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Items: 1 to 50 of 60

1.

MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.

Kumar S, Barouch-Bentov R, Xiao F, Schor S, Pu S, Biquand E, Lu A, Lindenbach BD, Jacob Y, Demeret C, Einav S.

Cell Rep. 2019 Feb 12;26(7):1800-1814.e5. doi: 10.1016/j.celrep.2019.01.075.

2.

Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release.

Xiao F, Wang S, Barouch-Bentov R, Neveu G, Pu S, Beer M, Schor S, Kumar S, Nicolaescu V, Lindenbach BD, Randall G, Einav S.

MBio. 2018 Mar 13;9(2). pii: e02233-17. doi: 10.1128/mBio.02233-17.

3.

Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies.

Bartenschlager R, Baumert TF, Bukh J, Houghton M, Lemon SM, Lindenbach BD, Lohmann V, Moradpour D, Pietschmann T, Rice CM, Thimme R, Wakita T.

Virus Res. 2018 Mar 15;248:53-62. doi: 10.1016/j.virusres.2018.02.016. Epub 2018 Mar 2. Review.

4.

Recovery of Infectious Hepatitis C Virus From Injection Paraphernalia: Implications for Prevention Programs Serving People Who Inject Drugs.

Heimer R, Binka M, Koester S, Grund JC, Patel A, Paintsil E, Lindenbach BD.

J Infect Dis. 2018 Jan 17;217(3):466-473. doi: 10.1093/infdis/jix427.

5.

IRE1α promotes viral infection by conferring resistance to apoptosis.

Fink SL, Jayewickreme TR, Molony RD, Iwawaki T, Landis CS, Lindenbach BD, Iwasaki A.

Sci Signal. 2017 Jun 6;10(482). pii: eaai7814. doi: 10.1126/scisignal.aai7814.

6.

Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil.

Donald CL, Brennan B, Cumberworth SL, Rezelj VV, Clark JJ, Cordeiro MT, Freitas de Oliveira França R, Pena LJ, Wilkie GS, Da Silva Filipe A, Davis C, Hughes J, Varjak M, Selinger M, Zuvanov L, Owsianka AM, Patel AH, McLauchlan J, Lindenbach BD, Fall G, Sall AA, Biek R, Rehwinkel J, Schnettler E, Kohl A.

PLoS Negl Trop Dis. 2016 Oct 5;10(10):e0005048. doi: 10.1371/journal.pntd.0005048. eCollection 2016 Oct.

7.

Zika virus productively infects primary human placenta-specific macrophages.

Jurado KA, Simoni MK, Tang Z, Uraki R, Hwang J, Householder S, Wu M, Lindenbach BD, Abrahams VM, Guller S, Fikrig E.

JCI Insight. 2016 Aug 18;1(13). pii: e88461.

8.

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia.

Onorati M, Li Z, Liu F, Sousa AMM, Nakagawa N, Li M, Dell'Anno MT, Gulden FO, Pochareddy S, Tebbenkamp ATN, Han W, Pletikos M, Gao T, Zhu Y, Bichsel C, Varela L, Szigeti-Buck K, Lisgo S, Zhang Y, Testen A, Gao XB, Mlakar J, Popovic M, Flamand M, Strittmatter SM, Kaczmarek LK, Anton ES, Horvath TL, Lindenbach BD, Sestan N.

Cell Rep. 2016 Sep 6;16(10):2576-2592. doi: 10.1016/j.celrep.2016.08.038. Epub 2016 Aug 24.

9.

Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.

Yockey LJ, Varela L, Rakib T, Khoury-Hanold W, Fink SL, Stutz B, Szigeti-Buck K, Van den Pol A, Lindenbach BD, Horvath TL, Iwasaki A.

Cell. 2016 Aug 25;166(5):1247-1256.e4. doi: 10.1016/j.cell.2016.08.004.

10.

The Coding Region of the HCV Genome Contains a Network of Regulatory RNA Structures.

Pirakitikulr N, Kohlway A, Lindenbach BD, Pyle AM.

Mol Cell. 2016 Apr 7;62(1):111-20. doi: 10.1016/j.molcel.2016.01.024. Epub 2016 Feb 25.

11.

What's next for hepatitis C virus research?

Lindenbach BD.

