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Items: 1 to 50 of 677

1.

Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice.

Adão-Novaes J, Valverde RHF, Landemberger MC, Silveira MS, Simões-Pires EN, Lowe J, Linden R.

Brain Res. 2019 Nov 11:146550. doi: 10.1016/j.brainres.2019.146550. [Epub ahead of print]

PMID:
31726043
2.

A subacute model of glaucoma based on limbal plexus cautery in pigmented rats.

Lani R, Dias MS, Abreu CA, Araújo VG, Gonçalo T, Nascimento-Dos-Santos G, Dantas AM, Allodi S, Fiorani M, Petrs-Silva H, Linden R.

Sci Rep. 2019 Nov 8;9(1):16286. doi: 10.1038/s41598-019-52500-2.

3.

Cell Type Purification by Single-Cell Transcriptome-Trained Sorting.

Baron CS, Barve A, Muraro MJ, van der Linden R, Dharmadhikari G, Lyubimova A, de Koning EJP, van Oudenaarden A.

Cell. 2019 Oct 3;179(2):527-542.e19. doi: 10.1016/j.cell.2019.08.006.

4.

Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat.

Dias MS, Araujo VG, Vasconcelos T, Li Q, Hauswirth WW, Linden R, Petrs-Silva H.

Gene Ther. 2019 Sep 27. doi: 10.1038/s41434-019-0100-9. [Epub ahead of print]

PMID:
31562387
5.

De novo genesis of retinal ganglion cells by targeted expression of Klf4 in vivo.

Rocha-Martins M, de Toledo BC, Santos-França PL, Oliveira-Valença VM, Vieira-Vieira CH, Matos-Rodrigues GE, Linden R, Norden C, Martins RAP, Silveira MS.

Development. 2019 Aug 21;146(16). pii: dev176586. doi: 10.1242/dev.176586.

PMID:
31405994
6.

Official International Association for Therapeutic Drug Monitoring and Clinical Toxicology Guideline: Development and Validation of Dried Blood Spot-Based Methods for Therapeutic Drug Monitoring.

Capiau S, Veenhof H, Koster RA, Bergqvist Y, Boettcher M, Halmingh O, Keevil BG, Koch BCP, Linden R, Pistos C, Stolk LM, Touw DJ, Stove CP, Alffenaar JC.

Ther Drug Monit. 2019 Aug;41(4):409-430. doi: 10.1097/FTD.0000000000000643.

PMID:
31268966
7.

Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease.

Rosenblad C, Li Q, Pioli EY, Dovero S, Antunes AS, Agúndez L, Bardelli M, Linden RM, Henckaerts E, Björklund A, Bezard E, Björklund T.

Brain. 2019 Aug 1;142(8):2402-2416. doi: 10.1093/brain/awz176.

8.

Ready for TDM: Simultaneous quantification of amikacin, vancomycin and creatinine in human plasma employing ultra-performance liquid chromatography-tandem mass spectrometry.

da Silva ACC, de Lima Feltraco Lizot L, Bastiani MF, Antunes MV, Brucker N, Linden R.

Clin Biochem. 2019 Aug;70:39-45. doi: 10.1016/j.clinbiochem.2019.06.011. Epub 2019 Jun 20.

PMID:
31228434
9.

Simultaneous Determination of Cocaine and Metabolites in Human Plasma Using Solid Phase Micro-Extraction Fiber Tips C18 and UPLC-MS/MS.

Lizot LLF, da Silva ACC, Bastiani MF, Maurer TF, Hahn RZ, Perassolo MS, Antunes MV, Linden R.

J Anal Toxicol. 2019 May 16. pii: bkz042. doi: 10.1093/jat/bkz042. [Epub ahead of print]

PMID:
31095712
10.

Colorectal metastasis to the gallbladder mimicking a primary gallbladder malignancy: histopathological and molecular characteristics.

de Bitter TJJ, van der Linden RLA, van Vliet S, Weren F, Sie D, Ylstra B, van der Linden HC, Knijn N, Ligtenberg MJL, van der Post RS, Simmer F, Nagtegaal ID.

