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Items: 1 to 50 of 57

1.

Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons.

Shi Y, Hung ST, Rocha G, Lin S, Linares GR, Staats KA, Seah C, Wang Y, Chickering M, Lai J, Sugawara T, Sagare AP, Zlokovic BV, Ichida JK.

JCI Insight. 2019 Jul 16;5. pii: 127736. doi: 10.1172/jci.insight.127736.

2.

Transplantation of Mesenchymal Stem Cells Overexpressing FGF21 Facilitates Cognitive Recovery and Enhances Neurogenesis in a Mouse Model of Traumatic Brain Injury.

Shahror RA, Linares G, Wang Y, Hsueh SC, Wu CC, Chuang DM, Chiang YH, Chen KY.

J Neurotrauma. 2019 Jul 12. doi: 10.1089/neu.2019.6422. [Epub ahead of print]

PMID:
31298621
3.

Toxicity of blue led light and A2E is associated to mitochondrial dynamics impairment in ARPE-19 cells: implications for age-related macular degeneration.

Alaimo A, Liñares GG, Bujjamer JM, Gorojod RM, Alcon SP, Martínez JH, Baldessari A, Grecco HE, Kotler ML.

Arch Toxicol. 2019 May;93(5):1401-1415. doi: 10.1007/s00204-019-02409-6. Epub 2019 Feb 18.

PMID:
30778631
4.

Phenotypic ASCOD characterisations of ischaemic stroke in the young at an urban tertiary care centre.

Liu A, Pirastehfar M, Yu D, Linares G.

Stroke Vasc Neurol. 2018 Jul 30;3(4):209-214. doi: 10.1136/svn-2017-000139. eCollection 2018 Dec.

5.

Gluten-Free Snacks Based on Brown Rice and Amaranth Flour with Incorporation of Cactus Pear Peel Powder: Physical, Nutritional, and Sensorial Properties.

Miranda DV, Rojas ML, Pagador S, Lescano L, Sanchez-Gonzalez J, Linares G.

Int J Food Sci. 2018 Oct 29;2018:7120327. doi: 10.1155/2018/7120327. eCollection 2018.

6.

Chemoenzymatic Synthesis of Nitrogen Polymers with Biomedical Applications Catalyzed by Lipases.

Baldessari A, Liñares GG.

Methods Mol Biol. 2018;1835:359-376. doi: 10.1007/978-1-4939-8672-9_20.

PMID:
30109663
7.

The disappointing contribution of anti-human leukocyte antigen donor-specific antibodies characteristics for predicting allograft loss.

Courant M, Visentin J, Linares G, Dubois V, Lepreux S, Guidicelli G, Thaunat O, Merville P, Couzi L, Taupin JL.

Nephrol Dial Transplant. 2018 Oct 1;33(10):1872. doi: 10.1093/ndt/gfy182. No abstract available.

PMID:
29897514
8.

The disappointing contribution of anti-human leukocyte antigen donor-specific antibodies characteristics for predicting allograft loss.

Courant M, Visentin J, Linares G, Dubois V, Lepreux S, Guidicelli G, Thaunat O, Merville P, Couzi L, Taupin JL.

Nephrol Dial Transplant. 2018 Oct 1;33(10):1853-1863. doi: 10.1093/ndt/gfy088. Erratum in: Nephrol Dial Transplant. 2018 Oct 1;33(10):1872.

PMID:
29672702
9.

Chemoenzymatic synthesis of new derivatives of glycyrrhetinic acid with antiviral activity. Molecular docking study.

Zígolo MA, Salinas M, Alché L, Baldessari A, Liñares GG.

Bioorg Chem. 2018 Aug;78:210-219. doi: 10.1016/j.bioorg.2018.03.018. Epub 2018 Mar 19.

PMID:
29602045
10.

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.

Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK.

Nat Med. 2018 Mar;24(3):313-325. doi: 10.1038/nm.4490. Epub 2018 Feb 5.

11.

Impact of pre-drying and frying time on physical properties and sensorial acceptability of fried potato chips.

Cruz G, Cruz-Tirado JP, Delgado K, Guzman Y, Castro F, Rojas ML, Linares G.

J Food Sci Technol. 2018 Jan;55(1):138-144. doi: 10.1007/s13197-017-2866-3. Epub 2017 Dec 16.

12.

Tumor-Associated Macrophages Can Contribute to Antitumor Activity through FcγR-Mediated Processing of Antibody-Drug Conjugates.

