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Zinc Oxide Films with High Transparency and Crystallinity Prepared by a Low Temperature Spatial Atomic Layer Deposition Process.

Zhao MJ, Sun ZT, Hsu CH, Huang PH, Zhang XY, Wu WY, Gao P, Qiu Y, Lien SY, Zhu WZ.

Nanomaterials (Basel). 2020 Mar 4;10(3). pii: E459. doi: 10.3390/nano10030459.


Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon.

Sinclair-Waters M, Ødegård J, Korsvoll SA, Moen T, Lien S, Primmer CR, Barson NJ.

Genet Sel Evol. 2020 Feb 12;52(1):9. doi: 10.1186/s12711-020-0529-8.


Genetic Differentiation in Hatchery and Stocked Populations of Sea Trout in the Southern Baltic: Selection Evidence at SNP Loci.

Bernaś R, Poćwierz-Kotus A, Árnyasi M, Kent MP, Lien S, Wenne R.

Genes (Basel). 2020 Feb 10;11(2). pii: E184. doi: 10.3390/genes11020184.


Modular chromosome rearrangements reveal parallel and nonparallel adaptation in a marine fish.

Kess T, Bentzen P, Lehnert SJ, Sylvester EVA, Lien S, Kent MP, Sinclair-Waters M, Morris C, Wringe B, Fairweather R, Bradbury IR.

Ecol Evol. 2020 Jan 11;10(2):638-653. doi: 10.1002/ece3.5828. eCollection 2020 Jan.


Northern European Salmo trutta (L.) populations are genetically divergent across geographical regions and environmental gradients.

Bekkevold D, Höjesjö J, Nielsen EE, Aldvén D, Als TD, Sodeland M, Kent MP, Lien S, Hansen MM.

Evol Appl. 2019 Nov 1;13(2):400-416. doi: 10.1111/eva.12877. eCollection 2020 Feb.


IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function.

St Paul M, Saibil SD, Lien SC, Han S, Sayad A, Mulder DT, Garcia-Batres CR, Elford AR, Israni-Winger K, Robert-Tissot C, Zon M, Katz SR, Shaw PA, Clarke BA, Bernardini MQ, Nguyen LT, Haibe-Kains B, Pugh TJ, Ohashi PS.

Cancer Immunol Res. 2020 Mar;8(3):321-333. doi: 10.1158/2326-6066.CIR-19-0521. Epub 2020 Jan 21.


A genome-wide linkage map for the house sparrow (Passer domesticus) provides insights into the evolutionary history of the avian genome.

Hagen IJ, Lien S, Billing AM, Elgvin TO, Trier C, Niskanen AK, Tarka M, Slate J, Saetre GP, Jensen H.

Mol Ecol Resour. 2020 Mar;20(2):544-559. doi: 10.1111/1755-0998.13134. Epub 2020 Jan 31.


Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color.

Helgeland H, Sodeland M, Zoric N, Torgersen JS, Grammes F, von Lintig J, Moen T, Kjøglum S, Lien S, Våge DI.

Sci Rep. 2019 Dec 27;9(1):20061. doi: 10.1038/s41598-019-56438-3.


Publisher Correction: Sex-dependent dominance maintains migration supergene in rainbow trout.

Pearse DE, Barson NJ, Nome T, Gao G, Campbell MA, Abadía-Cardoso A, Anderson EC, Rundio DE, Williams TH, Naish KA, Moen T, Liu S, Kent M, Moser M, Minkley DR, Rondeau EB, Brieuc MSO, Sandve SR, Miller MR, Cedillo L, Baruch K, Hernandez AG, Ben-Zvi G, Shem-Tov D, Barad O, Kuzishchin K, Garza JC, Lindley ST, Koop BF, Thorgaard GH, Palti Y, Lien S.

Nat Ecol Evol. 2020 Jan;4(1):170. doi: 10.1038/s41559-019-1076-y.


Sex-dependent dominance maintains migration supergene in rainbow trout.

