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HER2-mediated internalization of cytotoxic agents in ERBB2 amplified or mutant lung cancers.

Li BT, Michelini F, Misale S, Cocco E, Baldino L, Cai Y, Shifman S, Tu HY, Myers ML, Xu C, Mattar M, Khodos I, Little M, Qeriqi B, Weitsman G, Wilhelm CJ, Lalani AS, Diala I, Freedman RA, Lin NU, Solit DB, Berger MF, Barber PR, Ng T, Offin M, Isbell JM, Jones DR, Yu HA, Thyparambil S, Liao WL, Bhalkikar A, Cecchi F, Hyman DM, Lewis JS, Buonocore DJ, Ho AL, Makker V, Reis-Filho JS, Razavi P, Arcila ME, Kris MG, Poirier JT, Shen R, Tsurutani J, Ulaner GA, de Stanchina E, Rosen N, Rudin CM, Scaltriti M.

Cancer Discov. 2020 Mar 25. pii: CD-20-0215. doi: 10.1158/2159-8290.CD-20-0215. [Epub ahead of print]


[Prevalence of human papilloma virus infection and its risk factors in some rural areas of Jiangsu, China].

Zhang RJ, Jiang ZX, Lin N, Shi H, Wang LJ, Chen W, Wu YL, Xu HQ.

Zhonghua Nan Ke Xue. 2018 Sep;24(9):795-801. Chinese.


Dihydromyricetin Prevents Diabetic Cardiomyopathy via miR-34a Suppression by Activating Autophagy.

Ni T, Lin N, Lu W, Sun Z, Lin H, Chi J, Guo H.

Cardiovasc Drugs Ther. 2020 Mar 24. doi: 10.1007/s10557-020-06968-0. [Epub ahead of print]


Copy number variations associated with fetal congenital kidney malformations.

Cai M, Lin N, Su L, Wu X, Xie X, Li Y, Chen X, Lin Y, Huang H, Xu L.

Mol Cytogenet. 2020 Mar 24;13:11. doi: 10.1186/s13039-020-00481-7. eCollection 2020.


Bit-Rate Conditions for the Consensus of Quantized Multiagent Systems Based on Event Triggering.

Lin N, Ling Q.

IEEE Trans Cybern. 2020 Mar 18. doi: 10.1109/TCYB.2020.2977969. [Epub ahead of print]


[Primary skull base chondrosarcoma: a clinicopathological analysis].

Zhang Y, Chen XN, Ren CH, Jiang CZ, Chen YP, Lin N, Wang M, Cai SS, Li GP, Zhang S, Wang XF.

Zhonghua Bing Li Xue Za Zhi. 2020 Mar 8;49(3):239-243. doi: 10.3760/cma.j.issn.0529-5807.2020.03.006. Chinese.


sRIS: a small RNA illustration system for plant next-generation sequencing data analysis.

Tseng KC, Chiang-Hsieh YF, Pai H, Wu NY, Zheng HQ, Chow CN, Lee TY, Chang SB, Lin NS, Chang WC.

Plant Cell Physiol. 2020 Mar 17. pii: pcaa034. doi: 10.1093/pcp/pcaa034. [Epub ahead of print]


An Efficient Probe of Cyclometallated Phosphorescent Iridium Complex for Selective Detection of Cyanide.

Lin N, Ou HD, Xu Q, Jin Y, Deng W, Yao ZJ.

ACS Omega. 2020 Feb 28;5(9):4636-4645. doi: 10.1021/acsomega.9b04364. eCollection 2020 Mar 10.


Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer.

Parsons HA, Rhoades J, Reed SC, Gydush G, Ram P, Exman P, Xiong K, Lo CC, Li T, Fleharty M, Kirkner GJ, Rotem D, Cohen O, Yu F, Fitarelli-Kiehl M, Leong KW, Hughes ME, Rosenberg SM, Collins LC, Miller KD, Blumenstiel B, Trippa L, Cibulskis C, Neuberg DS, DeFelice M, Freeman SS, Lennon NJ, Wagle N, Ha G, Stover DG, Choudhury AD, Getz G, Winer EP, Meyerson M, Lin NU, Krop I, Love JC, Makrigiorgos GM, Partridge AH, Mayer EL, Golub TR, Adalsteinsson V.

