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Items: 1 to 50 of 54

1.

A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury.

Grigorieva IV, Oszwald A, Grigorieva EF, Schachner H, Neudert B, Ostendorf T, Floege J, Lindenmeyer MT, Cohen CD, Panzer U, Aigner C, Schmidt A, Grosveld F, Thakker RV, Rees AJ, Kain R.

J Am Soc Nephrol. 2019 Aug 12. pii: ASN.2018111143. doi: 10.1681/ASN.2018111143. [Epub ahead of print]

PMID:
31405951
2.

Interleukin-1β Inhibition for Chronic Kidney Disease in Obese Mice With Type 2 Diabetes.

Lei Y, Devarapu SK, Motrapu M, Cohen CD, Lindenmeyer MT, Moll S, Kumar SV, Anders HJ.

Front Immunol. 2019 May 29;10:1223. doi: 10.3389/fimmu.2019.01223. eCollection 2019.

3.

C-C chemokine receptor type 2 mediates glomerular injury and interstitial fibrosis in focal segmental glomerulosclerosis.

Wilkening A, Krappe J, Mühe AM, Lindenmeyer MT, Eltrich N, Luckow B, Vielhauer V.

Nephrol Dial Transplant. 2018 Dec 28. doi: 10.1093/ndt/gfy380. [Epub ahead of print]

PMID:
30597038
4.

Exclusive expression of transmembrane TNF aggravates acute glomerulonephritis despite reduced leukocyte infiltration and inflammation.

Müller MB, Hoppe JM, Bideak A, Lux M, Lindenmeyer MT, Müller S, Eltrich N, Ryffel B, Vielhauer V.

Kidney Int. 2019 Jan;95(1):75-93. doi: 10.1016/j.kint.2018.08.012. Epub 2018 Oct 30.

PMID:
30389199
5.

BDNF: mRNA expression in urine cells of patients with chronic kidney disease and its role in kidney function.

Endlich N, Lange T, Kuhn J, Klemm P, Kotb AM, Siegerist F, Kindt F, Lindenmeyer MT, Cohen CD, Kuss AW, Nath N, Rettig R, Lendeckel U, Zimmermann U, Amann K, Stracke S, Endlich K.

J Cell Mol Med. 2018 Nov;22(11):5265-5277. doi: 10.1111/jcmm.13762. Epub 2018 Aug 21.

6.

Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury.

Papakrivopoulou E, Vasilopoulou E, Lindenmeyer MT, Pacheco S, Brzóska HŁ, Price KL, Kolatsi-Joannou M, White KE, Henderson DJ, Dean CH, Cohen CD, Salama AD, Woolf AS, Long DA.

J Pathol. 2018 Dec;246(4):485-496. doi: 10.1002/path.5158.

7.

Metabolic pathways and immunometabolism in rare kidney diseases.

Grayson PC, Eddy S, Taroni JN, Lightfoot YL, Mariani L, Parikh H, Lindenmeyer MT, Ju W, Greene CS, Godfrey B, Cohen CD, Krischer J, Kretzler M, Merkel PA; Vasculitis Clinical Research Consortium, the European Renal cDNA Bank cohort, and the Nephrotic Syndrome Study Network.

Ann Rheum Dis. 2018 Aug;77(8):1226-1233. doi: 10.1136/annrheumdis-2017-212935. Epub 2018 May 3.

8.

The transcription factor Dach1 is essential for podocyte function.

Endlich N, Kliewe F, Kindt F, Schmidt K, Kotb AM, Artelt N, Lindenmeyer MT, Cohen CD, Döring F, Kuss AW, Amann K, Moeller MJ, Kabgani N, Blumenthal A, Endlich K.

J Cell Mol Med. 2018 May;22(5):2656-2669. doi: 10.1111/jcmm.13544. Epub 2018 Mar 2.

9.

Lymphotoxin expression in human and murine renal allografts.

Seeger H, Lindenmeyer MT, Cohen CD, Jaeckel C, Nelson PJ, Chen J, Edenhofer I, Kozakowski N, Regele H, Boehmig G, Brandt S, Wuethrich RP, Heikenwalder M, Fehr T, Segerer S.