Pearse DE, Barson NJ, Nome T, Gao G, Campbell MA, Abadía-Cardoso A, Anderson EC, Rundio DE, Williams TH, Naish KA, Moen T, Liu S, Kent M, Moser M, Minkley DR, Rondeau EB, Brieuc MSO, Sandve SR, Miller MR, Cedillo L, Baruch K, Hernandez AG, Ben-Zvi G, Shem-Tov D, Barad O, Kuzishchin K, Garza JC, Lindley ST, Koop BF, Thorgaard GH, Palti Y, Lien S.

Nat Ecol Evol. 2019 Dec;3(12):1731-1742. doi: 10.1038/s41559-019-1044-6. Epub 2019 Nov 25. Erratum in: Nat Ecol Evol. 2019 Dec 9;:.


Strong selection pressures maintain divergence on genomic islands in Atlantic cod (Gadus morhua L.) populations.

Rodríguez-Ramilo ST, Baranski M, Moghadam H, Grove H, Lien S, Goddard ME, Meuwissen THE, Sonesson AK.

Genet Sel Evol. 2019 Oct 29;51(1):61. doi: 10.1186/s12711-019-0503-5.


Anti-inflammatory Compound Shows Therapeutic Safety and Efficacy against Flavivirus Infection.

Chuang FK, Huang SM, Liao CL, Lee AR, Lien SP, Chiu YL, Chang TH, Tsai PL, Lin RJ, Shih CC, Tsai YJ, Lin GJ, Yen LC.

Antimicrob Agents Chemother. 2019 Dec 20;64(1). pii: e00941-19. doi: 10.1128/AAC.00941-19. Print 2019 Dec 20.


Low Reflection and Low Surface Recombination Rate Nano-Needle Texture Formed by Two-Step Etching for Solar Cells.

Hsu CH, Liu SM, Lien SY, Zhang XY, Cho YS, Huang YH, Zhang S, Chen SY, Zhu WZ.

Nanomaterials (Basel). 2019 Sep 29;9(10). pii: E1392. doi: 10.3390/nano9101392.


Domain 4 of pneumolysin from Streptococcus pneumoniae is a multifunctional domain contributing TLR4 activating and hemolytic activity.

Chiu FF, Leng CH, Ding YJ, Chang JC, Chang LS, Lien SP, Chen HW, Siu LK, Liu SJ.

Biochem Biophys Res Commun. 2019 Oct 1;517(4):596-602. doi: 10.1016/j.bbrc.2019.07.063. Epub 2019 Aug 5.


Naturally occurring mutations in PB1 affect influenza A virus replication fidelity, virulence, and adaptability.

Lin RW, Chen GW, Sung HH, Lin RJ, Yen LC, Tseng YL, Chang YK, Lien SP, Shih SR, Liao CL.

J Biomed Sci. 2019 Jul 31;26(1):55. doi: 10.1186/s12929-019-0547-4.


Anti-inflammatory and anti-osteoarthritis effects of Cm-02 and Ck-02.

Ho YJ, Lu JW, Ho LJ, Lai JH, Huang HS, Lee CC, Lin TY, Lien SB, Lin LC, Chen LW, Gong Z, Shen MC, Liu FC.

Biochem Biophys Res Commun. 2019 Sep 10;517(1):155-163. doi: 10.1016/j.bbrc.2019.07.036. Epub 2019 Jul 25.


Deposition of Silicon-Based Stacked Layers for Flexible Encapsulation of Organic Light Emitting Diodes.

Hsu CH, Lin YS, Wu HY, Zhang XY, Wu WY, Lien SY, Wuu DS, Jiang YL.

Nanomaterials (Basel). 2019 Jul 23;9(7). pii: E1053. doi: 10.3390/nano9071053.


Genomic signatures and correlates of widespread population declines in salmon.

Lehnert SJ, Kess T, Bentzen P, Kent MP, Lien S, Gilbey J, Clément M, Jeffery NW, Waples RS, Bradbury IR.

Nat Commun. 2019 Jul 5;10(1):2996. doi: 10.1038/s41467-019-10972-w.


A migration-associated supergene reveals loss of biocomplexity in Atlantic cod.

Kess T, Bentzen P, Lehnert SJ, Sylvester EVA, Lien S, Kent MP, Sinclair-Waters M, Morris CJ, Regular P, Fairweather R, Bradbury IR.

