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T1ρ, T2 mapping, and EPIC-µCT Imaging in a Canine Model of Knee Osteochondral Injury.

Franklin SP, Stoker AM, Lin ASP, Pownder SL, Burke EE, Bozynski CC, Kuroki K, Guldberg RE, Cook JL, Holmes SP.

J Orthop Res. 2019 Aug 20. doi: 10.1002/jor.24450. [Epub ahead of print]


Analytics-statistics mixed training and its fitness to semisupervised manufacturing.

Parashar P, Chen CH, Akbar C, Fu SM, Rawat TS, Pratik S, Butola R, Chen SH, Lin AS.

PLoS One. 2019 Aug 13;14(8):e0220607. doi: 10.1371/journal.pone.0220607. eCollection 2019.


Severity in sustained attention impairment and clozapine-resistant schizophrenia: a retrospective study.

Lin AS, Chan HY, Peng YC, Chen WJ.

BMC Psychiatry. 2019 Jul 12;19(1):220. doi: 10.1186/s12888-019-2204-6.


Reduced Size Profile of Amniotic Membrane Particles Decreases Osteoarthritis Therapeutic Efficacy.

Reece DS, Burnsed OA, Parchinski K, Marr EE, White RM, Salazar-Noratto GE, Lin ASP, Willett NJ, Guldberg RE.

Tissue Eng Part A. 2019 Sep 20. doi: 10.1089/ten.TEA.2019.0074. [Epub ahead of print]


In Situ Molecular Architecture of the Helicobacter pylori Cag Type IV Secretion System.

Hu B, Khara P, Song L, Lin AS, Frick-Cheng AE, Harvey ML, Cover TL, Christie PJ.

MBio. 2019 May 14;10(3). pii: e00849-19. doi: 10.1128/mBio.00849-19.


Added sugar and dietary fiber consumption are associated with creativity in preadolescent children.

Hassevoort KM, Lin AS, Khan NA, Hillman CH, Cohen NJ.

Nutr Neurosci. 2018 Dec 18:1-12. doi: 10.1080/1028415X.2018.1558003. [Epub ahead of print]


Role of a Stem-Loop Structure in Helicobacter pylori cagA Transcript Stability.

Loh JT, Lin AS, Beckett AC, McClain MS, Cover TL.

Infect Immun. 2019 Jan 24;87(2). pii: e00692-18. doi: 10.1128/IAI.00692-18. Print 2019 Feb.


Porous PEEK improves the bone-implant interface compared to plasma-sprayed titanium coating on PEEK.

Torstrick FB, Lin ASP, Potter D, Safranski DL, Sulchek TA, Gall K, Guldberg RE.

Biomaterials. 2018 Dec;185:106-116. doi: 10.1016/j.biomaterials.2018.09.009. Epub 2018 Sep 13.


Clinical Outcome and Management for Geriatric Traumatic Injury: Analysis of 2688 Cases in the Emergency Department of a Teaching Hospital in Taiwan.

Wu MY, Chen YL, Yiang GT, Li CJ, Lin AS.

J Clin Med. 2018 Sep 4;7(9). pii: E255. doi: 10.3390/jcm7090255.


Helicobacter pylori genetic diversification in the Mongolian gerbil model.

Beckett AC, Loh JT, Chopra A, Leary S, Lin AS, McDonnell WJ, Dixon BREA, Noto JM, Israel DA, Peek RM Jr, Mallal S, Algood HMS, Cover TL.

PeerJ. 2018 May 18;6:e4803. doi: 10.7717/peerj.4803. eCollection 2018.


Biological evaluation and finite-element modeling of porous poly(para-phenylene) for orthopaedic implants.

Ahn H, Patel RR, Hoyt AJ, Lin ASP, Torstrick FB, Guldberg RE, Frick CP, Carpenter RD, Yakacki CM, Willett NJ.

Acta Biomater. 2018 May;72:352-361. doi: 10.1016/j.actbio.2018.03.025. Epub 2018 Mar 18.


Contrast enhanced μCT imaging of early articular changes in a pre-clinical model of osteoarthritis.

Reece DS, Thote T, Lin ASP, Willett NJ, Guldberg RE.

Osteoarthritis Cartilage. 2018 Jan;26(1):118-127. doi: 10.1016/j.joca.2017.10.017. Epub 2017 Oct 28.


Whole genome gene expression changes and hematological effects of rikkunshito in patients with advanced non-small cell lung cancer receiving first line chemotherapy.

