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Items: 1 to 50 of 108

1.

A survey of core replacements in indole-based HIV-1 attachment inhibitors.

Wang T, Wallace OB, Zhang Z, Fang H, Yang Z, Robinson BA, Spicer TP, Gong YF, Blair WS, Shi PY, Lin PF, Deshpande M, Meanwell NA, Kadow JF.

Bioorg Med Chem Lett. 2019 Jun 1;29(11):1423-1429. doi: 10.1016/j.bmcl.2019.03.018. Epub 2019 Mar 28.

PMID:
30940396
2.

Clinical, Neuroimaging, and Pathological Analyses of 13 Chinese Leigh Syndrome Patients with Mitochondrial DNA Mutations.

Yu XL, Yan CZ, Ji KQ, Lin PF, Xu XB, Dai TJ, Li W, Zhao YY.

Chin Med J (Engl). 2018 Nov 20;131(22):2705-2712. doi: 10.4103/0366-6999.245265.

3.

Discovery of the Human Immunodeficiency Virus Type 1 (HIV-1) Attachment Inhibitor Temsavir and Its Phosphonooxymethyl Prodrug Fostemsavir.

Wang T, Ueda Y, Zhang Z, Yin Z, Matiskella J, Pearce BC, Yang Z, Zheng M, Parker DD, Yamanaka GA, Gong YF, Ho HT, Colonno RJ, Langley DR, Lin PF, Meanwell NA, Kadow JF.

J Med Chem. 2018 Jul 26;61(14):6308-6327. doi: 10.1021/acs.jmedchem.8b00759. Epub 2018 Jul 13.

PMID:
29920093
4.

Brucella induces unfolded protein response and inflammatory response via GntR in alveolar macrophages.

Zhou D, Zhi FJ, Qi MZ, Bai FR, Zhang G, Li JM, Liu H, Chen HT, Lin PF, Tang KQ, Liu W, Jin YP, Wang AH.

Oncotarget. 2017 Dec 26;9(4):5184-5196. doi: 10.18632/oncotarget.23706. eCollection 2018 Jan 12.

5.

"Low-tech" simulation of corneal foreign body removal.

Gallagher K, Lin PF, Koukkoulli A, Puertas R, Okhravi N.

Can J Ophthalmol. 2016 Oct;51(5):386-389. doi: 10.1016/j.jcjo.2016.03.016. Epub 2016 Jun 23. No abstract available.

PMID:
27769332
6.

[Reaction Kinetics and Impacting Mechanism of Cr(Ⅵ) Removal in Fe0-PRB Systems].

Lu X, Li M, Tang CM, Xin J, Lin PF, Liu X.

Huan Jing Ke Xue. 2016 Sep 8;37(9):3473-3479. doi: 10.13227/j.hjkx.2016.09.028. Chinese.

PMID:
29964783
8.

Prevalence of mitochondrial DNA mutations in sporadic patients with nonsyndromic sensorineural hearing loss.

Jiang H, Chen J, Li Y, Lin PF, He JG, Yang BB.

Braz J Otorhinolaryngol. 2016 Jul-Aug;82(4):391-6. doi: 10.1016/j.bjorl.2015.06.006. Epub 2015 Nov 5.

9.

Silencing effect of lentiviral vectors encod-ing shRNA of Herp on endoplasmic reticulum stress and inflammatory responses in RAW 264.7 macrophages.

Chen FL, Li Q, Zhang JY, Lei LJ, Zhang Z, Mahmoud TN, Wang XG, Lin PF, Jin YP, Wang AH.

Genet Mol Res. 2015 Dec 21;14(4):17587-98. doi: 10.4238/2015.December.21.31.

10.

Inhibitors of HIV-1 attachment: The discovery and structure-activity relationships of tetrahydroisoquinolines as replacements for the piperazine benzamide in the 3-glyoxylyl 6-azaindole pharmacophore.

Swidorski JJ, Liu Z, Yin Z, Wang T, Carini DJ, Rahematpura S, Zheng M, Johnson K, Zhang S, Lin PF, Parker DD, Li W, Meanwell NA, Hamann LG, Regueiro-Ren A.

Bioorg Med Chem Lett. 2016 Jan 1;26(1):160-7. doi: 10.1016/j.bmcl.2015.11.009. Epub 2015 Nov 5.

PMID:
26584882
11.

