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Items: 1 to 50 of 312

1.

Heterotropic Modulation of Amylin Fibrillation by Small Molecules: Implications for Formulative Designs.

Sinézia C, Lima LMTR.

Protein J. 2019 Dec 5. doi: 10.1007/s10930-019-09877-w. [Epub ahead of print]

PMID:
31808036
2.

A new combination rule for Spatial Decision Support Systems for epidemiology.

de Lima LMM, de Sá LR, Dos Santos Macambira AFU, de Almeida Nogueira J, de Toledo Vianna RP, de Moraes RM.

Int J Health Geogr. 2019 Nov 9;18(1):25. doi: 10.1186/s12942-019-0187-7.

3.

Reduction of cardiac and renal dysfunction by new inhibitor of DPP4 in diabetic rats.

Alves BEO, de Alencar AKN, Gamba LER, Trachez MM, da Silva JS, Araújo JSC, Montagnoli TL, Mendes LVP, Pimentel-Coelho PM, do M N Cunha V, Mendez-Otero R, Oliveira GMM, Lima LM, Barreiro EJ, Sudo RT, Zapata-Sudo G.

Pharmacol Rep. 2019 Jul 22;71(6):1190-1200. doi: 10.1016/j.pharep.2019.07.005. [Epub ahead of print]

PMID:
31669883
4.

Treating Acute Cervical Radiodermatitis with Photobiomodulation Therapy: A Report of Two Cases.

Rocha BA, Simões A, Lima LMC, Teixeira MMS, Martinez ADS, Melo Filho MR, Horta MCR.

Photobiomodul Photomed Laser Surg. 2019 Oct 11. doi: 10.1089/photob.2019.4698. [Epub ahead of print]

PMID:
31603732
5.

Polyphenol analysis using high-resolution mass spectrometry allows differentiation of drought tolerant peanut genotypes.

Juliano FF, Alvarenga JFR, Lamuela-Raventos RM, Massarioli AP, Lima LM, Santos RC, Alencar SM.

J Sci Food Agric. 2019 Oct 10. doi: 10.1002/jsfa.10075. [Epub ahead of print]

PMID:
31602648
6.

Sustained release and pharmacologic evaluation of human glucagon-like peptide-1 and liraglutide from polymeric microparticles.

Icart LP, Souza FG Jr, Lima LMTR.

J Microencapsul. 2019 Dec;36(8):747-758. doi: 10.1080/02652048.2019.1677795. Epub 2019 Nov 12.

PMID:
31594428
7.

LASSBio-596 protects gastric mucosa against the development of ethanol-induced gastric lesions in mice.

Monteiro CES, Sousa JAO, Lima LM, Barreiro EJ, da Silva-Leite KES, de Carvalho CMM, Girão DKFB, Reis Barbosa AL, de Souza MHLP, Gomes Soares PM.

Eur J Pharmacol. 2019 Nov 15;863:172662. doi: 10.1016/j.ejphar.2019.172662. Epub 2019 Sep 17.

PMID:
31539551
8.

Direct antiviral therapy for treatment of hepatitis C: A real-world study from Brazil.

Lobato CMO, Codes L, Silva GF, Souza AFM, Coelho HSM, Pedroso MLA, Parise ER, Lima LMSTB, Borba LA, Evangelista AS, Rezende REF, Cheinquer H, Kuniyoshi ASO, Aires RS, Quintela EHD, Mendes LSC, Nascimento FCV, Medeiros Filho JEM, Ferraz MLCG, Abdala E, Bittencourt PL; Members of the Brazilian Real-Life Study about HCV treatment; Members of the Brazilian Real-Life Study about HCV treatment.

Ann Hepatol. 2019 Nov - Dec;18(6):849-854. doi: 10.1016/j.aohep.2019.08.001. Epub 2019 Aug 30.

9.

A colorimetric chemosensor for quantification of exchangeable Cu2+ in soil.

Fanna DJ, Lima LMP, Wei G, Li F, Reynolds JK.

Chemosphere. 2020 Jan;238:124664. doi: 10.1016/j.chemosphere.2019.124664. Epub 2019 Aug 24.

PMID:
31472349
10.

Ultrasensitive Colorimetric and Ratiometric Detection of Cu2+: Acid-Base Properties, Complexation, and Binding Studies.