Sci Adv. 2019 Jun 26;5(6):eaav2461. doi: 10.1126/sciadv.aav2461. eCollection 2019 Jun.


Serum Concentrations of Oocyte-Secreted Factors BMP15 and GDF9 During IVF and in Women With Reproductive Pathologies.

Riepsamen AH, Chan K, Lien S, Sweeten P, Donoghoe MW, Walker G, Fraison EHJ, Stocker WA, Walton KL, Harrison CA, Ledger WL, Robertson DM, Gilchrist RB.

Endocrinology. 2019 Oct 1;160(10):2298-2313. doi: 10.1210/en.2019-00264.


Enhanced Si Passivation and PERC Solar Cell Efficiency by Atomic Layer Deposited Aluminum Oxide with Two-step Post Annealing.

Hsu CH, Cho YS, Wu WY, Lien SY, Zhang XY, Zhu WZ, Zhang S, Chen SY.

Nanoscale Res Lett. 2019 Apr 18;14(1):139. doi: 10.1186/s11671-019-2969-z.


Chromosome-scale assemblies reveal the structural evolution of African cichlid genomes.

Conte MA, Joshi R, Moore EC, Nandamuri SP, Gammerdinger WJ, Roberts RB, Carleton KL, Lien S, Kocher TD.

Gigascience. 2019 Apr 1;8(4). pii: giz030. doi: 10.1093/gigascience/giz030.


Canine Parvovirus-2c (CPV-2c) Infection in Wild Asian Palm Civets (Paradoxurus hermaphroditus) in Singapore.

Xinyu T, Min CS, Yifan W, Lien SM, Chan A, Hui TX, Lee B, Yelin W, Chia-Da H, Oh S, Fernandez CJ, Taoqi H.

J Wildl Dis. 2019 Oct;55(4):965-969. Epub 2019 Mar 28.


An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE).

Clouthier DL, Lien SC, Yang SYC, Nguyen LT, Manem VSK, Gray D, Ryczko M, Razak ARA, Lewin J, Lheureux S, Colombo I, Bedard PL, Cescon D, Spreafico A, Butler MO, Hansen AR, Jang RW, Ghai S, Weinreb I, Sotov V, Gadalla R, Noamani B, Guo M, Elston S, Giesler A, Hakgor S, Jiang H, McGaha T, Brooks DG, Haibe-Kains B, Pugh TJ, Ohashi PS, Siu LL.

J Immunother Cancer. 2019 Mar 13;7(1):72. doi: 10.1186/s40425-019-0541-0.


Temperature-Dependent HfO2/Si Interface Structural Evolution and its Mechanism.

Zhang XY, Hsu CH, Lien SY, Wu WY, Ou SL, Chen SY, Huang W, Zhu WZ, Xiong FB, Zhang S.

Nanoscale Res Lett. 2019 Mar 7;14(1):83. doi: 10.1186/s11671-019-2915-0.


The Chromosome-Level Genome Assembly of European Grayling Reveals Aspects of a Unique Genome Evolution Process Within Salmonids.

Sävilammi T, Primmer CR, Varadharajan S, Guyomard R, Guiguen Y, Sandve SR, Vøllestad LA, Papakostas S, Lien S.

G3 (Bethesda). 2019 May 7;9(5):1283-1294. doi: 10.1534/g3.118.200919.


Chromosome polymorphisms track trans-Atlantic divergence and secondary contact in Atlantic salmon.

Lehnert SJ, Bentzen P, Kess T, Lien S, Horne JB, Clément M, Bradbury IR.

Mol Ecol. 2019 Apr;28(8):2074-2087. doi: 10.1111/mec.15065. Epub 2019 Apr 29.


Cumulin and FSH Cooperate to Regulate Inhibin B and Activin B Production by Human Granulosa-Lutein Cells In Vitro.

Richani D, Constance K, Lien S, Agapiou D, Stocker WA, Hedger MP, Ledger WL, Thompson JG, Robertson DM, Mottershead DG, Walton KL, Harrison CA, Gilchrist RB.

