
28630137
5.

The Cysteine-rich Domain of the DHHC3 Palmitoyltransferase Is Palmitoylated and Contains Tightly Bound Zinc.

Gottlieb CD, Zhang S, Linder ME.

J Biol Chem. 2015 Dec 4;290(49):29259-69. doi: 10.1074/jbc.M115.691147. Epub 2015 Oct 20.

6.

Protein S-palmitoylation and cancer.

Yeste-Velasco M, Linder ME, Lu YJ.

Biochim Biophys Acta. 2015 Aug;1856(1):107-20. doi: 10.1016/j.bbcan.2015.06.004. Epub 2015 Jun 22.

PMID:
26112306
7.

Total synthesis of a functional designer eukaryotic chromosome.

Annaluru N, Muller H, Mitchell LA, Ramalingam S, Stracquadanio G, Richardson SM, Dymond JS, Kuang Z, Scheifele LZ, Cooper EM, Cai Y, Zeller K, Agmon N, Han JS, Hadjithomas M, Tullman J, Caravelli K, Cirelli K, Guo Z, London V, Yeluru A, Murugan S, Kandavelou K, Agier N, Fischer G, Yang K, Martin JA, Bilgel M, Bohutski P, Boulier KM, Capaldo BJ, Chang J, Charoen K, Choi WJ, Deng P, DiCarlo JE, Doong J, Dunn J, Feinberg JI, Fernandez C, Floria CE, Gladowski D, Hadidi P, Ishizuka I, Jabbari J, Lau CY, Lee PA, Li S, Lin D, Linder ME, Ling J, Liu J, Liu J, London M, Ma H, Mao J, McDade JE, McMillan A, Moore AM, Oh WC, Ouyang Y, Patel R, Paul M, Paulsen LC, Qiu J, Rhee A, Rubashkin MG, Soh IY, Sotuyo NE, Srinivas V, Suarez A, Wong A, Wong R, Xie WR, Xu Y, Yu AT, Koszul R, Bader JS, Boeke JD, Chandrasegaran S.

Science. 2014 Apr 4;344(6179):55-8. doi: 10.1126/science.1249252. Epub 2014 Mar 27. Erratum in: Science. 2014 May 23;344(6186):816.

8.

Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts.

Hilgemann DW, Fine M, Linder ME, Jennings BC, Lin MJ.

Elife. 2013 Nov 26;2:e01293. doi: 10.7554/eLife.01293.

9.

Oligomerization of DHHC protein S-acyltransferases.

Lai J, Linder ME.

J Biol Chem. 2013 Aug 2;288(31):22862-70. doi: 10.1074/jbc.M113.458794. Epub 2013 Jun 22.

10.

Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding.

Nishimura A, Linder ME.

Mol Cell Biol. 2013 Apr;33(7):1417-29. doi: 10.1128/MCB.01398-12. Epub 2013 Jan 28.

11.

Mechanism and function of DHHC S-acyltransferases.

Linder ME, Jennings BC.

Biochem Soc Trans. 2013 Feb 1;41(1):29-34. doi: 10.1042/BST20120328.

PMID:
23356254
12.

DHHC protein S-acyltransferases use similar ping-pong kinetic mechanisms but display different acyl-CoA specificities.

Jennings BC, Linder ME.

J Biol Chem. 2012 Mar 2;287(10):7236-45. doi: 10.1074/jbc.M111.337246. Epub 2012 Jan 13.

13.

Exploring protein lipidation with chemical biology.

Hang HC, Linder ME.

Chem Rev. 2011 Oct 12;111(10):6341-58. doi: 10.1021/cr2001977. Epub 2011 Sep 16. Review. No abstract available.

14.

Plasma membrane association of p63 Rho guanine nucleotide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cells.

Aittaleb M, Nishimura A, Linder ME, Tesmer JJ.