Clin Cancer Res. 2020 Mar 13. pii: clincanres.3005.2019. doi: 10.1158/1078-0432.CCR-19-3005. [Epub ahead of print]


Estimating breast tissue-specific DNA methylation age using next-generation sequencing data.

Castle JR, Lin N, Liu J, Storniolo AMV, Shendre A, Hou L, Horvath S, Liu Y, Wang C, He C.

Clin Epigenetics. 2020 Mar 12;12(1):45. doi: 10.1186/s13148-020-00834-4.


Does the intermittent Pringle maneuver affect the recurrence following surgical resection for hepatocellular carcinoma? A systematic review.

Lin N, Li J, Ke Q, Xin F, Zeng Y, Wang L, Liu J.

PLoS One. 2020 Mar 11;15(3):e0229870. doi: 10.1371/journal.pone.0229870. eCollection 2020.


Study of interfacial random strain fields in core-shell ZnO nanowires by scanning transmission electron microscopy.

Zhang Y, Zhang W, Sun Y, Yu H, Lu J, Lin N, Wang Z, Pan N, Wang X, Ma C.

Micron. 2020 Mar 5;133:102862. doi: 10.1016/j.micron.2020.102862. [Epub ahead of print]


Nodular regenerative hyperplasia and portal hypertension are the characteristics of liver abnormalities in patients with selective immunoglobulin A deficiency.

Li Y, Xu C, Lin N, Zhao Y, Song J.

Clin Res Hepatol Gastroenterol. 2020 Mar 4. pii: S2210-7401(20)30040-1. doi: 10.1016/j.clinre.2020.02.007. [Epub ahead of print] No abstract available.


Dissociating the neural correlates of the sociality and plausibility effects in simple conceptual combination.

Lin N, Xu Y, Yang H, Zhang G, Zhang M, Wang S, Hua H, Li X.

Brain Struct Funct. 2020 Mar 5. doi: 10.1007/s00429-020-02052-3. [Epub ahead of print]


Epidemic of influenza A(H1N1)pdm09 analyzed by full genome sequences and the first case of oseltamivir-resistant strain in Myanmar 2017.

Kyaw Win SM, Saito R, Win NC, Lasham DJ, Kyaw Y, Lin N, Thein KN, Chon I, Odagiri T, Thein W, Kyaw LL, Tin OS, Saitoh A, Tamura T, Hirokawa C, Uchida Y, Saito T, Watanabe S, Odagiri T, Kamata K, Osada H, Dapat C, Watanabe H, Tin HH.

PLoS One. 2020 Mar 4;15(3):e0229601. doi: 10.1371/journal.pone.0229601. eCollection 2020.


An Integrated Analysis of mRNA and lncRNA Expression Profiles Indicates Their Potential Contribution to Brown Fat Dysfunction With Aging.

Feng J, Xu H, Pan F, Hu J, Wu Y, Lin N, Zhang X, Ji C, Hu Y, Zhong H, Yan L, Zhong T, Cui X.

Front Endocrinol (Lausanne). 2020 Feb 17;11:46. doi: 10.3389/fendo.2020.00046. eCollection 2020.


Mesenchymal stem cell-derived exosomes protect beta cells against hypoxia-induced apoptosis via miR-21 by alleviating ER stress and inhibiting p38 MAPK phosphorylation.

Chen J, Chen J, Cheng Y, Fu Y, Zhao H, Tang M, Zhao H, Lin N, Shi X, Lei Y, Wang S, Huang L, Wu W, Tan J.

Stem Cell Res Ther. 2020 Mar 4;11(1):97. doi: 10.1186/s13287-020-01610-0.


Interleukin-1β Regulates Lipid Homeostasis in Human Glomerular Mesangial Cells.

Liu H, Deng Y, Wu L, Li Y, Lin N, Li W, Dong X, Ma L.

J Nutr Health Aging. 2020;24(3):246-250. doi: 10.1007/s12603-019-1302-y.


Dihydromyricetin alleviates doxorubicin-induced cardiotoxicity by inhibiting NLRP3 inflammasome through activation of SIRT1.

Sun Z, Lu W, Lin N, Lin H, Zhang J, Ni T, Meng L, Zhang C, Guo H.

Biochem Pharmacol. 2020 Feb 27;175:113888. doi: 10.1016/j.bcp.2020.113888. [Epub ahead of print]


Therapeutic Effects of Lithospermate B Complexed with Mg2+ or Zn2+ on Metabolic Syndrome Induced in Rats Fed with High-Fat Diet.