Endocrinology. 2019 Apr 1;160(4):853-862. doi: 10.1210/en.2018-01026.


Characterization of a male specific region containing a candidate sex determining gene in Atlantic cod.

Kirubakaran TG, Andersen Ø, De Rosa MC, Andersstuen T, Hallan K, Kent MP, Lien S.

Sci Rep. 2019 Jan 15;9(1):116. doi: 10.1038/s41598-018-36748-8.


Oxidative Stress and Nonalcoholic Fatty Liver Disease in Hemodialysis Patients.

Wu PJ, Chen JB, Lee WC, Ng HY, Lien SC, Tsai PY, Wu CH, Lee CT, Chiou TT.

Biomed Res Int. 2018 Nov 1;2018:3961748. doi: 10.1155/2018/3961748. eCollection 2018.


A genetic linkage map for the salmon louse (Lepeophtheirus salmonis): evidence for high male:female and inter-familial recombination rate differences.

Danzmann RG, Norman JD, Rondeau EB, Messmer AM, Kent MP, Lien S, Igboeli O, Fast MD, Koop BF.

Mol Genet Genomics. 2019 Apr;294(2):343-363. doi: 10.1007/s00438-018-1513-7. Epub 2018 Nov 20.


Development and Validation of 58K SNP-Array and High-Density Linkage Map in Nile Tilapia (O. niloticus).

Joshi R, Árnyasi M, Lien S, Gjøen HM, Alvarez AT, Kent M.

Front Genet. 2018 Oct 15;9:472. doi: 10.3389/fgene.2018.00472. eCollection 2018.


The Grayling Genome Reveals Selection on Gene Expression Regulation after Whole-Genome Duplication.

Varadharajan S, Sandve SR, Gillard GB, Tørresen OK, Mulugeta TD, Hvidsten TR, Lien S, Asbjørn Vøllestad L, Jentoft S, Nederbragt AJ, Jakobsen KS.

Genome Biol Evol. 2018 Oct 1;10(10):2785-2800. doi: 10.1093/gbe/evy201.


Signs of adaptation to trace metal contamination in a common urban bird.

Andrew SC, Taylor MP, Lundregan S, Lien S, Jensen H, Griffith SC.

Sci Total Environ. 2019 Feb 10;650(Pt 1):679-686. doi: 10.1016/j.scitotenv.2018.09.052. Epub 2018 Sep 5.


Inferences of genetic architecture of bill morphology in house sparrow using a high-density SNP array point to a polygenic basis.

Lundregan SL, Hagen IJ, Gohli J, Niskanen AK, Kemppainen P, Ringsby TH, Kvalnes T, Pärn H, Rønning B, Holand H, Ranke PS, Båtnes AS, Selvik LK, Lien S, Saether BE, Husby A, Jensen H.

Mol Ecol. 2018 Sep;27(17):3498-3514. doi: 10.1111/mec.14811. Epub 2018 Aug 11.


Vestibular Injury After Low-Intensity Blast Exposure.

Lien S, Dickman JD.

Front Neurol. 2018 May 14;9:297. doi: 10.3389/fneur.2018.00297. eCollection 2018.


Genome-wide association study reveals a QTL and strong candidate genes for umbilical hernia in pigs on SSC14.

Grindflek E, Hansen MHS, Lien S, van Son M.

BMC Genomics. 2018 May 29;19(1):412. doi: 10.1186/s12864-018-4812-9.


Arthroprotective Effects of Cf-02 Sharing Structural Similarity with Quercetin.

Liu FC, Lu JW, Chien CY, Huang HS, Lee CC, Lien SB, Lin LC, Chen LW, Ho YJ, Shen MC, Ho LJ, Lai JH.

Int J Mol Sci. 2018 May 14;19(5). pii: E1453. doi: 10.3390/ijms19051453.


A New Single Nucleotide Polymorphism Database for Rainbow Trout Generated Through Whole Genome Resequencing.

Gao G, Nome T, Pearse DE, Moen T, Naish KA, Thorgaard GH, Lien S, Palti Y.

Front Genet. 2018 Apr 24;9:147. doi: 10.3389/fgene.2018.00147. eCollection 2018.


