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Physiological signaling in the absence of amidated peptides.

Lindberg I, Glembotski CC.

Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19774-19776. doi: 10.1073/pnas.1914001116. Epub 2019 Sep 12. No abstract available.


Reduced Stability and pH-Dependent Activity of a Common Obesity-Linked PCSK1 Polymorphism, N221D.

Jarvela TS, Shakya M, Bachor T, White A, Low MJ, Lindberg I.

Endocrinology. 2019 Nov 1;160(11):2630-2645. doi: 10.1210/en.2019-00418.


"Struggling to settle with a damaged body" - A Swedish qualitative study of women's experiences one year after obstetric anal sphincter muscle injury (OASIS) at childbirth.

Lindqvist M, Lindberg I, Nilsson M, Uustal E, Persson M.

Sex Reprod Healthc. 2019 Mar;19:36-41. doi: 10.1016/j.srhc.2018.11.002. Epub 2018 Nov 20.


Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.

Van Lam van T, Ivanova T, Hardes K, Heindl MR, Morty RE, Böttcher-Friebertshäuser E, Lindberg I, Than ME, Dahms SO, Steinmetzer T.

ChemMedChem. 2019 Mar 22;14(6):673-685. doi: 10.1002/cmdc.201800807. Epub 2019 Feb 20.


The Swedish version of the Normalization Process Theory Measure S-NoMAD: translation, adaptation, and pilot testing.

Elf M, Nordmark S, Lyhagen J, Lindberg I, Finch T, Åberg AC.

Implement Sci. 2018 Dec 4;13(1):146. doi: 10.1186/s13012-018-0835-5.


7B2 chaperone knockout in APP model mice results in reduced plaque burden.

Jarvela TS, Womack T, Georgiou P, Gould TD, Eriksen JL, Lindberg I.

Sci Rep. 2018 Jun 28;8(1):9813. doi: 10.1038/s41598-018-28031-7.


'A worse nightmare than expected' - a Swedish qualitative study of women's experiences two months after obstetric anal sphincter muscle injury.

Lindqvist M, Persson M, Nilsson M, Uustal E, Lindberg I.

Midwifery. 2018 Jun;61:22-28. doi: 10.1016/j.midw.2018.02.015. Epub 2018 Feb 20.


Patients' and Healthcare Personnel's Experiences of Health Coaching with Online Self-Management in the Renewing Health Project.

Lindberg I, Lindberg B, Söderberg S.

Int J Telemed Appl. 2017;2017:9306192. doi: 10.1155/2017/9306192. Epub 2017 Dec 31.


Surgery for Drug-Resistant Epilepsy in Children.

Rydenhag B, Lindberg IO, Malmgren K.

N Engl J Med. 2018 Jan 25;378(4):398. doi: 10.1056/NEJMc1715424. No abstract available.


Optimization of Substrate-Analogue Furin Inhibitors.

Ivanova T, Hardes K, Kallis S, Dahms SO, Than ME, Künzel S, Böttcher-Friebertshäuser E, Lindberg I, Jiao GS, Bartenschlager R, Steinmetzer T.

ChemMedChem. 2017 Dec 7;12(23):1953-1968. doi: 10.1002/cmdc.201700596. Epub 2017 Nov 16.


Cross-seeding of prions by aggregated α-synuclein leads to transmissible spongiform encephalopathy.

Katorcha E, Makarava N, Lee YJ, Lindberg I, Monteiro MJ, Kovacs GG, Baskakov IV.

PLoS Pathog. 2017 Aug 10;13(8):e1006563. doi: 10.1371/journal.ppat.1006563. eCollection 2017 Aug.


Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population.

Winters A, Ramos-Molina B, Jarvela TS, Yerges-Armstrong L, Pollin TI, Lindberg I.

Diabetes Res Clin Pract. 2017 Sep;131:82-90. doi: 10.1016/j.diabres.2017.06.023. Epub 2017 Jul 3.


Telemonitoring and Health Counseling for Self-Management Support of Patients With Type 2 Diabetes: A Randomized Controlled Trial.

Lindberg I, Torbjørnsen A, Söderberg S, Ribu L.

JMIR Diabetes. 2017 Jun 26;2(1):e10. doi: 10.2196/diabetes.6884.


Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin.

Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T.

ChemMedChem. 2017 Apr 20;12(8):613-620. doi: 10.1002/cmdc.201700108. Epub 2017 Apr 4.


Going from "paper and pen" to ICT systems: Perspectives on managing the change process.

Andersson Marchesoni M, Axelsson K, Fältholm Y, Lindberg I.

Inform Health Soc Care. 2017 Mar;42(2):109-121. doi: 10.3109/17538157.2015.1033526. Epub 2016 Oct 7.


Healthcare personnel's experiences using video consultation in primary healthcare in rural areas.

Johansson AM, Lindberg I, Söderberg S.

Prim Health Care Res Dev. 2017 Jan;18(1):73-83. Epub 2016 Sep 19.


The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity.

Jarvela TS, Lam HA, Helwig M, Lorenzen N, Otzen DE, McLean PJ, Maidment NT, Lindberg I.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4708-15. doi: 10.1073/pnas.1601091113. Epub 2016 Jul 25.