Li F, Ulrich M, Jonas M, Stone IJ, Linares G, Zhang X, Westendorf L, Benjamin DR, Law CL.

Mol Cancer Ther. 2017 Jul;16(7):1347-1354. doi: 10.1158/1535-7163.MCT-17-0019. Epub 2017 Mar 24.

13.

Drug therapy management in a pharmacist-run stroke prevention clinic.

Andres J, Ruchalski C, Katz P, Linares G.

Am J Health Syst Pharm. 2016 Sep 15;73(18):1388-90. doi: 10.2146/ajhp150773. No abstract available.

PMID:
27605317
14.

Lung intragraft donor-specific antibodies as a risk factor for graft loss.

Visentin J, Chartier A, Massara L, Linares G, Guidicelli G, Blanchard E, Parrens M, Begueret H, Dromer C, Taupin JL.

J Heart Lung Transplant. 2016 Dec;35(12):1418-1426. doi: 10.1016/j.healun.2016.06.010. Epub 2016 Jun 24.

PMID:
27450460
15.

Preconditioning mesenchymal stem cells with the mood stabilizers lithium and valproic acid enhances therapeutic efficacy in a mouse model of Huntington's disease.

Linares GR, Chiu CT, Scheuing L, Leng Y, Liao HM, Maric D, Chuang DM.

Exp Neurol. 2016 Jul;281:81-92. doi: 10.1016/j.expneurol.2016.04.003. Epub 2016 Apr 13.

PMID:
27085395
16.

The future of endovascular treatment: Insights from the ESCAPE investigators.

Klourfeld E, Zerna C, Al-Ajlan FS, Kamal N, Randhawa P, Yu AY, Dowlatshahi D, Thornton J, Williams D, Holmstedt C, Kelly M, Frei D, Baxter B, Linares G, Bang OY, Poppe AY, Montanera W, Rempel J, Eesa M, Menon BK, Demchuk AM, Goyal M, Hill MD; ESCAPE Trial Investigators.

Int J Stroke. 2016 Feb;11(2):156-63. doi: 10.1177/1747493015622962.

PMID:
26783306
17.

New cholic acid derivatives: Biocatalytic synthesis and molecular docking study.

Zígolo MA, Liñares GG, Baldessari A.

Steroids. 2016 Mar;107:10-9. doi: 10.1016/j.steroids.2015.12.014. Epub 2015 Dec 21.

PMID:
26718086
18.

Randomized assessment of rapid endovascular treatment of ischemic stroke.

Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, Roy D, Jovin TG, Willinsky RA, Sapkota BL, Dowlatshahi D, Frei DF, Kamal NR, Montanera WJ, Poppe AY, Ryckborst KJ, Silver FL, Shuaib A, Tampieri D, Williams D, Bang OY, Baxter BW, Burns PA, Choe H, Heo JH, Holmstedt CA, Jankowitz B, Kelly M, Linares G, Mandzia JL, Shankar J, Sohn SI, Swartz RH, Barber PA, Coutts SB, Smith EE, Morrish WF, Weill A, Subramaniam S, Mitha AP, Wong JH, Lowerison MW, Sajobi TT, Hill MD; ESCAPE Trial Investigators.

N Engl J Med. 2015 Mar 12;372(11):1019-30. doi: 10.1056/NEJMoa1414905. Epub 2015 Feb 11.

19.

The mood stabilizer lithium potentiates the antidepressant-like effects and ameliorates oxidative stress induced by acute ketamine in a mouse model of stress.

Chiu CT, Scheuing L, Liu G, Liao HM, Linares GR, Lin D, Chuang DM.

Int J Neuropsychopharmacol. 2014 Dec 28;18(6). pii: pyu102. doi: 10.1093/ijnp/pyu102.

20.

Preclinical and clinical investigations of mood stabilizers for Huntington's disease: what have we learned?

Scheuing L, Chiu CT, Liao HM, Linares GR, Chuang DM.

Int J Biol Sci. 2014 Sep 10;10(9):1024-38. doi: 10.7150/ijbs.9898. eCollection 2014. Review.

21.

[Effects of education and strength training on functional tests among older people with osteoarthritis].

Jiménez S CE, Fernández G R, Zurita O F, Linares G D, Farías M A.

Rev Med Chil. 2014 Apr;142(4):436-42. doi: 10.4067/S0034-98872014000400004. Spanish.

22.