Histopathology. 2019 Sep;75(3):394-404. doi: 10.1111/his.13892. Epub 2019 Jul 18.

11.

An Improved Adeno-Associated Virus Vector for Neurological Correction of the Mouse Model of Mucopolysaccharidosis IIIA.

Gray AL, O'Leary C, Liao A, Agúndez L, Youshani AS, Gleitz HF, Parker H, Taylor JT, Danos O, Hocquemiller M, Palomar N, Linden RM, Henckaerts E, Holley RJ, Bigger BW.

Hum Gene Ther. 2019 Sep;30(9):1052-1066. doi: 10.1089/hum.2018.189. Epub 2019 Jun 4.

PMID:
31020862
12.

Simultaneous determination of cocaine, ecgonine methyl ester, benzoylecgonine, cocaethylene and norcocaine in dried blood spots by ultra-performance liquid chromatography coupled to tandem mass spectrometry.

de Lima Feltraco Lizot L, da Silva ACC, Bastiani MF, Hahn RZ, Bulcão R, Perassolo MS, Antunes MV, Linden R.

Forensic Sci Int. 2019 May;298:408-416. doi: 10.1016/j.forsciint.2019.03.026. Epub 2019 Mar 23.

PMID:
30954922
13.

Understanding Real-Time Fluorescence Signals from Bacteria and Wound Tissues Observed with the MolecuLight i:XTM.

Rennie MY, Dunham D, Lindvere-Teene L, Raizman R, Hill R, Linden R.

Diagnostics (Basel). 2019 Feb 26;9(1). pii: E22. doi: 10.3390/diagnostics9010022.

14.

Determination of Endogenous Concentrations of Uracil and Dihydrouracil in Dried Saliva Spots by LC-MS/MS: Method Development, Validation, and Clinical Application.

Antunes MV, Raymundo S, Cezimbra da Silva AC, Muller VV, Vicente Neto OJ, Schwartsmann G, Linden R.

Ther Drug Monit. 2019 Jun;41(3):383-390. doi: 10.1097/FTD.0000000000000615.

PMID:
30807536
15.

Simultaneous determination of vancomycin and creatinine in plasma applied to volumetric absorptive microsampling devices using liquid chromatography-tandem mass spectrometry.

Andriguetti NB, Lisboa LL, Hahn SR, Pagnussat LR, Antunes MV, Linden R.

J Pharm Biomed Anal. 2019 Feb 20;165:315-324. doi: 10.1016/j.jpba.2018.12.023. Epub 2018 Dec 14.

PMID:
30579232
16.

HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer.

Cioni B, Jordanova ES, Hooijberg E, van der Linden R, de Menezes RX, Tan K, Willems S, Elbers JBW, Broeks A, Bergman AM, Zuur CL, de Boer JP.

Head Neck. 2019 Feb;41(2):463-478. doi: 10.1002/hed.25442. Epub 2018 Dec 14.

17.

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival.

Sobral-Leite M, Van de Vijver K, Michaut M, van der Linden R, Hooijer GKJ, Horlings HM, Severson TM, Mulligan AM, Weerasooriya N, Sanders J, Glas AM, Wehkamp D, Mittempergher L, Kersten K, Cimino-Mathews A, Peters D, Hooijberg E, Broeks A, van de Vijver MJ, Bernards R, Andrulis IL, Kok M, de Visser KE, Schmidt MK.

Oncoimmunology. 2018 Sep 11;7(12):e1509820. doi: 10.1080/2162402X.2018.1509820. eCollection 2018.

18.

Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2.

Guimarães RPM, Landeira BS, Coelho DM, Golbert DCF, Silveira MS, Linden R, de Melo Reis RA, Costa MR.

Front Cell Neurosci. 2018 Nov 12;12:410. doi: 10.3389/fncel.2018.00410. eCollection 2018.

19.

Ecotoxicological risk assessment due to the presence of bisphenol A and caffeine in surface waters in the Sinos River Basin - Rio Grande do Sul - Brazil.

Peteffi GP, Fleck JD, Kael IM, Rosa DC, Antunes MV, Linden R.