Expression and localization of Luman/CREB3 in mouse embryos during the pre-implantation period.

Mahmoud TN, Lin PF, Chen FL, Zhou JH, Wang XG, Wang N, Li X, Jin YP.

Genet Mol Res. 2015 Oct 29;14(4):13595-602. doi: 10.4238/2015.October.28.20. Erratum in: Genet Mol Res. 2016;15(1). doi: 10.4238/gmr.150156091.

12.

Hydrostable and Nitryl/Methyl-Functionalized Metal-Organic Framework for Drug Delivery and Highly Selective CO2 Adsorption.

Ma DY, Li Z, Xiao JX, Deng R, Lin PF, Chen RQ, Liang YQ, Guo HF, Liu B, Liu JQ.

Inorg Chem. 2015 Jul 20;54(14):6719-26. doi: 10.1021/acs.inorgchem.5b00335. Epub 2015 Jul 6.

PMID:
26146847
13.

Construction and expression of lentiviral vectors encoding recombinant mouse CREBZF in NIH 3T3 cells.

Chen F, Lin PF, Li X, Sun J, Zhang Z, Du E, Wang A, Jin YP.

Plasmid. 2014 Nov;76:24-31. doi: 10.1016/j.plasmid.2014.08.004. Epub 2014 Sep 6.

PMID:
25195838
14.

[Health for all--the development of community health nursing and public health nursing from the perspective of education].

Lin PF.

Hu Li Za Zhi. 2014 Jun;61(3):14-20. doi: 10.6224/JN.61.3.14. Chinese.

PMID:
24899554
15.

Correlations between the signal complexity of cerebral and cardiac electrical activity: a multiscale entropy analysis.

Lin PF, Lo MT, Tsao J, Chang YC, Lin C, Ho YL.

PLoS One. 2014 Feb 3;9(2):e87798. doi: 10.1371/journal.pone.0087798. eCollection 2014.

17.

Liposarcoma of the retropharyngeal space with rapidly worsening dyspnea: A case report and review of the literature.

He JG, Jiang H, Yang BB, Lin PF.

Oncol Lett. 2013 Jun;5(6):1939-1942. Epub 2013 Apr 17.

18.

Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1h-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248).

Regueiro-Ren A, Xue QM, Swidorski JJ, Gong YF, Mathew M, Parker DD, Yang Z, Eggers B, D'Arienzo C, Sun Y, Malinowski J, Gao Q, Wu D, Langley DR, Colonno RJ, Chien C, Grasela DM, Zheng M, Lin PF, Meanwell NA, Kadow JF.

J Med Chem. 2013 Feb 28;56(4):1656-69. doi: 10.1021/jm3016377. Epub 2013 Feb 7.

PMID:
23360431
19.

Inhibitors of HIV-1 attachment. Part 11: the discovery and structure-activity relationships associated with 4,6-diazaindole cores.

Bender JA, Yang Z, Eggers B, Gong YF, Lin PF, Parker DD, Rahematpura S, Zheng M, Meanwell NA, Kadow JF.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):218-22. doi: 10.1016/j.bmcl.2012.10.118. Epub 2012 Nov 5.

PMID:
23206859
20.

Inhibitors of HIV-1 attachment. Part 10. The discovery and structure-activity relationships of 4-azaindole cores.

Wang T, Yang Z, Zhang Z, Gong YF, Riccardi KA, Lin PF, Parker DD, Rahematpura S, Mathew M, Zheng M, Meanwell NA, Kadow JF, Bender JA.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):213-7. doi: 10.1016/j.bmcl.2012.10.120. Epub 2012 Nov 7.

PMID:
23200254
21.

Inhibitors of HIV-1 attachment. Part 7: indole-7-carboxamides as potent and orally bioavailable antiviral agents.

Yeung KS, Qiu Z, Xue Q, Fang H, Yang Z, Zadjura L, D'Arienzo CJ, Eggers BJ, Riccardi K, Shi PY, Gong YF, Browning MR, Gao Q, Hansel S, Santone K, Lin PF, Meanwell NA, Kadow JF.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):198-202. doi: 10.1016/j.bmcl.2012.10.115. Epub 2012 Nov 6.

PMID:
23200252
22.

Inhibitors of HIV-1 attachment. Part 8: the effect of C7-heteroaryl substitution on the potency, and in vitro and in vivo profiles of indole-based inhibitors.