J Biol Chem. 2011 Sep 30;286(39):34448-56. doi: 10.1074/jbc.M111.273342. Epub 2011 Aug 10.

15.

Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein.

Jia L, Linder ME, Blumer KJ.

J Biol Chem. 2011 Apr 15;286(15):13695-703. doi: 10.1074/jbc.M110.193763. Epub 2011 Feb 22.

16.

FKBP12 binds to acylated H-ras and promotes depalmitoylation.

Ahearn IM, Tsai FD, Court H, Zhou M, Jennings BC, Ahmed M, Fehrenbacher N, Linder ME, Philips MR.

Mol Cell. 2011 Jan 21;41(2):173-85. doi: 10.1016/j.molcel.2011.01.001.

17.

Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity.

Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E.

Sci Signal. 2010 May 11;3(121):ra37. doi: 10.1126/scisignal.2000647.

18.

Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3.

Nadolski MJ, Linder ME.

J Biol Chem. 2009 Jun 26;284(26):17720-30. doi: 10.1074/jbc.M109.005447. Epub 2009 May 5.

19.

Neuroscience: greasy proteins of the neuron.

Linder ME.

Nature. 2008 Dec 18;456(7224):887-8. doi: 10.1038/456887a. No abstract available.

PMID:
19092922
20.

Differential palmitoylation of the endosomal SNAREs syntaxin 7 and syntaxin 8.

He Y, Linder ME.

J Lipid Res. 2009 Mar;50(3):398-404. doi: 10.1194/jlr.M800360-JLR200. Epub 2008 Oct 31.

21.

2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro.

Jennings BC, Nadolski MJ, Ling Y, Baker MB, Harrison ML, Deschenes RJ, Linder ME.

J Lipid Res. 2009 Feb;50(2):233-42. doi: 10.1194/jlr.M800270-JLR200. Epub 2008 Sep 30.

22.

Protein lipidation.

Nadolski MJ, Linder ME.

FEBS J. 2007 Oct;274(20):5202-10. Epub 2007 Sep 24. Review.

23.

Palmitoylation: policing protein stability and traffic.

Linder ME, Deschenes RJ.

Nat Rev Mol Cell Biol. 2007 Jan;8(1):74-84. Review.

PMID:
17183362
24.

Purification and characterization of recombinant protein acyltransferases.

Budde C, Schoenfish MJ, Linder ME, Deschenes RJ.

Methods. 2006 Oct;40(2):143-50. Review.

25.

R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism.

Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ.

J Biol Chem. 2006 Sep 22;281(38):28222-31. Epub 2006 Jul 25.

26.

Protein palmitoylation by a family of DHHC protein S-acyltransferases.

Mitchell DA, Vasudevan A, Linder ME, Deschenes RJ.

J Lipid Res. 2006 Jun;47(6):1118-27. Epub 2006 Apr 1. Review.

28.

The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p.

Smotrys JE, Schoenfish MJ, Stutz MA, Linder ME.

J Cell Biol. 2005 Sep 26;170(7):1091-9.

29.

DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras.

Swarthout JT, Lobo S, Farh L, Croke MR, Greentree WK, Deschenes RJ, Linder ME.

J Biol Chem. 2005 Sep 2;280(35):31141-8. Epub 2005 Jul 6.

30.

Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.

Drenan RM, Doupnik CA, Boyle MP, Muglia LJ, Huettner JE, Linder ME, Blumer KJ.

J Cell Biol. 2005 May 23;169(4):623-33. Epub 2005 May 16.

31.

The RGS14 GoLoco domain discriminates among Galphai isoforms.

Mittal V, Linder ME.

J Biol Chem. 2004 Nov 5;279(45):46772-8. Epub 2004 Aug 26.

32.

Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family.

Embry AC, Glick JL, Linder ME, Casey PJ.

Mol Pharmacol. 2004 Nov;66(5):1325-31. Epub 2004 Aug 12.