Hepatology. 2016 May;63(5):1408-10. doi: 10.1002/hep.28494. Epub 2016 Mar 19. No abstract available.

PMID:
26853717
12.

Correction: A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication.

Isken O, Langerwisch U, Jirasko V, Rehders D, Redecke L, Ramanathan H, Lindenbach BD, Bartenschlager R, Tautz N.

PLoS Pathog. 2016 Jan 8;12(1):e1005394. doi: 10.1371/journal.ppat.1005394. eCollection 2016 Jan.

13.

Correction: Survival of Hepatitis C Virus in Syringes Is Dependent on the Design of the Syringe-Needle and Dead Space Volume.

Binka M, Paintsil E, Patel A, Lindenbach BD, Heimer R.

PLoS One. 2015 Dec 23;10(12):e0146088. doi: 10.1371/journal.pone.0146088. eCollection 2015. No abstract available.

14.

Survival of Hepatitis C Virus in Syringes Is Dependent on the Design of the Syringe-Needle and Dead Space Volume.

Binka M, Paintsil E, Patel A, Lindenbach BD, Heimer R.

PLoS One. 2015 Nov 4;10(11):e0139737. doi: 10.1371/journal.pone.0139737. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0146088.

15.

Disinfection of syringes contaminated with hepatitis C virus by rinsing with household products.

Binka M, Paintsil E, Patel A, Lindenbach BD, Heimer R.

Open Forum Infect Dis. 2015 Feb 23;2(1):ofv017. doi: 10.1093/ofid/ofv017. eCollection 2015 Jan.

16.

Hepatitis C virus RNA replication depends on specific cis- and trans-acting activities of viral nonstructural proteins.

Kazakov T, Yang F, Ramanathan HN, Kohlway A, Diamond MS, Lindenbach BD.

PLoS Pathog. 2015 Apr 13;11(4):e1004817. doi: 10.1371/journal.ppat.1004817. eCollection 2015 Apr.

17.

A conserved NS3 surface patch orchestrates NS2 protease stimulation, NS5A hyperphosphorylation and HCV genome replication.

Isken O, Langerwisch U, Jirasko V, Rehders D, Redecke L, Ramanathan H, Lindenbach BD, Bartenschlager R, Tautz N.

PLoS Pathog. 2015 Mar 16;11(3):e1004736. doi: 10.1371/journal.ppat.1004736. eCollection 2015 Mar. Erratum in: PLoS Pathog. 2016 Jan;12(1):e1005394.

18.

Expanding the proteome of an RNA virus by phosphorylation of an intrinsically disordered viral protein.

Cordek DG, Croom-Perez TJ, Hwang J, Hargittai MR, Subba-Reddy CV, Han Q, Lodeiro MF, Ning G, McCrory TS, Arnold JJ, Koc H, Lindenbach BD, Showalter SA, Cameron CE.

J Biol Chem. 2014 Aug 29;289(35):24397-416. doi: 10.1074/jbc.M114.589911. Epub 2014 Jul 16.

19.

The linker region of NS3 plays a critical role in the replication and infectivity of hepatitis C virus.

Kohlway A, Pirakitikulr N, Ding SC, Yang F, Luo D, Lindenbach BD, Pyle AM.

J Virol. 2014 Sep;88(18):10970-4. doi: 10.1128/JVI.00745-14. Epub 2014 Jun 25.

20.

Hepatitis C virus maintains infectivity for weeks after drying on inanimate surfaces at room temperature: implications for risks of transmission.

Paintsil E, Binka M, Patel A, Lindenbach BD, Heimer R.

J Infect Dis. 2014 Apr 15;209(8):1205-11. doi: 10.1093/infdis/jit648. Epub 2013 Nov 23.

21.

Hepatitis C virus RNA replication and virus particle assembly require specific dimerization of the NS4A protein transmembrane domain.

Kohlway A, Pirakitikulr N, Barrera FN, Potapova O, Engelman DM, Pyle AM, Lindenbach BD.

J Virol. 2014 Jan;88(1):628-42. doi: 10.1128/JVI.02052-13. Epub 2013 Oct 30.

22.

The ins and outs of hepatitis C virus entry and assembly.

Lindenbach BD, Rice CM.

