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Items: 1 to 50 of 74

1.

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.

Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburgh CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT.

Neuron. 2018 Sep 5;99(5):925-940.e7. doi: 10.1016/j.neuron.2018.07.039.

PMID:
30189209
2.

Gating Protein Transport in Solid State Nanopores by Single Molecule Recognition.

Emilsson G, Sakiyama Y, Malekian B, Xiong K, Adali-Kaya Z, Lim RYH, Dahlin AB.

ACS Cent Sci. 2018 Aug 22;4(8):1007-1014. doi: 10.1021/acscentsci.8b00268. Epub 2018 Jul 26.

3.

Structural centrosome aberrations promote non-cell-autonomous invasiveness.

Ganier O, Schnerch D, Oertle P, Lim RY, Plodinec M, Nigg EA.

EMBO J. 2018 May 2;37(9). pii: e98576. doi: 10.15252/embj.201798576. Epub 2018 Mar 22.

4.

Polymer brushes in solid-state nanopores form an impenetrable entropic barrier for proteins.

Emilsson G, Xiong K, Sakiyama Y, Malekian B, Ahlberg Gagnér V, Schoch RL, Lim RYH, Dahlin AB.

Nanoscale. 2018 Mar 8;10(10):4663-4669. doi: 10.1039/c7nr09432a.

PMID:
29468241
5.

Axonemal Lumen Dominates Cytosolic Protein Diffusion inside the Primary Cilium.

Luo W, Ruba A, Takao D, Zweifel LP, Lim RYH, Verhey KJ, Yang W.

Sci Rep. 2017 Nov 17;7(1):15793. doi: 10.1038/s41598-017-16103-z.

6.

High-Speed Atomic Force Microscopy Visualization of the Dynamics of the Multienzyme Fatty Acid Synthase.

Benning FMC, Sakiyama Y, Mazur A, Bukhari HST, Lim RYH, Maier T.

ACS Nano. 2017 Nov 28;11(11):10852-10859. doi: 10.1021/acsnano.7b04216. Epub 2017 Oct 17.

PMID:
29023094
7.

Karyopherins regulate nuclear pore complex barrier and transport function.

Kapinos LE, Huang B, Rencurel C, Lim RYH.

J Cell Biol. 2017 Nov 6;216(11):3609-3624. doi: 10.1083/jcb.201702092. Epub 2017 Sep 1.

8.

Structural dynamics of the nuclear pore complex.

Sakiyama Y, Panatala R, Lim RYH.

Semin Cell Dev Biol. 2017 Aug;68:27-33. doi: 10.1016/j.semcdb.2017.05.021. Epub 2017 Jun 1. Review.

PMID:
28579449
9.

Nucleocytoplasmic Transport: A Paradigm for Molecular Logistics in Artificial Systems.

Vujica S, Zelmer C, Panatala R, Lim RY.

Chimia (Aarau). 2016;70(6):413-7. doi: 10.2533/chimia.2016.413. Review.

PMID:
27363369
10.

Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex.

Vovk A, Gu C, Opferman MG, Kapinos LE, Lim RY, Coalson RD, Jasnow D, Zilman A.

Elife. 2016 May 20;5. pii: e10785. doi: 10.7554/eLife.10785.

11.

Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy.

Sakiyama Y, Mazur A, Kapinos LE, Lim RY.

Nat Nanotechnol. 2016 Aug;11(8):719-23. doi: 10.1038/nnano.2016.62. Epub 2016 May 2.

PMID:
27136131
12.

Association of Oesophageal Hypertension with Bradycardia Mediated Deglutition Syncope.

Lim RY, Mulcahy H, Keane D.

Ir Med J. 2015 Nov-Dec;108(10):311-2.

PMID:
26817291
13.

Helium Scanning Transmission Ion Microscopy and Electrical Characterization of Glass Nanocapillaries with Reproducible Tip Geometries.

Zweifel LP, Shorubalko I, Lim RY.

ACS Nano. 2016 Feb 23;10(2):1918-25. doi: 10.1021/acsnano.5b05754. Epub 2016 Feb 1.

PMID:
26783633
14.

How to operate a nuclear pore complex by Kap-centric control.

Lim RY, Huang B, Kapinos LE.

Nucleus. 2015;6(5):366-72. doi: 10.1080/19491034.2015.1090061. Review.

15.

Nanomechanical characterization of living mammary tissues by atomic force microscopy.

Plodinec M, Lim RY.

Methods Mol Biol. 2015;1293:231-46. doi: 10.1007/978-1-4939-2519-3_14.

PMID:
26040692
16.

Strongly stretched protein resistant poly(ethylene glycol) brushes prepared by grafting-to.

Emilsson G, Schoch RL, Feuz L, Höök F, Lim RY, Dahlin AB.

ACS Appl Mater Interfaces. 2015 Apr 15;7(14):7505-15. doi: 10.1021/acsami.5b01590. Epub 2015 Apr 3.