Chen YC, Lin AS, Hung YC, Chen KD, Wu CY, Lie CH, Hsiao CC, Chen CJ, Liu SF, Fang WF, Chang JC, Wang TY, Wang YH, Chung YH, Chao TY, Leung SY, Su MC, Lin MC.

Exp Ther Med. 2017 Sep;14(3):2040-2052. doi: 10.3892/etm.2017.4773. Epub 2017 Jul 11.



Gustavsen KA, Stanhope KL, Lin AS, Graham JL, Havel PJ, Paul-Murphy JR.

J Zoo Wildl Med. 2016 Sep;47(3):760-769.


The effect of contouring on fatigue resistance of three types of fracture fixation plates.

Lin AS, Fechter CM, Magill M, Wipf F, Moore T, Guldberg RE.

J Orthop Surg Res. 2016 Sep 26;11(1):107.


Risk factors of multidrug-resistant Acinetobacter baumannii recurrence after successful eradication in ventilated patients.

Lin CY, Chen YM, Lin MC, Chang YP, Chao TY, Wang CC, Tsai YC, Shen LS, Li CL, Lin AS.

Biomed J. 2016 Apr;39(2):130-8. doi: 10.1016/ Epub 2016 Jun 10.


Influence of structural load-bearing scaffolds on mechanical load- and BMP-2-mediated bone regeneration.

McDermott AM, Mason DE, Lin ASP, Guldberg RE, Boerckel JD.

J Mech Behav Biomed Mater. 2016 Sep;62:169-181. doi: 10.1016/j.jmbbm.2016.05.010. Epub 2016 May 12.


"Do-it-yourself in vitro vasculature that recapitulates in vivo geometries for investigating endothelial-blood cell interactions".

Mannino RG, Myers DR, Ahn B, Wang Y, Margo Rollins, Gole H, Lin AS, Guldberg RE, Giddens DP, Timmins LH, Lam WA.

Sci Rep. 2015 Jul 23;5:12401. doi: 10.1038/srep12401.


Co-upregulation of Toll-like receptors 2 and 6 on peripheral blood cells in patients with obstructive sleep apnea.

Chen YC, Su MC, Liou CW, Liu SF, Chen CJ, Lin HC, Hsiao CC, Wang TY, Wang CC, Chin CH, Huang KT, Lin AS, Lin MC.

Sleep Breath. 2015 Sep;19(3):873-82. doi: 10.1007/s11325-014-1116-4. Epub 2015 Jan 22.


Minor physical anomalies and craniofacial measures in patients with treatment-resistant schizophrenia.

Lin AS, Chang SS, Lin SH, Peng YC, Hwu HG, Chen WJ.

Psychol Med. 2015 Jul;45(9):1839-50. doi: 10.1017/S0033291714002931. Epub 2014 Dec 17.


High-strength, surface-porous polyether-ether-ketone for load-bearing orthopedic implants.

Evans NT, Torstrick FB, Lee CS, Dupont KM, Safranski DL, Chang WA, Macedo AE, Lin AS, Boothby JM, Whittingslow DC, Carson RA, Guldberg RE, Gall K.

Acta Biomater. 2015 Feb;13:159-67. doi: 10.1016/j.actbio.2014.11.030. Epub 2014 Nov 24.


Acute and long-term behavioral outcome of infants and children exposed in utero to either maternal depression or antidepressants: a review of the literature.

Suri R, Lin AS, Cohen LS, Altshuler LL.

J Clin Psychiatry. 2014 Oct;75(10):e1142-52. doi: 10.4088/JCP.13r08926. Review.


EPIC-μCT imaging of articular cartilage.

Lin AS, Salazar-Noratto GE, Guldberg RE.

Methods Mol Biol. 2015;1226:131-40. doi: 10.1007/978-1-4939-1619-1_11.


CCR2 elimination in mice results in larger and stronger tibial bones but bone loss is not attenuated following ovariectomy or muscle denervation.

Mader TL, Novotny SA, Lin AS, Guldberg RE, Lowe DA, Warren GL.

Calcif Tissue Int. 2014 Nov;95(5):457-66. doi: 10.1007/s00223-014-9914-z. Epub 2014 Sep 19.


Aberrant Toll-like receptor 2 promoter methylation in blood cells from patients with pulmonary tuberculosis.

