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Items: 17

1.

Chronic allergen exposure drives accumulation of long-lived IgE plasma cells in the bone marrow, giving rise to serological memory.

Asrat S, Kaur N, Liu X, Ben LH, Kajimura D, Murphy AJ, Sleeman MA, Limnander A, Orengo JM.

Sci Immunol. 2020 Jan 10;5(43). pii: eaav8402. doi: 10.1126/sciimmunol.aav8402.

PMID:
31924685
2.

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.

Orengo JM, Radin AR, Kamat V, Badithe A, Ben LH, Bennett BL, Zhong S, Birchard D, Limnander A, Rafique A, Bautista J, Kostic A, Newell D, Duan X, Franklin MC, Olson W, Huang T, Gandhi NA, Lipsich L, Stahl N, Papadopoulos NJ, Murphy AJ, Yancopoulos GD.

Nat Commun. 2018 Apr 12;9(1):1421. doi: 10.1038/s41467-018-03636-8.

3.

Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M.

Nature. 2016 Jun 2;534(7605):138. doi: 10.1038/nature16997. Epub 2016 Mar 9. No abstract available.

PMID:
26958840
4.

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M.

Nature. 2015 May 21;521(7552):357-61. doi: 10.1038/nature14231. Epub 2015 Mar 23. Erratum in: Nature. 2016 Jun 2;534(7605):138.

5.

RasGRP Ras guanine nucleotide exchange factors in cancer.

Ksionda O, Limnander A, Roose JP.

Front Biol (Beijing). 2013 Oct 1;8(5):508-532.

6.

Protein kinase Cδ promotes transitional B cell-negative selection and limits proximal B cell receptor signaling to enforce tolerance.

Limnander A, Zikherman J, Lau T, Leitges M, Weiss A, Roose JP.

Mol Cell Biol. 2014 Apr;34(8):1474-85. doi: 10.1128/MCB.01699-13. Epub 2014 Feb 10.

7.

Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.

Daley SR, Coakley KM, Hu DY, Randall KL, Jenne CN, Limnander A, Myers DR, Polakos NK, Enders A, Roots C, Balakishnan B, Miosge LA, Sjollema G, Bertram EM, Field MA, Shao Y, Andrews TD, Whittle B, Barnes SW, Walker JR, Cyster JG, Goodnow CC, Roose JP.

Elife. 2013 Dec 12;2:e01020. doi: 10.7554/eLife.01020.

8.

Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.

Iwig JS, Vercoulen Y, Das R, Barros T, Limnander A, Che Y, Pelton JG, Wemmer DE, Roose JP, Kuriyan J.

Elife. 2013 Jul 30;2:e00813. doi: 10.7554/eLife.00813.

9.

Ca-dependent Ras/Erk signaling mediates negative selection of autoreactive B cells.

Limnander A, Weiss A.

Small GTPases. 2011 Sep;2(5):282-288. Epub 2011 Sep 1.

10.

STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development.

Limnander A, Depeille P, Freedman TS, Liou J, Leitges M, Kurosaki T, Roose JP, Weiss A.

Nat Immunol. 2011 May;12(5):425-33. doi: 10.1038/ni.2016. Epub 2011 Mar 27.

11.

Pim-1 and Pim-2 kinases are required for efficient pre-B-cell transformation by v-Abl oncogene.

Chen JL, Limnander A, Rothman PB.

Blood. 2008 Feb 1;111(3):1677-85. Epub 2007 Nov 27.

PMID:
18042805
12.

Coupling Ca2+ store release to Icrac channel activation in B lymphocytes requires the activity of Lyn and Syk kinases.

Chung SC, Limnander A, Kurosaki T, Weiss A, Korenbrot JI.

J Cell Biol. 2007 Apr 23;177(2):317-28.

13.

Dok1 and SHIP act as negative regulators of v-Abl-induced pre-B cell transformation, proliferation and Ras/Erk activation.

Oki S, Limnander A, Yao PM, Niki M, Pandolfi PP, Rothman PB.

Cell Cycle. 2005 Feb;4(2):310-4. Epub 2005 Feb 4.

PMID:
15655368
14.

Abl oncogene bypasses normal regulation of Jak/STAT activation.

Limnander A, Rothman PB.

Cell Cycle. 2004 Dec;3(12):1486-8. Epub 2004 Dec 12. Review.

PMID:
15611644
15.

SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome.

Vuong BQ, Arenzana TL, Showalter BM, Losman J, Chen XP, Mostecki J, Banks AS, Limnander A, Fernandez N, Rothman PB.

Mol Cell Biol. 2004 Oct;24(20):9092-101. Erratum in: Mol Cell Biol. 2005 Sep;25(17):7927.

16.

v-Abl signaling disrupts SOCS-1 function in transformed pre-B cells.

Limnander A, Danial NN, Rothman PB.

Mol Cell. 2004 Aug 13;15(3):329-41.

17.

Functional involvement of Akt signaling downstream of Jak1 in v-Abl-induced activation of hematopoietic cells.

Oki S, Limnander A, Danial NN, Rothman PB.

Blood. 2002 Aug 1;100(3):966-73.

PMID:
12130510

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