PLoS One. 2018 Jan 4;13(1):e0189396. doi: 10.1371/journal.pone.0189396. eCollection 2018.

10.

Studying the role of fascin-1 in mechanically stressed podocytes.

Kliewe F, Scharf C, Rogge H, Darm K, Lindenmeyer MT, Amann K, Cohen CD, Endlich K, Endlich N.

Sci Rep. 2017 Aug 30;7(1):9916. doi: 10.1038/s41598-017-10116-4.

11.

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts.

Shved N, Warsow G, Eichinger F, Hoogewijs D, Brandt S, Wild P, Kretzler M, Cohen CD, Lindenmeyer MT.

Sci Rep. 2017 Aug 17;7(1):8576. doi: 10.1038/s41598-017-08492-y.

12.

Renal biopsy-driven molecular target identification in glomerular disease.

Lindenmeyer MT, Kretzler M.

Pflugers Arch. 2017 Aug;469(7-8):1021-1028. doi: 10.1007/s00424-017-2006-y. Epub 2017 Jun 29. Review.

PMID:
28664406
13.

Loss of endogenous thymosin β4 accelerates glomerular disease.

Vasilopoulou E, Kolatsi-Joannou M, Lindenmeyer MT, White KE, Robson MG, Cohen CD, Sebire NJ, Riley PR, Winyard PJ, Long DA.

Kidney Int. 2016 Nov;90(5):1056-1070. doi: 10.1016/j.kint.2016.06.032. Epub 2016 Aug 26.

14.

The Authors Reply.

Segerer S, Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Cohen CD, Neuhauss SCF, Loffing J.

Kidney Int. 2016 May;89(5):1161-1162. doi: 10.1016/j.kint.2015.10.020. No abstract available.

PMID:
27083290
15.

Keratins are novel markers of renal epithelial cell injury.

Djudjaj S, Papasotiriou M, Bülow RD, Wagnerova A, Lindenmeyer MT, Cohen CD, Strnad P, Goumenos DS, Floege J, Boor P.

Kidney Int. 2016 Apr;89(4):792-808. doi: 10.1016/j.kint.2015.10.015. Epub 2016 Feb 6.

PMID:
26924053
16.

Cathepsin S Cleavage of Protease-Activated Receptor-2 on Endothelial Cells Promotes Microvascular Diabetes Complications.

Kumar Vr S, Darisipudi MN, Steiger S, Devarapu SK, Tato M, Kukarni OP, Mulay SR, Thomasova D, Popper B, Demleitner J, Zuchtriegel G, Reichel C, Cohen CD, Lindenmeyer MT, Liapis H, Moll S, Reid E, Stitt AW, Schott B, Gruner S, Haap W, Ebeling M, Hartmann G, Anders HJ.

J Am Soc Nephrol. 2016 Jun;27(6):1635-49. doi: 10.1681/ASN.2015020208. Epub 2015 Nov 13.

17.

Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74.

Djudjaj S, Lue H, Rong S, Papasotiriou M, Klinkhammer BM, Zok S, Klaener O, Braun GS, Lindenmeyer MT, Cohen CD, Bucala R, Tittel AP, Kurts C, Moeller MJ, Floege J, Ostendorf T, Bernhagen J, Boor P.

J Am Soc Nephrol. 2016 Jun;27(6):1650-64. doi: 10.1681/ASN.2015020149. Epub 2015 Oct 9.

18.

The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier.

Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Segerer S, Cohen CD, Neuhauss SC, Loffing J.

Kidney Int. 2015 Nov;88(5):1047-56. doi: 10.1038/ki.2015.197. Epub 2015 Jul 8.

PMID:
26154927
19.

Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated by HIF-independent chromatin looping.

Schörg A, Santambrogio S, Platt JL, Schödel J, Lindenmeyer MT, Cohen CD, Schrödter K, Mole DR, Wenger RH, Hoogewijs D.

Nucleic Acids Res. 2015 Jul 13;43(12):5810-23. doi: 10.1093/nar/gkv506. Epub 2015 May 24.

