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Anti-inflammatory effect of afatinib (an EGFR-TKI) on OGD-induced neuroinflammation.

Chen YJ, Hsu CC, Shiao YJ, Wang HT, Lo YL, Lin AMY.

Sci Rep. 2019 Feb 21;9(1):2516. doi: 10.1038/s41598-019-38676-7.


Less Than Ideal.

Lin AM, Lin MP, Markovic D, Ovbiagele B, Sanossian N, Towfighi A.

Stroke. 2018 Dec 7:STROKEAHA118022644. doi: 10.1161/STROKEAHA.118.022644. [Epub ahead of print]


Itraconazole as a Noncastrating Treatment for Biochemically Recurrent Prostate Cancer: A Phase 2 Study.

Lee M, Hong H, Kim W, Zhang L, Friedlander TW, Fong L, Lin AM, Small EJ, Wei XX, Rodvelt TJ, Miralda B, Stocksdale B, Ryan CJ, Aggarwal R.

Clin Genitourin Cancer. 2019 Feb;17(1):e92-e96. doi: 10.1016/j.clgc.2018.09.013. Epub 2018 Sep 24.


Clockwise and Counterclockwise Le Fort I Movements Influence Nasolabial Morphology Differently.

Sawh-Martinez R, Lin AM, DeSesa CR, Wu RT, Gary CS, Steinbacher DM.

Plast Reconstr Surg. 2018 Dec;142(6):1572-1581. doi: 10.1097/PRS.0000000000004988.


MicroRNA-224 down-regulates Glycine N-methyltransferase gene expression in Hepatocellular Carcinoma.

Hung JH, Li CH, Yeh CH, Huang PC, Fang CC, Chen YF, Lee KJ, Chou CH, Cheng HY, Huang HD, Chen M, Tsai TF, Lin AM, Yen CH, Tsou AP, Tyan YC, Chen YA.

Sci Rep. 2018 Aug 16;8(1):12284. doi: 10.1038/s41598-018-30682-5.


A Phase II Trial of Selinexor, an Oral Selective Inhibitor of Nuclear Export Compound, in Abiraterone- and/or Enzalutamide-Refractory Metastatic Castration-Resistant Prostate Cancer.

Wei XX, Siegel AP, Aggarwal R, Lin AM, Friedlander TW, Fong L, Kim W, Louttit M, Chang E, Zhang L, Ryan CJ.

Oncologist. 2018 Jun;23(6):656-e64. doi: 10.1634/theoncologist.2017-0624. Epub 2018 Feb 27.


Impact of Patient Subtype and Surgical Variables on Abdominoplasty Outcomes: A 12-Year Massachusetts General Hospital Experience.

Seth AK, Lin AM, Austen WG Jr, Gilman RH, Gallico GG 3rd, Colwell AS.

Plast Reconstr Surg. 2017 Nov;140(5):899-908. doi: 10.1097/PRS.0000000000003816.


Neuroprotective Effects of Baicalein on Acrolein-induced Neurotoxicity in the Nigrostriatal Dopaminergic System of Rat Brain.

Zhao WZ, Wang HT, Huang HJ, Lo YL, Lin AM.

Mol Neurobiol. 2018 Jan;55(1):130-137. doi: 10.1007/s12035-017-0725-x.


Soluble Epoxide Hydrolase Inhibition Attenuates MPTP-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System: Involvement of α-Synuclein Aggregation and ER Stress.

Huang HJ, Wang YT, Lin HC, Lee YH, Lin AM.

Mol Neurobiol. 2018 Jan;55(1):138-144. doi: 10.1007/s12035-017-0726-9.


High-Dose Abiraterone Acetate in Men With Castration Resistant Prostate Cancer.

Friedlander TW, Graff JN, Zejnullahu K, Anantharaman A, Zhang L, Paz R, Premasekharan G, Russell C, Huang Y, Kim W, Aggarwal RR, Lin AM, Fong L, Alumkal JJ, Beer TM, Sharifi N, Alyamani M, Dittamore R, Small EJ, Paris PL, Ryan CJ.

Clin Genitourin Cancer. 2017 Dec;15(6):733-741.e1. doi: 10.1016/j.clgc.2017.05.026. Epub 2017 Jun 3.


Acrolein acts as a neurotoxin in the nigrostriatal dopaminergic system of rat: involvement of α-synuclein aggregation and programmed cell death.

Wang YT, Lin HC, Zhao WZ, Huang HJ, Lo YL, Wang HT, Lin AM.

Sci Rep. 2017 Apr 12;7:45741. doi: 10.1038/srep45741.


Long-Term Health-Related Quality of Life Outcomes in Digital Replantation versus Revision Amputation.

Tessler O, Bartow MJ, Tremblay-Champagne MP, Lin AM, Landes G, Sebbag S, Nikolis A.