PCSK1 Variants and Human Obesity.

Ramos-Molina B, Martin MG, Lindberg I.

Prog Mol Biol Transl Sci. 2016;140:47-74. doi: 10.1016/bs.pmbts.2015.12.001. Epub 2016 Jan 29. Review.


Process evaluation of discharge planning implementation in healthcare using normalization process theory.

Nordmark S, Zingmark K, Lindberg I.

BMC Med Inform Decis Mak. 2016 Apr 27;16:48. doi: 10.1186/s12911-016-0285-4.


Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition.

Yamamoto H, Ramos-Molina B, Lick AN, Prideaux M, Albornoz V, Bonewald L, Lindberg I.

Bone. 2016 Mar;84:120-130. doi: 10.1016/j.bone.2015.12.055. Epub 2015 Dec 31.


Chaperones in Neurodegeneration.

Lindberg I, Shorter J, Wiseman RL, Chiti F, Dickey CA, McLean PJ.

J Neurosci. 2015 Oct 14;35(41):13853-9. doi: 10.1523/JNEUROSCI.2600-15.2015. Review.


Enabling sense-making for patients receiving outpatient palliative treatment: A participatory action research driven model for person-centered communication.

Öhlén J, Carlsson G, Jepsen A, Lindberg I, Friberg F.

Palliat Support Care. 2016 Jun;14(3):212-24. doi: 10.1017/S1478951515000814. Epub 2015 Aug 3.


Technologies in older people's care.

Andersson Marchesoni M, Axelsson K, Fältholm Y, Lindberg I.

Nurs Ethics. 2017 Mar;24(2):125-137. doi: 10.1177/0969733015594665. Epub 2016 Aug 3.


Revisiting PC1/3 Mutants: Dominant-Negative Effect of Endoplasmic Reticulum-Retained Mutants.

Blanco EH, Ramos-Molina B, Lindberg I.

Endocrinology. 2015 Oct;156(10):3625-37. doi: 10.1210/en.2015-1068. Epub 2015 Jul 24.


Cationic Cell-Penetrating Peptides Are Potent Furin Inhibitors.

Ramos-Molina B, Lick AN, Nasrolahi Shirazi A, Oh D, Tiwari R, El-Sayed NS, Parang K, Lindberg I.

PLoS One. 2015 Jun 25;10(6):e0130417. doi: 10.1371/journal.pone.0130417. eCollection 2015.


Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays.

Ramos-Molina B, Lick AN, Blanco EH, Posada-Salgado JA, Martinez-Mayorga K, Johnson AT, Jiao GS, Lindberg I.

Biochem Pharmacol. 2015 Jul 15;96(2):107-18. doi: 10.1016/j.bcp.2015.05.008. Epub 2015 May 21.


Novel Furin Inhibitors with Potent Anti-infectious Activity.

Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T.

ChemMedChem. 2015 Jul;10(7):1218-31. doi: 10.1002/cmdc.201500103. Epub 2015 May 14.


Phosphorylation and Alternative Splicing of 7B2 Reduce Prohormone Convertase 2 Activation.

Ramos-Molina B, Lindberg I.

Mol Endocrinol. 2015 May;29(5):756-64. doi: 10.1210/me.2014-1394. Epub 2015 Mar 26.


A novel familial mutation in the PCSK1 gene that alters the oxyanion hole residue of proprotein convertase 1/3 and impairs its enzymatic activity.

Wilschanski M, Abbasi M, Blanco E, Lindberg I, Yourshaw M, Zangen D, Berger I, Shteyer E, Pappo O, Bar-Oz B, Martín MG, Elpeleg O.

PLoS One. 2014 Oct 1;9(10):e108878. doi: 10.1371/journal.pone.0108878. eCollection 2014.


Patients' Experiences with Specialist Care via Video Consultation in Primary Healthcare in Rural Areas.

Johansson AM, Lindberg I, Söderberg S.

Int J Telemed Appl. 2014;2014:143824. doi: 10.1155/2014/143824. Epub 2014 Aug 24.


FGF23 is endogenously phosphorylated in bone cells.

Lindberg I, Pang HW, Stains JP, Clark D, Yang AJ, Bonewald L, Li KZ.

J Bone Miner Res. 2015 Mar;30(3):449-54. doi: 10.1002/jbmr.2354.


Digital support for medication administration--a means for reaching the goal of providing good care?

Marchesoni MA, Axelsson K, Lindberg I.

J Health Organ Manag. 2014;28(3):327-43.


Biochemical and cell biological properties of the human prohormone convertase 1/3 Ser357Gly mutation: a PC1/3 hypermorph.

Blanco EH, Peinado JR, Martín MG, Lindberg I.

Endocrinology. 2014 Sep;155(9):3434-47. doi: 10.1210/en.2013-2151. Epub 2014 Jun 16.


Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells.

Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2319-28. doi: 10.1073/pnas.1323066111. Epub 2014 May 19.


Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function.

Prabhu Y, Blanco EH, Liu M, Peinado JR, Wheeler MC, Gekakis N, Arvan P, Lindberg I.

