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Items: 1 to 50 of 88

1.

Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1.

Traczyk A, Liew CW, Gill DJ, Rhodes D.

Nucleic Acids Res. 2020 Mar 18. pii: gkaa171. doi: 10.1093/nar/gkaa171. [Epub ahead of print]

PMID:
32187364
2.

Targeted lipidomics and transcriptomics profiling reveal the heterogeneity of visceral and subcutaneous white adipose tissue.

Hou B, Zhao Y, He P, Xu C, Ma P, Lam SM, Li B, Gil V, Shui G, Qiang G, Liew CW, Du G.

Life Sci. 2020 Mar 15;245:117352. doi: 10.1016/j.lfs.2020.117352. Epub 2020 Jan 29.

PMID:
32006527
3.

Sphingosine-1-Phosphate Receptor Modulator, FTY720, Improves Diastolic Dysfunction and Partially Reverses Atrial Remodeling in a Tm-E180G Mouse Model Linked to Hypertrophic Cardiomyopathy.

Ryba DM, Warren CM, Karam CN, Davis RT 3rd, Chowdhury SAK, Alvarez MG, McCann M, Liew CW, Wieczorek DF, Varga P, Solaro RJ, Wolska BM.

Circ Heart Fail. 2019 Nov;12(11):e005835. doi: 10.1161/CIRCHEARTFAILURE.118.005835. Epub 2019 Nov 5.

PMID:
31684756
4.

Lipid Profiling Reveals Browning Heterogeneity of White Adipose Tissue by Β3-Adrenergic Stimulation.

He P, Hou B, Li Y, Xu C, Ma P, Lam SM, Gil V, Yang X, Yang X, Zhang L, Shui G, Song J, Qiang G, Liew CW, Du G.

Biomolecules. 2019 Sep 3;9(9). pii: E444. doi: 10.3390/biom9090444.

5.

Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa.

Jaroensuk J, Wong YH, Zhong W, Liew CW, Maenpuen S, Sahili AE, Atichartpongkul S, Chionh YH, Nah Q, Thongdee N, McBee ME, Prestwich EG, DeMott MS, Chaiyen P, Mongkolsuk S, Dedon PC, Lescar J, Fuangthong M.

RNA. 2019 Nov;25(11):1481-1496. doi: 10.1261/rna.066746.118. Epub 2019 Aug 9.

PMID:
31399541
6.

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01.

Gu Y, Wong YH, Liew CW, Chan CEZ, Murali TM, Yap J, Too CT, Purushotorman K, Hamidinia M, El Sahili A, Goh ATH, Teo RZC, Wood KJ, Hanson BJ, Gascoigne NRJ, Lescar J, Vathsala A, MacAry PA.

Nat Commun. 2019 Feb 21;10(1):893. doi: 10.1038/s41467-019-08790-1.

7.

Forkhead box protein O1 (FoxO1) regulates hepatic serine protease inhibitor B1 (serpinB1) expression in a non-cell-autonomous fashion.

El Ouaamari A, O-Sullivan I, Shirakawa J, Basile G, Zhang W, Roger S, Thomou T, Xu S, Qiang G, Liew CW, Kulkarni RN, Unterman TG.

J Biol Chem. 2019 Jan 18;294(3):1059-1069. doi: 10.1074/jbc.RA118.006031. Epub 2018 Nov 20.

8.

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513.

Wong YH, Kumar A, Liew CW, Tharakaraman K, Srinivasaraghavan K, Sasisekharan R, Verma C, Lescar J.

Sci Rep. 2018 May 31;8(1):8449. doi: 10.1038/s41598-018-26800-y.

9.

EMC10 governs male fertility via maintaining sperm ion balance.

Zhou Y, Wu F, Zhang M, Xiong Z, Yin Q, Ru Y, Shi H, Li J, Mao S, Li Y, Cao X, Hu R, Liew CW, Ding Q, Wang X, Zhang Y.

J Mol Cell Biol. 2018 Dec 1;10(6):503-514. doi: 10.1093/jmcb/mjy024.

PMID:
29659949
10.

A computational approach to unraveling TLR signaling in murine mammary carcinoma.

Liew CW, Phuong T, Jones CB, Evans S, Hoot J, Weedling K, Ingram D, Nganga S, Kurt RA.

Comput Biol Med. 2018 Feb 1;93:56-65. doi: 10.1016/j.compbiomed.2017.12.013. Epub 2017 Dec 18.

PMID:
29277001
11.

Solution structure analysis of the periplasmic region of bacterial flagellar motor stators by small angle X-ray scattering.

Liew CW, Hynson RM, Ganuelas LA, Shah-Mohammadi N, Duff AP, Kojima S, Homma M, Lee LK.