Braz J Biol. 2019 Oct-Dec;79(4):712. doi: 10.1590/1519-6984.189752. Epub 2018 Nov 8.

20.

Increase of global DNA methylation patterns in beauty salon workers exposed to low levels of formaldehyde.

Barbosa E, Dos Santos ALA, Peteffi GP, Schneider A, Müller D, Rovaris D, Bau CHD, Linden R, Antunes MV, Charão MF.

Environ Sci Pollut Res Int. 2019 Jan;26(2):1304-1314. doi: 10.1007/s11356-018-3674-7. Epub 2018 Nov 12.

PMID:
30421373
21.

Rapid plasticity of intact axons following a lesion to the visual pathways during early brain development is triggered by microglial activation.

Chagas LDS, Trindade P, Gomes ALT, Mendonça HR, Campello-Costa P, Faria Melibeu ADC, Linden R, Serfaty CA.

Exp Neurol. 2019 Jan;311:148-161. doi: 10.1016/j.expneurol.2018.10.002. Epub 2018 Oct 9.

PMID:
30312606
22.

Health-Related Quality of Life in Patients with Small Intestine Neuroendocrine Tumors.

Karppinen N, Lindén R, Sintonen H, Tarkkanen M, Roine R, Heiskanen I, Matikainen N, Schalin-Jäntti C.

Neuroendocrinology. 2018;107(4):366-374. doi: 10.1159/000494293. Epub 2018 Oct 5.

PMID:
30293074
23.

Massive uterine lipoleiomyoma and leiomyoma in a miniature poodle bitch.

Percival A, Singh A, Zur Linden RA, Watrous G, Patten S, Valverde A, Ratsep E.

Can Vet J. 2018 Aug;59(8):845-850.

24.

Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus.

Agúndez L, Zárate-Pérez F, Meier AF, Bardelli M, Llosa M, Escalante CR, Linden RM, Henckaerts E.

PLoS One. 2018 Jul 17;13(7):e0200841. doi: 10.1371/journal.pone.0200841. eCollection 2018.

25.

Pharmacokinetic and Pharmacogenetic Markers of Irinotecan Toxicity.

Hahn RZ, Antunes MV, Verza SG, Perassolo MS, Suyenaga ES, Schwartsmann G, Linden R.

Curr Med Chem. 2019;26(12):2085-2107. doi: 10.2174/0929867325666180622141101. Review.

PMID:
29932028
26.

Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.

van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J.

Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150.

27.

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency.

Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, Dridi L, Martins C, Levade T, Stacey KB, Davis DM, Dyer A, Clément N, Björklund T, Ali RR, Agbandje-McKenna M, Rahim AA, Pshezhetsky A, Waddington SN, Linden RM, Bigger BW, Henckaerts E.

Brain. 2018 Jul 1;141(7):2014-2031. doi: 10.1093/brain/awy126.

28.

Determination of docetaxel in dried blood spots by LC-MS/MS: Method development, validation and clinical application.

Raymundo S, Muller VV, Andriguetti NB, Tegner M, Artmann AC, Kluck HM, Franzoi MA, Vilela RMM, Schwartsmann G, Linden R, Antunes MV.

J Pharm Biomed Anal. 2018 Aug 5;157:84-91. doi: 10.1016/j.jpba.2018.05.011. Epub 2018 May 17.

PMID:
29775811
29.

DPD functional tests in plasma, fresh saliva and dried saliva samples as predictors of 5-fluorouracil exposure and occurrence of drug-related severe toxicity.

Neto OV, Raymundo S, Franzoi MA, do Carmo Artmann A, Tegner M, Müller VV, Hahn RZ, Alves GV, Schwartsmann G, Linden R, Antunes MV.

Clin Biochem. 2018 Jun;56:18-25. doi: 10.1016/j.clinbiochem.2018.04.001. Epub 2018 Apr 4.

PMID:
29625079
30.

Caffeine levels as a predictor of Human mastadenovirus presence in surface waters-a case study in the Sinos River basin-Brazil.

Peteffi GP, Fleck JD, Kael IM, Girardi V, Bündchen R, Krajeski DM, Demoliner M, Silva FP, da Rosa DC, Antunes MV, Linden R.