PMID:
25812004
17.

Correction to disordered proteinaceous machines.

Fuxreiter M, Tóth-Petróczy Á, Kraut DA, Matouschek A, Lim RY, Xue B, Kurgan L, Uversky VN.

Chem Rev. 2015 Apr 8;115(7):2780. doi: 10.1021/acs.chemrev.5b00150. Epub 2015 Mar 26. No abstract available.

18.

Promiscuous binding of Karyopherinβ1 modulates FG nucleoporin barrier function and expedites NTF2 transport kinetics.

Wagner RS, Kapinos LE, Marshall NJ, Stewart M, Lim RYH.

Biophys J. 2015 Feb 17;108(4):918-927. doi: 10.1016/j.bpj.2014.12.041.

19.

Selective transport control on molecular velcro made from intrinsically disordered proteins.

Schleicher KD, Dettmer SL, Kapinos LE, Pagliara S, Keyser UF, Jeney S, Lim RY.

Nat Nanotechnol. 2014 Jul;9(7):525-30. doi: 10.1038/nnano.2014.103. Epub 2014 Jun 15.

PMID:
24929341
20.

Karyopherin-centric control of nuclear pores based on molecular occupancy and kinetic analysis of multivalent binding with FG nucleoporins.

Kapinos LE, Schoch RL, Wagner RS, Schleicher KD, Lim RY.

Biophys J. 2014 Apr 15;106(8):1751-62. doi: 10.1016/j.bpj.2014.02.021.

21.

Disordered proteinaceous machines.

Fuxreiter M, Tóth-Petróczy Á, Kraut DA, Matouschek A, Lim RY, Xue B, Kurgan L, Uversky VN.

Chem Rev. 2014 Jul 9;114(13):6806-43. doi: 10.1021/cr4007329. Epub 2014 Apr 4. Review. No abstract available. Erratum in: Chem Rev. 2015 Apr 8;115(7):2780. Matouschek, Andreas T [corrected to Matouschek, Andreas].

22.

Oral vancomycin desensitisation to treat Clostridium difficile infection in a vancomycin allergic patient.

Mahabir S, Lim RY, Fitzpatrick F, Magee C, Keogan M.

World Allergy Organ J. 2013 Sep 30;6(1):16. doi: 10.1186/1939-4551-6-16.

23.

Woman with chest pain and shortness of breath since age 18.

Lobo R, Lim RY, Meany B, Kiernan TJ.

BMJ Case Rep. 2013 Aug 14;2013. pii: bcr2013010118. doi: 10.1136/bcr-2013-010118.

24.

The challenge of suicide prevention.

Lim RY.

Med J Aust. 2013 May 20;198(9):503-4. No abstract available.

PMID:
23682897
25.

Non-interacting molecules as innate structural probes in surface plasmon resonance.

Schoch RL, Lim RY.

Langmuir. 2013 Mar 26;29(12):4068-76. doi: 10.1021/la3049289. Epub 2013 Mar 15.

PMID:
23437874
26.

The nanomechanical signature of breast cancer.

Plodinec M, Loparic M, Monnier CA, Obermann EC, Zanetti-Dallenbach R, Oertle P, Hyotyla JT, Aebi U, Bentires-Alj M, Lim RY, Schoenenberger CA.

Nat Nanotechnol. 2012 Nov;7(11):757-65. doi: 10.1038/nnano.2012.167. Epub 2012 Oct 21.

PMID:
23085644
27.

Nuclear transport receptor binding avidity triggers a self-healing collapse transition in FG-nucleoporin molecular brushes.

Schoch RL, Kapinos LE, Lim RY.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16911-6. doi: 10.1073/pnas.1208440109. Epub 2012 Oct 4.

28.

Nanoscale topographic and biomechanical studies of the human internal limiting membrane.

Henrich PB, Monnier CA, Halfter W, Haritoglou C, Strauss RW, Lim RY, Loparic M.

Invest Ophthalmol Vis Sci. 2012 Jun 29;53(6):2561-70. doi: 10.1167/iovs.11-8502.

PMID:
22410559
29.

From structural architecture to cellular organization: celebrating the scientific contributions of Ueli Aebi on the occasion of his retirement.

Lim RY, Herrmann H.

J Struct Biol. 2012 Jan;177(1):1-2. doi: 10.1016/j.jsb.2011.12.011. Epub 2012 Jan 2. No abstract available.

PMID:
22227641
30.

Single-molecule transport across an individual biomimetic nuclear pore complex.

Kowalczyk SW, Kapinos L, Blosser TR, Magalhães T, van Nies P, Lim RY, Dekker C.

Nat Nanotechnol. 2011 Jun 19;6(7):433-8. doi: 10.1038/nnano.2011.88.

PMID:
21685911
31.

Synthetic protein targeting by the intrinsic biorecognition functionality of poly(ethylene glycol) using PEG antibodies as biohybrid molecular adaptors.

