Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 131

1.

The multifunctional peptide DN-9 produced peripherally acting antinociception in inflammatory and neuropathic pain via mu and kappa opioid receptors.

Xu B, Zhang M, Shi X, Zhang R, Chen D, Chen Y, Wang Z, Qiu Y, Zhang T, Xu K, Zhang X, Liedtke W, Wang R, Fang Q.

Br J Pharmacol. 2019 Aug 24. doi: 10.1111/bph.14848. [Epub ahead of print]

PMID:
31444977
2.

TRPV4 inhibition prevents increased water diffusion and blood-retina barrier breakdown in the retina of streptozotocin-induced diabetic mice.

Orduña Ríos M, Noguez Imm R, Hernández Godínez NM, Bautista Cortes AM, López Escalante DD, Liedtke W, Martínez Torres A, Concha L, Thébault S.

PLoS One. 2019 May 2;14(5):e0212158. doi: 10.1371/journal.pone.0212158. eCollection 2019.

3.

TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension.

Gilchrist CL, Leddy HA, Kaye L, Case ND, Rothenberg KE, Little D, Liedtke W, Hoffman BD, Guilak F.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1992-1997. doi: 10.1073/pnas.1811095116. Epub 2019 Jan 23.

4.

Author Correction: Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference.

Arredondo Zamarripa D, Noguez Imm R, Bautista Cortés AM, Vázquez Ruíz O, Bernardini M, Fiorio Pla A, Gkika D, Prevarskaya N, López-Casillas F, Liedtke W, Clapp C, Thébault S.

Sci Rep. 2018 Jun 20;8(1):9652. doi: 10.1038/s41598-018-27642-4.

5.

Trpv4 Mediates Hypotonic Inhibition of Central Osmosensory Neurons via Taurine Gliotransmission.

Ciura S, Prager-Khoutorsky M, Thirouin ZS, Wyrosdic JC, Olson JE, Liedtke W, Bourque CW.

Cell Rep. 2018 May 22;23(8):2245-2253. doi: 10.1016/j.celrep.2018.04.090.

6.

Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion.

Mannaa M, Markó L, Balogh A, Vigolo E, N'diaye G, Kaßmann M, Michalick L, Weichelt U, Schmidt-Ott KM, Liedtke WB, Huang Y, Müller DN, Kuebler WM, Gollasch M.

Sci Rep. 2018 Mar 20;8(1):4878. doi: 10.1038/s41598-018-23165-0.

7.

Publisher Correction: A craniofacial-specific monosynaptic circuit enables heightened affective pain.

Rodriguez E, Sakurai K, Xu J, Chen Y, Toda K, Zhao S, Han BX, Ryu D, Yin H, Liedtke W, Wang F.

Nat Neurosci. 2018 Jun;21(6):896. doi: 10.1038/s41593-018-0103-7.

PMID:
29549316
8.

TRP Channels and Pain.

González-Ramírez R, Chen Y, Liedtke WB, Morales-Lázaro SL.

In: Emir TLR, editor. Neurobiology of TRP Channels. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2017. Chapter 8.

9.

Osmomechanical-Sensitive TRPV Channels in Mammals.

Moore C, Liedtke WB.

In: Emir TLR, editor. Neurobiology of TRP Channels. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2017. Chapter 5.

10.

Regulation of Pain and Itch by TRP Channels.

Moore C, Gupta R, Jordt SE, Chen Y, Liedtke WB.

Neurosci Bull. 2018 Feb;34(1):120-142. doi: 10.1007/s12264-017-0200-8. Epub 2017 Dec 27. Review.

11.

A craniofacial-specific monosynaptic circuit enables heightened affective pain.

Rodriguez E, Sakurai K, Xu J, Chen Y, Toda K, Zhao S, Han BX, Ryu D, Yin H, Liedtke W, Wang F.

Nat Neurosci. 2017 Dec;20(12):1734-1743. doi: 10.1038/s41593-017-0012-1. Epub 2017 Nov 13. Erratum in: Nat Neurosci. 2018 Mar 16;:.

12.

Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference.

Arredondo Zamarripa D, Noguez Imm R, Bautista Cortés AM, Vázquez Ruíz O, Bernardini M, Fiorio Pla A, Gkika D, Prevarskaya N, López-Casillas F, Liedtke W, Clapp C, Thébault S.

Sci Rep. 2017 Oct 12;7(1):13094. doi: 10.1038/s41598-017-13621-8. Erratum in: Sci Rep. 2018 Jun 20;8(1):9652.