J Reconstr Microsurg. 2017 Jul;33(6):446-451. doi: 10.1055/s-0037-1601052. Epub 2017 Mar 22.


A Phase I Study of Abiraterone Acetate Combined with BEZ235, a Dual PI3K/mTOR Inhibitor, in Metastatic Castration Resistant Prostate Cancer.

Wei XX, Hsieh AC, Kim W, Friedlander T, Lin AM, Louttit M, Ryan CJ.

Oncologist. 2017 May;22(5):503-e43. doi: 10.1634/theoncologist.2016-0432. Epub 2017 Mar 17.


A multicenter phase I study of cabazitaxel, mitoxantrone, and prednisone for chemotherapy-naïve patients with metastatic castration-resistant prostate cancer: A department of defense prostate cancer clinical trials consortium study.

Aggarwal R, Bryce A, Ryan CJ, Harzstark A, Derleth C, Kim W, Friedlander T, Lin AM, Rodvelt-Bagchi T, Dhawan M, Zhang L, Lee M, Siebeneck E, Hough J, Small EJ.

Urol Oncol. 2017 Apr;35(4):149.e7-149.e13. doi: 10.1016/j.urolonc.2016.11.005. Epub 2017 Feb 1.


Systemic GM-CSF Recruits Effector T Cells into the Tumor Microenvironment in Localized Prostate Cancer.

Wei XX, Chan S, Kwek S, Lewis J, Dao V, Zhang L, Cooperberg MR, Ryan CJ, Lin AM, Friedlander TW, Rini B, Kane C, Simko JP, Carroll PR, Small EJ, Fong L.

Cancer Immunol Res. 2016 Nov;4(11):948-958. Epub 2016 Sep 29.


Baicalein attenuates α-synuclein aggregation, inflammasome activation and autophagy in the MPP+-treated nigrostriatal dopaminergic system in vivo.

Hung KC, Huang HJ, Wang YT, Lin AM.

J Ethnopharmacol. 2016 Dec 24;194:522-529. doi: 10.1016/j.jep.2016.10.040. Epub 2016 Oct 11.


Nipple Loss following Nipple-Sparing Mastectomy.

Mastroianni M, Lin AM, Smith BL, Austen WG Jr, Colwell AS.

Plast Reconstr Surg. 2016 Jul;138(1):24e-30e. doi: 10.1097/PRS.0000000000002296.


Revisions in Implant-Based Breast Reconstruction: How Does Direct-to-Implant Measure Up?

Clarke-Pearson EM, Lin AM, Hertl C, Austen WG, Colwell AS.

Plast Reconstr Surg. 2016 Jun;137(6):1690-9. doi: 10.1097/PRS.0000000000002173.


Tetrahydrobiopterin ameliorates the exaggerated exercise pressor response in patients with chronic kidney disease: a randomized controlled trial.

Lin AM, Liao P, Millson EC, Quyyumi AA, Park J.

Am J Physiol Renal Physiol. 2016 May 1;310(10):F1016-25. doi: 10.1152/ajprenal.00527.2015. Epub 2016 Mar 9.


Analysis of prescription pattern and guideline adherence in the management of asthma among medical institutions and physician specialties in Taiwan between 2000 and 2010.

Chou CL, Perng DW, Lin TL, Lin AM, Chen TJ, Wu MS, Chou YC.

Clin Ther. 2015 Oct 1;37(10):2275-85. doi: 10.1016/j.clinthera.2015.07.024. Epub 2015 Aug 20.


Melatonin Ameliorates Arsenite-Induced Neurotoxicity: Involvement of Autophagy and Mitochondria.

Teng YC, Tai YI, Huang HJ, Lin AM.

Mol Neurobiol. 2015 Oct;52(2):1015-22. doi: 10.1007/s12035-015-9250-y.


Nipple-sparing mastectomy in patients with previous breast surgery: comparative analysis of 775 immediate breast reconstructions.

Frederick MJ, Lin AM, Neuman R, Smith BL, Austen WG Jr, Colwell AS.

Plast Reconstr Surg. 2015 Jun;135(6):954e-962e. doi: 10.1097/PRS.0000000000001283.


Preexisting Levels of CD4 T Cells Expressing PD-1 Are Related to Overall Survival in Prostate Cancer Patients Treated with Ipilimumab.

Kwek SS, Lewis J, Zhang L, Weinberg V, Greaney SK, Harzstark AL, Lin AM, Ryan CJ, Small EJ, Fong L.

Cancer Immunol Res. 2015 Sep;3(9):1008-16. doi: 10.1158/2326-6066.CIR-14-0227. Epub 2015 May 12.


Chloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells.

Tang MC, Wu MY, Hwang MH, Chang YT, Huang HJ, Lin AM, Yang JC.