Hyotyla JT, Deng J, Lim RY.

ACS Nano. 2011 Jun 28;5(6):5180-7. doi: 10.1021/nn201327y. Epub 2011 Jun 7.

PMID:
21627081
32.

Effects of blood contamination on microtensile bond strength to dentin of three self-etch adhesives.

Chang SW, Cho BH, Lim RY, Kyung SH, Park DS, Oh TS, Yoo HM.

Oper Dent. 2010 May-Jun;35(3):330-6. doi: 10.2341/09-244-L.

PMID:
20533634
33.

Converging on the function of intrinsically disordered nucleoporins in the nuclear pore complex.

Peleg O, Lim RY.

Biol Chem. 2010 Jul;391(7):719-30. doi: 10.1515/BC.2010.092. Review.

PMID:
20482319
34.

Sensing surface PEGylation with microcantilevers.

Backmann N, Kappeler N, Braun T, Huber F, Lang HP, Gerber C, Lim RY.

Beilstein J Nanotechnol. 2010;1:3-13. doi: 10.3762/bjnano.1.2. Epub 2010 Nov 22.

35.

Interaction forces and reversible collapse of a polymer brush-gated nanopore.

Lim RY, Deng J.

ACS Nano. 2009 Oct 27;3(10):2911-8. doi: 10.1021/nn900152m.

PMID:
19728698
36.

Structural analysis of the nuclear pore complex by integrated approaches.

Elad N, Maimon T, Frenkiel-Krispin D, Lim RY, Medalia O.

Curr Opin Struct Biol. 2009 Apr;19(2):226-32. doi: 10.1016/j.sbi.2009.02.009. Epub 2009 Mar 25. Review.

PMID:
19327984
37.

Biology and biophysics of the nuclear pore complex and its components.

Lim RY, Ullman KS, Fahrenkrog B.

Int Rev Cell Mol Biol. 2008;267:299-342. doi: 10.1016/S1937-6448(08)00632-1. Review.

38.

Efficient expansion of clinical-grade human fibroblasts on microcarriers: cells suitable for ex vivo expansion of clinical-grade hESCs.

Phillips BW, Lim RY, Tan TT, Rust WL, Crook JM.

J Biotechnol. 2008 Mar 20;134(1-2):79-87. doi: 10.1016/j.jbiotec.2007.12.007. Epub 2008 Jan 8.

PMID:
18261818
39.

Towards reconciling structure and function in the nuclear pore complex.

Lim RY, Aebi U, Fahrenkrog B.

Histochem Cell Biol. 2008 Feb;129(2):105-16. doi: 10.1007/s00418-007-0371-x. Epub 2008 Jan 29. Review.

40.

Nanomechanical basis of selective gating by the nuclear pore complex.

Lim RY, Fahrenkrog B, Köser J, Schwarz-Herion K, Deng J, Aebi U.

Science. 2007 Oct 26;318(5850):640-3. Epub 2007 Oct 4.

41.

Gate-crashing the nuclear pore complex.

Lim RY.

Structure. 2007 Aug;15(8):889-91.

42.

Nanomechanical interactions of phenylalanine-glycine nucleoporins studied by single molecule force-volume spectroscopy.

Lim RY, Köser J, Huang NP, Schwarz-Herion K, Aebi U.

J Struct Biol. 2007 Aug;159(2):277-89. Epub 2007 Feb 16.

PMID:
17446086
43.

Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport.

Lim RY, Huang NP, Köser J, Deng J, Lau KH, Schwarz-Herion K, Fahrenkrog B, Aebi U.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9512-7. Epub 2006 Jun 12.

44.

The nuclear pore complex up close.

Lim RY, Fahrenkrog B.

Curr Opin Cell Biol. 2006 Jun;18(3):342-7. Epub 2006 May 2. Review.

PMID:
16631361
45.

From the trap to the basket: getting to the bottom of the nuclear pore complex.

Lim RY, Aebi U, Stoffler D.

Chromosoma. 2006 Feb;115(1):15-26. Epub 2006 Jan 10.

PMID:
16402261
46.

In silico access to the nuclear pore complex.

Lim RY, Aebi U.

Structure. 2005 Dec;13(12):1741-3. No abstract available.

47.

Discrete solvation layering in confined binary liquids.

Lim RY, O'Shea SJ.

Langmuir. 2004 Jun 8;20(12):4916-9.

PMID:
15984250
48.

Management of vagus nerve injury afer carotid endarterectomy.

AbuRahma AF, Lim RY.

Surgery. 1996 Mar;119(3):245-7.

PMID:
8619177
49.

Endoscopic CO2 laser cricopharyngeal myotomy.

Lim RY.

J Clin Laser Med Surg. 1995 Aug;13(4):241-7.

PMID:
10155059
50.

Contact Nd:YAG laser excision of rhinophyma.

Lim RY.

W V Med J. 1994 Feb;90(2):62-3.

PMID:
8165809

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