Chen YC, Hsiao CC, Chen CJ, Chao TY, Leung SY, Liu SF, Wang CC, Wang TY, Chang JC, Wu CC, Lin AS, Wang YH, Lin MC.

J Infect. 2014 Dec;69(6):546-57. doi: 10.1016/j.jinf.2014.08.014. Epub 2014 Sep 9.


The effect of conditional inactivation of beta 1 integrins using twist 2 Cre, Osterix Cre and osteocalcin Cre lines on skeletal phenotype.

Shekaran A, Shoemaker JT, Kavanaugh TE, Lin AS, LaPlaca MC, Fan Y, Guldberg RE, García AJ.

Bone. 2014 Nov;68:131-41. doi: 10.1016/j.bone.2014.08.008. Epub 2014 Aug 27.


Low intensity, high frequency vibration training to improve musculoskeletal function in a mouse model of Duchenne muscular dystrophy.

Novotny SA, Mader TL, Greising AG, Lin AS, Guldberg RE, Warren GL, Lowe DA.

PLoS One. 2014 Aug 14;9(8):e104339. doi: 10.1371/journal.pone.0104339. eCollection 2014.


Bone regeneration using an alpha 2 beta 1 integrin-specific hydrogel as a BMP-2 delivery vehicle.

Shekaran A, García JR, Clark AY, Kavanaugh TE, Lin AS, Guldberg RE, García AJ.

Biomaterials. 2014 Jul;35(21):5453-61. doi: 10.1016/j.biomaterials.2014.03.055. Epub 2014 Apr 13.


Particulated Juvenile Articular Cartilage Implantation in the Knee: A 3-Year EPIC-µCT and Histological Examination.

Stevens HY, Shockley BE, Willett NJ, Lin AS, Raji Y, Guldberg RE, Labib SA.

Cartilage. 2014 Apr;5(2):74-7. doi: 10.1177/1947603513515483.


Intra-articular injection of micronized dehydrated human amnion/chorion membrane attenuates osteoarthritis development.

Willett NJ, Thote T, Lin AS, Moran S, Raji Y, Sridaran S, Stevens HY, Guldberg RE.

Arthritis Res Ther. 2014 Feb 6;16(1):R47. doi: 10.1186/ar4476.


Receptor-interacting protein 1 increases chemoresistance by maintaining inhibitor of apoptosis protein levels and reducing reactive oxygen species through a microRNA-146a-mediated catalase pathway.

Wang Q, Chen W, Bai L, Chen W, Padilla MT, Lin AS, Shi S, Wang X, Lin Y.

J Biol Chem. 2014 Feb 28;289(9):5654-63. doi: 10.1074/jbc.M113.526152. Epub 2014 Jan 14.


Contrast-enhanced microCT (EPIC-μCT) ex vivo applied to the mouse and human jaw joint.

Renders GA, Mulder L, Lin AS, Langenbach GE, Koolstra JH, Guldberg RE, Everts V.

Dentomaxillofac Radiol. 2014;43(2):20130098. doi: 10.1259/dmfr.20130098. Epub 2013 Dec 18.


An open-label, randomized, controlled trial of zotepine and risperidone for acutely ill, hospitalized, schizophrenic patients with symptoms of agitation.

Chan HY, Lin AS, Chen KP, Cheng JS, Chen YY, Tsai CJ.

J Clin Psychopharmacol. 2013 Dec;33(6):747-52. doi: 10.1097/JCP.0b013e31829e8168.


Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration.

Thote T, Lin AS, Raji Y, Moran S, Stevens HY, Hart M, Kamath RV, Guldberg RE, Willett NJ.

Osteoarthritis Cartilage. 2013 Aug;21(8):1132-41. doi: 10.1016/j.joca.2013.05.018. Epub 2013 Jun 6.


Correction to first total synthesis of protoapigenone and its analogues as potent cytotoxic agents.

Lin AS, Nakagawa-Goto K, Chang FR, Yu D, Morris-Natschke SL, Wu CC, Chen SL, Wu YC, Lee KH.

J Med Chem. 2012 Aug 9;55(15):6985. Epub 2012 Jul 20. No abstract available.


Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis.

Lin MW, Lin AS, Wu DC, Wang SS, Chang FR, Wu YC, Huang YB.

Food Chem Toxicol. 2012 Dec;50(12):4333-9. doi: 10.1016/j.fct.2012.05.029. Epub 2012 May 23.


Prednisolone treatment and restricted physical activity further compromise bone of mdx mice.