Hsieh SK, Lin NH, Chen YJ, Lee MR, Chen WY, Tzen JTC.

Molecules. 2020 Feb 22;25(4). pii: E983. doi: 10.3390/molecules25040983.


Integrated Chinese Herbal Medicine and Western Medicine on the Survival in Patients with Colorectal Cancer: A Retrospective Study of Medical Records.

Yeh MH, Chiu HP, Wu MC, Koo M, Lin NW, Liao KK, Yeh CC, Li TM.

Evid Based Complement Alternat Med. 2020 Jan 13;2020:4561040. doi: 10.1155/2020/4561040. eCollection 2020.


Key factor on improving secondary advanced dewatering performance of municipal dewatered sludge: Selective oxidative decomposition of polysaccharides.

Lin N, Zhu W, Fan X, Wang C, Chen C, Zhang H, Chen L, Wu S, Cui Y.

Chemosphere. 2020 Feb 5;249:126108. doi: 10.1016/j.chemosphere.2020.126108. [Epub ahead of print]


Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today.

Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP.

Int J Radiat Oncol Biol Phys. 2020 Feb 19. pii: S0360-3016(20)30205-4. doi: 10.1016/j.ijrobp.2020.01.051. [Epub ahead of print]


The effect of adjuvant therapy for patients with intrahepatic cholangiocarcinoma after surgical resection: A systematic review and meta-analysis.

Ke Q, Lin N, Deng M, Wang L, Zeng Y, Liu J.

PLoS One. 2020 Feb 21;15(2):e0229292. doi: 10.1371/journal.pone.0229292. eCollection 2020.


Reducing end modification on cellulose nanocrystals: strategy, characterization, applications and challenges.

Tao H, Lavoine N, Jiang F, Tang J, Lin N.

Nanoscale Horiz. 2020 Feb 19. doi: 10.1039/d0nh00016g. [Epub ahead of print] Review.


Glycyrrhizin inhibits osteoarthritis development through suppressing the PI3K/AKT/NF-κB signaling pathway in vivo and in vitro.

Jiang RH, Xu JJ, Zhu DC, Li JF, Zhang CX, Lin N, Gao WY.

Food Funct. 2020 Mar 1;11(3):2126-2136. doi: 10.1039/c9fo02241d. Epub 2020 Feb 19.


A natural anthraquinone derivative shikonin synergizes with AZD9291 against wtEGFR NSCLC cells through reactive oxygen species-mediated endoplasmic reticulum stress.

Hu X, Zhang ZY, Wu LW, Zeng LH, Chen H, Zhu HJ, Zhang JK, Shao J, Zhang C, Li YL, Lin NM.

Phytomedicine. 2020 Mar;68:153189. doi: 10.1016/j.phymed.2020.153189. Epub 2020 Feb 10.


TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancer.

Vaklavas C, Roberts BS, Varley KE, Lin NU, Liu MC, Rugo HS, Puhalla S, Nanda R, Storniolo AM, Carey LA, Saleh MN, Li Y, Delossantos JF, Grizzle WE, LoBuglio AF, Myers RM, Forero-Torres A; Translational Breast Cancer Research Consortium (TBCRC).

Breast Cancer Res. 2020 Feb 18;22(1):22. doi: 10.1186/s13058-020-01258-x.


Prevalence and mutational determinants of high tumor mutation burden in breast cancer.

Barroso-Sousa R, Jain E, Cohen O, Kim D, Buendia-Buendia J, Winer E, Lin N, Tolaney SM, Wagle N.

Ann Oncol. 2020 Mar;31(3):387-394. doi: 10.1016/j.annonc.2019.11.010. Epub 2020 Jan 9.


Preparation and surface modification of crab nanochitin for organogels based on thiol-ene click cross-linking.

Kiliona KPS, Zhou M, Zhu Y, Lan P, Lin N.

Int J Biol Macromol. 2020 Feb 13;150:756-764. doi: 10.1016/j.ijbiomac.2020.02.125. [Epub ahead of print]


Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases (BTIP-BM).