Environ Sci Pollut Res Int. 2018 Jun;25(16):15774-15784. doi: 10.1007/s11356-018-1649-3. Epub 2018 Mar 26.

PMID:
29582324
31.

Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome.

Smith-Moore S, Neil SJD, Fraefel C, Linden RM, Bollen M, Rowe HM, Henckaerts E.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3529-E3538. doi: 10.1073/pnas.1721883115. Epub 2018 Mar 26.

32.

Analytical and clinical validation of a dried blood spot assay for the determination of paclitaxel using high-performance liquid chromatography-tandem mass spectrometry.

Andriguetti NB, Hahn RZ, Lizot LF, Raymundo S, Costa JL, da Cunha KF, Vilela RMM, Kluck HM, Schwartsmann G, Antunes MV, Linden R.

Clin Biochem. 2018 Apr;54:123-130. doi: 10.1016/j.clinbiochem.2018.02.020. Epub 2018 Mar 4.

PMID:
29514052
33.

Characterization of imatinib mesylate formulations distributed in South American countries: Determination of genotoxic impurities by UHPLC-MS/MS and dissolution profile.

Wolff FC, Dillenburg TL, Venzon Antunes M, Linden R, Comparsi Wagner S, Verza SG.

Biomed Chromatogr. 2018 Jul;32(7):e4222. doi: 10.1002/bmc.4222. Epub 2018 Apr 6.

PMID:
29488235
34.

In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate.

Eich C, Arlt J, Vink CS, Solaimani Kartalaei P, Kaimakis P, Mariani SA, van der Linden R, van Cappellen WA, Dzierzak E.

J Exp Med. 2018 Jan 2;215(1):233-248. doi: 10.1084/jem.20170807. Epub 2017 Dec 7.

35.

Determination of irinotecan and its metabolite SN-38 in dried blood spots using high-performance liquid-chromatography with fluorescence detection.

Hahn RZ, Arnhold PC, Andriguetti NB, Schneider A, Klück HM, Dos Reis SL, Bastiani MF, Kael I, da Silva ACC, Schwartsmann G, Antunes MV, Linden R.

J Pharm Biomed Anal. 2018 Feb 20;150:51-58. doi: 10.1016/j.jpba.2017.11.079. Epub 2017 Dec 5.

PMID:
29216585
36.

Cellular effects of thirdhand tobacco smoke from smokers' homes.

Figueiró LR, Linden R, Ziulkoski AL, Dantas DCM.

Toxicol Mech Methods. 2018 May;28(4):243-251. doi: 10.1080/15376516.2017.1411411. Epub 2017 Dec 7.

PMID:
29185369
37.

Simultaneous determination of fluoxetine and norfluoxetine in dried blood spots using high-performance liquid chromatography-tandem mass spectrometry.

da Silva ACC, Raasch JR, Vargas TG, Peteffi GP, Hahn RZ, Antunes MV, Perassolo MS, Linden R.

Clin Biochem. 2018 Feb;52:85-93. doi: 10.1016/j.clinbiochem.2017.10.002. Epub 2017 Oct 5.

PMID:
28987790
38.

Accuracy of preoperative MRI to assess lateral neck metastases in papillary thyroid carcinoma.

Renkonen S, Lindén R, Bäck L, Silén R, Mäenpää H, Tapiovaara L, Aro K.

Eur Arch Otorhinolaryngol. 2017 Nov;274(11):3977-3983. doi: 10.1007/s00405-017-4728-z. Epub 2017 Sep 2.

39.

Point-of-care fluorescence imaging predicts the presence of pathogenic bacteria in wounds: a clinical study.

Rennie MY, Lindvere-Teene L, Tapang K, Linden R.

J Wound Care. 2017 Aug 2;26(8):452-460. doi: 10.12968/jowc.2017.26.8.452.

PMID:
28795890
40.

Pharmacogenetic and Pharmacokinetic Dose Individualization of the Taxane Chemotherapeutic Drugs Paclitaxel and Docetaxel.