Nat Rev Microbiol. 2013 Oct;11(10):688-700. doi: 10.1038/nrmicro3098. Epub 2013 Sep 10. Review.

23.

Virion assembly and release.

Lindenbach BD.

Curr Top Microbiol Immunol. 2013;369:199-218. doi: 10.1007/978-3-642-27340-7_8. Review.

24.

A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses.

Polyak SJ, Morishima C, Scott JD, Gastaminza P, Cox A, de Araújo ES, Higgs MR, Loo YM, Golden-Mason L, Lindenbach BD, Baumert TF, Randall G, Gale M Jr.

Gastroenterology. 2012 Jan;142(1):e1-5. doi: 10.1053/j.gastro.2011.11.002. No abstract available. Erratum in: Gastroenterology. 2012 Feb;142(2):411. Gastaminza, Pablo [added].

PMID:
22185796
25.

Trafficking of hepatitis C virus core protein during virus particle assembly.

Counihan NA, Rawlinson SM, Lindenbach BD.

PLoS Pathog. 2011 Oct;7(10):e1002302. doi: 10.1371/journal.ppat.1002302. Epub 2011 Oct 20.

26.

Structural insights into RNA recognition by RIG-I.

Luo D, Ding SC, Vela A, Kohlway A, Lindenbach BD, Pyle AM.

Cell. 2011 Oct 14;147(2):409-22. doi: 10.1016/j.cell.2011.09.023.

27.

Understanding how hepatitis C virus builds its unctuous home.

Lindenbach BD.

Cell Host Microbe. 2011 Jan 20;9(1):1-2. doi: 10.1016/j.chom.2011.01.002.

28.

Hepatitis C virus NS2 coordinates virus particle assembly through physical interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes.

Stapleford KA, Lindenbach BD.

J Virol. 2011 Feb;85(4):1706-17. doi: 10.1128/JVI.02268-10. Epub 2010 Dec 8.

29.

The acidic domain of hepatitis C virus NS4A contributes to RNA replication and virus particle assembly.

Phan T, Kohlway A, Dimberu P, Pyle AM, Lindenbach BD.

J Virol. 2011 Feb;85(3):1193-204. doi: 10.1128/JVI.01889-10. Epub 2010 Nov 3.

30.

New cell culture models of hepatitis C virus entry, replication, and virus production.

Lindenbach BD.

Gastroenterology. 2010 Oct;139(4):1090-3. doi: 10.1053/j.gastro.2010.08.014. Epub 2010 Aug 24. No abstract available.

PMID:
20797436
31.

Survival of hepatitis C virus in syringes: implication for transmission among injection drug users.

Paintsil E, He H, Peters C, Lindenbach BD, Heimer R.

J Infect Dis. 2010 Oct 1;202(7):984-90. doi: 10.1086/656212.

32.

An implantable vascularized protein gel construct that supports human fetal hepatoblast survival and infection by hepatitis C virus in mice.

Harding MJ, Lepus CM, Gibson TF, Shepherd BR, Gerber SA, Graham M, Paturzo FX, Rahner C, Madri JA, Bothwell AL, Lindenbach BD, Pober JS.

PLoS One. 2010 Apr 1;5(4):e9987. doi: 10.1371/journal.pone.0009987.

33.

A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitro.

Cheng Y, Tsou LK, Cai J, Aya T, Dutschman GE, Gullen EA, Grill SP, Chen AP, Lindenbach BD, Hamilton AD, Cheng YC.

Antimicrob Agents Chemother. 2010 Jan;54(1):197-206. doi: 10.1128/AAC.01206-09. Epub 2009 Nov 9.

34.

Gumming up the works: DNA polymers as HCV entry inhibitors.

Counihan NA, Lindenbach BD.

Gastroenterology. 2009 Aug;137(2):427-30. doi: 10.1053/j.gastro.2009.06.018. Epub 2009 Jun 27. No abstract available.

35.

Hepatitis C virus NS2 protein contributes to virus particle assembly via opposing epistatic interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes.

Phan T, Beran RK, Peters C, Lorenz IC, Lindenbach BD.

J Virol. 2009 Sep;83(17):8379-95. doi: 10.1128/JVI.00891-09. Epub 2009 Jun 10.

36.

The NS4A protein of hepatitis C virus promotes RNA-coupled ATP hydrolysis by the NS3 helicase.