Kaufmann TJ, Smits M, Boxerman J, Huang R, Barboriak DP, Weller M, Chung C, Tsien C, Brown PD, Shankar L, Galanis E, Gerstner E, van den Bent MJ, Burns TC, Parney IF, Dunn G, Brastianos PK, Lin NU, Wen PY, Ellingson BM.

Neuro Oncol. 2020 Feb 12. pii: noaa030. doi: 10.1093/neuonc/noaa030. [Epub ahead of print]


Chlorella sorokiniana Extract Prevents Cisplatin-Induced Myelotoxicity In Vitro and In Vivo.

Lin SH, Li MH, Chuang KA, Lin NH, Chang CH, Wu HC, Chao YH, Lin CC, Pan IH, Perng MD, Wen SF.

Oxid Med Cell Longev. 2020 Jan 25;2020:7353618. doi: 10.1155/2020/7353618. eCollection 2020.


LZAP promotes the proliferation and invasiveness of cervical carcinoma cells by targeting AKT and EMT.

Dai YF, Lin N, He DQ, Xu M, Zhong LY, He SQ, Guo DH, Li Y, Huang HL, Zheng XQ, Xu LP.

J Cancer. 2020 Jan 14;11(6):1625-1633. doi: 10.7150/jca.39359. eCollection 2020.


A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa-dependent apoptosis in human pancreatic cancer cells.

Yan YY, Shi KY, Teng F, Chen J, Che JX, Dong XW, Lin NM, Zhang B.

Acta Pharmacol Sin. 2020 Feb 11. doi: 10.1038/s41401-019-0354-1. [Epub ahead of print]


Estrogen, Progesterone and HER2 Receptor Discordance Between Primary Tumor and Brain Metastases in Breast Cancer and Its Effect on Treatment and Survival.

Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP.

Neuro Oncol. 2020 Feb 8. pii: noaa025. doi: 10.1093/neuonc/noaa025. [Epub ahead of print]


Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis.

Fritz BA, King CR, Ben Abdallah A, Lin N, Mickle AM, Budelier TP, Oberhaus J, Park D, Maybrier HR, Wildes TS, Avidan MS, Apakama G, Aranake-Chrisinger A, Bolzenius J, Burton J, Cui V, Emmert DA, Goswami S, Graetz TJ, Gupta S, Jordan K, Kronzer A, McKinnon SL, Muench MR, Murphy MR, Palanca BJ, Patel A, Spencer JW, Stevens TW, Strutz P, Tedeschi CM, Torres BA, Trammel ER, Upadhyayula RT, Winter AC, Jacobsohn E, Fong T, Gallagher J, Inouye SK, Schmitt EM, Somerville E, Stark S, Lenze EJ, Melby SJ, Tappenden J; ENGAGES Research Group.

Anesthesiology. 2020 Feb 5. doi: 10.1097/ALN.0000000000003181. [Epub ahead of print]


Toxicity, gut microbiota and metabolome effects after copper exposure during early life in SD rats.

Dai J, Yang X, Yuan Y, Jia Y, Liu G, Lin N, Xiao H, Zhang L, Chen J.

Toxicology. 2020 Mar 30;433-434:152395. doi: 10.1016/j.tox.2020.152395. Epub 2020 Feb 3.


Pregnancy Impacts Entecavir Pharmacokinetics but Does Not Alter Its Renal Excretion.

Lu S, Yang X, Jiang T, Zhou H, Wang W, Lin N, Zeng S, Ma Z, Jiang H.

J Pharm Sci. 2020 Feb 4. pii: S0022-3549(20)30067-8. doi: 10.1016/j.xphs.2020.01.027. [Epub ahead of print]


Tumor mutational burden and PTEN alterations as molecular correlates of response to PD-1/L1 blockade in metastatic triple-negative breast cancer.

Barroso-Sousa R, Keenan TE, Pernas S, Exman P, Jain E, Garrido-Castro AC, Hughes ME, Bychkovsky B, Umeton R, Files JL, Lindeman NI, MacConaill LE, Hodi FS, Krop I, Dillon DA, Winer EP, Wagle N, Lin NU, Mittendorf EA, Van Allen EM, Tolaney SM.

Clin Cancer Res. 2020 Feb 4. pii: clincanres.3507.2019. doi: 10.1158/1078-0432.CCR-19-3507. [Epub ahead of print]


The risk of febrile seizures following influenza and 13-valent pneumococcal conjugate vaccines.

