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Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson's Disease: The Systemic Synuclein Sampling Study (S4).

Chahine LM, Beach TG, Seedorff N, Caspell-Garcia C, Coffey CS, Brumm M, Adler CH, Serrano GE, Linder C, Mosovsky S, Foroud T, Riss H, Ecklund D, Seibyl J, Jennings D, Arnedo V, Riley L, Dave KD, Mollenhauer B; Systemic sSynuclein Sampling study.

J Parkinsons Dis. 2018;8(4):517-527. doi: 10.3233/JPD-181434.


Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4).

Beach TG, Serrano GE, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbillé AG, Letournel F, Munoz DG, White CL 3rd, Schneider J, Crary JF, Sue LI, Adler CH, Glass MJ, Intorcia AJ, Walker JE, Foroud T, Coffey CS, Ecklund D, Riss H, Goßmann J, König F, Kopil CM, Arnedo V, Riley L, Linder C, Dave KD, Jennings D, Seibyl J, Mollenhauer B, Chahine L; Systemic Synuclein Sampling Study (S4) .

J Neuropathol Exp Neurol. 2018 Sep 1;77(9):793-802. doi: 10.1093/jnen/nly056.


Sarcoma in neurofibromatosis 2: case report and review of the literature.

Linder C, Smith MJ, Bulman M, Wallace A, Freemont AJ, Mangham DC, Evans DGR.

Fam Cancer. 2018 May 14. doi: 10.1007/s10689-018-0084-4. [Epub ahead of print]


Understanding the relationship between cell death and tissue shrinkage via a stochastic agent-based model.

Lejeune E, Linder C.

J Biomech. 2018 May 17;73:9-17. doi: 10.1016/j.jbiomech.2018.03.019. Epub 2018 Mar 17.


Microstructural origin of resistance-strain hysteresis in carbon nanotube thin film conductors.

Jin L, Chortos A, Lian F, Pop E, Linder C, Bao Z, Cai W.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):1986-1991. doi: 10.1073/pnas.1717217115. Epub 2018 Feb 12.


Modeling mechanical inhomogeneities in small populations of proliferating monolayers and spheroids.

Lejeune E, Linder C.

Biomech Model Mechanobiol. 2018 Jun;17(3):727-743. doi: 10.1007/s10237-017-0989-0. Epub 2017 Dec 2.


Carbamazepine, lamotrigine, levetiracetam and valproic acid in dried blood spots with liquid chromatography tandem mass spectrometry; method development and validation.

Linder C, Hansson A, Sadek S, Gustafsson LL, Pohanka A.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 1;1072:116-122. doi: 10.1016/j.jchromb.2017.11.005. Epub 2017 Nov 4.


High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar.

Spencer SA, Penney JMSJ, Russell HJ, Howe AP, Linder C, Rakotomampianina ALD, Nandimbiniaina AM, Squire SB, Stothard JR, Bustinduy AL, Rahetilahy AM.

Parasit Vectors. 2017 Jun 24;10(1):307. doi: 10.1186/s13071-017-2249-7.


A highly stretchable, transparent, and conductive polymer.

Wang Y, Zhu C, Pfattner R, Yan H, Jin L, Chen S, Molina-Lopez F, Lissel F, Liu J, Rabiah NI, Chen Z, Chung JW, Linder C, Toney MF, Murmann B, Bao Z.

Sci Adv. 2017 Mar 10;3(3):e1602076. doi: 10.1126/sciadv.1602076. eCollection 2017 Mar.


Treatment efficiency and economic feasibility of biological oxidation, membrane filtration and separation processes, and advanced oxidation for the purification and valorization of olive mill wastewater.

Ioannou-Ttofa L, Michael-Kordatou I, Fattas SC, Eusebio A, Ribeiro B, Rusan M, Amer AR, Zuraiqi S, Waismand M, Linder C, Wiesman Z, Gilron J, Fatta-Kassinos D.

Water Res. 2017 May 1;114:1-13. doi: 10.1016/j.watres.2017.02.020. Epub 2017 Feb 12.


Modeling tumor growth with peridynamics.

Lejeune E, Linder C.

Biomech Model Mechanobiol. 2017 Aug;16(4):1141-1157. doi: 10.1007/s10237-017-0876-8. Epub 2017 Jan 26.


Quantifying the relationship between cell division angle and morphogenesis through computational modeling.

Lejeune E, Linder C.