Biochem Biophys Res Commun. 2018 Jan 8;495(2):1614-1619. doi: 10.1016/j.bbrc.2017.11.194. Epub 2017 Dec 2.

PMID:
29197577
12.

Mapping brown adipose tissue based on fat water fraction provided by Z-spectral imaging.

Scotti A, Tain RW, Li W, Gil V, Liew CW, Cai K.

J Magn Reson Imaging. 2018 Jun;47(6):1527-1533. doi: 10.1002/jmri.25890. Epub 2017 Nov 17.

13.

Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.

Liu C, Liew CW, Wong YH, Tan ST, Poh WH, Manimekalai MSS, Rajan S, Xin L, Liang ZX, Grüber G, Rice SA, Lescar J.

J Bacteriol. 2018 Jan 10;200(3). pii: e00515-17. doi: 10.1128/JB.00515-17. Print 2018 Feb 1.

14.

GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice.

Kawamori D, Shirakawa J, Liew CW, Hu J, Morioka T, Duttaroy A, Burkey B, Kulkarni RN.

Diabetologia. 2017 Aug;60(8):1442-1453. doi: 10.1007/s00125-017-4303-6. Epub 2017 May 20.

15.

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction.

Qi W, Keenan HA, Li Q, Ishikado A, Kannt A, Sadowski T, Yorek MA, Wu IH, Lockhart S, Coppey LJ, Pfenninger A, Liew CW, Qiang G, Burkart AM, Hastings S, Pober D, Cahill C, Niewczas MA, Israelsen WJ, Tinsley L, Stillman IE, Amenta PS, Feener EP, Vander Heiden MG, Stanton RC, King GL.

Nat Med. 2017 Jun;23(6):753-762. doi: 10.1038/nm.4328. Epub 2017 Apr 24.

16.

Multiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy.

Liew CW, Xu S, Wang X, McCann M, Whang Kong H, Carley AC, Pang J, Fantuzzi G, O'Donnell JM, Lewandowski ED.

Circ Heart Fail. 2017 Apr;10(4). pii: e003864. doi: 10.1161/CIRCHEARTFAILURE.117.003864.

17.

Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.

Qiang G, Whang Kong H, Gil V, Liew CW.

Sci Rep. 2017 Jan 9;7:40215. doi: 10.1038/srep40215.

18.

SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetes.

Qi W, Li Q, Liew CW, Rask-Madsen C, Lockhart SM, Rasmussen LM, Xia Y, Wang X, Khamaisi M, Croce K, King GL.

Diabetologia. 2017 Mar;60(3):585-596. doi: 10.1007/s00125-016-4159-1. Epub 2016 Dec 9.

19.

Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa.

Jaroensuk J, Atichartpongkul S, Chionh YH, Wong YH, Liew CW, McBee ME, Thongdee N, Prestwich EG, DeMott MS, Mongkolsuk S, Dedon PC, Lescar J, Fuangthong M.

Nucleic Acids Res. 2016 Dec 15;44(22):10834-10848. Epub 2016 Sep 28.

20.

Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation.

Qiang G, Whang Kong H, Xu S, Pham HA, Parlee SD, Burr AA, Gil V, Pang J, Hughes A, Gu X, Fantuzzi G, MacDougald OA, Liew CW.

Mol Metab. 2016 May 14;5(7):480-490. doi: 10.1016/j.molmet.2016.05.005. eCollection 2016 Jul.

21.

Poly(Acrylic acid)⁻Based Hybrid Inorganic⁻Organic Electrolytes Membrane for Electrical Double Layer Capacitors Application.

Liew CW, Ng HM, Numan A, Ramesh S.

Polymers (Basel). 2016 May 18;8(5). pii: E179. doi: 10.3390/polym8050179.

22.

The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation.

Qiang G, Kong HW, Fang D, McCann M, Yang X, Du G, Blüher M, Zhu J, Liew CW.

Nat Commun. 2016 Apr 25;7:11378. doi: 10.1038/ncomms11378.

23.

The Hypoglycemic Phenotype Is Islet Cell-Autonomous in Short-Chain Hydroxyacyl-CoA Dehydrogenase-Deficient Mice.

Molven A, Hollister-Lock J, Hu J, Martinez R, Njølstad PR, Liew CW, Weir G, Kulkarni RN.

Diabetes. 2016 Jun;65(6):1672-8. doi: 10.2337/db15-1475. Epub 2016 Mar 7.

24.

Domain-swap polymerization drives the self-assembly of the bacterial flagellar motor.

