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Analysis of HLA-G expression in renal tissue in lupus nephritis: a pilot study.

Foschi V, Bortolotti D, Doyle AF, Stratigou V, Stephens L, Trivedi P, Rinaldi R, Padovan M, Bortoluzzi A, Lightstone L, Cairns TD, Botto M, Cook TH, Rizzo R, Govoni M, Pickering MC.

Lupus. 2019 Jul 10:961203319860582. doi: 10.1177/0961203319860582. [Epub ahead of print]


Diagnostic Indicators of Superimposed Preeclampsia in Women With CKD.

Wiles K, Bramham K, Seed PT, Kurlak LO, Mistry HD, Nelson-Piercy C, Lightstone L, Chappell LC.

Kidney Int Rep. 2019 Mar 26;4(6):842-853. doi: 10.1016/j.ekir.2019.03.012. eCollection 2019 Jun.


Standardized Outcomes in Nephrology-Glomerular Disease (SONG-GD): establishing a core outcome set for trials in patients with glomerular disease.

Carter SA, Lightstone L, Cattran D, Bagga A, Barbour SJ, Barratt J, Boletis J, Caster D, Coppo R, Fervenza FC, Floege J, Hladunewich M, Hogan JJ, Kitching AR, Lafayette R, Malvar A, Radhakrishnan J, Rovin BH, Zhang H, Gutman T, Howell M, Logeman C, Shen JI, Teixeira-Pinto A, Alexander SI, Cho Y, Craig JC, Harris D, Johnson DW, Kerr PG, Ryan J, Viecelli AK, Wang AY, Wilkie M, Scholes-Robertson N, Tong A; SONG-GD Initiative.

Kidney Int. 2019 Jun;95(6):1280-1283. doi: 10.1016/j.kint.2019.01.047. No abstract available.


Serum Creatinine in Pregnancy: A Systematic Review.

Wiles K, Bramham K, Seed PT, Nelson-Piercy C, Lightstone L, Chappell LC.

Kidney Int Rep. 2018 Oct 29;4(3):408-419. doi: 10.1016/j.ekir.2018.10.015. eCollection 2019 Mar.


Glomerular membrane attack complex is not a reliable marker of ongoing C5 activation in lupus nephritis.

Wilson HR, Medjeral-Thomas NR, Gilmore AC, Trivedi P, Seyb K, Farzaneh-Far R, Gunnarsson I, Zickert A, Cairns TD, Lightstone L, Cook HT, Pickering MC.

Kidney Int. 2019 Mar;95(3):655-665. doi: 10.1016/j.kint.2018.09.027. Epub 2019 Jan 14.


Comment on: The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults: reply.

Gordon C, Amissah-Arthur MB, Gayed M, Brown S, Bruce IN, D'Cruz D, Empson B, Griffiths B, Jayne D, Khamashta M, Lightstone L, Norton P, Norton Y, Schreiber K, Isenberg D; British Society for Rheumatology Standards, Audit and Guidelines Working Group.

Rheumatology (Oxford). 2018 Aug 1;57(8):1502-1503. doi: 10.1093/rheumatology/key170. No abstract available.


Glomerular Disease in Women.

Wiles K, Lightstone L.

Kidney Int Rep. 2018 Feb 2;3(2):258-270. doi: 10.1016/j.ekir.2018.01.010. eCollection 2018 Mar. Review.


Ofatumumab for B cell depletion in patients with systemic lupus erythematosus who are allergic to rituximab.

Masoud S, McAdoo SP, Bedi R, Cairns TD, Lightstone L.

Rheumatology (Oxford). 2018 Mar 19. doi: 10.1093/rheumatology/key042. [Epub ahead of print]


Kidneys and women's health: key challenges and considerations.

Ashuntantang GE, Garovic VD, Heilberg IP, Lightstone L.

Nat Rev Nephrol. 2018 Mar;14(3):203-210. doi: 10.1038/nrneph.2017.188. Epub 2018 Jan 30. Review.


Hydroxycloroquine blood concentration in lupus nephritis: a determinant of disease outcome?