Beran RK, Lindenbach BD, Pyle AM.

J Virol. 2009 Apr;83(7):3268-75. doi: 10.1128/JVI.01849-08. Epub 2009 Jan 19.

37.

Measuring HCV infectivity produced in cell culture and in vivo.

Lindenbach BD.

Methods Mol Biol. 2009;510:329-36. doi: 10.1007/978-1-59745-394-3_24.

PMID:
19009272
38.

Reverse transcription PCR-based sequence analysis of hepatitis C virus replicon RNA.

Tellinghuisen TL, Lindenbach BD.

Methods Mol Biol. 2009;510:165-75. doi: 10.1007/978-1-59745-394-3_12.

PMID:
19009260
39.

Cellular cofactors affecting hepatitis C virus infection and replication.

Randall G, Panis M, Cooper JD, Tellinghuisen TL, Sukhodolets KE, Pfeffer S, Landthaler M, Landgraf P, Kan S, Lindenbach BD, Chien M, Weir DB, Russo JJ, Ju J, Brownstein MJ, Sheridan R, Sander C, Zavolan M, Tuschl T, Rice CM.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12884-9. Epub 2007 Jul 6.

40.

The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication.

Lindenbach BD, Prágai BM, Montserret R, Beran RK, Pyle AM, Penin F, Rice CM.

J Virol. 2007 Sep;81(17):8905-18. Epub 2007 Jun 20.

41.

Superinfection exclusion in cells infected with hepatitis C virus.

Tscherne DM, Evans MJ, von Hahn T, Jones CT, Stamataki Z, McKeating JA, Lindenbach BD, Rice CM.

J Virol. 2007 Apr;81(8):3693-703. Epub 2007 Feb 7.

42.

Silencing of USP18 potentiates the antiviral activity of interferon against hepatitis C virus infection.

Randall G, Chen L, Panis M, Fischer AK, Lindenbach BD, Sun J, Heathcote J, Rice CM, Edwards AM, McGilvray ID.

Gastroenterology. 2006 Nov;131(5):1584-91. Epub 2006 Aug 22.

PMID:
17101330
43.

Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells.

von Hahn T, Lindenbach BD, Boullier A, Quehenberger O, Paulson M, Rice CM, McKeating JA.

Hepatology. 2006 May;43(5):932-42.

PMID:
16628670
44.

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro.

Lindenbach BD, Meuleman P, Ploss A, Vanwolleghem T, Syder AJ, McKeating JA, Lanford RE, Feinstone SM, Major ME, Leroux-Roels G, Rice CM.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3805-9. Epub 2006 Feb 16.

45.

Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry.

Tscherne DM, Jones CT, Evans MJ, Lindenbach BD, McKeating JA, Rice CM.

J Virol. 2006 Feb;80(4):1734-41.

46.

Unravelling hepatitis C virus replication from genome to function.

Lindenbach BD, Rice CM.

Nature. 2005 Aug 18;436(7053):933-8. Review.

PMID:
16107832
47.

Complete replication of hepatitis C virus in cell culture.

Lindenbach BD, Evans MJ, Syder AJ, Wölk B, Tellinghuisen TL, Liu CC, Maruyama T, Hynes RO, Burton DR, McKeating JA, Rice CM.

Science. 2005 Jul 22;309(5734):623-6. Epub 2005 Jun 9.

48.

Identification of microRNAs of the herpesvirus family.

Pfeffer S, Sewer A, Lagos-Quintana M, Sheridan R, Sander C, Grässer FA, van Dyk LF, Ho CK, Shuman S, Chien M, Russo JJ, Ju J, Randall G, Lindenbach BD, Rice CM, Simon V, Ho DD, Zavolan M, Tuschl T.

Nat Methods. 2005 Apr;2(4):269-76. Epub 2005 Feb 16.

PMID:
15782219
49.

Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes.

Moradpour D, Evans MJ, Gosert R, Yuan Z, Blum HE, Goff SP, Lindenbach BD, Rice CM.

J Virol. 2004 Jul;78(14):7400-9.

50.

Molecular biology of flaviviruses.

Lindenbach BD, Rice CM.

Adv Virus Res. 2003;59:23-61. Review. No abstract available.

PMID:
14696326

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