13.

Role of Piezo Channels in Joint Health and Injury.

Lee W, Guilak F, Liedtke W.

Curr Top Membr. 2017;79:263-273. doi: 10.1016/bs.ctm.2016.10.003. Epub 2017 Jan 11. Review.

14.

The anti-migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel.

Benemei S, De Logu F, Li Puma S, Marone IM, Coppi E, Ugolini F, Liedtke W, Pollastro F, Appendino G, Geppetti P, Materazzi S, Nassini R.

Br J Pharmacol. 2017 Sep;174(17):2897-2911. doi: 10.1111/bph.13917. Epub 2017 Jul 20.

15.

TRPV4 Moves toward Center-Fold in Rosacea Pathogenesis.

Chen Y, Moore CD, Zhang JY, Hall RP 3rd, MacLeod AS, Liedtke W.

J Invest Dermatol. 2017 Apr;137(4):801-804. doi: 10.1016/j.jid.2016.12.013.

16.

Deconstructing mammalian thermoregulation.

Liedtke WB.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1765-1767. doi: 10.1073/pnas.1620579114. Epub 2017 Feb 8. No abstract available.

17.

Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells.

Solís-López A, Kriebs U, Marx A, Mannebach S, Liedtke WB, Caterina MJ, Freichel M, Tsvilovskyy VV.

PLoS One. 2017 Feb 3;12(2):e0171366. doi: 10.1371/journal.pone.0171366. eCollection 2017.

18.

TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity.

Seth RK, Das S, Dattaroy D, Chandrashekaran V, Alhasson F, Michelotti G, Nagarkatti M, Nagarkatti P, Diehl AM, Bell PD, Liedtke W, Chatterjee S.

Free Radic Biol Med. 2017 Jan;102:260-273. doi: 10.1016/j.freeradbiomed.2016.11.047. Epub 2016 Nov 29.

19.

Transient Receptor Potential Vanilloid 4 and Serum Glucocorticoid-regulated Kinase 1 Are Critical Mediators of Lung Injury in Overventilated Mice In Vivo.

Michalick L, Erfinanda L, Weichelt U, van der Giet M, Liedtke W, Kuebler WM.

Anesthesiology. 2017 Feb;126(2):300-311. doi: 10.1097/ALN.0000000000001443.

PMID:
27861175
20.

Pleiotropic function of TRPV4 ion channels in the central nervous system.

Kanju P, Liedtke W.

Exp Physiol. 2016 Dec 1;101(12):1472-1476. doi: 10.1113/EP085790. Epub 2016 Nov 8. Review.

21.

Isolated Deep Ear Canal Pain: Possible Role of Auricular Branch of Vagus Nerve-Case Illustrations with Cadaveric Correlation.

Watanabe K, Tubbs RS, Satoh S, Zomorodi AR, Liedtke W, Labidi M, Friedman AH, Fukushima T.

World Neurosurg. 2016 Dec;96:293-301. doi: 10.1016/j.wneu.2016.08.102. Epub 2016 Sep 1.

PMID:
27593717
22.

Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis.

O'Conor CJ, Ramalingam S, Zelenski NA, Benefield HC, Rigo I, Little D, Wu CL, Chen D, Liedtke W, McNulty AL, Guilak F.

Sci Rep. 2016 Jul 8;6:29053. doi: 10.1038/srep29053.

23.

Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.

Kanju P, Chen Y, Lee W, Yeo M, Lee SH, Romac J, Shahid R, Fan P, Gooden DM, Simon SA, Spasojevic I, Mook RA, Liddle RA, Guilak F, Liedtke WB.

Sci Rep. 2016 Jun 1;6:26894. doi: 10.1038/srep26894.

24.

Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch.

Chen Y, Fang Q, Wang Z, Zhang JY, MacLeod AS, Hall RP, Liedtke WB.

J Biol Chem. 2016 May 6;291(19):10252-62. doi: 10.1074/jbc.M116.716464. Epub 2016 Mar 9.

25.

P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells.

Rajasekhar P, Poole DP, Liedtke W, Bunnett NW, Veldhuis NA.

J Biol Chem. 2015 Nov 27;290(48):29051-62. doi: 10.1074/jbc.M115.689729. Epub 2015 Oct 16.

26.

ΔN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress.