Yeung KS, Qiu Z, Yin Z, Trehan A, Fang H, Pearce B, Yang Z, Zadjura L, D'Arienzo CJ, Riccardi K, Shi PY, Spicer TP, Gong YF, Browning MR, Hansel S, Santone K, Barker J, Coulter T, Lin PF, Meanwell NA, Kadow JF.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):203-8. doi: 10.1016/j.bmcl.2012.10.117. Epub 2012 Nov 5.

PMID:
23200249
23.

Inhibitors of HIV-1 attachment. Part 9: an assessment of oral prodrug approaches to improve the plasma exposure of a tetrazole-containing derivative.

Yeung KS, Qiu Z, Yang Z, Zadjura L, D'Arienzo CJ, Browning MR, Hansel S, Huang XS, Eggers BJ, Riccardi K, Lin PF, Meanwell NA, Kadow JF.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):209-12. doi: 10.1016/j.bmcl.2012.10.125. Epub 2012 Nov 7.

PMID:
23200244
24.

Collaborative evaluation and management of students' health-related physical fitness: applications of cluster analysis and the classification tree.

Chen JA, Shih CC, Lin PF, Chen JJ, Lin KC.

Int J Adolesc Med Health. 2012;24(2):153-9. doi: 10.1515/ijamh.2012.023. Epub 2011 Nov 29.

PMID:
22909925
25.

Empirical mode decomposition based detrended sample entropy in electroencephalography for Alzheimer's disease.

Tsai PH, Lin C, Tsao J, Lin PF, Wang PC, Huang NE, Lo MT.

J Neurosci Methods. 2012 Sep 30;210(2):230-7. doi: 10.1016/j.jneumeth.2012.07.002. Epub 2012 Jul 31.

PMID:
22878177
26.

In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068.

Nowicka-Sans B, Gong YF, McAuliffe B, Dicker I, Ho HT, Zhou N, Eggers B, Lin PF, Ray N, Wind-Rotolo M, Zhu L, Majumdar A, Stock D, Lataillade M, Hanna GJ, Matiskella JD, Ueda Y, Wang T, Kadow JF, Meanwell NA, Krystal M.

Antimicrob Agents Chemother. 2012 Jul;56(7):3498-507. doi: 10.1128/AAC.00426-12. Epub 2012 Apr 30.

27.

Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment 6. Preclinical and human pharmacokinetic profiling of BMS-663749, a phosphonooxymethyl prodrug of the HIV-1 attachment inhibitor 2-(4-benzoyl-1-piperazinyl)-1-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoethanone (BMS-488043).

Kadow JF, Ueda Y, Meanwell NA, Connolly TP, Wang T, Chen CP, Yeung KS, Zhu J, Bender JA, Yang Z, Parker D, Lin PF, Colonno RJ, Mathew M, Morgan D, Zheng M, Chien C, Grasela D.

J Med Chem. 2012 Mar 8;55(5):2048-56. doi: 10.1021/jm201218m. Epub 2012 Feb 22.

PMID:
22356441
28.

[Synpolydactyly in a Chinese kindred: mutation detection, prenatal ultrasonographic and molecular diagnosis].

Jin H, Lin PF, Wang QM, Mao F, Cai Y, Gong YQ.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2011 Dec;28(6):601-5. doi: 10.3760/cma.j.issn.1003-9406.2011.06.001. Chinese.

PMID:
22161087
29.

Emergency drinking water treatment during source water pollution accidents in China: origin analysis, framework and technologies.

Zhang XJ, Chen C, Lin PF, Hou AX, Niu ZB, Wang J.

Environ Sci Technol. 2011 Jan 1;45(1):161-7. doi: 10.1021/es101987e. Epub 2010 Dec 6.

PMID:
21133359
30.

In vivo patterns of resistance to the HIV attachment inhibitor BMS-488043.

Zhou N, Nowicka-Sans B, Zhang S, Fan L, Fang J, Fang H, Gong YF, Eggers B, Langley DR, Wang T, Kadow J, Grasela D, Hanna GJ, Alexander L, Colonno R, Krystal M, Lin PF.

Antimicrob Agents Chemother. 2011 Feb;55(2):729-37. doi: 10.1128/AAC.01173-10. Epub 2010 Nov 15.

31.

[Role of Fas/FasL on apoptosis of porcine follicular granulosa cells derived from isolated follicles during culture in vitro].