Acute cervical myelopathy due to presumed fibrocartilaginous embolism: a case report and systematic review of the literature.

Cuello JP, Ortega-Gutierrez S, Linares G, Agarwal S, Cunningham A, Mohr JP, Mayer SA, Marshall RS, Claassen J, Badjatia N, Elkind MS, Lee K.

J Spinal Disord Tech. 2014 Dec;27(8):E276-81. doi: 10.1097/BSD.0000000000000115. Review.

PMID:
24901879
23.

A new avenue for lithium: intervention in traumatic brain injury.

Leeds PR, Yu F, Wang Z, Chiu CT, Zhang Y, Leng Y, Linares GR, Chuang DM.

ACS Chem Neurosci. 2014 Jun 18;5(6):422-33. doi: 10.1021/cn500040g. Epub 2014 Apr 11. Review.

24.

Primary manual aspiration thrombectomy (MAT) for acute ischemic stroke: safety, feasibility and outcomes in 112 consecutive patients.

Jankowitz B, Grandhi R, Horev A, Aghaebrahim A, Jadhav A, Linares G, Jovin T.

J Neurointerv Surg. 2015 Jan;7(1):27-31. doi: 10.1136/neurintsurg-2013-011024. Epub 2014 Jan 2.

PMID:
24385557
25.

Transcervical access in acute ischemic stroke.

Jadhav AP, Ribo M, Grandhi R, Linares G, Aghaebrahim A, Jovin TG, Jankowitz BT.

J Neurointerv Surg. 2014 Nov;6(9):652-7. doi: 10.1136/neurintsurg-2013-010971. Epub 2013 Nov 7.

PMID:
24203916
26.

Onyx embolization of infectious intracranial aneurysms.

Grandhi R, Zwagerman NT, Linares G, Monaco EA 3rd, Jovin T, Horowitz M, Jankowitz BT.

J Neurointerv Surg. 2014 Jun;6(5):353-6. doi: 10.1136/neurintsurg-2013-010755. Epub 2013 May 4.

PMID:
23645573
27.

Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation.

Linares GR, Brommage R, Powell DR, Xing W, Chen ST, Alshbool FZ, Lau KH, Wergedal JE, Mohan S.

J Bone Miner Res. 2012 Jul;27(7):1553-65. doi: 10.1002/jbmr.1600.

28.

Too good to treat? Outcomes in patients not receiving thrombolysis due to mild deficits or rapidly improving symptoms.

Willey JZ, Stillman J, Rivolta JA, Vieira J, Doyle MM, Linares G, Marchidann A, Elkind MS, Boden-Albala B, Marshall RS.

Int J Stroke. 2012 Apr;7(3):202-6. doi: 10.1111/j.1747-4949.2011.00696.x. Epub 2011 Nov 22.

29.

Role of diabetes- and obesity-related protein in the regulation of osteoblast differentiation.

Linares GR, Xing W, Burghardt H, Baumgartner B, Chen ST, Ricart W, Fernández-Real JM, Zorzano A, Mohan S.

Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E40-8. doi: 10.1152/ajpendo.00065.2011. Epub 2011 Apr 5.

30.

Can a simple blood test quantify brain injury?

Mayer SA, Linares G.

Crit Care. 2009;13(4):166. doi: 10.1186/cc7929. Epub 2009 Jul 15.

31.

Hypothermia for the treatment of ischemic and hemorrhagic stroke.

Linares G, Mayer SA.

Crit Care Med. 2009 Jul;37(7 Suppl):S243-9. doi: 10.1097/CCM.0b013e3181aa5de1. Review.

PMID:
19535954
32.

Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress.

Linares GR, Xing W, Govoni KE, Chen ST, Mohan S.

Bone. 2009 May;44(5):795-804. doi: 10.1016/j.bone.2009.01.003. Epub 2009 Jan 14.

33.

T-box 3 negatively regulates osteoblast differentiation by inhibiting expression of osterix and runx2.

Govoni KE, Linares GR, Chen ST, Pourteymoor S, Mohan S.

J Cell Biochem. 2009 Feb 15;106(3):482-90. doi: 10.1002/jcb.22035.

34.

Fluorine-containing aryloxyethyl thiocyanate derivatives are potent inhibitors of Trypanosoma cruzi and Toxoplasma gondii proliferation.

Liñares GG, Gismondi S, Codesido NO, Moreno SN, Docampo R, Rodriguez JB.

Bioorg Med Chem Lett. 2007 Sep 15;17(18):5068-71. Epub 2007 Jul 13.