PLoS One. 2015 Mar 25;10(3):e0119135. doi: 10.1371/journal.pone.0119135. eCollection 2015.


Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein.

Teng YC, Jeng CJ, Huang HJ, Lin AM.

Toxicol Lett. 2015 Mar 18;233(3):239-45. doi: 10.1016/j.toxlet.2015.01.018. Epub 2015 Jan 29.


Intermittent Chemotherapy as a Platform for Testing Novel Agents in Patients With Metastatic Castration-Resistant Prostate Cancer: A Department of Defense Prostate Cancer Clinical Trials Consortium Randomized Phase II Trial of Intermittent Docetaxel With Prednisone With or Without Maintenance GM-CSF.

Aggarwal RR, Beer TM, Weinberg VK, Higano C, Taplin ME, Ryan CJ, Lin AM, Alumkal J, Graff JN, Nordquist LT, Herrera I, Small EJ.

Clin Genitourin Cancer. 2015 Jun;13(3):e191-8. doi: 10.1016/j.clgc.2014.12.004. Epub 2014 Dec 9.


Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens.

Kim W, Zhang L, Wilton JH, Fetterly G, Mohler JL, Weinberg V, Morse A, Szmulewitz RZ, Friedlander TW, Fong L, Lin AM, Harzstark AL, Molina A, Small EJ, Ryan CJ.

Clin Cancer Res. 2014 Dec 15;20(24):6269-76. doi: 10.1158/1078-0432.CCR-14-1595. Epub 2014 Oct 21.


Adenine nucleotide metabolism and a role for AMP in modulating flagellar waveforms in mouse sperm.

Vadnais ML, Cao W, Aghajanian HK, Haig-Ladewig L, Lin AM, Al-Alao O, Gerton GL.

Biol Reprod. 2014 Jun;90(6):128. doi: 10.1095/biolreprod.113.114447. Epub 2014 Apr 16.


Intestinal tumor suppression in ApcMin/+ mice by prostaglandin D2 receptor PTGDR.

Tippin BL, Kwong AM, Inadomi MJ, Lee OJ, Park JM, Materi AM, Buslon VS, Lin AM, Kudo LC, Karsten SL, French SW, Narumiya S, Urade Y, Salido E, Lin HJ.

Cancer Med. 2014 Aug;3(4):1041-51. doi: 10.1002/cam4.251. Epub 2014 Apr 12.


Roles of autophagy in MPP+-induced neurotoxicity in vivo: the involvement of mitochondria and α-synuclein aggregation.

Hung KC, Huang HJ, Lin MW, Lei YP, Lin AM.

PLoS One. 2014 Mar 19;9(3):e91074. doi: 10.1371/journal.pone.0091074. eCollection 2014.


Breast reconstruction following nipple-sparing mastectomy: predictors of complications, reconstruction outcomes, and 5-year trends.

Colwell AS, Tessler O, Lin AM, Liao E, Winograd J, Cetrulo CL, Tang R, Smith BL, Austen WG Jr.

Plast Reconstr Surg. 2014 Mar;133(3):496-506. doi: 10.1097/01.prs.0000438056.67375.75.


Thiol changes during epididymal maturation: a link to flagellar angulation in mouse spermatozoa?

Ijiri TW, Vadnais ML, Huang AP, Lin AM, Levin LR, Buck J, Gerton GL.

Andrology. 2014 Jan;2(1):65-75. doi: 10.1111/j.2047-2927.2013.00147.x. Epub 2013 Nov 20.


Dear Doctor: a tool to facilitate patient-centered communication.

Farberg AS, Lin AM, Kuhn L, Flanders SA, Kim CS.

J Hosp Med. 2013 Oct;8(10):553-8. doi: 10.1002/jhm.2073. Epub 2013 Aug 28.


Male mice express spermatogenic cell-specific triosephosphate isomerase isozymes.

Ijiri TW, Vadnais ML, Lin AM, Huang AP, Cao W, Merdiushev T, Gerton GL.

Mol Reprod Dev. 2013 Oct;80(10):862-70. doi: 10.1002/mrd.22217. Epub 2013 Aug 19.


Role of HO-1 in the arsenite-induced neurotoxicity in primary cultured cortical neurons.

Teng YC, Tai YI, Lee YH, Lin AM.

Mol Neurobiol. 2013 Oct;48(2):281-7. doi: 10.1007/s12035-013-8492-9. Epub 2013 Jul 4.


Norcantharidin suppresses cell growth and migration with enhanced anticancer activity of gefitinib and cisplatin in human non-small cell lung cancer cells.

Lee YC, Lee LM, Yang CH, Lin AM, Huang YC, Hsu CC, Chen MS, Chi CW, Yin PH, Kuo CD, Liao JF, Lee HC.

