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Items: 3


The burden of trisomy 21 disrupts the proteostasis network in Down syndrome.

Aivazidis S, Coughlan CM, Rauniyar AK, Jiang H, Liggett LA, Maclean KN, Roede JR.

PLoS One. 2017 Apr 21;12(4):e0176307. doi: 10.1371/journal.pone.0176307. eCollection 2017.


Changing mutational and adaptive landscapes and the genesis of cancer.

Liggett LA, DeGregori J.

Biochim Biophys Acta Rev Cancer. 2017 Apr;1867(2):84-94. doi: 10.1016/j.bbcan.2017.01.005. Epub 2017 Feb 4. Review.


Trisomy 21 consistently activates the interferon response.

Sullivan KD, Lewis HC, Hill AA, Pandey A, Jackson LP, Cabral JM, Smith KP, Liggett LA, Gomez EB, Galbraith MD, DeGregori J, Espinosa JM.

Elife. 2016 Jul 29;5. pii: e16220. doi: 10.7554/eLife.16220.

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