Fanna DJ, Lima LMP, Craze AR, Trinchi A, Wuhrer R, Lindoy LF, Wei G, Reynolds JK, Li F.

ACS Omega. 2018 Sep 4;3(9):10471-10480. doi: 10.1021/acsomega.8b01483. eCollection 2018 Sep 30.

11.

Homologation: A Versatile Molecular Modification Strategy to Drug Discovery.

Lima LM, Alves MA, do Amaral DN.

Curr Top Med Chem. 2019;19(19):1734-1750. doi: 10.2174/1568026619666190808145235. Review.

PMID:
31393250
12.

T Cell Responses Induced by DNA Vaccines Based on the DENV2 E and NS1 Proteins in Mice: Importance in Protection and Immunodominant Epitope Identification.

Pinto PBA, Assis ML, Vallochi AL, Pacheco AR, Lima LM, Quaresma KRL, Pereira BAS, Costa SM, Alves AMB.

Front Immunol. 2019 Jul 3;10:1522. doi: 10.3389/fimmu.2019.01522. eCollection 2019.

13.

A Threshold-Based Decision-Support System for Fungicide Applications Provides Cost-Effective Control of Citrus Postbloom Fruit Drop.

Gama AB, Silva Junior GJ, Peres NA, Edwards Molina J, de Lima LM, Amorim L.

Plant Dis. 2019 Sep;103(9):2433-2442. doi: 10.1094/PDIS-01-19-0068-RE. Epub 2019 Jul 12.

PMID:
31306093
14.

Oxidative stress markers in cognitively intact patients with diabetic neuropathy.

Etienne I, Magalhães LVB, Cardoso SA, de Freitas RB, de Oliveira GP, Palotás A, Lima LM.

Brain Res Bull. 2019 Aug;150:196-200. doi: 10.1016/j.brainresbull.2019.06.001. Epub 2019 Jun 5.

15.

endo- versus exo-Cyclic coordination in copper complexes with methylthiazolylcarboxylate tacn derivatives.

Guillou A, Lima LMP, Esteban-Gómez D, Delgado R, Platas-Iglesias C, Patinec V, Tripier R.

Dalton Trans. 2019 Jun 28;48(24):8740-8755. doi: 10.1039/c9dt01366k. Epub 2019 May 30.

PMID:
31143891
16.

Physico-chemical stability of co-formulation of PEGylated human amylin with insulin.

Sinésia C, do Nascimento CVMF, Lacativa PGS, Lima LMTR.

Pharm Dev Technol. 2019 Oct;24(8):975-981. doi: 10.1080/10837450.2019.1621896. Epub 2019 Jun 18.

PMID:
31124388
17.

Insulin resistance underlying type 2 diabetes.

Lima LMTR.

Lancet Diabetes Endocrinol. 2019 Jun;7(6):424. doi: 10.1016/S2213-8587(19)30147-0. No abstract available.

PMID:
31103174
18.

Semicarbazone derivatives as promising therapeutic alternatives in leishmaniasis.

Cavalcanti de Queiroz A, Alves MA, Barreiro EJ, Lima LM, Alexandre-Moreira MS.

Exp Parasitol. 2019 Jun;201:57-66. doi: 10.1016/j.exppara.2019.04.003. Epub 2019 Apr 17.

PMID:
31004571
19.

BZ043, a novel long-acting amylin analog, reduces gastric emptying, food intake, glycemia and insulin requirement in streptozotocin-induced diabetic rats.

Nascimento CVMF, Sinezia C, Sisnande T, Lima LMTR, Lacativa PGS.

Peptides. 2019 Apr;114:44-49. doi: 10.1016/j.peptides.2019.04.004. Epub 2019 Apr 14.

PMID:
30995454
20.

Impact of Developmental enamel defects on quality of life in 5-year-old children.

Andrade NS, Dos Santos IT, Lima LMS, Lima CCB, Moura LFAD, Barros SSLV, Moura MS, Lima MDM.

Int J Paediatr Dent. 2019 Sep;29(5):557-565. doi: 10.1111/ipd.12498. Epub 2019 Apr 14.

PMID:
30912196
21.

Methylthiazolyl Tacn Ligands for Copper Complexation and Their Bifunctional Chelating Agent Derivatives for Bioconjugation and Copper-64 Radiolabeling: An Example with Bombesin.