Andriguetti NB, Raymundo S, Antunes MV, Perassolo MS, Verza SG, Suyenaga ES, Linden R.

Curr Med Chem. 2017;24(33):3559-3582. doi: 10.2174/0929867324666170623093445. Review.

PMID:
28641556
41.

Determination of Adeno-associated Virus Rep DNA Binding Using Fluorescence Anisotropy.

Zarate-Perez F, Santosh V, Bardelli M, Agundez L, Linden RM, Henckaerts E, Escalante CR.

Bio Protoc. 2017 Mar 20;7(6). pii: e2194.

42.

Prognostic implications of occult nodal tumour cells in stage I and II colon cancer: The correlation between micrometastasis and disease recurrence.

Sloothaak DAM, van der Linden RLA, van de Velde CJH, Bemelman WA, Lips DJ, van der Linden JC, Doornewaard H, Tanis PJ, Bosscha K, van der Zaag ES, Buskens CJ.

Eur J Surg Oncol. 2017 Aug;43(8):1456-1462. doi: 10.1016/j.ejso.2017.04.012. Epub 2017 May 5.

PMID:
28576463
43.

Suicide attempt with acetonitrile ingestion in a nursing mother.

De Capitani EM, Borrasca-Fernandes CF, Branco Pimenta M, Prado CC, Soubhia PC, Lanaro R, Mello Moreira S, Linden R, Nóbrega HV, Bucaretchi F, Costa JL.

Clin Toxicol (Phila). 2017 Sep;55(8):929-933. doi: 10.1080/15563650.2017.1324977. Epub 2017 May 11.

PMID:
28494173
44.

The Biological Function of the Prion Protein: A Cell Surface Scaffold of Signaling Modules.

Linden R.

Front Mol Neurosci. 2017 Mar 20;10:77. doi: 10.3389/fnmol.2017.00077. eCollection 2017.

45.

Improved detection of clinically relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers.

Ottolino-Perry K, Chamma E, Blackmore KM, Lindvere-Teene L, Starr D, Tapang K, Rosen CF, Pitcher B, Panzarella T, Linden R, DaCosta RS.

Int Wound J. 2017 Oct;14(5):833-841. doi: 10.1111/iwj.12717. Epub 2017 Feb 28.

PMID:
28244218
46.

Determination of topiramate in dried blood spots using single-quadrupole gas chromatography-mass spectrometry after flash methylation with trimethylanilinium hydroxide.

Hahn RZ, Antunes MV, Costa Arnhold P, Andriguetti NB, Verza SG, Linden R.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 1;1046:131-137. doi: 10.1016/j.jchromb.2017.01.047. Epub 2017 Feb 1.

PMID:
28178597
47.

rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia.

Cabral-Miranda F, Nicoloso-Simões E, Adão-Novaes J, Chiodo V, Hauswirth WW, Linden R, Chiarini LB, Petrs-Silva H.

Mol Ther. 2017 Feb 1;25(2):392-400. doi: 10.1016/j.ymthe.2016.11.017. Epub 2016 Dec 31.

48.

Richness, coverage and concentration of heavy metals in vascular epiphytes along an urbanization gradient.

Becker DFP, Linden R, Schmitt JL.

Sci Total Environ. 2017 Apr 15;584-585:48-54. doi: 10.1016/j.scitotenv.2017.01.092. Epub 2017 Jan 27.

PMID:
28135612
49.

Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication.

Seyffert M, Glauser DL, Schraner EM, de Oliveira AP, Mansilla-Soto J, Vogt B, Büning H, Linden RM, Ackermann M, Fraefel C.

PLoS One. 2017 Jan 26;12(1):e0170908. doi: 10.1371/journal.pone.0170908. eCollection 2017.

50.

Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice.

Fuijkschot WW, Morrison MC, van der Linden R, Krijnen PAJ, Zethof IPA, Theyse LFH, Kleemann R, Niessen HWM, Smulders YM.

Atherosclerosis. 2016 Dec;255:164-170. doi: 10.1016/j.atherosclerosis.2016.07.909. Epub 2016 Oct 28.

PMID:
27825629

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