Cunha C, Alexander S, Ashby D, Lee J, Chusney G, Cairns TD, Lightstone L.

Nephrol Dial Transplant. 2018 Sep 1;33(9):1604-1610. doi: 10.1093/ndt/gfx318.


Can we manage lupus nephritis without chronic corticosteroids administration?

Lightstone L, Doria A, Wilson H, Ward FL, Larosa M, Bargman JM.

Autoimmun Rev. 2018 Jan;17(1):4-10. doi: 10.1016/j.autrev.2017.11.002. Epub 2017 Nov 3. Review.


Can we withdraw immunosuppressants in patients with lupus nephritis in remission? An expert debate.

Moroni G, Gatto M, Raffiotta F, Binda V, Frangou E, Lightstone L, Boumpas DT.

Autoimmun Rev. 2018 Jan;17(1):11-18. doi: 10.1016/j.autrev.2017.11.003. Epub 2017 Nov 3. Review.


The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults.

Gordon C, Amissah-Arthur MB, Gayed M, Brown S, Bruce IN, D'Cruz D, Empson B, Griffiths B, Jayne D, Khamashta M, Lightstone L, Norton P, Norton Y, Schreiber K, Isenberg D; British Society for Rheumatology Standards, Audit and Guidelines Working Group.

Rheumatology (Oxford). 2018 Jan 1;57(1):e1-e45. doi: 10.1093/rheumatology/kex286. No abstract available.


The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults: Executive Summary.

Gordon C, Amissah-Arthur MB, Gayed M, Brown S, Bruce IN, D'Cruz D, Empson B, Griffiths B, Jayne D, Khamashta M, Lightstone L, Norton P, Norton Y, Schreiber K, Isenberg D; British Society for Rheumatology Standards, Audit and Guidelines Working Group.

Rheumatology (Oxford). 2018 Jan 1;57(1):14-18. doi: 10.1093/rheumatology/kex291. No abstract available.


Manifestations of lupus in the kidney and how to manage them.

Wilson HR, Lightstone L.

Nephrol Dial Transplant. 2017 Oct 1;32(10):1614-1616. doi: 10.1093/ndt/gfx273. No abstract available.


Positive antineutrophil cytoplasmic antibody serology in patients with lupus nephritis is associated with distinct histopathologic features on renal biopsy.

Turner-Stokes T, Wilson HR, Morreale M, Nunes A, Cairns T, Cook HT, Pusey CD, Tarzi RM, Lightstone L.

Kidney Int. 2017 Nov;92(5):1223-1231. doi: 10.1016/j.kint.2017.04.029. Epub 2017 Jul 24.


Lupus Nephritis and Pregnancy: Concerns and Management.

Lightstone L, Hladunewich MA.

Semin Nephrol. 2017 Jul;37(4):347-353. doi: 10.1016/j.semnephrol.2017.05.006. Review.


Mycophenolate mofetil therapy in immunoglobulin A nephropathy: histological changes after treatment.

Beckwith H, Medjeral-Thomas N, Galliford J, Griffith M, Levy J, Lightstone L, Palmer A, Roufosse C, Pusey C, Cook HT, Cairns T.

Nephrol Dial Transplant. 2017 Jan 1;32(suppl_1):i123-i128. doi: 10.1093/ndt/gfw326.


Altered expression of signalling lymphocyte activation molecule receptors in T-cells from lupus nephritis patients-a potential biomarker of disease activity.

Stratigou V, Doyle AF, Carlucci F, Stephens L, Foschi V, Castelli M, McKenna N, Cook HT, Lightstone L, Cairns TD, Pickering MC, Botto M.

Rheumatology (Oxford). 2017 Jul 1;56(7):1206-1216. doi: 10.1093/rheumatology/kex078.


Pregnancy in chronic kidney disease and kidney transplantation.

Webster P, Lightstone L, McKay DB, Josephson MA.

Kidney Int. 2017 May;91(5):1047-1056. doi: 10.1016/j.kint.2016.10.045. Epub 2017 Feb 13. Review.


