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Items: 16


Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation.

Stock CJW, Michaeloudes C, Leoni P, Durham AL, Mumby S, Wells AU, Chung KF, Adcock IM, Renzoni EA, Lindahl GE.

Biomed Res Int. 2019 Apr 18;2019:1484736. doi: 10.1155/2019/1484736. eCollection 2019.


Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease.

Lindahl GE, Stock CJ, Shi-Wen X, Leoni P, Sestini P, Howat SL, Bou-Gharios G, Nicholson AG, Denton CP, Grutters JC, Maher TM, Wells AU, Abraham DJ, Renzoni EA.

Respir Res. 2013 Aug 2;14:80. doi: 10.1186/1465-9921-14-80.


Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis.

Stock CJ, Sato H, Fonseca C, Banya WA, Molyneaux PL, Adamali H, Russell AM, Denton CP, Abraham DJ, Hansell DM, Nicholson AG, Maher TM, Wells AU, Lindahl GE, Renzoni EA.

Thorax. 2013 May;68(5):436-41. doi: 10.1136/thoraxjnl-2012-201786. Epub 2013 Jan 15.


Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen.

Ponticos M, Holmes AM, Shi-wen X, Leoni P, Khan K, Rajkumar VS, Hoyles RK, Bou-Gharios G, Black CM, Denton CP, Abraham DJ, Leask A, Lindahl GE.

Arthritis Rheum. 2009 Jul;60(7):2142-55. doi: 10.1002/art.24620.


Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model.

Hoyles RK, Khan K, Shiwen X, Howat SL, Lindahl GE, Leoni P, du Bois RM, Wells AU, Black CM, Abraham DJ, Denton CP.

Arthritis Rheum. 2008 Apr;58(4):1175-88. doi: 10.1002/art.23379. Erratum in: Arthritis Rheum. 2015 Oct;67(10):2741.


The effect of mechanical strain on protease production by keratinocytes.

Bhadal N, Wall IB, Porter SR, Broad S, Lindahl GE, Whawell S, Lewis MP.

Br J Dermatol. 2008 Feb;158(2):396-8. Epub 2007 Dec 7.


A polymorphism in the CTGF promoter region associated with systemic sclerosis.

Fonseca C, Lindahl GE, Ponticos M, Sestini P, Renzoni EA, Holmes AM, Spagnolo P, Pantelidis P, Leoni P, McHugh N, Stock CJ, Shi-Wen X, Denton CP, Black CM, Welsh KI, du Bois RM, Abraham DJ.

N Engl J Med. 2007 Sep 20;357(12):1210-20.


Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k).

Denton CP, Lindahl GE, Khan K, Shiwen X, Ong VH, Gaspar NJ, Lazaridis K, Edwards DR, Leask A, Eastwood M, Leoni P, Renzoni EA, Bou Gharios G, Abraham DJ, Black CM.

J Biol Chem. 2005 Apr 22;280(16):16053-65. Epub 2005 Feb 11.


The Y-box binding protein YB-1 suppresses collagen alpha 1(I) gene transcription via an evolutionarily conserved regulatory element in the proximal promoter.

Norman JT, Lindahl GE, Shakib K, En-Nia A, Yilmaz E, Mertens PR.

J Biol Chem. 2001 Aug 10;276(32):29880-90. Epub 2001 Jun 6.


The recurring evolution of lipoprotein(a). Insights from cloning of hedgehog apolipoprotein(a).

Lawn RM, Boonmark NW, Schwartz K, Lindahl GE, Wade DP, Byrne CD, Fong KJ, Meer K, Patthy L.

J Biol Chem. 1995 Oct 13;270(41):24004-9.


C/T polymorphism in the 5' untranslated region of the apolipoprotein(a) gene introduces an upstream ATG and reduces in vitro translation.

Zysow BR, Lindahl GE, Wade DP, Knight BL, Lawn RM.

Arterioscler Thromb Vasc Biol. 1995 Jan;15(1):58-64.


Genetic influences on lipoprotein(a) concentration.

Wade DP, Clarke JG, Lindahl GE, Liu AC, Zysow BR, Meer K, Schwartz K, Lawn RM.

Biochem Soc Trans. 1993 May;21(2):499-502. Review. No abstract available.


5' control regions of the apolipoprotein(a) gene and members of the related plasminogen gene family.

Wade DP, Clarke JG, Lindahl GE, Liu AC, Zysow BR, Meer K, Schwartz K, Lawn RM.

Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1369-73.

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