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Items: 6


In vivo genome editing improves motor function and extends survival in a mouse model of ALS.

Gaj T, Ojala DS, Ekman FK, Byrne LC, Limsirichai P, Schaffer DV.

Sci Adv. 2017 Dec 20;3(12):eaar3952. doi: 10.1126/sciadv.aar3952. eCollection 2017 Dec.


Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery.

Gaj T, Staahl BT, Rodrigues GMC, Limsirichai P, Ekman FK, Doudna JA, Schaffer DV.

Nucleic Acids Res. 2017 Jun 20;45(11):e98. doi: 10.1093/nar/gkx154.


CRISPR-mediated Activation of Latent HIV-1 Expression.

Limsirichai P, Gaj T, Schaffer DV.

Mol Ther. 2016 Mar;24(3):499-507. doi: 10.1038/mt.2015.213. Epub 2015 Nov 26.


Orthogonal control of expression mean and variance by epigenetic features at different genomic loci.

Dey SS, Foley JE, Limsirichai P, Schaffer DV, Arkin AP.

Mol Syst Biol. 2015 May 5;11(5):806. doi: 10.15252/msb.20145704.


Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1.

Calvo JA, Moroski-Erkul CA, Lake A, Eichinger LW, Shah D, Jhun I, Limsirichai P, Bronson RT, Christiani DC, Meira LB, Samson LD.

PLoS Genet. 2013 Apr;9(4):e1003413. doi: 10.1371/journal.pgen.1003413. Epub 2013 Apr 4.


Characterization of gamma-butyrolactone autoregulatory signaling gene homologs in the angucyclinone polyketide WS5995B producer Streptomyces acidiscabies.

Healy FG, Eaton KP, Limsirichai P, Aldrich JF, Plowman AK, King RR.

J Bacteriol. 2009 Aug;191(15):4786-97. doi: 10.1128/JB.00437-09. Epub 2009 May 22.

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