Lin PF, Hao YB, Guo HL, Liu HL, Rui R.

Dongwuxue Yanjiu. 2010 Jun;31(3):268-74. doi: 10.3724/SP.J.1141.2010.03268. Chinese.

32.

[Management of nasopharyngeal stenosis after uvulopalatopharyngoplasty].

Chang HY, Lin PF, Yang BB.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010 May;45(5):429. Chinese. No abstract available.

PMID:
20654185
33.

The fatigue experiences of older Taiwanese women with breast cancer.

Tsai SL, Lin HR, Chao TY, Lin PF.

J Clin Nurs. 2010 Mar;19(5-6):867-75. doi: 10.1111/j.1365-2702.2009.03064.x.

PMID:
20500330
34.

Increased sensitivity of HIV variants selected by attachment inhibitors to broadly neutralizing antibodies.

Zhou N, Fan L, Ho HT, Nowicka-Sans B, Sun Y, Zhu Y, Hu Y, McAuliffe B, Rose B, Fang H, Wang T, Kadow J, Krystal M, Alexander L, Colonno R, Lin PF.

Virology. 2010 Jul 5;402(2):256-61. doi: 10.1016/j.virol.2010.03.033. Epub 2010 Apr 18.

35.

Protection against HIV-envelope-induced neuronal cell destruction by HIV attachment inhibitors.

Zhang S, Alexander L, Wang T, Agler M, Zhou N, Fang H, Kadow J, Clapham P, Lin PF.

Arch Virol. 2010 May;155(5):777-81. doi: 10.1007/s00705-010-0644-x. Epub 2010 Mar 19.

PMID:
20300783
36.

Utilization of in vitro Caco-2 permeability and liver microsomal half-life screens in discovering BMS-488043, a novel HIV-1 attachment inhibitor with improved pharmacokinetic properties.

Yang Z, Zadjura LM, Marino AM, D'Arienzo CJ, Malinowski J, Gesenberg C, Lin PF, Colonno RJ, Wang T, Kadow JF, Meanwell NA, Hansel SB.

J Pharm Sci. 2010 Apr;99(4):2135-52. doi: 10.1002/jps.21948.

PMID:
19780144
37.

Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 5. An evolution from indole to azaindoles leading to the discovery of 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a drug candidate that demonstrates antiviral activity in HIV-1-infected subjects.

Wang T, Yin Z, Zhang Z, Bender JA, Yang Z, Johnson G, Yang Z, Zadjura LM, D'Arienzo CJ, DiGiugno Parker D, Gesenberg C, Yamanaka GA, Gong YF, Ho HT, Fang H, Zhou N, McAuliffe BV, Eggers BJ, Fan L, Nowicka-Sans B, Dicker IB, Gao Q, Colonno RJ, Lin PF, Meanwell NA, Kadow JF.

J Med Chem. 2009 Dec 10;52(23):7778-87. doi: 10.1021/jm900843g.

PMID:
19769332
38.

Inhibition of envelope-mediated CD4+-T-cell depletion by human immunodeficiency virus attachment inhibitors.

Alexander L, Zhang S, McAuliffe B, Connors D, Zhou N, Wang T, Agler M, Kadow J, Lin PF.

Antimicrob Agents Chemother. 2009 Nov;53(11):4726-32. doi: 10.1128/AAC.00494-09. Epub 2009 Aug 31.

39.

Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives.

Wang T, Kadow JF, Zhang Z, Yin Z, Gao Q, Wu D, Parker DD, Yang Z, Zadjura L, Robinson BA, Gong YF, Spicer TP, Blair WS, Shi PY, Yamanaka G, Lin PF, Meanwell NA.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5140-5. doi: 10.1016/j.bmcl.2009.07.076. Epub 2009 Jul 18. Erratum in: Bioorg Med Chem Lett. 2010 Feb 15;20(4):1462. Spicer, Timothy P [added].

PMID:
19664921
40.

Inhibitors of HIV-1 attachment. Part 3: A preliminary survey of the effect of structural variation of the benzamide moiety on antiviral activity.

Meanwell NA, Wallace OB, Wang H, Deshpande M, Pearce BC, Trehan A, Yeung KS, Qiu Z, Wright JJ, Robinson BA, Gong YF, Wang HG, Spicer TP, Blair WS, Shi PY, Lin PF.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5136-9. doi: 10.1016/j.bmcl.2009.07.027. Epub 2009 Jul 10. Erratum in: Bioorg Med Chem Lett. 2010 Feb 15;20(4):1461. Spicer, Timothy P [added].