A 200K SNP chip reveals a novel Pacific salmon louse genotype linked to differential efficacy of emamectin benzoate.

Messmer AM, Leong JS, Rondeau EB, Mueller A, Despins CA, Minkley DR, Kent MP, Lien S, Boyce B, Morrison D, Fast MD, Norman JD, Danzmann RG, Koop BF.

Mar Genomics. 2018 Jul;40:45-57. doi: 10.1016/j.margen.2018.03.005. Epub 2018 Apr 16.



Kirubakaran TG, Grove H, Kent MP, Sandve SR, Baranski M, Nome T, De Rosa MC, Righino B, Johansen T, Otterå H, Sonesson A, Lien SR, Andersen Ø.

Mol Ecol. 2018 Mar;27(6):1520. doi: 10.1111/mec.14530. No abstract available.


Evolution of Sex Determination Loci in Atlantic Salmon.

Kijas J, McWilliam S, Naval Sanchez M, Kube P, King H, Evans B, Nome T, Lien S, Verbyla K.

Sci Rep. 2018 Apr 4;8(1):5664. doi: 10.1038/s41598-018-23984-1.


Prospective analysis of bleeding events in left ventricular assist device patients.

Sherazi S, Kouides P, Francis C, Lowenstein CJ, Refaai M, Conley G, Johnson BA, Muchnik E, Lien S, Massey HT, Alexis JD.

Int J Artif Organs. 2018 May;41(5):269-276. doi: 10.1177/0391398818762353. Epub 2018 Mar 22.


Chondroprotective Effects and Mechanisms of Dextromethorphan: Repurposing Antitussive Medication for Osteoarthritis Treatment.

Chen LW, Liu FC, Hung LF, Huang CY, Lien SB, Lin LC, Lai JH, Ho LJ.

Int J Mol Sci. 2018 Mar 12;19(3). pii: E825. doi: 10.3390/ijms19030825.


Functional outcomes and quality of life after a 6-month early intervention program for oral cancer survivors: a single-arm clinical trial.

Chen YH, Liang WA, Hsu CY, Guo SL, Lien SH, Tseng HJ, Chao YH.

PeerJ. 2018 Feb 21;6:e4419. doi: 10.7717/peerj.4419. eCollection 2018.


Life-stage-associated remodelling of lipid metabolism regulation in Atlantic salmon.

Gillard G, Harvey TN, Gjuvsland A, Jin Y, Thomassen M, Lien S, Leaver M, Torgersen JS, Hvidsten TR, Vik JO, Sandve SR.

Mol Ecol. 2018 Mar;27(5):1200-1213. doi: 10.1111/mec.14533. Epub 2018 Mar 12.


Unravelling genetic variation underlying de novo-synthesis of bovine milk fatty acids.

Knutsen TM, Olsen HG, Tafintseva V, Svendsen M, Kohler A, Kent MP, Lien S.

Sci Rep. 2018 Feb 1;8(1):2179. doi: 10.1038/s41598-018-20476-0.


Ancient chromosomal rearrangement associated with local adaptation of a postglacially colonized population of Atlantic Cod in the northwest Atlantic.

Sinclair-Waters M, Bradbury IR, Morris CJ, Lien S, Kent MP, Bentzen P.

Mol Ecol. 2018 Jan;27(2):339-351. doi: 10.1111/mec.14442. Epub 2017 Dec 27.


Mapping of quantitative trait loci associated with size, shape, and parr mark traits using first- and second-generation backcrosses between European and North American Atlantic salmon (Salmo salar).

Pedersen S, Liu L, Glebe B, Leadbeater S, Lien S, Boulding EG.

Genome. 2018 Jan;61(1):33-42. doi: 10.1139/gen-2017-0026. Epub 2017 Oct 16.


Exploiting whole genome sequence data to fine map and characterize candidate genes within a quantitative trait loci region affecting androstenone on porcine chromosome 5.

van Son M, Agarwal R, Kent MP, Grove H, Grindflek E, Lien S.

Anim Genet. 2017 Dec;48(6):653-659. doi: 10.1111/age.12615. Epub 2017 Oct 16.

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