35.

Current status and progresses made in malaria chemotherapy.

Liñares GE, Rodriguez JB.

Curr Med Chem. 2007;14(3):289-314. Review.

PMID:
17305534
36.

Progresses in the field of drug design to combat tropical protozoan parasitic diseases.

Liñares GE, Ravaschino EL, Rodriguez JB.

Curr Med Chem. 2006;13(3):335-60. Review.

PMID:
16475941
37.

Clinical pharmacokinetics of toremifene.

Taras TL, Wurz GT, Linares GR, DeGregorio MW.

Clin Pharmacokinet. 2000 Nov;39(5):327-34. Review.

PMID:
11108432
38.

Diurnal variations of opioid peptides and synenkephalin in vitro release in the amygdala of kindled rats.

Asai M, Zubieta M, Matamoros-Trejo G, Linares G, Agustín P.

Neuropeptides. 1998 Jun;32(3):293-9.

PMID:
10189066
39.

Low-grade MALT lymphoma mimicking Waldenström's macroglobulinemia.

Allez M, Mariette X, Linares G, Bertheau P, Jian R, Brouet JC.

Leukemia. 1999 Mar;13(3):484-5. No abstract available.

PMID:
10086741
40.

Long-term pharmacological kindling increases in vitro release of IR-Met and IR-Leu-enkephalin from amygdala.

Asai M, Matamoros-Trejo G, Linares G.

Comp Biochem Physiol A Mol Integr Physiol. 1998 Jun;120(2):269-75.

PMID:
9773507
41.

EGF modulation of the ras-related rhoB gene expression in human breast-cancer cell lines.

de Cremoux P, Gauville C, Closson V, Linares G, Calvo F, Tavitian A, Olofsson B.

Int J Cancer. 1994 Nov 1;59(3):408-15.

PMID:
7927950
42.

p53 mutations and overexpression in locally advanced breast cancers.

Faille A, De Cremoux P, Extra JM, Linares G, Espie M, Bourstyn E, De Rocquancourt A, Giacchetti S, Marty M, Calvo F.

Br J Cancer. 1994 Jun;69(6):1145-50.

43.

Cytogenetic characterization of a new human papillary thyroid carcinoma permanent cell line (GLAG-66).

Antonini P, Linares G, Gaillard N, Venuat AM, Schlumberger M, Travagli JP, Caillou B, Berger R, Parmentier C.

Cancer Genet Cytogenet. 1993 Jun;67(2):117-22.

PMID:
8330267
44.

Cytogenetic abnormalities in thyroid adenomas.

Antonini P, Vénuat AM, Linares G, Caillou B, Schlumberger M, Travagli JP, Berger R, Parmentier C.

Cancer Genet Cytogenet. 1991 Apr;52(2):157-64.

PMID:
2021917
45.

[The in vivo effect of the local administration of progesterone on the mitotic activity of human ductal breast tissue. Results of a pilot study].

Barrat J, de Lignières B, Marpeau L, Larue L, Fournier S, Nahoul K, Linares G, Giorgi H, Contesso G.

J Gynecol Obstet Biol Reprod (Paris). 1990;19(3):269-74. French.

PMID:
2345268
46.

A translocation (7;10)(q35;q21) in a differentiated papillary carcinoma of the thyroid.

Antonini P, Venuat AM, Linares G, Caillou B, Berger R, Parmentier C.

Cancer Genet Cytogenet. 1989 Aug;41(1):139-44.

PMID:
2766248
47.

Pentylenetetrazol-induced seizures produce an increased release of IR-Met-enkephalin from rat striatum in vitro.

Zubieta M, Vindrola O, Talavera E, Asai M, Massarini A, Linares G.

Brain Res. 1985 Dec 23;360(1-2):101-7.

PMID:
4075166
48.
49.

Pentylenetetrazol kindling produces a long-lasting elevation of IR-Met-enkephalin but not IR-Leu-enkephalin in rat brain.

Vindrola O, Asai M, Zubieta M, Talavera E, Rodriguez E, Linares G.

Brain Res. 1984 Apr 9;297(1):121-5.

PMID:
6722531
50.

Brain content of immunoreactive [Leu5]enkephalin and [Met5]enkephalin after pentylenetetrazol-induced convulsions.

Vindrola O, Asai M, Zubieta M, Linares G.

Eur J Pharmacol. 1983 May 20;90(1):85-9.

PMID:
6873178

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