J Theor Biol. 2017 Apr 7;418:1-7. doi: 10.1016/j.jtbi.2017.01.026. Epub 2017 Jan 22.


Highly stretchable polymer semiconductor films through the nanoconfinement effect.

Xu J, Wang S, Wang GN, Zhu C, Luo S, Jin L, Gu X, Chen S, Feig VR, To JW, Rondeau-Gagné S, Park J, Schroeder BC, Lu C, Oh JY, Wang Y, Kim YH, Yan H, Sinclair R, Zhou D, Xue G, Murmann B, Linder C, Cai W, Tok JB, Chung JW, Bao Z.

Science. 2017 Jan 6;355(6320):59-64. doi: 10.1126/science.aah4496.


Comparison between dried blood spot and plasma sampling for therapeutic drug monitoring of antiepileptic drugs in children with epilepsy: A step towards home sampling.

Linder C, Wide K, Walander M, Beck O, Gustafsson LL, Pohanka A.

Clin Biochem. 2017 May;50(7-8):418-424. doi: 10.1016/j.clinbiochem.2016.12.008. Epub 2016 Dec 24.


Case Report: ECT in a Patient With Primary Parkinsonian Syndrome and Schizophrenia.

Baldinger-Melich P, Weidenauer A, Linder C, Hienert M, Kasper S, Stamenkovic M, Willeit M.

J ECT. 2017 Mar;33(1):e2-e3. doi: 10.1097/YCT.0000000000000363. No abstract available.


Tri-layer wrinkling as a mechanism for anchoring center initiation in the developing cerebellum.

Lejeune E, Javili A, Weickenmeier J, Kuhl E, Linder C.

Soft Matter. 2016 Jul 7;12(25):5613-20. doi: 10.1039/c6sm00526h. Epub 2016 Jun 2.


A highly stretchable autonomous self-healing elastomer.

Li CH, Wang C, Keplinger C, Zuo JL, Jin L, Sun Y, Zheng P, Cao Y, Lissel F, Linder C, You XZ, Bao Z.

Nat Chem. 2016 Jun;8(6):618-24. doi: 10.1038/nchem.2492. Epub 2016 Apr 18.


Abnormal involuntary movements are linked to psychosis-risk in children and adolescents: Results of a population-based study.

Kindler J, Schultze-Lutter F, Michel C, Martz-Irngartinger A, Linder C, Schmidt SJ, Stegmayer K, Schimmelmann BG, Walther S.

Schizophr Res. 2016 Jul;174(1-3):58-64. doi: 10.1016/j.schres.2016.04.032. Epub 2016 May 7.


Longitudinal changes in cognition in early Parkinson's disease patients with REM sleep behavior disorder.

Chahine LM, Xie SX, Simuni T, Tran B, Postuma R, Amara A, Oertel WH, Iranzo A, Scordia C, Fullard M, Linder C, Purri R, Darin A, Rennert L, Videnovic A, Del Riva P, Weintraub D.

Parkinsonism Relat Disord. 2016 Jun;27:102-6. doi: 10.1016/j.parkreldis.2016.03.006. Epub 2016 Mar 12.


Olfactory impairment predicts cognitive decline in early Parkinson's disease.

Fullard ME, Tran B, Xie SX, Toledo JB, Scordia C, Linder C, Purri R, Weintraub D, Duda JE, Chahine LM, Morley JF.

Parkinsonism Relat Disord. 2016 Apr;25:45-51. doi: 10.1016/j.parkreldis.2016.02.013. Epub 2016 Feb 19.


Genome-Wide Association Study in Arabidopsis thaliana of Natural Variation in Seed Oil Melting Point: A Widespread Adaptive Trait in Plants.

Branham SE, Wright SJ, Reba A, Morrison GD, Linder CR.

J Hered. 2016 May;107(3):257-65. doi: 10.1093/jhered/esw008. Epub 2016 Feb 10.


Genome-Wide Association Study of Arabidopsis thaliana Identifies Determinants of Natural Variation in Seed Oil Composition.

Branham SE, Wright SJ, Reba A, Linder CR.

J Hered. 2016 May;107(3):248-56. doi: 10.1093/jhered/esv100. Epub 2015 Dec 24.


Understanding geometric instabilities in thin films via a multi-layer model.

Lejeune E, Javili A, Linder C.

