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Items: 1 to 50 of 108

1.

Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease.

Guha S, Konkwo C, Lavorato M, Mathew ND, Peng M, Ostrovsky J, Kwon YJ, Polyak E, Lightfoot R, Seiler C, Xiao R, Bennett M, Zhang Z, Nakamaru-Ogiso E, Falk MJ.

Hum Mol Genet. 2019 Jun 1;28(11):1837-1852. doi: 10.1093/hmg/ddz023.

PMID:
30668749
2.

Pharmacologic modeling of primary mitochondrial respiratory chain dysfunction in zebrafish.

Byrnes J, Ganetzky R, Lightfoot R, Tzeng M, Nakamaru-Ogiso E, Seiler C, Falk MJ.

Neurochem Int. 2018 Jul;117:23-34. doi: 10.1016/j.neuint.2017.07.008. Epub 2017 Jul 18.

3.

The impact of a point-of-care testing device on CVD risk assessment completion in New Zealand primary-care practice: A cluster randomised controlled trial and qualitative investigation.

Wells S, Rafter N, Kenealy T, Herd G, Eggleton K, Lightfoot R, Arcus K, Wadham A, Jiang Y, Bullen C.

PLoS One. 2017 Apr 19;12(4):e0174504. doi: 10.1371/journal.pone.0174504. eCollection 2017.

4.

Quantity and Quality of Daily Physical Activity in Older Cardiac Patients.

Buijs DM, Ramadi A, MacDonald K, Lightfoot R, Senaratne M, Haennel RG.

Can J Cardiovasc Nurs. 2015 Summer;25(3):10-6.

PMID:
26387271
5.

Evidence of native α-synuclein conformers in the human brain.

Gould N, Mor DE, Lightfoot R, Malkus K, Giasson B, Ischiropoulos H.

J Biol Chem. 2014 Mar 14;289(11):7929-34. doi: 10.1074/jbc.C113.538249. Epub 2014 Jan 28.

6.

Enhanced lysis and accelerated establishment of viscoelastic properties of fibrin clots are associated with pulmonary embolism.

Martinez MR, Cuker A, Mills AM, Crichlow A, Lightfoot RT, Chernysh IN, Nagaswami C, Weisel JW, Ischiropoulos H.

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 1;306(5):L397-404. doi: 10.1152/ajplung.00265.2013. Epub 2014 Jan 10.

7.

Immunoglobulins against tyrosine-nitrated epitopes in coronary artery disease.

Thomson L, Tenopoulou M, Lightfoot R, Tsika E, Parastatidis I, Martinez M, Greco TM, Doulias PT, Wu Y, Tang WH, Hazen SL, Ischiropoulos H.

Circulation. 2012 Nov 13;126(20):2392-401. doi: 10.1161/CIRCULATIONAHA.112.103796. Epub 2012 Oct 18.

8.

Development of a quality of patient-health care provider communication scale from the perspective of patients with rheumatoid arthritis.

Salt E, Crofford LJ, Studts JL, Lightfoot R, Hall LA.

Chronic Illn. 2013 Jun;9(2):103-15. doi: 10.1177/1742395312455440. Epub 2012 Jul 20.

PMID:
22822176
9.

Nitrated fibrinogen is a biomarker of oxidative stress in venous thromboembolism.

Martinez M, Cuker A, Mills A, Lightfoot R, Fan Y, Tang WH, Hazen SL, Ischiropoulos H.

Free Radic Biol Med. 2012 Jul 15;53(2):230-6. doi: 10.1016/j.freeradbiomed.2012.05.004. Epub 2012 May 10.

10.

Shoulder injury related to vaccine administration (SIRVA).

Atanasoff S, Ryan T, Lightfoot R, Johann-Liang R.

Vaccine. 2010 Nov 29;28(51):8049-52. doi: 10.1016/j.vaccine.2010.10.005. Epub 2010 Oct 16.

PMID:
20955829
11.

