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Items: 17

1.

An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma.

Sano R, Krytska K, Larmour CE, Raman P, Martinez D, Ligon GF, Lillquist JS, Cucchi U, Orsini P, Rizzi S, Pawel BR, Alvarado D, Mossé YP.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau9732. doi: 10.1126/scitranslmed.aau9732.

PMID:
30867324
2.

ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC.

Alvarado D, Ligon GF, Lillquist JS, Seibel SB, Wallweber G, Neumeister VM, Rimm DL, McMahon G, LaVallee TM.

PLoS One. 2017 Jul 19;12(7):e0181356. doi: 10.1371/journal.pone.0181356. eCollection 2017.

3.

Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration.

Lee S, Greenlee EB, Amick JR, Ligon GF, Lillquist JS, Natoli EJ Jr, Hadari Y, Alvarado D, Schlessinger J.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13225-30. doi: 10.1073/pnas.1518361112. Epub 2015 Oct 12.

4.

Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK.

Murray PB, Lax I, Reshetnyak A, Ligon GF, Lillquist JS, Natoli EJ Jr, Shi X, Folta-Stogniew E, Gunel M, Alvarado D, Schlessinger J.

Sci Signal. 2015 Jan 20;8(360):ra6. doi: 10.1126/scisignal.2005916.

PMID:
25605972
5.

(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.

Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, Liu S, McClure LD, McPherson RK, Olson TV, Orena SJ, Parker JC, Rocke BN, Soeller WC, Soglia CB, Treadway JL, Vanvolkenburg MA, Zhao Z, Cox ED.

Bioorg Med Chem Lett. 2007 Oct 15;17(20):5638-42. Epub 2007 Aug 22.

PMID:
17822893
6.

cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization.

Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, McClure LD, McPherson RK, Orena SJ, Parker JC, Polivkova J, Qiu X, Soeller WC, Soglia CB, Treadway JL, VanVolkenburg MA, Wang H, Wilder DC, Olson TV.

J Med Chem. 2006 Jun 1;49(11):3068-76.

PMID:
16722626
7.

Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells.

Carty MD, Lillquist JS, Peshavaria M, Stein R, Soeller WC.

J Biol Chem. 1997 May 2;272(18):11986-93.

8.

Type I IL-1 receptor: ligand specific confirmation differences and the role of glycosylation in ligand binding.

Einstein R, Jackson JR, D'Alessio K, Lillquist JS, Sathe G, Porter T, Young PR.

Cytokine. 1996 Mar;8(3):206-13.

PMID:
8833035
9.

Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle.

Marshall BA, Ren JM, Johnson DW, Gibbs EM, Lillquist JS, Soeller WC, Holloszy JO, Mueckler M.

J Biol Chem. 1993 Sep 5;268(25):18442-5.

10.

Mapping of neutralizing epitopes and the receptor binding site of human interleukin 1 beta.

Simon PL, Kumar V, Lillquist JS, Bhatnagar P, Einstein R, Lee J, Porter T, Green D, Sathe G, Young PR.

J Biol Chem. 1993 May 5;268(13):9771-9.

11.

Secretion of N-glycosylated interleukin-1 beta in Saccharomyces cerevisiae using a leader peptide from Candida albicans. Effect of N-linked glycosylation on biological activity.

Livi GP, Lillquist JS, Miles LM, Ferrara A, Sathe GM, Simon PL, Meyers CA, Gorman JA, Young PR.

J Biol Chem. 1991 Aug 15;266(23):15348-55.

12.

Structure-activity studies of human IL-1 beta with mature and truncated proteins expressed in Escherichia coli.

Lillquist JS, Simon PL, Summers M, Jonak Z, Young PR.

J Immunol. 1988 Sep 15;141(6):1975-81.

PMID:
3049798
13.

Purification and characterization of human recombinant interleukin-1 beta.

Meyers CA, Johanson KO, Miles LM, McDevitt PJ, Simon PL, Webb RL, Chen MJ, Holskin BP, Lillquist JS, Young PR.

J Biol Chem. 1987 Aug 15;262(23):11176-81.

14.

Cloning of eukaryotic genes in single-strand phage vectors: the human interferon genes.

Bowden DW, Mao J, Gill T, Hsiao K, Lillquist JS, Testa D, Vovis GF.

Gene. 1984 Jan;27(1):87-99.

PMID:
6325303
15.

Growth factors adherent to cell substrate are mitogenically active in situ.

Smith JC, Singh JP, Lillquist JS, Goon DS, Stiles CD.

Nature. 1982 Mar 11;296(5853):154-6. No abstract available.

PMID:
6278315
16.
17.

Initiation of cell replication by cationic polypeptide hormones.

Scher CD, Farhi JI, Handin RI, Kaplan DR, Lillquist JS, McGovern K, Stiles CD.

Soc Gen Physiol Ser. 1980;35:39-54. No abstract available.

PMID:
7414371

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