A complicated multisystem flare of systemic lupus erythematosus during pregnancy.

Webster P, Nelson-Piercy C, Lightstone L.

BMJ Case Rep. 2017 Feb 8;2017. pii: bcr2016217546. doi: 10.1136/bcr-2016-217546.


A Multicenter Cohort Study of Histologic Findings and Long-Term Outcomes of Kidney Disease in Women Who Have Been Pregnant.

Webster P, Webster LM, Cook HT, Horsfield C, Seed PT, Vaz R, Santos C, Lydon I, Homsy M, Lightstone L, Bramham K.

Clin J Am Soc Nephrol. 2017 Mar 7;12(3):408-416. doi: 10.2215/CJN.05610516. Epub 2016 Dec 9.


Development of a Glucocorticoid Toxicity Index (GTI) using multicriteria decision analysis.

Miloslavsky EM, Naden RP, Bijlsma JW, Brogan PA, Brown ES, Brunetta P, Buttgereit F, Choi HK, DiCaire JF, Gelfand JM, Heaney LG, Lightstone L, Lu N, Murrell DF, Petri M, Rosenbaum JT, Saag KS, Urowitz MB, Winthrop KL, Stone JH.

Ann Rheum Dis. 2017 Mar;76(3):543-546. doi: 10.1136/annrheumdis-2016-210002. Epub 2016 Jul 29.


Diagnostic and predictive biomarkers for pre-eclampsia in patients with established hypertension and chronic kidney disease.

Bramham K, Seed PT, Lightstone L, Nelson-Piercy C, Gill C, Webster P, Poston L, Chappell LC.

Kidney Int. 2016 Apr;89(4):874-85. doi: 10.1016/j.kint.2015.10.012. Epub 2016 Jan 19.


Eculizumab as rescue therapy in severe resistant lupus nephritis.

Pickering MC, Ismajli M, Condon MB, McKenna N, Hall AE, Lightstone L, Terence Cook H, Cairns TD.

Rheumatology (Oxford). 2015 Dec;54(12):2286-8. doi: 10.1093/rheumatology/kev307. Epub 2015 Aug 27. No abstract available.


The exaggerated inflammatory response in Behçet's syndrome: identification of dysfunctional post-transcriptional regulation of the IFN-γ/CXCL10 IP-10 pathway.

Ambrose N, Khan E, Ravindran R, Lightstone L, Abraham S, Botto M, Johns M, Haskard DO.

Clin Exp Immunol. 2015 Sep;181(3):427-33. doi: 10.1111/cei.12655. Epub 2015 Jul 14.


Lupus nephritis management guidelines compared.

Wilhelmus S, Bajema IM, Bertsias GK, Boumpas DT, Gordon C, Lightstone L, Tesar V, Jayne DR.

Nephrol Dial Transplant. 2016 Jun;31(6):904-13. doi: 10.1093/ndt/gfv102. Epub 2015 Apr 28. Review.


Rituximab in systemic lupus erythematosus and lupus nephritis.

Beckwith H, Lightstone L.

Nephron Clin Pract. 2014;128(3-4):250-4. doi: 10.1159/000368585. Epub 2014 Nov 29. Review.


Necrotizing and crescentic glomerulonephritis presenting with preserved renal function in patients with underlying multisystem autoimmune disease: a retrospective case series.

McAdoo SP, Tanna A, Randone O, Tam FW, Tarzi RM, Levy JB, Griffith M, Lightstone L, Cook HT, Cairns T, Pusey CD.

Rheumatology (Oxford). 2015 Jun;54(6):1025-32. doi: 10.1093/rheumatology/keu445. Epub 2014 Nov 26.


Tacrolimus is an effective treatment for lupus nephritis in pregnancy.

Webster P, Wardle A, Bramham K, Webster L, Nelson-Piercy C, Lightstone L.

Lupus. 2014 Oct;23(11):1192-6. doi: 10.1177/0961203314540353. Epub 2014 Jun 13.


Renoprotective strategies in lupus nephritis: beyond immunosuppression.

Griffin B, Lightstone L.

