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Items: 12


Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response.

Rawlinson SM, Zhao T, Rozario AM, Rootes CL, McMillan PJ, Purcell AW, Woon A, Marsh GA, Lieu KG, Wang LF, Netter HJ, Bell TDM, Stewart CR, Moseley GW.

Nat Commun. 2018 Aug 3;9(1):3057. doi: 10.1038/s41467-018-05354-7.


Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.

Atkinson SC, Audsley MD, Lieu KG, Marsh GA, Thomas DR, Heaton SM, Paxman JJ, Wagstaff KM, Buckle AM, Moseley GW, Jans DA, Borg NA.

Sci Rep. 2018 Jan 10;8(1):358. doi: 10.1038/s41598-017-18742-8.


Nuclear localization and secretion competence are conserved among henipavirus matrix proteins.

McLinton EC, Wagstaff KM, Lee A, Moseley GW, Marsh GA, Wang LF, Jans DA, Lieu KG, Netter HJ.

J Gen Virol. 2017 Apr;98(4):563-576. doi: 10.1099/jgv.0.000703. Epub 2017 Apr 14.


Interactome of the inhibitory isoform of the nuclear transporter Importin 13.

Fatima S, Wagstaff KM, Lieu KG, Davies RG, Tanaka SS, Yamaguchi YL, Loveland KL, Tam PP, Jans DA.

Biochim Biophys Acta Mol Cell Res. 2017 Mar;1864(3):546-561. doi: 10.1016/j.bbamcr.2016.12.017. Epub 2016 Dec 16.


The immune evasion function of J and Beilong virus V proteins is distinct from that of other paramyxoviruses, consistent with their inclusion in the proposed genus Jeilongvirus.

Audsley MD, Marsh GA, Lieu KG, Tachedjian M, Joubert DA, Wang LF, Jans DA, Moseley GW.

J Gen Virol. 2016 Mar;97(3):581-92. doi: 10.1099/jgv.0.000388. Epub 2015 Dec 24.


The non-pathogenic Henipavirus Cedar paramyxovirus phosphoprotein has a compromised ability to target STAT1 and STAT2.

Lieu KG, Marsh GA, Wang LF, Netter HJ.

Antiviral Res. 2015 Dec;124:69-76. doi: 10.1016/j.antiviral.2015.09.017. Epub 2015 Oct 23.


The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain.

Lieu KG, Shim EH, Wang J, Lokareddy RK, Tao T, Cingolani G, Zambetti GP, Jans DA.

J Cell Biol. 2014 May 12;205(3):301-12. doi: 10.1083/jcb.201304055.


Nucleocytoplasmic shuttling of the Duchenne muscular dystrophy gene product dystrophin Dp71d is dependent on the importin α/β and CRM1 nuclear transporters and microtubule motor dynein.

Suárez-Sánchez R, Aguilar A, Wagstaff KM, Velez G, Azuara-Medina PM, Gomez P, Vásquez-Limeta A, Hernández-Hernández O, Lieu KG, Jans DA, Cisneros B.

Biochim Biophys Acta. 2014 May;1843(5):985-1001. doi: 10.1016/j.bbamcr.2014.01.027. Epub 2014 Jan 30.


Bovine ephemeral fever rhabdovirus α1 protein has viroporin-like properties and binds importin β1 and importin 7.

Joubert DA, Blasdell KR, Audsley MD, Trinidad L, Monaghan P, Dave KA, Lieu KG, Amos-Ritchie R, Jans DA, Moseley GW, Gorman JJ, Walker PJ.

J Virol. 2014 Feb;88(3):1591-603. doi: 10.1128/JVI.01812-13. Epub 2013 Nov 20.


The rabies virus interferon antagonist P protein interacts with activated STAT3 and inhibits Gp130 receptor signaling.

Lieu KG, Brice A, Wiltzer L, Hirst B, Jans DA, Blondel D, Moseley GW.

J Virol. 2013 Jul;87(14):8261-5. doi: 10.1128/JVI.00989-13. Epub 2013 May 22.


70-kDa heat shock cognate protein hsc70 mediates calmodulin-dependent nuclear import of the sex-determining factor SRY.

Kaur G, Lieu KG, Jans DA.

J Biol Chem. 2013 Feb 8;288(6):4148-57. doi: 10.1074/jbc.M112.436741. Epub 2012 Dec 12.


Importin alpha2-interacting proteins with nuclear roles during mammalian spermatogenesis.

Ly-Huynh JD, Lieu KG, Major AT, Whiley PA, Holt JE, Loveland KL, Jans DA.

Biol Reprod. 2011 Dec;85(6):1191-202. doi: 10.1095/biolreprod.111.091686. Epub 2011 Sep 7.


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