Baker MA, Jankosky C, Yih WK, Gruber S, Li L, Cocoros NM, Lipowicz H, Coronel-Moreno C, DeLuccia S, Lin ND, McMahill-Walraven CN, Menschik D, Selvan MS, Selvam N, Chen Tilney R, Zichittella L, Lee GM, Kawai AT.

Vaccine. 2020 Feb 24;38(9):2166-2171. doi: 10.1016/j.vaccine.2020.01.046. Epub 2020 Feb 1.


Spatial heterogeneities of current and future hurricane flood risk along the U.S. Atlantic and Gulf coasts.

Sajjad M, Lin N, Chan JCL.

Sci Total Environ. 2020 Apr 15;713:136704. doi: 10.1016/j.scitotenv.2020.136704. Epub 2020 Jan 15.


Exploring and characterizing a novel combination of paeoniflorin and talatizidine for the treatment of rheumatoid arthritis.

Mao X, Li W, Chen W, Li Y, Wang Q, Wang X, Pi Z, Wang D, Xu H, Guo Q, Wu S, Cheng W, Zhang Y, Lin N.

Pharmacol Res. 2020 Mar;153:104658. doi: 10.1016/j.phrs.2020.104658. Epub 2020 Jan 27.


Amidation-Dominated Re-Assembly Strategy for Single-Atom Design/Nano-Engineering: Constructing Ni/S/C Nanotubes with Fast and Stable K-Storage.

Yi Z, Jiang S, Tian J, Qian Y, Chen S, Wei S, Lin N, Qian Y.

Angew Chem Int Ed Engl. 2020 Jan 30. doi: 10.1002/anie.201916370. [Epub ahead of print]


A Discovery of Clinically Approved Formula FBRP for Repositioning to Treat HCC by Inhibiting PI3K/AKT/NF-κB Activation.

Zhang Y, Mao X, Chen W, Guo X, Yu L, Jiang F, Wang X, Li W, Guo Q, Li T, Lin N.

Mol Ther Nucleic Acids. 2020 Mar 6;19:890-904. doi: 10.1016/j.omtn.2019.12.023. Epub 2020 Jan 10.


A useful treatment for recurrent secondary hyperparathyroidism after Parathyroidectomy: A case report.

Lin N, Fang Y, Yu C, Wang Y.

Asian J Surg. 2020 Apr;43(4):573-574. doi: 10.1016/j.asjsur.2019.12.003. Epub 2020 Jan 21. No abstract available.


Long non-coding RNA SUMO1P3 promotes hepatocellular carcinoma progression through activating Wnt/β-catenin signalling pathway by targeting miR-320a.

Wu S, Chen S, Lin N, Yang J.

J Cell Mol Med. 2020 Mar;24(5):3108-3116. doi: 10.1111/jcmm.14977. Epub 2020 Jan 22.


China's ecological conservation redline: A solution for future nature conservation.

Gao J, Wang Y, Zou C, Xu D, Lin N, Wang L, Zhang K.

Ambio. 2020 Jan 22. doi: 10.1007/s13280-019-01307-6. [Epub ahead of print]


Subtype switching in breast cancer brain metastases: a multicenter analysis.

Hulsbergen AFC, Claes A, Kavouridis VK, Ansaripour A, Nogarede C, Hughes ME, Smith TR, Brastianos PK, Verhoeff JJC, Lin NU, Broekman MLD.

Neuro Oncol. 2020 Jan 23. pii: noaa013. doi: 10.1093/neuonc/noaa013. [Epub ahead of print]


Rapid quantification of tenofovir in umbilical cord plasma and amniotic fluid in hepatitis B mono-infected pregnant women during labor by Ultra Performance Liquid Chromatography/Tandem Mass Spectrometry.

Ma Z, Li S, He D, Wang Y, Jiang H, Zhou H, Jin J, Lin N.

Rapid Commun Mass Spectrom. 2020 Jan 20:e8728. doi: 10.1002/rcm.8728. [Epub ahead of print]


Systemic therapy following craniotomy in patients with a solitary breast cancer brain metastasis.

Hulsbergen AFC, Cho LD, Mammi M, Lamba N, Smith TR, Brastianos PK, Broekman MLD, Lin NU.

Breast Cancer Res Treat. 2020 Feb;180(1):147-155. doi: 10.1007/s10549-020-05531-7. Epub 2020 Jan 17.

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