Guillou A, Lima LMP, Esteban-Gómez D, Le Poul N, Bartholomä MD, Platas-Iglesias C, Delgado R, Patinec V, Tripier R.

Inorg Chem. 2019 Feb 18;58(4):2669-2685. doi: 10.1021/acs.inorgchem.8b03280. Epub 2019 Jan 28.

PMID:
30689368
22.

A novel scaffold for EGFR inhibition: Introducing N-(3-(3-phenylureido)quinoxalin-6-yl) acrylamide derivatives.

do Amaral DN, Lategahn J, Fokoue HH, da Silva EMB, Sant'Anna CMR, Rauh D, Barreiro EJ, Laufer S, Lima LM.

Sci Rep. 2019 Jan 9;9(1):14. doi: 10.1038/s41598-018-36846-7.

23.

Natural products as new antimitotic compounds for anticancer drug development.

Paier CRK, Maranhão SS, Carneiro TR, Lima LM, Rocha DD, Santos RDS, Farias KM, Moraes-Filho MO, Pessoa C.

Clinics (Sao Paulo). 2018 Dec 10;73(suppl 1):e813s. doi: 10.6061/clinics/2018/e813s. Review.

24.

Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution.

Lixa C, Mujo A, de Magalhães MTQ, Almeida FCL, Lima LMTR, Pinheiro AS.

J Biomol NMR. 2018 Dec;72(3-4):179-192. doi: 10.1007/s10858-018-0217-y. Epub 2018 Dec 8.

PMID:
30535889
25.

Monitoring asparaginase activity.

Lima LMTR, Araujo TS, Almeida FCL, Almeida MS.

Lancet Oncol. 2018 Nov;19(11):e574. doi: 10.1016/S1470-2045(18)30656-9. Epub 2018 Nov 1. No abstract available.

PMID:
30507477
26.

Biologically produced silver chloride nanoparticles from B. megaterium modulate interleukin secretion by human adipose stem cell spheroids.

Charelli LE, Müller N, Silva KR, Lima LMTR, Sant'Anna C, Baptista LS.

Cytotechnology. 2018 Dec;70(6):1655-1669. doi: 10.1007/s10616-018-0257-x. Epub 2018 Nov 1.

27.

Transgenic Nicotiana tabacum seeds expressing the Mycobacterium tuberculosis Alanine- and Proline-rich antigen.

Módolo DG, Horn CS, Soares JSM, Yunes JA, Lima LM, de Sousa SM, Menossi M.

AMB Express. 2018 Oct 31;8(1):178. doi: 10.1186/s13568-018-0708-y.

28.

Association of breast cancer with human papillomavirus (HPV) infection in Northeast Brazil: molecular evidence.

Cavalcante JR, Pinheiro LGP, Almeida PRC, Ferreira MVP, Cruz GA, Campelo TA, Silva CS, Lima LNGC, Oliveira BMK, Lima LM, Feitosa LMC, Pinheiro AC, Frota CC.

Clinics (Sao Paulo). 2018 Oct 18;73:e465. doi: 10.6061/clinics/2018/e465.

29.

Contact angle measurement of free-standing square-millimeter single-layer graphene.

Prydatko AV, Belyaeva LA, Jiang L, Lima LMC, Schneider GF.

Nat Commun. 2018 Oct 10;9(1):4185. doi: 10.1038/s41467-018-06608-0.

30.

Antinociceptive activity of ethanolic extract of Azadirachta indica A. Juss (Neem, Meliaceae) fruit through opioid, glutamatergic and acid-sensitive ion pathways in adult zebrafish (Danio rerio).

Batista FLA, Lima LMG, Abrante IA, de Araújo JIF, Batista FLA, Abrante IA, Magalhães EA, de Lima DR, Lima MDCL, do Prado BS, Moura LFWG, Guedes MIF, Ferreira MKA, de Menezes JESA, Santos SAAR, Mendes FRS, Moreira RA, Monteiro-Moreira ACO, Campos AR, Magalhães FEA.

Biomed Pharmacother. 2018 Dec;108:408-416. doi: 10.1016/j.biopha.2018.08.160. Epub 2018 Sep 17.

31.

Sexually Transmitted Infections Detected by Multiplex Real Time PCR in Asymptomatic Women and Association with Cervical Intraepithelial Neoplasia.