20.

Alterations in the ubiquitin proteasome system in persistent but not reversible proteinuric diseases.

Beeken M, Lindenmeyer MT, Blattner SM, Radón V, Oh J, Meyer TN, Hildebrand D, Schlüter H, Reinicke AT, Knop JH, Vivekanandan-Giri A, Münster S, Sachs M, Wiech T, Pennathur S, Cohen CD, Kretzler M, Stahl RA, Meyer-Schwesinger C.

J Am Soc Nephrol. 2014 Nov;25(11):2511-25. doi: 10.1681/ASN.2013050522. Epub 2014 Apr 10.

21.

UCH-L1 induces podocyte hypertrophy in membranous nephropathy by protein accumulation.

Lohmann F, Sachs M, Meyer TN, Sievert H, Lindenmeyer MT, Wiech T, Cohen CD, Balabanov S, Stahl RA, Meyer-Schwesinger C.

Biochim Biophys Acta. 2014 Jul;1842(7):945-58. doi: 10.1016/j.bbadis.2014.02.011. Epub 2014 Feb 28.

22.

Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease.

Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, Ideker T, Kopp JB, Nigam SK, Cohen CD, Groop PH, Barshop BA, Natarajan L, Nyhan WL, Naviaux RK.

J Am Soc Nephrol. 2013 Nov;24(11):1901-12. doi: 10.1681/ASN.2013020126. Epub 2013 Oct 10.

23.

Distinct contributions of TNF receptor 1 and 2 to TNF-induced glomerular inflammation in mice.

Taubitz A, Schwarz M, Eltrich N, Lindenmeyer MT, Vielhauer V.

PLoS One. 2013 Jul 15;8(7):e68167. doi: 10.1371/journal.pone.0068167. Print 2013.

24.

Susceptibility of podocytes to palmitic acid is regulated by stearoyl-CoA desaturases 1 and 2.

Sieber J, Weins A, Kampe K, Gruber S, Lindenmeyer MT, Cohen CD, Orellana JM, Mundel P, Jehle AW.

Am J Pathol. 2013 Sep;183(3):735-44. doi: 10.1016/j.ajpath.2013.05.023. Epub 2013 Jul 16.

25.

Resistance to ABT-737 in activated T lymphocytes: molecular mechanisms and reversibility by inhibition of the calcineurin-NFAT pathway.

Cippà PE, Kraus AK, Lindenmeyer MT, Chen J, Guimezanes A, Bardwell PD, Wekerle T, Wüthrich RP, Fehr T.

Cell Death Dis. 2012 Apr 19;3:e299. doi: 10.1038/cddis.2012.38.

26.

Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy.

Brennan EP, Morine MJ, Walsh DW, Roxburgh SA, Lindenmeyer MT, Brazil DP, Gaora PÓ, Roche HM, Sadlier DM, Cohen CD; GENIE Consortium, Godson C, Martin F.

Biochim Biophys Acta. 2012 Apr;1822(4):589-99. doi: 10.1016/j.bbadis.2012.01.008. Epub 2012 Jan 14.

27.

Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.

Lichtnekert J, Kulkarni OP, Mulay SR, Rupanagudi KV, Ryu M, Allam R, Vielhauer V, Muruve D, Lindenmeyer MT, Cohen CD, Anders HJ.

PLoS One. 2011;6(10):e26778. doi: 10.1371/journal.pone.0026778. Epub 2011 Oct 27.

28.

Periostin is induced in glomerular injury and expressed de novo in interstitial renal fibrosis.

Sen K, Lindenmeyer MT, Gaspert A, Eichinger F, Neusser MA, Kretzler M, Segerer S, Cohen CD.

Am J Pathol. 2011 Oct;179(4):1756-67. doi: 10.1016/j.ajpath.2011.06.002. Epub 2011 Aug 18.

29.

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.

Gödel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, Lu S, Debreczeni-Mór A, Lindenmeyer MT, Rastaldi MP, Hartleben G, Wiech T, Fornoni A, Nelson RG, Kretzler M, Wanke R, Pavenstädt H, Kerjaschki D, Cohen CD, Hall MN, Rüegg MA, Inoki K, Walz G, Huber TB.