Endocrinology. 2014 Jul;155(7):2391-401. doi: 10.1210/en.2013-1985. Epub 2014 May 14.


Views of residents of rural areas on accessibility to specialist care through videoconference.

Johansson AM, Söderberg S, Lindberg I.

Technol Health Care. 2014;22(1):147-55. doi: 10.3233/THC-140776.


Exome sequencing finds a novel PCSK1 mutation in a child with generalized malabsorptive diarrhea and diabetes insipidus.

Yourshaw M, Solorzano-Vargas RS, Pickett LA, Lindberg I, Wang J, Cortina G, Pawlikowska-Haddal A, Baron H, Venick RS, Nelson SF, Martín MG.

J Pediatr Gastroenterol Nutr. 2013 Dec;57(6):759-67. doi: 10.1097/MPG.0b013e3182a8ae6c.


A qualitative study of new fathers' experiences of care in relation to complicated childbirth.

Lindberg I, Engström A.

Sex Reprod Healthc. 2013 Dec;4(4):147-52. doi: 10.1016/j.srhc.2013.10.002. Epub 2013 Oct 12.


A novel function for proSAAS as an amyloid anti-aggregant in Alzheimer's disease.

Hoshino A, Helwig M, Rezaei S, Berridge C, Eriksen JL, Lindberg I.

J Neurochem. 2014 Feb;128(3):419-30. doi: 10.1111/jnc.12454. Epub 2013 Oct 24.


Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS.

Peinado JR, Sami F, Rajpurohit N, Lindberg I.

FEBS Lett. 2013 Nov 1;587(21):3406-11. doi: 10.1016/j.febslet.2013.09.006. Epub 2013 Sep 13.


Critical care nurses' experiences of nursing mothers in an ICU after complicated childbirth.

Engström A, Lindberg I.

Nurs Crit Care. 2013 Sep;18(5):251-7. doi: 10.1111/nicc.12027. Epub 2013 Jul 8.


Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathies in a pediatric cohort.

Martín MG, Lindberg I, Solorzano-Vargas RS, Wang J, Avitzur Y, Bandsma R, Sokollik C, Lawrence S, Pickett LA, Chen Z, Egritas O, Dalgic B, Albornoz V, de Ridder L, Hulst J, Gok F, Aydoğan A, Al-Hussaini A, Gok DE, Yourshaw M, Wu SV, Cortina G, Stanford S, Georgia S.

Gastroenterology. 2013 Jul;145(1):138-148. doi: 10.1053/j.gastro.2013.03.048. Epub 2013 Apr 2.


Identification of a small molecule that selectively inhibits mouse PC2 over mouse PC1/3: a computational and experimental study.

Yongye AB, Vivoli M, Lindberg I, Appel JR, Houghten RA, Martinez-Mayorga K.

PLoS One. 2013;8(2):e56957. doi: 10.1371/journal.pone.0056957. Epub 2013 Feb 22.


The views of health-care personnel about video consultation prior to implementation in primary health care in rural areas.

Johansson AM, Lindberg I, Söderberg S.

Prim Health Care Res Dev. 2014 Apr;15(2):170-9. doi: 10.1017/S1463423613000030. Epub 2013 Feb 12.


Functional consequences of a novel variant of PCSK1.

Pickett LA, Yourshaw M, Albornoz V, Chen Z, Solorzano-Vargas RS, Nelson SF, Martín MG, Lindberg I.

PLoS One. 2013;8(1):e55065. doi: 10.1371/journal.pone.0055065. Epub 2013 Jan 28.


The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins.

Helwig M, Hoshino A, Berridge C, Lee SN, Lorenzen N, Otzen DE, Eriksen JL, Lindberg I.

J Biol Chem. 2013 Jan 11;288(2):1114-24. doi: 10.1074/jbc.M112.417071. Epub 2012 Nov 21.


Why do smokers diagnosed with COPD not quit smoking? - a qualitative study.

Eklund BM, Nilsson S, Hedman L, Lindberg I.

Tob Induc Dis. 2012 Oct 22;10(1):17. doi: 10.1186/1617-9625-10-17.


The neuroendocrine protein 7B2 is intrinsically disordered.

Dasgupta I, Sanglas L, Enghild JJ, Lindberg I.

Biochemistry. 2012 Sep 25;51(38):7456-64. doi: 10.1021/bi300871k. Epub 2012 Sep 14.


Generation and characterization of non-competitive furin-inhibiting nanobodies.

Zhu J, Declercq J, Roucourt B, Ghassabeh GH, Meulemans S, Kinne J, David G, Vermorken AJ, Van de Ven WJ, Lindberg I, Muyldermans S, Creemers JW.

Biochem J. 2012 Nov 15;448(1):73-82. doi: 10.1042/BJ20120537.


Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype.

Yuan B, Feng JQ, Bowman S, Liu Y, Blank RD, Lindberg I, Drezner MK.

J Bone Miner Res. 2013 Jan;28(1):56-72. doi: 10.1002/jbmr.1738. Erratum in: J Bone Miner Res. 2013 Aug;28(8):1855.

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