Lima LM, Hoelzle CR, Simões RT, Lima MIM, Fradico JRB, Mateo ECC, Zauli DAG, Melo VH.

Rev Bras Ginecol Obstet. 2018 Sep;40(9):540-546. doi: 10.1055/s-0038-1669994. Epub 2018 Sep 19.

32.

Adult Zebrafish (Danio rerio) As a Model for the Study of Corneal Antinociceptive Compounds.

Magalhães FEA, Batista FLA, Lima LMG, Abrante IA, Batista FLA, Abrante IA, de Araújo JIF, Santos SAAR, de Oliveira BA, Raposo RDS, Campos AR.

Zebrafish. 2018 Dec;15(6):566-574. doi: 10.1089/zeb.2018.1633. Epub 2018 Aug 28.

PMID:
30153094
33.

LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.

Silva JC, Oliveira Júnior RG, Silva MGE, Lavor ÉM, Soares JMD, Lima-Saraiva SRG, Diniz TC, Mendes RL, Alencar Filho EB, Barreiro EJL, Lima LM, Almeida JRGDS.

PLoS One. 2018 Jul 30;13(7):e0199009. doi: 10.1371/journal.pone.0199009. eCollection 2018.

34.

N-Acylhydrazones as drugs.

Thota S, Rodrigues DA, Pinheiro PSM, Lima LM, Fraga CAM, Barreiro EJ.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2797-2806. doi: 10.1016/j.bmcl.2018.07.015. Epub 2018 Jul 9. Review.

PMID:
30006065
35.

Prognostic factors among critically ill patients with community-acquired acute bacterial meningitis and acute kidney injury.

Parente Filho SLA, Lima LMB, Dantas GLA, Silva DA, Rolim VM, Oliveira Filho AMP, Melo ITVE, Silva Junior GBD, Daher EF.

Rev Bras Ter Intensiva. 2018 Apr-Jun;30(2):153-159. doi: 10.5935/0103-507X.20180030. Portuguese, English.

36.

Physico-chemical properties of co-formulated fast-acting insulin with pramlintide.

da Silva DC, Lima LMTR.

Int J Pharm. 2018 Aug 25;547(1-2):621-629. doi: 10.1016/j.ijpharm.2018.06.039. Epub 2018 Jun 19.

PMID:
29928940
37.

Can Bradyrhizobium strains inoculation reduce water deficit effects on peanuts?

Barbosa DD, Brito SL, Fernandes PD, Fernandes-Júnior PI, Lima LM.

World J Microbiol Biotechnol. 2018 Jun 9;34(7):87. doi: 10.1007/s11274-018-2474-z.

PMID:
29886562
38.

Synthesis, X-ray diffraction study and pharmacological evaluation of 3-amino-4-methylthiophene-2-acylcarbohydrazones.

Herrmann S, Schübel T, Costa FN, Barbosa MLC, Ferreira FF, Dias TLMF, Araújo MV, Alexandre-Moreira MS, Lima LM, Laufer S, Barreiro EJ.

An Acad Bras Cienc. 2018;90(1 Suppl 2):1073-1088. doi: 10.1590/0001-3765201820170796.

39.

A case of oncogenic osteomalacia owing to inguinal tumor.

Tonello L, Gatti AP, Neto JD, Teixeira UF, Bertozzi Goldoni M, Fontes PRO, Sampaio JA, Lima LMP, Waechter FL.

Oxf Med Case Reports. 2017 Oct 26;2017(10):omx045. doi: 10.1093/omcr/omx045. eCollection 2017 Oct.

40.

Lateral Non-covalent Clamping of Graphene at the Edges Using a Lipid Scaffold.

Lima LMC, Arjmandi-Tash H, Schneider GF.

ACS Appl Mater Interfaces. 2018 Apr 4;10(13):11328-11332. doi: 10.1021/acsami.8b00916. Epub 2018 Mar 26.

41.

Oxidative imbalance in mice intoxicated by microcystin-LR can be minimized.

Casquilho NV, Moreira-Gomes MD, Magalhães CB, Okuro RT, Ortenzi VH, Feitosa-Lima EK, Lima LM, Barreiro EJ, Soares RM, Azevedo SMFO, Valença SS, Fortunato RS, Carvalho AR, Zin WA.