J Clin Invest. 2011 Jun;121(6):2197-209. doi: 10.1172/JCI44774. Epub 2011 May 23.

30.

Critical role of the calpain/calpastatin balance in acute allograft rejection.

Letavernier E, Dansou B, Lochner M, Perez J, Bellocq A, Lindenmeyer MT, Cohen CD, Haymann JP, Eberl G, Baud L.

Eur J Immunol. 2011 Feb;41(2):473-84. doi: 10.1002/eji.201040437. Epub 2010 Dec 23.

31.

Intrarenal production of B-cell survival factors in human lupus nephritis.

Neusser MA, Lindenmeyer MT, Edenhofer I, Gaiser S, Kretzler M, Regele H, Segerer S, Cohen CD.

Mod Pathol. 2011 Jan;24(1):98-107. doi: 10.1038/modpathol.2010.184. Epub 2010 Oct 1.

32.

Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids.

Sieber J, Lindenmeyer MT, Kampe K, Campbell KN, Cohen CD, Hopfer H, Mundel P, Jehle AW.

Am J Physiol Renal Physiol. 2010 Oct;299(4):F821-9. doi: 10.1152/ajprenal.00196.2010. Epub 2010 Jul 28.

33.

Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset.

Lindenmeyer MT, Eichinger F, Sen K, Anders HJ, Edenhofer I, Mattinzoli D, Kretzler M, Rastaldi MP, Cohen CD.

PLoS One. 2010 Jul 12;5(7):e11545. doi: 10.1371/journal.pone.0011545.

34.

Renal tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses.

Starke A, Lindenmeyer MT, Segerer S, Neusser MA, Rüsi B, Schmid DM, Cohen CD, Wüthrich RP, Fehr T, Waeckerle-Men Y.

Kidney Int. 2010 Jul;78(1):38-47. doi: 10.1038/ki.2010.97. Epub 2010 Apr 14.

35.

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice.

Hartleben B, Gödel M, Meyer-Schwesinger C, Liu S, Ulrich T, Köbler S, Wiech T, Grahammer F, Arnold SJ, Lindenmeyer MT, Cohen CD, Pavenstädt H, Kerjaschki D, Mizushima N, Shaw AS, Walz G, Huber TB.

J Clin Invest. 2010 Apr;120(4):1084-96. doi: 10.1172/JCI39492.

36.

Human nephrosclerosis triggers a hypoxia-related glomerulopathy.

Neusser MA, Lindenmeyer MT, Moll AG, Segerer S, Edenhofer I, Sen K, Stiehl DP, Kretzler M, Gröne HJ, Schlöndorff D, Cohen CD.

Am J Pathol. 2010 Feb;176(2):594-607. doi: 10.2353/ajpath.2010.090268. Epub 2009 Dec 17.

37.

Alterations of the podocyte proteome in response to high glucose concentrations.

Schordan S, Schordan E, Endlich N, Lindenmeyer MT, Meyer-Schwesinger C, Meyer TN, Giebel J, Cohen CD, Endlich K, Maurer MH.

Proteomics. 2009 Oct;9(19):4519-28. doi: 10.1002/pmic.200800214.

PMID:
19688724
38.

Wnt pathway regulation in chronic renal allograft damage.

von Toerne C, Schmidt C, Adams J, Kiss E, Bedke J, Porubsky S, Gretz N, Lindenmeyer MT, Cohen CD, Gröne HJ, Nelson PJ.

Am J Transplant. 2009 Oct;9(10):2223-39. doi: 10.1111/j.1600-6143.2009.02762.x. Epub 2009 Jul 22.

39.

Efficient renal recruitment of macrophages and T cells in mice lacking the duffy antigen/receptor for chemokines.

Vielhauer V, Allam R, Lindenmeyer MT, Cohen CD, Draganovici D, Mandelbaum J, Eltrich N, Nelson PJ, Anders HJ, Pruenster M, Rot A, Schlöndorff D, Segerer S.