Lupus. 2013 Oct;22(12):1267-73. doi: 10.1177/0961203313505927. Review.


Severe pre-eclampsia and hypertensive crises.

Arulkumaran N, Lightstone L.

Best Pract Res Clin Obstet Gynaecol. 2013 Dec;27(6):877-84. doi: 10.1016/j.bpobgyn.2013.07.003. Epub 2013 Aug 17. Review.


Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids.

Condon MB, Ashby D, Pepper RJ, Cook HT, Levy JB, Griffith M, Cairns TD, Lightstone L.

Ann Rheum Dis. 2013 Aug;72(8):1280-6. doi: 10.1136/annrheumdis-2012-202844. Epub 2013 Jun 5.


Minimising steroids in lupus nephritis--will B cell depletion pave the way?

Lightstone L.

Lupus. 2013 Apr;22(4):390-9. doi: 10.1177/0961203313476155. Review.


Breastfeeding and tacrolimus: serial monitoring in breast-fed and bottle-fed infants.

Bramham K, Chusney G, Lee J, Lightstone L, Nelson-Piercy C.

Clin J Am Soc Nephrol. 2013 Apr;8(4):563-7. doi: 10.2215/CJN.06400612. Epub 2013 Jan 24.


Seasonal relapsing minimal change disease: a novel strategy for avoiding long-term immunosuppression.

Lawrence C, Cook HT, Lightstone L.

Case Rep Nephrol Urol. 2012 Jul;2(2):102-7. doi: 10.1159/000341257. Epub 2012 Jul 24.


A multi-centre qualitative study exploring the experiences of UK South Asian and white diabetic patients referred for renal care.

Wilkinson E, Randhawa G, Feehally J, Farrington K, Greenwood R, Choi P, Lightstone L.

BMC Nephrol. 2012 Nov 23;13:157. doi: 10.1186/1471-2369-13-157.


Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis.

Bertsias GK, Tektonidou M, Amoura Z, Aringer M, Bajema I, Berden JH, Boletis J, Cervera R, Dörner T, Doria A, Ferrario F, Floege J, Houssiau FA, Ioannidis JP, Isenberg DA, Kallenberg CG, Lightstone L, Marks SD, Martini A, Moroni G, Neumann I, Praga M, Schneider M, Starra A, Tesar V, Vasconcelos C, van Vollenhoven RF, Zakharova H, Haubitz M, Gordon C, Jayne D, Boumpas DT; European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association.

Ann Rheum Dis. 2012 Nov;71(11):1771-82. doi: 10.1136/annrheumdis-2012-201940. Epub 2012 Jul 31.


Pre-pregnancy counseling for women with chronic kidney disease.

Bramham K, Lightstone L.

J Nephrol. 2012 Jul-Aug;25(4):450-9. doi: 10.5301/jn.5000130. Review.


The landscape after LUNAR: rituximab's crater-filled path.

Lightstone L.

Arthritis Rheum. 2012 Apr;64(4):962-5. doi: 10.1002/art.34362. Epub 2012 Jan 9. No abstract available.


Lack of awareness of kidney complications despite familiarity with diabetes: a multi-ethnic qualitative study.

Wilkinson E, Randhawa G, Farrington K, Greenwood R, Feehally J, Choi P, Lightstone L.

J Ren Care. 2011 Mar;37(1):2-11. doi: 10.1111/j.1755-6686.2011.00199.x.


Pregnancy in pancreas-kidney transplant recipients: report of three cases and review of the literature.

Bramham K, Lightstone L, Taylor J, Hakim NS, Harding K, McCarthy A, Chowdhury P, Duncan N, Nelson-Piercy C.

Obstet Med. 2010 Jun;3(2):73-7. doi: 10.1258/om.2009.090028. Epub 2010 Jun 3.


Genetic loci influencing kidney function and chronic kidney disease.

Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale DP, Wass MN, Ahmadi KR, Bakker SJ, Beckmann J, Bilo HJ, Bochud M, Brown MJ, Caulfield MJ, Connell JM, Cook HT, Cotlarciuc I, Davey Smith G, de Silva R, Deng G, Devuyst O, Dikkeschei LD, Dimkovic N, Dockrell M, Dominiczak A, Ebrahim S, Eggermann T, Farrall M, Ferrucci L, Floege J, Forouhi NG, Gansevoort RT, Han X, Hedblad B, Homan van der Heide JJ, Hepkema BG, Hernandez-Fuentes M, Hypponen E, Johnson T, de Jong PE, Kleefstra N, Lagou V, Lapsley M, Li Y, Loos RJ, Luan J, Luttropp K, Maréchal C, Melander O, Munroe PB, Nordfors L, Parsa A, Peltonen L, Penninx BW, Perucha E, Pouta A, Prokopenko I, Roderick PJ, Ruokonen A, Samani NJ, Sanna S, Schalling M, Schlessinger D, Schlieper G, Seelen MA, Shuldiner AR, Sjögren M, Smit JH, Snieder H, Soranzo N, Spector TD, Stenvinkel P, Sternberg MJ, Swaminathan R, Tanaka T, Ubink-Veltmaat LJ, Uda M, Vollenweider P, Wallace C, Waterworth D, Zerres K, Waeber G, Wareham NJ, Maxwell PH, McCarthy MI, Jarvelin MR, Mooser V, Abecasis GR, Lightstone L, Scott J, Navis G, Elliott P, Kooner JS.

Nat Genet. 2010 May;42(5):373-5. doi: 10.1038/ng.566. Epub 2010 Apr 11.


Lupus nephritis: where are we now?

Lightstone L.

Curr Opin Rheumatol. 2010 May;22(3):252-6. doi: 10.1097/BOR.0b013e3283386512. Review.


Rituximab is an effective treatment for lupus nephritis and allows a reduction in maintenance steroids.

Pepper R, Griffith M, Kirwan C, Levy J, Taube D, Pusey C, Lightstone L, Cairns T.

Nephrol Dial Transplant. 2009 Dec;24(12):3717-23. doi: 10.1093/ndt/gfp336. Epub 2009 Jul 17.


European consensus statement on the terminology used in the management of lupus glomerulonephritis.

Gordon C, Jayne D, Pusey C, Adu D, Amoura Z, Aringer M, Ballerin J, Cervera R, Calvo-Alén J, Chizzolini C, Dayer J, Doria A, Ferrario F, Floege J, Guillevin L, Haubitz M, Hiepe F, Houssiau F, Lesavre P, Lightstone L, Meroni P, Meyer O, Moulin B, O'Reilly K, Praga M, Schulze-Koops H, Sinico R, Smith K, Tincani A, Vasconcelos C, Hughes G.

Lupus. 2009 Mar;18(3):257-63. doi: 10.1177/0961203308100481.


Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis.

Yates J, Whittington A, Mitchell P, Lechler RI, Lightstone L, Lombardi G.

Clin Exp Immunol. 2008 Jul;153(1):44-55. doi: 10.1111/j.1365-2249.2008.03665.x. Epub 2008 May 23.


A patient with suspected miscarriage is found to have hypertension, renal failure, and thrombocytopenia: case outcome.

Laing CM, Roberts R, Lightstone L, Graham A, Cook TH, Summers S, Pusey CD.

BMJ. 2007 Jul 28;335(7612):205-6; discussion 206-8. Review. No abstract available.


Urinary proteomic profiles distinguish between active and inactive lupus nephritis.

Mosley K, Tam FW, Edwards RJ, Crozier J, Pusey CD, Lightstone L.

Rheumatology (Oxford). 2006 Dec;45(12):1497-504. Epub 2006 Oct 17.


Distal renal tubular acidosis in association with HIV infection and AIDS.

Laing CM, Roberts R, Summers S, Friedland JS, Lightstone L, Unwin RJ.

Nephrol Dial Transplant. 2006 May;21(5):1420-2. Epub 2006 Jan 31. No abstract available. Erratum in: Nephrol Dial Transplant. 2006 Jul;21(7):2044. Lighstone, Liz [corrected to Lightstone, Liz].


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