Baker MA, Hynson RM, Ganuelas LA, Mohammadi NS, Liew CW, Rey AA, Duff AP, Whitten AE, Jeffries CM, Delalez NJ, Morimoto YV, Stock D, Armitage JP, Turberfield AJ, Namba K, Berry RM, Lee LK.

Nat Struct Mol Biol. 2016 Mar;23(3):197-203. doi: 10.1038/nsmb.3172. Epub 2016 Feb 8.

PMID:
26854663
25.

SerpinB1 Promotes Pancreatic β Cell Proliferation.

El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN.

Cell Metab. 2016 Jan 12;23(1):194-205. doi: 10.1016/j.cmet.2015.12.001. Epub 2015 Dec 15.

26.

Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.

Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, Liew CW, Clauss TR, Valdez I, El Ouaamari A, Dirice E, Takatani T, Keenan HA, Smith RD, Church G, Weiss R, Wagers AJ, Qian WJ, King GL, Kulkarni RN.

Cell Metab. 2015 Aug 4;22(2):239-52. doi: 10.1016/j.cmet.2015.07.015.

27.

Erratum: FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.

O-Sullivan I, Zhang W, Wasserman DH, Liew CW, Liu J, Paik J, DePinho RA, Stolz DB, Kahn CR, Schwartz MW, Unterman TG.

Nat Commun. 2015 Jul 24;6:7861. doi: 10.1038/ncomms8861. No abstract available.

PMID:
26206703
28.

Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope.

Robinson LN, Tharakaraman K, Rowley KJ, Costa VV, Chan KR, Wong YH, Ong LC, Tan HC, Koch T, Cain D, Kirloskar R, Viswanathan K, Liew CW, Tissire H, Ramakrishnan B, Myette JR, Babcock GJ, Sasisekharan V, Alonso S, Chen J, Lescar J, Shriver Z, Ooi EE, Sasisekharan R.

Cell. 2015 Jul 30;162(3):493-504. doi: 10.1016/j.cell.2015.06.057. Epub 2015 Jul 16.

29.

Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics.

El Ouaamari A, Zhou JY, Liew CW, Shirakawa J, Dirice E, Gedeon N, Kahraman S, De Jesus DF, Bhatt S, Kim JS, Clauss TR, Camp DG 2nd, Smith RD, Qian WJ, Kulkarni RN.

J Proteome Res. 2015 Aug 7;14(8):3111-3122. doi: 10.1021/acs.jproteome.5b00587. Epub 2015 Jul 30.

30.

FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.

O-Sullivan I, Zhang W, Wasserman DH, Liew CW, Liu J, Paik J, DePinho RA, Stolz DB, Kahn CR, Schwartz MW, Unterman TG.

Nat Commun. 2015 May 12;6:7079. doi: 10.1038/ncomms8079. Erratum in: Nat Commun. 2015;6:7861.

31.

Electrical, structural, thermal and electrochemical properties of corn starch-based biopolymer electrolytes.

Liew CW, Ramesh S.

Carbohydr Polym. 2015 Jun 25;124:222-8. doi: 10.1016/j.carbpol.2015.02.024. Epub 2015 Feb 21.

PMID:
25839815
32.

Structure of a diguanylate cyclase from Thermotoga maritima: insights into activation, feedback inhibition and thermostability.

Deepthi A, Liew CW, Liang ZX, Swaminathan K, Lescar J.

PLoS One. 2014 Oct 31;9(10):e110912. doi: 10.1371/journal.pone.0110912. eCollection 2014.

33.

Rheological studies of PMMA-PVC based polymer blend electrolytes with LiTFSI as doping salt.

Liew CW, Durairaj R, Ramesh S.

PLoS One. 2014 Jul 22;9(7):e102815. doi: 10.1371/journal.pone.0102815. eCollection 2014.

34.

Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells.

Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2319-28. doi: 10.1073/pnas.1323066111. Epub 2014 May 19.

35.

Comparing Triflate and Hexafluorophosphate Anions of Ionic Liquids in Polymer Electrolytes for Supercapacitor Applications.

Liew CW, Ramesh S.

Materials (Basel). 2014 May 21;7(5):4019-4033. doi: 10.3390/ma7054019.

36.

The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.

Kilic G, Alvarez-Mercado AI, Zarrouki B, Opland D, Liew CW, Alonso LC, Myers MG Jr, Jonas JC, Poitout V, Kulkarni RN, Mauvais-Jarvis F.

PLoS One. 2014 Feb 3;9(2):e87941. doi: 10.1371/journal.pone.0087941. eCollection 2014.

37.

Computational and mathematical modeling of the effects of tailbeat frequency and flexural stiffness in swimming fish.

Root RG, Liew CW.