Zaelzer C, Hua P, Prager-Khoutorsky M, Ciura S, Voisin DL, Liedtke W, Bourque CW.

Cell Rep. 2015 Oct 6;13(1):23-30. doi: 10.1016/j.celrep.2015.08.061. Epub 2015 Sep 17.

27.

Transient receptor potential vanilloid 4 inhibits mouse colonic motility by activating NO-dependent enteric neurotransmission.

Fichna J, Poole DP, Veldhuis N, MacEachern SJ, Saur D, Zakrzewski PK, Cygankiewicz AI, Mokrowiecka A, Małecka-Panas E, Krajewska WM, Liedtke W, Steinhoff MS, Timmermans JP, Bunnett NW, Sharkey KA, Storr MA.

J Mol Med (Berl). 2015 Dec;93(12):1297-309. doi: 10.1007/s00109-015-1336-5. Epub 2015 Sep 2.

PMID:
26330151
28.

Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury.

Yin J, Michalick L, Tang C, Tabuchi A, Goldenberg N, Dan Q, Awwad K, Wang L, Erfinanda L, Nouailles G, Witzenrath M, Vogelzang A, Lv L, Lee WL, Zhang H, Rotstein O, Kapus A, Szaszi K, Fleming I, Liedtke WB, Kuppe H, Kuebler WM.

Am J Respir Cell Mol Biol. 2016 Mar;54(3):370-83. doi: 10.1165/rcmb.2014-0225OC.

PMID:
26222277
29.

Functional coupling of TRPV4, IK, and SK channels contributes to Ca(2+)-dependent endothelial injury in rodent lung.

Lin MT, Jian MY, Taylor MS, Cioffi DL, Yap FC, Liedtke W, Townsley MI.

Pulm Circ. 2015 Jun;5(2):279-90. doi: 10.1086/680166.

30.

Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome.

Cenac N, Bautzova T, Le Faouder P, Veldhuis NA, Poole DP, Rolland C, Bertrand J, Liedtke W, Dubourdeau M, Bertrand-Michel J, Zecchi L, Stanghellini V, Bunnett NW, Barbara G, Vergnolle N.

Gastroenterology. 2015 Aug;149(2):433-44.e7. doi: 10.1053/j.gastro.2015.04.011. Epub 2015 Apr 22.

PMID:
25911511
31.

Lack of evidence for ectopic sprouting of genetically labeled Aβ touch afferents in inflammatory and neuropathic trigeminal pain.

Zhang Y, Chen Y, Liedtke W, Wang F.

Mol Pain. 2015 Apr 10;11:18. doi: 10.1186/s12990-015-0017-2.

32.

Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain.

Zhao P, Lieu T, Barlow N, Sostegni S, Haerteis S, Korbmacher C, Liedtke W, Jimenez-Vargas NN, Vanner SJ, Bunnett NW.

J Biol Chem. 2015 May 29;290(22):13875-87. doi: 10.1074/jbc.M115.642736. Epub 2015 Apr 15.

33.

TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction.

Goldenberg NM, Wang L, Ranke H, Liedtke W, Tabuchi A, Kuebler WM.

Anesthesiology. 2015 Jun;122(6):1338-48. doi: 10.1097/ALN.0000000000000647.

PMID:
25815455
34.

Type VI Collagen Regulates Pericellular Matrix Properties, Chondrocyte Swelling, and Mechanotransduction in Mouse Articular Cartilage.

Zelenski NA, Leddy HA, Sanchez-Adams J, Zhang J, Bonaldo P, Liedtke W, Guilak F.

Arthritis Rheumatol. 2015 May;67(5):1286-94. doi: 10.1002/art.39034.

35.

TRPV4 as a therapeutic target for joint diseases.

McNulty AL, Leddy HA, Liedtke W, Guilak F.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Apr;388(4):437-50. doi: 10.1007/s00210-014-1078-x. Epub 2014 Dec 18. Review.

36.
37.

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage.

Lee W, Leddy HA, Chen Y, Lee SH, Zelenski NA, McNulty AL, Wu J, Beicker KN, Coles J, Zauscher S, Grandl J, Sachs F, Guilak F, Liedtke WB.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5114-22. doi: 10.1073/pnas.1414298111. Epub 2014 Nov 10.

38.

TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor.

Chen Y, Kanju P, Fang Q, Lee SH, Parekh PK, Lee W, Moore C, Brenner D, Gereau RW 4th, Wang F, Liedtke W.