Opposing regulation of human alveolar type II cell differentiation by nitric oxide and hyperoxia.

Johnston LC, Gonzales LW, Lightfoot RT, Guttentag SH, Ischiropoulos H.

Pediatr Res. 2010 May;67(5):521-5. doi: 10.1203/PDR.0b013e3181d4f20f.

12.

Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans.

Dingley S, Polyak E, Lightfoot R, Ostrovsky J, Rao M, Greco T, Ischiropoulos H, Falk MJ.

Mitochondrion. 2010 Mar;10(2):125-36. doi: 10.1016/j.mito.2009.11.003. Epub 2009 Nov 10.

13.

Predicting future human and environmental health challenges: the Health and Environmental Sciences Institute's scientific mapping exercise.

Smith LL, Brent RL, Cohen SM, Doerrer NG, Goodman JI, Greim H, Holsapple MP, Lightfoot RM.

Crit Rev Toxicol. 2008;38(10):817-45. doi: 10.1080/10408440802486378 . Review.

PMID:
18853291
14.

Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF in rhesus monkeys.

Hovland DN Jr, Boyd RB, Butt MT, Engelhardt JA, Moxness MS, Ma MH, Emery MG, Ernst NB, Reed RP, Zeller JR, Gash DM, Masterman DM, Potter BM, Cosenza ME, Lightfoot RM.

Toxicol Pathol. 2007 Dec;35(7):1013-29.

PMID:
18098052
15.

Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF) in rhesus monkeys.

Hovland DN Jr, Boyd RB, Butt MT, Engelhardt JA, Moxness MS, Ma MH, Emery MG, Ernst NB, Reed RP, Zeller JR, Gash DM, Masterman DM, Potter BM, Cosenza ME, Lightfoot RM.

Toxicol Pathol. 2007 Aug;35(5):676-92.

PMID:
17763282
16.

Subcellular localization of tyrosine-nitrated proteins is dictated by reactive oxygen species generating enzymes and by proximity to nitric oxide synthase.

Heijnen HF, van Donselaar E, Slot JW, Fries DM, Blachard-Fillion B, Hodara R, Lightfoot R, Polydoro M, Spielberg D, Thomson L, Regan EA, Crapo J, Ischiropoulos H.

Free Radic Biol Med. 2006 Jun 1;40(11):1903-13. Epub 2005 Nov 15.

PMID:
16716892
17.

Autologous apoptotic cell engulfment stimulates chemokine secretion by vascular smooth muscle cells.

Fries DM, Lightfoot R, Koval M, Ischiropoulos H.

Am J Pathol. 2005 Aug;167(2):345-53.

18.

5-Hydroxytryptamine (5HT) receptors in the heart valves of cynomolgus monkeys and Sprague-Dawley rats.

Elangbam CS, Lightfoot RM, Yoon LW, Creech DR, Geske RS, Crumbley CW, Gates LD, Wall HG.

J Histochem Cytochem. 2005 May;53(5):671-7.

PMID:
15872060
19.

Airway management is a crucial area of critical care practice.

Blevin AE, Lightfoot RA, Lim MS.

Crit Care Med. 2004 Sep;32(9):1984-5. No abstract available.

PMID:
15343051
20.

Oxygen tension and inhaled nitric oxide modulate pulmonary levels of S-nitrosocysteine and 3-nitrotyrosine in rats.

Lorch SA, Munson D, Lightfoot RT, Ischiropoulos H.

Pediatr Res. 2004 Sep;56(3):345-52. Epub 2004 Jul 7.

PMID:
15240867
21.

A newly identified role for superoxide in inflammatory pain.

Wang ZQ, Porreca F, Cuzzocrea S, Galen K, Lightfoot R, Masini E, Muscoli C, Mollace V, Ndengele M, Ischiropoulos H, Salvemini D.

J Pharmacol Exp Ther. 2004 Jun;309(3):869-78. Epub 2004 Feb 26.

PMID:
14988418
22.

Nitration of tau protein is linked to neurodegeneration in tauopathies.