PMID:
19632112
41.

Integrated care for severely disabled long-term care facility residents: is it better?

Wu MP, Lin PF, Lin KJ, Sun RS, Yu WR, Peng LN, Chen LK.

Arch Gerontol Geriatr. 2010 May-Jun;50(3):315-8. doi: 10.1016/j.archger.2009.05.004. Epub 2009 Jun 10.

PMID:
19520440
42.

A pilot trial of serial 18F-fluorodeoxyglucose positron emission tomography in patients with medically inoperable stage I non-small-cell lung cancer treated with hypofractionated stereotactic body radiotherapy.

Henderson MA, Hoopes DJ, Fletcher JW, Lin PF, Tann M, Yiannoutsos CT, Williams MD, Fakiris AJ, McGarry RC, Timmerman RD.

Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3):789-95. doi: 10.1016/j.ijrobp.2009.02.051. Epub 2009 May 25.

43.

Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71.

Chen TC, Chang HY, Lin PF, Chern JH, Hsu JT, Chang CY, Shih SR.

Antimicrob Agents Chemother. 2009 Jul;53(7):2740-7. doi: 10.1128/AAC.00101-09. Epub 2009 May 4.

44.

Inhibitors of HIV-1 attachment. Part 2: An initial survey of indole substitution patterns.

Meanwell NA, Wallace OB, Fang H, Wang H, Deshpande M, Wang T, Yin Z, Zhang Z, Pearce BC, James J, Yeung KS, Qiu Z, Kim Wright JJ, Yang Z, Zadjura L, Tweedie DL, Yeola S, Zhao F, Ranadive S, Robinson BA, Gong YF, Wang HG, Spicer TP, Blair WS, Shi PY, Colonno RJ, Lin PF.

Bioorg Med Chem Lett. 2009 Apr 1;19(7):1977-81. doi: 10.1016/j.bmcl.2009.02.040. Epub 2009 Feb 13. Erratum in: Bioorg Med Chem Lett. 2010 Feb 15;20(4):1460. Spicer, Timothy P [added].

PMID:
19251416
45.

Diagnostic accuracy and variability of autorefraction by the Tracey Visual Function Analyzer and the Shin-Nippon NVision-K 5001 in relation to subjective refraction.

Cleary G, Spalton DJ, Patel PM, Lin PF, Marshall J.

Ophthalmic Physiol Opt. 2009 Mar;29(2):173-81. doi: 10.1111/j.1475-1313.2008.00627.x.

PMID:
19236587
46.

Training outcomes in colorectal cancer surgery in a district general hospital.

Khan OA, Lin PF, Chaudhuri J, Nelson M, Elsmore S, Walsh T.

Acta Chir Belg. 2008 Sep-Oct;108(5):503-7.

PMID:
19051456
47.

Entecavir exhibits inhibitory activity against human immunodeficiency virus under conditions of reduced viral challenge.

Lin PF, Nowicka-Sans B, Terry B, Zhang S, Wang C, Fan L, Dicker I, Gali V, Higley H, Parkin N, Tenney D, Krystal M, Colonno R.

Antimicrob Agents Chemother. 2008 May;52(5):1759-67. doi: 10.1128/AAC.01313-07. Epub 2008 Mar 3.

48.

X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir.

Klei HE, Kish K, Lin PF, Guo Q, Friborg J, Rose RE, Zhang Y, Goldfarb V, Langley DR, Wittekind M, Sheriff S.

J Virol. 2007 Sep;81(17):9525-35. Epub 2007 May 30.

49.

FDG-PET and stereotactic body radiotherapy (SBRT) for stage I non-small-cell lung cancer.

Hoopes DJ, Tann M, Fletcher JW, Forquer JA, Lin PF, Lo SS, Timmerman RD, McGarry RC.

Lung Cancer. 2007 May;56(2):229-34. Epub 2007 Mar 13.

PMID:
17353064
50.

Small-molecule HIV-1 gp120 inhibitors to prevent HIV-1 entry: an emerging opportunity for drug development.

Kadow J, Wang HG, Lin PF.

Curr Opin Investig Drugs. 2006 Aug;7(8):721-6. Review.

PMID:
16955683

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