Soft Matter. 2016 Jan 21;12(3):806-16. doi: 10.1039/c5sm02082d. Epub 2015 Nov 4.


Correction: Sandbox University: Estimating Influence of Institutional Action.

Forsman J, Mann RP, Linder C, van den Bogaard M.

PLoS One. 2015 Oct 23;10(10):e0141705. doi: 10.1371/journal.pone.0141705. eCollection 2015. No abstract available.


A LC-MS/MS method for therapeutic drug monitoring of carbamazepine, lamotrigine and valproic acid in DBS.

Linder C, Andersson M, Wide K, Beck O, Pohanka A.

Bioanalysis. 2015;7(16):2031-9. doi: 10.4155/bio.15.99.


Liquid-phase characterization of molecular interactions in polyunsaturated and n-fatty acid methyl esters by (1)H low-field nuclear magnetic resonance.

Meiri N, Berman P, Colnago LA, Moraes TB, Linder C, Wiesman Z.

Biotechnol Biofuels. 2015 Jul 7;8:96. doi: 10.1186/s13068-015-0280-5. eCollection 2015.


Bolaamphiphiles as carriers for siRNA delivery: From chemical syntheses to practical applications.

Gupta K, Afonin KA, Viard M, Herrero V, Kasprzak W, Kagiampakis I, Kim T, Koyfman AY, Puri A, Stepler M, Sappe A, KewalRamani VN, Grinberg S, Linder C, Heldman E, Blumenthal R, Shapiro BA.

J Control Release. 2015 Sep 10;213:142-151. doi: 10.1016/j.jconrel.2015.06.041. Epub 2015 Jul 4.


Age matters in the prevalence and clinical significance of ultra-high-risk for psychosis symptoms and criteria in the general population: Findings from the BEAR and BEARS-kid studies.

Schimmelmann BG, Michel C, Martz-Irngartinger A, Linder C, Schultze-Lutter F.

World Psychiatry. 2015 Jun;14(2):189-97. doi: 10.1002/wps.20216.


Study of liquid-phase molecular packing interactions and morphology of fatty acid methyl esters (biodiesel).

Berman P, Meiri N, Colnago LA, Moraes TB, Linder C, Levi O, Parmet Y, Saunders M, Wiesman Z.

Biotechnol Biofuels. 2015 Feb 4;8:12. doi: 10.1186/s13068-014-0194-7. eCollection 2015.


Emergence timing and fitness consequences of variation in seed oil composition in Arabidopsis thaliana.

Pelc SE, Linder CR.

Ecol Evol. 2015 Jan;5(1):164-71. doi: 10.1002/ece3.1265. Epub 2014 Dec 10.


Progress in lipid-based nanoparticles for cancer therapy.

Grinberg S, Linder C, Heldman E.

Crit Rev Oncog. 2014;19(3-4):247-60. Review.


Sandbox University: estimating influence of institutional action.

Forsman J, Mann RP, Linder C, van den Bogaard M.

PLoS One. 2014 Jul 23;9(7):e103261. doi: 10.1371/journal.pone.0103261. eCollection 2014. Erratum in: PLoS One. 2015;10(10):e0141705.


Intramuscular distribution of botulinum toxin--visualized by MRI.

Elwischger K, Kasprian G, Weber M, Meyerspeer M, Linder C, Auff E, Prayer D, Sycha T, Kranz G.

J Neurol Sci. 2014 Sep 15;344(1-2):76-9. doi: 10.1016/j.jns.2014.06.028. Epub 2014 Jun 21.


Steric environment around acetylcholine head groups of bolaamphiphilic nanovesicles influences the release rate of encapsulated compounds.

Stern A, Guidotti M, Shaubi E, Popov M, Linder C, Heldman E, Grinberg S.

Int J Nanomedicine. 2014 Jan 20;9:561-74. doi: 10.2147/IJN.S53563. eCollection 2014.


Delivery of analgesic peptides to the brain by nano-sized bolaamphiphilic vesicles made of monolayer membranes.

Popov M, Abu Hammad I, Bachar T, Grinberg S, Linder C, Stepensky D, Heldman E.

Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):381-9. doi: 10.1016/j.ejpb.2013.06.005. Epub 2013 Jun 18.


Bolaamphiphilic vesicles encapsulating iron oxide nanoparticles: new vehicles for magnetically targeted drug delivery.