Zoology (Jena). 2014 Feb;117(1):81-5. doi: 10.1016/j.zool.2013.11.003. Epub 2013 Dec 25.

PMID:
24439761
38.

p85α deficiency protects β-cells from endoplasmic reticulum stress-induced apoptosis.

Winnay JN, Dirice E, Liew CW, Kulkarni RN, Kahn CR.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1192-7. doi: 10.1073/pnas.1322564111. Epub 2014 Jan 6.

39.

The prevalence and predictors of active brown adipose tissue in Chinese adults.

Zhang Z, Cypess AM, Miao Q, Ye H, Liew CW, Zhang Q, Xue R, Zhang S, Zuo C, Xu Z, Tang Q, Hu R, Guan Y, Li Y.

Eur J Endocrinol. 2014 Feb 4;170(3):359-66. doi: 10.1530/EJE-13-0712. Print 2014 Mar.

40.

A crystal structure of the dengue virus non-structural protein 5 (NS5) polymerase delineates interdomain amino acid residues that enhance its thermostability and de novo initiation activities.

Lim SP, Koh JH, Seh CC, Liew CW, Davidson AD, Chua LS, Chandrasekaran R, Cornvik TC, Shi PY, Lescar J.

J Biol Chem. 2013 Oct 25;288(43):31105-14. doi: 10.1074/jbc.M113.508606. Epub 2013 Sep 11.

41.

Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young).

Ræder H, Vesterhus M, El Ouaamari A, Paulo JA, McAllister FE, Liew CW, Hu J, Kawamori D, Molven A, Gygi SP, Njølstad PR, Kahn CR, Kulkarni RN.

PLoS One. 2013;8(4):e60229. doi: 10.1371/journal.pone.0060229. Epub 2013 Apr 2.

42.

Solution structure of the PAS domain of a thermophilic YybT protein homolog reveals a potential ligand-binding site.

Tan E, Rao F, Pasunooti S, Pham TH, Soehano I, Turner MS, Liew CW, Lescar J, Pervushin K, Liang ZX.

J Biol Chem. 2013 Apr 26;288(17):11949-59. doi: 10.1074/jbc.M112.437764. Epub 2013 Mar 15.

43.

X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function.

Akiyama M, Liew CW, Lu S, Hu J, Martinez R, Hambro B, Kennedy RT, Kulkarni RN.

Diabetes. 2013 Jul;62(7):2439-49. doi: 10.2337/db12-1747. Epub 2013 Mar 14.

44.

Conformational flexibility of the Dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor.

Noble CG, Lim SP, Chen YL, Liew CW, Yap L, Lescar J, Shi PY.

J Virol. 2013 May;87(9):5291-5. doi: 10.1128/JVI.00045-13. Epub 2013 Feb 13.

45.

Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states.

El Ouaamari A, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qian WJ, Wagers AJ, Kulkarni RN.

Cell Rep. 2013 Feb 21;3(2):401-10. doi: 10.1016/j.celrep.2013.01.007. Epub 2013 Jan 31. Erratum in: Cell Rep. 2013 Mar 28;3(3):969.

46.

Structural basis of the interaction of the breast cancer oncogene LMO4 with the tumour suppressor CtIP/RBBP8.

Stokes PH, Liew CW, Kwan AH, Foo P, Barker HE, Djamirze A, O'Reilly V, Visvader JE, Mackay JP, Matthews JM.

J Mol Biol. 2013 Apr 12;425(7):1101-10. doi: 10.1016/j.jmb.2013.01.017. Epub 2013 Jan 23.

PMID:
23353824
47.

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.

Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng YH, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Blüher M, Hsu SI, Kulkarni RN.

Nat Med. 2013 Feb;19(2):217-26. doi: 10.1038/nm.3056. Epub 2013 Jan 6.

48.

Increasing glucose 6-phosphate dehydrogenase activity restores redox balance in vascular endothelial cells exposed to high glucose.

Zhang Z, Yang Z, Zhu B, Hu J, Liew CW, Zhang Y, Leopold JA, Handy DE, Loscalzo J, Stanton RC.

PLoS One. 2012;7(11):e49128. doi: 10.1371/journal.pone.0049128. Epub 2012 Nov 19.

49.

Structure of human Rack1 protein at a resolution of 2.45 Å.

Ruiz Carrillo D, Chandrasekaran R, Nilsson M, Cornvik T, Liew CW, Tan SM, Lescar J.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):867-72. doi: 10.1107/S1744309112027480. Epub 2012 Jul 26.

50.

A new measure based on degree distribution that links information theory and network graph analysis.

Hadley MW, McGranaghan MF, Willey A, Liew CW, Reynolds ER.

Neural Syst Circuits. 2012 Jun 24;2(1):7.

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