Oncol Rep. 2013 Jan;29(1):237-43. doi: 10.3892/or.2012.2118. Epub 2012 Oct 31.


MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib.

Huang MH, Lee JH, Chang YJ, Tsai HH, Lin YL, Lin AM, Yang JC.

Mol Oncol. 2013 Feb;7(1):112-20. doi: 10.1016/j.molonc.2012.09.002. Epub 2012 Oct 13.


Neuroprotective effects of longan ( Dimocarpus longan Lour.) flower water extract on MPP+-induced neurotoxicity in rat brain.

Lin AM, Wu LY, Hung KC, Huang HJ, Lei YP, Lu WC, Hwang LS.

J Agric Food Chem. 2012 Sep 12;60(36):9188-94. doi: 10.1021/jf302792t. Epub 2012 Aug 31.


Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation.

Chang CF, Huang HJ, Lee HC, Hung KC, Wu RT, Lin AM.

J Pineal Res. 2012 Apr;52(3):312-21. doi: 10.1111/j.1600-079X.2011.00945.x. Epub 2011 Dec 29.


A phase II study of insulin-like growth factor receptor inhibition with nordihydroguaiaretic acid in men with non-metastatic hormone-sensitive prostate cancer.

Friedlander TW, Weinberg VK, Huang Y, Mi JT, Formaker CG, Small EJ, Harzstark AL, Lin AM, Fong L, Ryan CJ.

Oncol Rep. 2012 Jan;27(1):3-9. doi: 10.3892/or.2011.1487. Epub 2011 Oct 4.


Hematopoietic prostaglandin D synthase (HPGDS): a high stability, Val187Ile isoenzyme common among African Americans and its relationship to risk for colorectal cancer.

Tippin BL, Levine AJ, Materi AM, Song WL, Keku TO, Goodman JE, Sansbury LB, Das S, Dai A, Kwong AM, Lin AM, Lin JM, Park JM, Patterson RE, Chlebowski RT, Garavito RM, Inoue T, Cho W, Lawson JA, Kapoor S, Kolonel LN, Le Marchand L, Haile RW, Sandler RS, Lin HJ.

Prostaglandins Other Lipid Mediat. 2012 Jan;97(1-2):22-8. doi: 10.1016/j.prostaglandins.2011.07.006. Epub 2011 Jul 28.


Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus.

Villanueva E, Yalavarthi S, Berthier CC, Hodgin JB, Khandpur R, Lin AM, Rubin CJ, Zhao W, Olsen SH, Klinker M, Shealy D, Denny MF, Plumas J, Chaperot L, Kretzler M, Bruce AT, Kaplan MJ.

J Immunol. 2011 Jul 1;187(1):538-52. doi: 10.4049/jimmunol.1100450. Epub 2011 May 25.


Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis.

Lin AM, Rubin CJ, Khandpur R, Wang JY, Riblett M, Yalavarthi S, Villanueva EC, Shah P, Kaplan MJ, Bruce AT.

J Immunol. 2011 Jul 1;187(1):490-500. doi: 10.4049/jimmunol.1100123. Epub 2011 May 23.


A phase 1 study of everolimus and sorafenib for metastatic clear cell renal cell carcinoma.

Harzstark AL, Small EJ, Weinberg VK, Sun J, Ryan CJ, Lin AM, Fong L, Brocks DR, Rosenberg JE.

Cancer. 2011 Sep 15;117(18):4194-200. doi: 10.1002/cncr.25931. Epub 2011 Mar 8.


Neuroprotective effect of oral S/B remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) on iron-induced neurodegeneration in the nigrostriatal dopaminergic system of rat brain.

Lin AM, Ping YH, Chang GF, Wang JY, Chiu JH, Kuo CD, Chi CW.

J Ethnopharmacol. 2011 Apr 12;134(3):884-91. doi: 10.1016/j.jep.2011.01.056. Epub 2011 Feb 4.


Tumor fistulization associated with targeted therapy: computed tomographic findings and clinical consequences.

Chow H, Jung A, Talbott J, Lin AM, Daud AI, Coakley FV.

J Comput Assist Tomogr. 2011 Jan-Feb;35(1):86-90. doi: 10.1097/RCT.0b013e3181fce2cb.


Effect of the somatostatin analog octreotide acetate on circulating insulin-like growth factor-1 and related peptides in patients with non-metastatic castration-resistant prostate cancer: results of a phase II study.

Friedlander TW, Weinberg VK, Small EJ, Sharib J, Harzstark AL, Lin AM, Fong L, Ryan CJ.

Urol Oncol. 2012 Jul-Aug;30(4):408-14. doi: 10.1016/j.urolonc.2010.06.014. Epub 2010 Oct 2.


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