Am J Pathol. 2009 Jul;175(1):119-31. doi: 10.2353/ajpath.2009.080590. Epub 2009 Jun 4.

40.

Patients with IgA nephropathy exhibit high systemic PDGF-DD levels.

Boor P, Eitner F, Cohen CD, Lindenmeyer MT; ERCB-Consortium, Mertens PR, Ostendorf T, Floege J.

Nephrol Dial Transplant. 2009 Sep;24(9):2755-62. doi: 10.1093/ndt/gfp152. Epub 2009 Apr 8.

41.

Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays.

Moll AG, Lindenmeyer MT, Kretzler M, Nelson PJ, Zimmer R, Cohen CD.

PLoS One. 2009;4(3):e4702. doi: 10.1371/journal.pone.0004702. Epub 2009 Mar 11.

42.

Proteinuria and hyperglycemia induce endoplasmic reticulum stress.

Lindenmeyer MT, Rastaldi MP, Ikehata M, Neusser MA, Kretzler M, Cohen CD, Schlöndorff D.

J Am Soc Nephrol. 2008 Nov;19(11):2225-36. doi: 10.1681/ASN.2007121313. Epub 2008 Sep 5.

43.

Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis.

Cohen CD, Lindenmeyer MT, Eichinger F, Hahn A, Seifert M, Moll AG, Schmid H, Kiss E, Gröne E, Gröne HJ, Kretzler M, Werner T, Nelson PJ.

PLoS One. 2008 Aug 13;3(8):e2937. doi: 10.1371/journal.pone.0002937.

44.

Genomic analysis in nephrology--towards systems biology and systematic medicine?

Neusser MA, Lindenmeyer MT, Kretzler M, Cohen CD.

Nephrol Ther. 2008 Oct;4(5):306-11. doi: 10.1016/j.nephro.2008.04.003. Epub 2008 Jun 30. Review.

45.

Compartment specific expression of dendritic cell markers in human glomerulonephritis.

Segerer S, Heller F, Lindenmeyer MT, Schmid H, Cohen CD, Draganovici D, Mandelbaum J, Nelson PJ, Gröne HJ, Gröne EF, Figel AM, Nössner E, Schlöndorff D.

Kidney Int. 2008 Jul;74(1):37-46. doi: 10.1038/ki.2008.99. Epub 2008 Mar 26.

46.

Collagen type VIII expression in human diabetic nephropathy.

Gerth J, Cohen CD, Hopfer U, Lindenmeyer MT, Sommer M, Gröne HJ, Wolf G.

Eur J Clin Invest. 2007 Oct;37(10):767-73.

PMID:
17888087
47.

Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy.

Lindenmeyer MT, Kretzler M, Boucherot A, Berra S, Yasuda Y, Henger A, Eichinger F, Gaiser S, Schmid H, Rastaldi MP, Schrier RW, Schlöndorff D, Cohen CD.

J Am Soc Nephrol. 2007 Jun;18(6):1765-76. Epub 2007 May 2.

48.

Microarray analysis reveals influence of the sesquiterpene lactone parthenolide on gene transcription profiles in human epithelial cells.

Lindenmeyer MT, Kern C, Sparna T, Donauer J, Wilpert J, Schwager J, Porath D, Kreutz C, Timmer J, Merfort I.

Life Sci. 2007 Apr 3;80(17):1608-18. Epub 2007 Jan 27.

PMID:
17343877
49.

The contribution of B cells to renal interstitial inflammation.

Heller F, Lindenmeyer MT, Cohen CD, Brandt U, Draganovici D, Fischereder M, Kretzler M, Anders HJ, Sitter T, Mosberger I, Kerjaschki D, Regele H, Schlöndorff D, Segerer S.

Am J Pathol. 2007 Feb;170(2):457-68.

50.

Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells.

Lindenmeyer MT, Hrenn A, Kern C, Castro V, Murillo R, Müller S, Laufer S, Schulte-Mönting J, Siedle B, Merfort I.

Bioorg Med Chem. 2006 Apr 15;14(8):2487-97. Epub 2005 Dec 1.

PMID:
16326104

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