PMID:
15308761
33.

Palmitoylation of intracellular signaling proteins: regulation and function.

Smotrys JE, Linder ME.

Annu Rev Biochem. 2004;73:559-87. Review.

PMID:
15189153
34.

Model organisms lead the way to protein palmitoyltransferases.

Linder ME, Deschenes RJ.

J Cell Sci. 2004 Feb 1;117(Pt 4):521-6.

35.

Analysis of RGS protein palmitoylation.

Bernstein LS, Linder ME, Hepler JR.

Methods Mol Biol. 2004;237:195-204. Review.

PMID:
14501051
36.

Purification of recombinant G protein alpha subunits from Escherichia coli.

Greentree WK, Linder ME.

Methods Mol Biol. 2004;237:3-20. Review.

PMID:
14501035
37.

New insights into the mechanisms of protein palmitoylation.

Linder ME, Deschenes RJ.

Biochemistry. 2003 Apr 22;42(15):4311-20. Review.

PMID:
12693927
38.

Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.

Lobo S, Greentree WK, Linder ME, Deschenes RJ.

J Biol Chem. 2002 Oct 25;277(43):41268-73. Epub 2002 Aug 21.

39.

Distinct sites on G protein beta gamma subunits regulate different effector functions.

Mirshahi T, Mittal V, Zhang H, Linder ME, Logothetis DE.

J Biol Chem. 2002 Sep 27;277(39):36345-50. Epub 2002 Jul 17.

40.

SNAP-25 traffics to the plasma membrane by a syntaxin-independent mechanism.

Loranger SS, Linder ME.

J Biol Chem. 2002 Sep 13;277(37):34303-9. Epub 2002 Jul 11.

41.
42.

Role of the gamma subunit prenyl moiety in G protein beta gamma complex interaction with phospholipase Cbeta.

Fogg VC, Azpiazu I, Linder ME, Smrcka A, Scarlata S, Gautam N.

J Biol Chem. 2001 Nov 9;276(45):41797-802. Epub 2001 Sep 6.

43.

SCH-202676: An allosteric modulator of both agonist and antagonist binding to G protein-coupled receptors.

Fawzi AB, Macdonald D, Benbow LL, Smith-Torhan A, Zhang H, Weig BC, Ho G, Tulshian D, Linder ME, Graziano MP.

Mol Pharmacol. 2001 Jan;59(1):30-7.

PMID:
11125021
44.

Differential effects of acyl-CoA binding protein on enzymatic and non-enzymatic thioacylation of protein and peptide substrates.

Dunphy JT, Schroeder H, Leventis R, Greentree WK, Knudsen JK, Silvius JR, Linder ME.

Biochim Biophys Acta. 2000 May 31;1485(2-3):185-98.

PMID:
10832099
45.

RGS4 binds to membranes through an amphipathic alpha -helix.

Bernstein LS, Grillo AA, Loranger SS, Linder ME.

J Biol Chem. 2000 Jun 16;275(24):18520-6.

47.

Lipid-dependent targeting of G proteins into rafts.

Moffett S, Brown DA, Linder ME.

J Biol Chem. 2000 Jan 21;275(3):2191-8.

48.

G protein selectivity is a determinant of RGS2 function.

Heximer SP, Srinivasa SP, Bernstein LS, Bernard JL, Linder ME, Hepler JR, Blumer KJ.

J Biol Chem. 1999 Nov 26;274(48):34253-9.

49.

SNAP-25 is targeted to the plasma membrane through a novel membrane-binding domain.

Gonzalo S, Greentree WK, Linder ME.

J Biol Chem. 1999 Jul 23;274(30):21313-8.

50.

The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi.

Frazier WA, Gao AG, Dimitry J, Chung J, Brown EJ, Lindberg FP, Linder ME.

J Biol Chem. 1999 Mar 26;274(13):8554-60.

Supplemental Content

Loading ...
Support Center