Pain. 2014 Dec;155(12):2662-72. doi: 10.1016/j.pain.2014.09.033. Epub 2014 Oct 2.

39.

TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour.

Lindy AS, Parekh PK, Zhu R, Kanju P, Chintapalli SV, Tsvilovskyy V, Patterson RL, Anishkin A, van Rossum DB, Liedtke WB.

Nat Commun. 2014 Sep 2;5:4734. doi: 10.1038/ncomms5734.

40.

Keratinocyte growth regulation TRP-ed up over downregulated TRPV4?

Liedtke W, Zhang JY, Hall RP 3rd, Steinhoff M.

J Invest Dermatol. 2014 Sep;134(9):2310-2312. doi: 10.1038/jid.2014.250.

41.

Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.

Zhao P, Lieu T, Barlow N, Metcalf M, Veldhuis NA, Jensen DD, Kocan M, Sostegni S, Haerteis S, Baraznenok V, Henderson I, Lindström E, Guerrero-Alba R, Valdez-Morales EE, Liedtke W, McIntyre P, Vanner SJ, Korbmacher C, Bunnett NW.

J Biol Chem. 2014 Sep 26;289(39):27215-34. doi: 10.1074/jbc.M114.599712. Epub 2014 Aug 12. Erratum in: J Biol Chem. 2014 Dec 26;289(52):35858.

42.

Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature.

Chen L, Kaßmann M, Sendeski M, Tsvetkov D, Marko L, Michalick L, Riehle M, Liedtke WB, Kuebler WM, Harteneck C, Tepel M, Patzak A, Gollasch M.

Acta Physiol (Oxf). 2015 Feb;213(2):481-91. doi: 10.1111/apha.12355. Epub 2014 Aug 21.

PMID:
25069877
43.

A Classic Innate Behavior, Sodium Appetite, Is Driven by Hypothalamic Gene-Regulatory Programs Previously Linked to Addiction and Reward.

Liedtke W.

In: De Luca LA Jr, Menani JV, Johnson AK, editors. Neurobiology of Body Fluid Homeostasis: Transduction and Integration. Boca Raton (FL): CRC Press/Taylor & Francis; 2014. Chapter 12.

44.

Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations.

Leddy HA, McNulty AL, Lee SH, Rothfusz NE, Gloss B, Kirby ML, Hutson MR, Cohn DH, Guilak F, Liedtke W.

FASEB J. 2014 Jun;28(6):2525-37. doi: 10.1096/fj.13-245936. Epub 2014 Feb 27.

45.

TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading.

O'Conor CJ, Leddy HA, Benefield HC, Liedtke WB, Guilak F.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1316-21. doi: 10.1073/pnas.1319569111. Epub 2014 Jan 13.

46.

Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias.

Leddy HA, McNulty AL, Guilak F, Liedtke W.

Rare Dis. 2014 Oct 30;2(1):e962971. doi: 10.4161/2167549X.2014.962971. eCollection 2014.

47.

Decoding the language of epigenetics during neural development is key for understanding development as well as developmental neurotoxicity.

Yeo M, Patisaul H, Liedtke W.

Epigenetics. 2013 Nov;8(11):1128-32. doi: 10.4161/epi.26406. Epub 2013 Sep 26.

PMID:
24071811
48.

UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling.

Moore C, Cevikbas F, Pasolli HA, Chen Y, Kong W, Kempkes C, Parekh P, Lee SH, Kontchou NA, Yeh I, Jokerst NM, Fuchs E, Steinhoff M, Liedtke WB.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3225-34. doi: 10.1073/pnas.1312933110. Epub 2013 Aug 8. Erratum in: Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15502. Ye, Iwei [corrected to Yeh, Iwei].

49.

TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension.

Xia Y, Fu Z, Hu J, Huang C, Paudel O, Cai S, Liedtke W, Sham JS.

Am J Physiol Cell Physiol. 2013 Oct 1;305(7):C704-15. doi: 10.1152/ajpcell.00099.2013. Epub 2013 Jun 5.

50.

Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion.

Chen Y, Williams SH, McNulty AL, Hong JH, Lee SH, Rothfusz NE, Parekh PK, Moore C, Gereau RW 4th, Taylor AB, Wang F, Guilak F, Liedtke W.

Pain. 2013 Aug;154(8):1295-304. doi: 10.1016/j.pain.2013.04.004. Epub 2013 Apr 6.

Supplemental Content

Loading ...
Support Center