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Items: 15


CCR2 Plays a Protective Role in Rocio Virus-Induced Encephalitis by Promoting Macrophage Infiltration Into the Brain.

Amarilla AA, Santos-Junior NN, Figueiredo ML, Luiz JPM, Fumagalli MJ, Colón DF, Lippi V, Alfonso HL, Lima-Junior DS, Trabuco AC, Spinieli RL, Desidera AC, Leite-Panissi CRA, Lauretti F, Mendoza SES, Silva CLA, Rego EM, Galvao-Lima LJ, Bassi GS, Penharvel Martíns SLB, Manrique WG, Alves-Filho JC, Cunha FQ, Peng NYG, Modhiran N, Setoh YX, Khromykh AA, Figueiredo LTM, Aquino VH.

J Infect Dis. 2019 May 24;219(12):2015-2025. doi: 10.1093/infdis/jiz029.


Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome.

de Carvalho RVH, Andrade WA, Lima-Junior DS, Dilucca M, de Oliveira CV, Wang K, Nogueira PM, Rugani JN, Soares RP, Beverley SM, Shao F, Zamboni DS.

Cell Rep. 2019 Jan 8;26(2):429-437.e5. doi: 10.1016/j.celrep.2018.12.047.


Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice.

Amarilla AA, Fumagalli MJ, Figueiredo ML, Lima-Junior DS, Santos-Junior NN, Alfonso HL, Lippi V, Trabuco AC, Lauretti F, Muller VD, Colón DF, Luiz JPM, Suhrbier A, Setoh YX, Khromykh AA, Figueiredo LTM, Aquino VH.

PLoS One. 2018 Jun 13;13(6):e0199071. doi: 10.1371/journal.pone.0199071. eCollection 2018.


Dectin-1 Activation during Leishmania amazonensis Phagocytosis Prompts Syk-Dependent Reactive Oxygen Species Production To Trigger Inflammasome Assembly and Restriction of Parasite Replication.

Lima-Junior DS, Mineo TWP, Calich VLG, Zamboni DS.

J Immunol. 2017 Sep 15;199(6):2055-2068. doi: 10.4049/jimmunol.1700258. Epub 2017 Aug 7.


T1/ST2 deficient mice display protection against Leishmania infantum experimental infection.

Khalid KE, Nascimento MSL, Sacramento LA, Costa DL, Lima-Júnior DS, Carregaro V, da Silva JS.

Acta Trop. 2017 Aug;172:1-6. doi: 10.1016/j.actatropica.2017.04.011. Epub 2017 Apr 17.


sCD163 levels as a biomarker of disease severity in leprosy and visceral leishmaniasis.

Silva RL, Santos MB, Almeida PL, Barros TS, Magalhães L, Cazzaniga RA, Souza PR, Luz NF, França-Costa J, Borges VM, Lima-Junior DS, Lipscomb MW, Duthie MS, Reed SG, Almeida RP, Jesus AR.

PLoS Negl Trop Dis. 2017 Mar 29;11(3):e0005486. doi: 10.1371/journal.pntd.0005486. eCollection 2017 Mar.


Nucleotide-binding oligomerization domain-containing protein 2 prompts potent inflammatory stimuli during Neospora caninum infection.

Davoli-Ferreira M, Fonseca DM, Mota CM, Dias MS, Lima-Junior DS, da Silva MV, Quirino GF, Zamboni DS, Silva JS, Mineo TW.

Sci Rep. 2016 Jul 5;6:29289. doi: 10.1038/srep29289.


Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro.

Fernandes TD, Cunha LD, Ribeiro JM, Massis LM, Lima-Junior DS, Newton HJ, Zamboni DS.

Infect Immun. 2016 Aug 19;84(9):2439-48. doi: 10.1128/IAI.00411-16. Print 2016 Sep.


CCR2 signaling contributes to the differentiation of protective inflammatory dendritic cells in Leishmania braziliensis infection.

Costa DL, Lima-Júnior DS, Nascimento MS, Sacramento LA, Almeida RP, Carregaro V, Silva JS.

J Leukoc Biol. 2016 Aug;100(2):423-32. doi: 10.1189/jlb.4A0715-288R. Epub 2016 Feb 16.


Toll-like receptor 9 signaling in dendritic cells regulates neutrophil recruitment to inflammatory foci following Leishmania infantum infection.

Sacramento L, Trevelin SC, Nascimento MS, Lima-Jùnior DS, Costa DL, Almeida RP, Cunha FQ, Silva JS, Carregaro V.

Infect Immun. 2015 Dec;83(12):4604-16. doi: 10.1128/IAI.00975-15. Epub 2015 Sep 14.


Inflammasomes in host response to protozoan parasites.

Zamboni DS, Lima-Junior DS.

Immunol Rev. 2015 May;265(1):156-71. doi: 10.1111/imr.12291. Review.


Interleukin 17A acts synergistically with interferon γ to promote protection against Leishmania infantum infection.

Nascimento MS, Carregaro V, Lima-Júnior DS, Costa DL, Ryffel B, Duthie MS, de Jesus A, de Almeida RP, da Silva JS.

J Infect Dis. 2015 Mar 15;211(6):1015-26. doi: 10.1093/infdis/jiu531. Epub 2014 Oct 1.


Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania.

Lima-Junior DS, Costa DL, Carregaro V, Cunha LD, Silva AL, Mineo TW, Gutierrez FR, Bellio M, Bortoluci KR, Flavell RA, Bozza MT, Silva JS, Zamboni DS.

Nat Med. 2013 Jul;19(7):909-15. doi: 10.1038/nm.3221. Epub 2013 Jun 9.


Nucleosides from Phlebotomus papatasi salivary gland ameliorate murine collagen-induced arthritis by impairing dendritic cell functions.

Carregaro V, Sá-Nunes A, Cunha TM, Grespan R, Oliveira CJ, Lima-Junior DS, Costa DL, Verri WA Jr, Milanezi CM, Pham VM, Brand DD, Valenzuela JG, Silva JS, Ribeiro JM, Cunha FQ.

J Immunol. 2011 Oct 15;187(8):4347-59. doi: 10.4049/jimmunol.1003404. Epub 2011 Sep 19.


BALB/c mice infected with antimony treatment refractory isolate of Leishmania braziliensis present severe lesions due to IL-4 production.

Costa DL, Carregaro V, Lima-Júnior DS, Silva NM, Milanezi CM, Cardoso CR, Giudice Â, de Jesus AR, Carvalho EM, Almeida RP, Silva JS.

PLoS Negl Trop Dis. 2011 Mar 1;5(3):e965. doi: 10.1371/journal.pntd.0000965.

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