Horiguchi T, Uryu K, Giasson BI, Ischiropoulos H, LightFoot R, Bellmann C, Richter-Landsberg C, Lee VM, Trojanowski JQ.

Am J Pathol. 2003 Sep;163(3):1021-31. Erratum in: Am J Pathol. 2003 Dec;163(6):2645.

23.

Transient injury to rat lung mitochondrial DNA after exposure to hyperoxia and inhaled nitric oxide.

Lightfoot RT, Khov S, Ischiropoulos H.

Am J Physiol Lung Cell Mol Physiol. 2004 Jan;286(1):L23-9. Epub 2003 Feb 7.

24.

Endocardial myxomatous change in Harlan Sprague-Dawley rats (Hsd:S-D) and CD-1 mice: its microscopic resemblance to drug-induced valvulopathy in humans.

Elangbam CS, Colman KA, Lightfoot RM, Tyler RD, Wall HG.

Toxicol Pathol. 2002 Jul-Aug;30(4):483-91.

PMID:
12187939
25.

Vascular effects of GI262570X (PPAR-gamma agonist) in the brown adipose tissue of Han Wistar rats: a review of 1-month, 13-week, 27-week and 2-year oral toxicity studies.

Elangbam CS, Brodie TA, Brown HR, Nold JB, Raczniak TJ, Tyler RD, Lightfoot RM, Wall HG.

Toxicol Pathol. 2002 Jul-Aug;30(4):420-6.

PMID:
12187934
26.

Detection of peroxynitrite-induced protein and DNA modifications.

Lorch S, Lightfoot R, Ohshima H, Virág L, Chen Q, Hertkorn C, Weiss M, Souza J, Ischiropoulos H, Yermilov V, Pignatelli B, Masuda M, Szabó C.

Methods Mol Biol. 2002;196:247-75. No abstract available.

PMID:
12152205
27.

Reactive nitrogen species and proteins: biological significance and clinical relevance.

Souza JM, Chen Q, Blanchard-Fillion B, Lorch SA, Hertkorn C, Lightfoot R, Weisse M, Friel T, Paxinou E, Themistocleous M, Chov S, Ischiropoulos H.

Adv Exp Med Biol. 2001;500:169-74. Review. No abstract available.

PMID:
11764931
28.

Peroxisome proliferator-activated receptors in atherosclerosis and inflammation--an update.

Elangbam CS, Tyler RD, Lightfoot RM.

Toxicol Pathol. 2001 Mar-Apr;29(2):224-31. Review.

PMID:
11421489
29.

Oxygen-insensitive nitroreductases of Escherichia coli do not reduce 3-nitrotyrosine.

Lightfoot RT, Shuman D, Ischiropoulos H.

Free Radic Biol Med. 2000 Apr 1;28(7):1132-6.

PMID:
10832075
30.

Hepatocyte growth factor induces tubulogenesis of primary renal proximal tubular epithelial cells.

Bowes RC 3rd, Lightfoot RT, Van De Water B, Stevens JL.

J Cell Physiol. 1999 Jul;180(1):81-90.

PMID:
10362020
31.

Use of Ca2+ modulation to evaluate biliary excretion in sandwich-cultured rat hepatocytes.

Liu X, LeCluyse EL, Brouwer KR, Lightfoot RM, Lee JI, Brouwer KL.

J Pharmacol Exp Ther. 1999 Jun;289(3):1592-9.

PMID:
10336557
32.

The RXR agonist LG100268 causes hepatomegaly, improves glycaemic control and decreases cardiovascular risk and cachexia in diabetic mice suffering from pancreatic beta-cell dysfunction.

Lenhard JM, Lancaster ME, Paulik MA, Weiel JE, Binz JG, Sundseth SS, Gaskill BA, Lightfoot RM, Brown HR.

Diabetologia. 1999 May;42(5):545-54.

PMID:
10333046
33.

Practice nurses in the Waikato, 1991-1992, I: Occupational profile.