Philosof-Mazor L, Dakwar GR, Popov M, Kolusheva S, Shames A, Linder C, Greenberg S, Heldman E, Stepensky D, Jelinek R.

Int J Pharm. 2013 Jun 25;450(1-2):241-9. doi: 10.1016/j.ijpharm.2013.04.017. Epub 2013 Apr 24.


In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery.

Kim T, Afonin KA, Viard M, Koyfman AY, Sparks S, Heldman E, Grinberg S, Linder C, Blumenthal RP, Shapiro BA.

Mol Ther Nucleic Acids. 2013 Mar 19;2:e80. doi: 10.1038/mtna.2013.5.


New point mutation in Golga3 causes multiple defects in spermatogenesis.

Bentson LF, Agbor VA, Agbor LN, Lopez AC, Nfonsam LE, Bornstein SS, Handel MA, Linder CC.

Andrology. 2013 May;1(3):440-50. doi: 10.1111/j.2047-2927.2013.00070.x. Epub 2013 Mar 15.


Enzymatic conversion of 6-nitroquinoline to the fluorophore 6-aminoquinoline selectively under hypoxic conditions.

Rajapakse A, Linder C, Morrison RD, Sarkar U, Leigh ND, Barnes CL, Daniels JS, Gates KS.

Chem Res Toxicol. 2013 Apr 15;26(4):555-63. doi: 10.1021/tx300483z. Epub 2013 Apr 2.


Fusion of bolaamphiphile micelles: a method to prepare stable supported biomimetic membranes.

Kaufman Y, Grinberg S, Linder C, Heldman E, Gilron J, Freger V.

Langmuir. 2013 Jan 29;29(4):1152-61. doi: 10.1021/la304484p. Epub 2013 Jan 11.


DACTAL: divide-and-conquer trees (almost) without alignments.

Nelesen S, Liu K, Wang LS, Linder CR, Warnow T.

Bioinformatics. 2012 Jun 15;28(12):i274-82. doi: 10.1093/bioinformatics/bts218.


Perfusion and flow extraction product as potential discriminators in untreated follicular and diffuse large B cell lymphomas using volume perfusion CT with attempt at histopathologic explanation.

Spira D, Adam P, Linder C, Spira SM, Pintoffl J, Claussen CD, Horger M.

AJR Am J Roentgenol. 2012 Jun;198(6):1239-46. doi: 10.2214/AJR.11.7858.


Applying mouse genetics expertise to research.

Linder C.

Lab Anim (NY). 2012 Apr 19;41(5):135. doi: 10.1038/laban0512-135. No abstract available.


Delivery of proteins to the brain by bolaamphiphilic nano-sized vesicles.

Dakwar GR, Abu Hammad I, Popov M, Linder C, Grinberg S, Heldman E, Stepensky D.

J Control Release. 2012 Jun 10;160(2):315-21. doi: 10.1016/j.jconrel.2011.12.042. Epub 2012 Jan 9.


Site-directed decapsulation of bolaamphiphilic vesicles with enzymatic cleavable surface groups.

Popov M, Grinberg S, Linder C, Waner T, Levi-Hevroni B, Deckelbaum RJ, Heldman E.

J Control Release. 2012 Jun 10;160(2):306-14. doi: 10.1016/j.jconrel.2011.12.022. Epub 2011 Dec 29.


SATe-II: very fast and accurate simultaneous estimation of multiple sequence alignments and phylogenetic trees.

Liu K, Warnow TJ, Holder MT, Nelesen SM, Yu J, Stamatakis AP, Linder CR.

Syst Biol. 2012 Jan;61(1):90-106. doi: 10.1093/sysbio/syr095. Epub 2011 Dec 1.


RAxML and FastTree: comparing two methods for large-scale maximum likelihood phylogeny estimation.

Liu K, Linder CR, Warnow T.

PLoS One. 2011;6(11):e27731. doi: 10.1371/journal.pone.0027731. Epub 2011 Nov 21.


Differential modulation of cytochrome P450 activity and the effect of 1-aminobenzotriazole on hepatic transport in sandwich-cultured human hepatocytes.

Kimoto E, Walsky R, Zhang H, Bi YA, Whalen KM, Yang YS, Linder C, Xiao Y, Iseki K, Fenner KS, El-Kattan AF, Lai Y.

Drug Metab Dispos. 2012 Feb;40(2):407-11. doi: 10.1124/dmd.111.039297. Epub 2011 Oct 26.

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