Toxicon. 2018 Mar 15;144:75-82. doi: 10.1016/j.toxicon.2018.02.008. Epub 2018 Feb 16.

PMID:
29454806
42.

Use of plasma exchange in pediatric severe sepsis in children's hospitals.

Lima LM, McCracken CE, Fortenberry JD, Hebbar KB.

J Crit Care. 2018 Jun;45:114-120. doi: 10.1016/j.jcrc.2018.01.028. Epub 2018 Feb 3.

PMID:
29433093
43.

Validating a probe from GhSERK1 gene for selection of cotton genotypes with somatic embryogenic capacity.

da Cunha Soares T, da Silva CRC, Chagas Carvalho JMF, Cavalcanti JJV, de Lima LM, de Albuquerque Melo Filho P, Severino LS, Dos Santos RC.

J Biotechnol. 2018 Mar 20;270:44-50. doi: 10.1016/j.jbiotec.2018.02.002. Epub 2018 Feb 7.

PMID:
29427607
44.

The toxic nature of murine amylin and the immune responsivity of pancreatic islet to conformational antibody in mice.

Erthal LCS, Jotha-Mattos L, Lara FA, Dos Reis SA, de Oliveira Pascarelli BM, Costa CM, Souza KLA, Lima LMTR.

Mol Cell Biochem. 2018 Oct;447(1-2):1-7. doi: 10.1007/s11010-018-3288-x. Epub 2018 Jan 25.

PMID:
29372531
45.

Ultrasensitive Ethene Detector Based on a Graphene-Copper(I) Hybrid Material.

Fu W, van Dijkman TF, Lima LMC, Jiang F, Schneider GF, Bouwman E.

Nano Lett. 2017 Dec 13;17(12):7980-7988. doi: 10.1021/acs.nanolett.7b04466. Epub 2017 Dec 4.

46.

Leishmanicidal candidate LASSBio-1736, a cysteine protease inhibitor with favorable pharmacokinetics: low clearance and good distribution.

Moraes BS, Azeredo FJ, Izoton JC, Amaral M, Barreiro EJ, Freddo RJ, Dalla Costa T, Lima LM, Haas SE.

Xenobiotica. 2018 Dec;48(12):1258-1267. doi: 10.1080/00498254.2017.1405465. Epub 2017 Dec 27.

PMID:
29160126
47.

Lung and liver responses to 1- and 7-day treatments with LASSBio-596 in mice subchronically intoxicated by microcystin-LR.

Oliveira VR, Carvalho GMC, Casquilho NV, Moreira-Gomes MD, Soares RM, Azevedo SMFO, Lima LM, Barreiro EJ, Takiya CM, Zin WA.

Toxicon. 2018 Jan;141:1-8. doi: 10.1016/j.toxicon.2017.10.029. Epub 2017 Oct 31.

PMID:
29097245
48.

Intraoral stents in preventing adverse radiotherapeutic effects in lip cancer patients.

Rocha BA, Lima LMC, Paranaíba LMR, Martinez ADS, Pires MBO, de Freitas EM, Vilas Boas CV, de Melo Filho MR.

Rep Pract Oncol Radiother. 2017 Nov-Dec;22(6):450-454. doi: 10.1016/j.rpor.2017.08.003. Epub 2017 Sep 1.

49.

Polyamide-Polyamine Cryptand as Dicarboxylate Receptor: Dianion Binding Studies in the Solid State, in Solution, and in the Gas Phase.

Chakraborty S, Saha S, Lima LMP, Warzok U, Sarkar S, Akhuli B, Nandi M, Bej S, Adarsh NN, Schalley CA, Delgado R, Ghosh P.

J Org Chem. 2017 Oct 6;82(19):10007-10014. doi: 10.1021/acs.joc.7b01431. Epub 2017 Sep 12.

PMID:
28845671
50.

Discovery of naphthyl-N-acylhydrazone p38α MAPK inhibitors with in vivo anti-inflammatory and anti-TNF-α activity.

Freitas RHCN, Cordeiro NM, Carvalho PR, Alves MA, Guedes IA, Valerio TS, Dardenne LE, Lima LM, Barreiro EJ, Fernandes PD, Fraga CAM.

Chem Biol Drug Des. 2018 Feb;91(2):391-397. doi: 10.1111/cbdd.13085. Epub 2017 Sep 10.

PMID:
28815968

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