Lightfoot R, Davis P, Finn E, Lay-Yee R, Gribben B, McAvoy B.

N Z Med J. 1999 Feb 12;112(1081):26-8.

PMID:
10078210
34.

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum.

Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL, Ron D.

Genes Dev. 1998 Apr 1;12(7):982-95.

35.

Test-treatment strategies for patients suspected of having Lyme disease: a cost-effectiveness analysis.

Nichol G, Dennis DT, Steere AC, Lightfoot R, Wells G, Shea B, Tugwell P.

Ann Intern Med. 1998 Jan 1;128(1):37-48.

PMID:
9424980
36.

Laboratory evaluation in the diagnosis of Lyme disease.

Tugwell P, Dennis DT, Weinstein A, Wells G, Shea B, Nichol G, Hayward R, Lightfoot R, Baker P, Steere AC.

Ann Intern Med. 1997 Dec 15;127(12):1109-23.

PMID:
9412316
37.

Cost effective use of laboratory tests in rheumatology.

Lightfoot RW Jr.

Bull Rheum Dis. 1997 Oct;46(6):1-3. No abstract available.

PMID:
9336998
39.
40.

Retinal pigment epithelial dystrophy in Briard dogs.

Lightfoot RM, Cabral L, Gooch L, Bedford PG, Boulton ME.

Res Vet Sci. 1996 Jan;60(1):17-23.

PMID:
8745249
41.

Double-blind, placebo-controlled multicenter trial using chimeric monoclonal anti-CD4 antibody, cM-T412, in rheumatoid arthritis patients receiving concomitant methotrexate.

Moreland LW, Pratt PW, Mayes MD, Postlethwaite A, Weisman MH, Schnitzer T, Lightfoot R, Calabrese L, Zelinger DJ, Woody JN, et al.

Arthritis Rheum. 1995 Nov;38(11):1581-8.

PMID:
7488278
42.

American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis.

Felson DT, Anderson JJ, Boers M, Bombardier C, Furst D, Goldsmith C, Katz LM, Lightfoot R Jr, Paulus H, Strand V, et al.

Arthritis Rheum. 1995 Jun;38(6):727-35.

PMID:
7779114
43.

Genes required for cellulose synthesis in Agrobacterium tumefaciens.

Matthysse AG, White S, Lightfoot R.

J Bacteriol. 1995 Feb;177(4):1069-75.

44.

Methotrexate for rheumatoid arthritis. Suggested guidelines for monitoring liver toxicity. American College of Rheumatology.

Kremer JM, Alarcón GS, Lightfoot RW Jr, Willkens RF, Furst DE, Williams HJ, Dent PB, Weinblatt ME.

Arthritis Rheum. 1994 Mar;37(3):316-28.

PMID:
8129787
46.

Empiric parenteral antibiotic treatment of patients with fibromyalgia and fatigue and a positive serologic result for Lyme disease. A cost-effectiveness analysis.

Lightfoot RW Jr, Luft BJ, Rahn DW, Steere AC, Sigal LH, Zoschke DC, Gardner P, Britton MC, Kaufman RL.

Ann Intern Med. 1993 Sep 15;119(6):503-9.

PMID:
8357117
47.

The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials. The Committee on Outcome Measures in Rheumatoid Arthritis Clinical Trials.

Felson DT, Anderson JJ, Boers M, Bombardier C, Chernoff M, Fried B, Furst D, Goldsmith C, Kieszak S, Lightfoot R, et al.

Arthritis Rheum. 1993 Jun;36(6):729-40.

PMID:
8507213
48.

Palpable purpura: identifying the cause.

Lightfoot RW.

Hosp Pract (Off Ed). 1992 Dec 15;27(12):39-47. No abstract available.

PMID:
1452604
49.

Relevance of outcomes research to the practice of rheumatology.

Lightfoot RW Jr.

Bull Rheum Dis. 1992;41(8):1-3. No abstract available.

PMID:
1472958
50.

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