Novotny SA, Warren GL, Lin AS, Guldberg RE, Baltgalvis KA, Lowe DA.

J Musculoskelet Neuronal Interact. 2012 Mar;12(1):16-23.


Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis.

Xie L, Lin AS, Kundu K, Levenston ME, Murthy N, Guldberg RE.

Arthritis Rheum. 2012 Jun;64(6):1899-908. doi: 10.1002/art.34370. Epub 2012 Jan 9.


Effects of in vivo mechanical loading on large bone defect regeneration.

Boerckel JD, Kolambkar YM, Stevens HY, Lin AS, Dupont KM, Guldberg RE.

J Orthop Res. 2012 Jul;30(7):1067-75. doi: 10.1002/jor.22042. Epub 2011 Dec 14.


Pregnenolone derivatives as potential anticancer agents.

Iqbal Choudhary M, Shahab Alam M, Atta-Ur-Rahman, Yousuf S, Wu YC, Lin AS, Shaheen F.

Steroids. 2011 Dec 20;76(14):1554-9. doi: 10.1016/j.steroids.2011.09.006. Epub 2011 Sep 22.


The offset V osteotomy versus the modified Austin with a longer plantar arm: a comparison of mechanical stability.

Ravenell RA, Kihm CA, Lin AS, Garing FX.

J Foot Ankle Surg. 2011 Mar-Apr;50(2):201-6. doi: 10.1053/j.jfas.2010.12.012.


Bone is functionally impaired in dystrophic mice but less so than skeletal muscle.

Novotny SA, Warren GL, Lin AS, Guldberg RE, Baltgalvis KA, Lowe DA.

Neuromuscul Disord. 2011 Mar;21(3):183-93. doi: 10.1016/j.nmd.2010.12.002. Epub 2011 Jan 21.


A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species.

Chen HM, Chang FR, Hsieh YC, Cheng YJ, Hsieh KC, Tsai LM, Lin AS, Wu YC, Yuan SS.

Free Radic Biol Med. 2011 May 1;50(9):1151-62. doi: 10.1016/j.freeradbiomed.2011.01.015. Epub 2011 Jan 20.


Structure and biological evaluation of novel cytotoxic sterol glycosides from the marine red alga Peyssonnelia sp.

Lin AS, Engel S, Smith BA, Fairchild CR, Aalbersberg W, Hay ME, Kubanek J.

Bioorg Med Chem. 2010 Dec 1;18(23):8264-9. doi: 10.1016/j.bmc.2010.10.010. Epub 2010 Oct 28.


Suprachoroidal drug delivery to the back of the eye using hollow microneedles.

Patel SR, Lin AS, Edelhauser HF, Prausnitz MR.

Pharm Res. 2011 Jan;28(1):166-76. doi: 10.1007/s11095-010-0271-y. Epub 2010 Sep 21.


Hyaluronic acid hydrogels with controlled degradation properties for oriented bone regeneration.

Patterson J, Siew R, Herring SW, Lin AS, Guldberg R, Stayton PS.

Biomaterials. 2010 Sep;31(26):6772-81. doi: 10.1016/j.biomaterials.2010.05.047. Epub 2010 Jun 23.


Sustained VEGF delivery via PLGA nanoparticles promotes vascular growth.

Golub JS, Kim YT, Duvall CL, Bellamkonda RV, Gupta D, Lin AS, Weiss D, Robert Taylor W, Guldberg RE.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1959-65. doi: 10.1152/ajpheart.00199.2009. Epub 2010 Mar 12.


Bioactive bromophycolides R-U from the Fijian red alga Callophycus serratus.

Lin AS, Stout EP, Prudhomme J, Le Roch K, Fairchild CR, Franzblau SG, Aalbersberg W, Hay ME, Kubanek J.

J Nat Prod. 2010 Feb 26;73(2):275-8. doi: 10.1021/np900686w.


Nondestructive assessment of sGAG content and distribution in normal and degraded rat articular cartilage via EPIC-microCT.

Xie L, Lin AS, Guldberg RE, Levenston ME.

Osteoarthritis Cartilage. 2010 Jan;18(1):65-72. doi: 10.1016/j.joca.2009.07.014. Epub 2009 Sep 1.


Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4.

Xie C, Liang B, Xue M, Lin AS, Loiselle A, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X.

Am J Pathol. 2009 Aug;175(2):772-85. doi: 10.2353/ajpath.2009.081099. Epub 2009 Jul 23.

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