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Items: 1 to 50 of 122

1.

Human Metabolome Changes after a Single Dose of 3,4-Methylenedioxymethamphetamine (MDMA) with Special Focus on Steroid Metabolism and Inflammation Processes.

Boxler MI, Streun GL, Liechti ME, Schmid Y, Kraemer T, Steuer AE.

J Proteome Res. 2018 Jul 13. doi: 10.1021/acs.jproteome.8b00438. [Epub ahead of print]

PMID:
29947220
2.

Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects.

Vizeli P, Liechti ME.

PLoS One. 2018 Jun 18;13(6):e0199384. doi: 10.1371/journal.pone.0199384. eCollection 2018.

3.

The psychostimulant (±)-cis-4,4'-dimethylaminorex (4,4'-DMAR) interacts with human plasmalemmal and vesicular monoamine transporters.

Maier J, Mayer FP, Luethi D, Holy M, Jäntsch K, Reither H, Hirtler L, Hoener MC, Liechti ME, Pifl C, Brandt SD, Sitte HH.

Neuropharmacology. 2018 Jun 22;138:282-291. doi: 10.1016/j.neuropharm.2018.06.018. [Epub ahead of print]

4.

Monoamine transporter and receptor interaction profiles in vitro predict reported human doses of novel psychoactive stimulants and psychedelics.

Luethi D, Liechti ME.

Int J Neuropsychopharmacol. 2018 May 29. doi: 10.1093/ijnp/pyy047. [Epub ahead of print]

PMID:
29850881
5.

Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances.

Simmler LD, Liechti ME.

Handb Exp Pharmacol. 2018 Apr 10. doi: 10.1007/164_2018_113. [Epub ahead of print]

PMID:
29633178
6.

Altered network hub connectivity after acute LSD administration.

Müller F, Dolder PC, Schmidt A, Liechti ME, Borgwardt S.

Neuroimage Clin. 2018 Mar 7;18:694-701. doi: 10.1016/j.nicl.2018.03.005. eCollection 2018.

7.

Acute effects of lisdexamfetamine and D-amphetamine on social cognition and cognitive performance in a placebo-controlled study in healthy subjects.

Dolder PC, Strajhar P, Vizeli P, Odermatt A, Liechti ME.

Psychopharmacology (Berl). 2018 May;235(5):1389-1402. doi: 10.1007/s00213-018-4849-0. Epub 2018 Feb 9.

PMID:
29511807
8.

Acute recreational drug toxicity: Comparison of self-reports and results of immunoassay and additional analytical methods in a multicenter European case series.

Liakoni E, Yates C, Dines AM, Dargan PI, Heyerdahl F, Hovda KE, Wood DM, Eyer F, Liechti ME; Euro-DEN Plus Research Group.

Medicine (Baltimore). 2018 Feb;97(5):e9784. doi: 10.1097/MD.0000000000009784.

9.

Effects of the new psychoactive substances diclofensine, diphenidine, and methoxphenidine on monoaminergic systems.

Luethi D, Hoener MC, Liechti ME.

Eur J Pharmacol. 2018 Jan 15;819:242-247. doi: 10.1016/j.ejphar.2017.12.012. Epub 2017 Dec 7.

PMID:
29225192
10.

Opioid-induced inhibition of the human 5-HT and noradrenaline transporters in vitro: link to clinical reports of serotonin syndrome.

Rickli A, Liakoni E, Hoener MC, Liechti ME.

Br J Pharmacol. 2018 Feb;175(3):532-543. doi: 10.1111/bph.14105. Epub 2018 Jan 6.

11.

Acute Effects of Methylphenidate, Modafinil, and MDMA on Negative Emotion Processing.

Schmidt A, Müller F, Dolder PC, Schmid Y, Zanchi D, Egloff L, Liechti ME, Borgwardt S.

Int J Neuropsychopharmacol. 2018 Apr 1;21(4):345-354. doi: 10.1093/ijnp/pyx112.

12.

No major role of norepinephrine transporter gene variations in the cardiostimulant effects of MDMA.

Vizeli P, Meyer Zu Schwabedissen HE, Liechti ME.

Eur J Clin Pharmacol. 2018 Mar;74(3):275-283. doi: 10.1007/s00228-017-2392-2. Epub 2017 Dec 2.

13.

Acute LSD effects on response inhibition neural networks.

Schmidt A, Müller F, Lenz C, Dolder PC, Schmid Y, Zanchi D, Lang UE, Liechti ME, Borgwardt S.

Psychol Med. 2018 Jul;48(9):1464-1473. doi: 10.1017/S0033291717002914. Epub 2017 Oct 2.

PMID:
28967351
14.

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects.

Dolder PC, Strajhar P, Vizeli P, Hammann F, Odermatt A, Liechti ME.

Front Pharmacol. 2017 Sep 7;8:617. doi: 10.3389/fphar.2017.00617. eCollection 2017.

15.

Long-lasting subjective effects of LSD in normal subjects.

Schmid Y, Liechti ME.

Psychopharmacology (Berl). 2018 Feb;235(2):535-545. doi: 10.1007/s00213-017-4733-3. Epub 2017 Sep 16.

16.

Pharmacological profile of methylphenidate-based designer drugs.

Luethi D, Kaeser PJ, Brandt SD, Krähenbühl S, Hoener MC, Liechti ME.

Neuropharmacology. 2018 May 15;134(Pt A):133-140. doi: 10.1016/j.neuropharm.2017.08.020. Epub 2017 Aug 18.

PMID:
28823611
17.

Pharmacological profile of mephedrone analogs and related new psychoactive substances.

Luethi D, Kolaczynska KE, Docci L, Krähenbühl S, Hoener MC, Liechti ME.

Neuropharmacology. 2018 May 15;134(Pt A):4-12. doi: 10.1016/j.neuropharm.2017.07.026. Epub 2017 Jul 26.

PMID:
28755886
18.

First Time View on Human Metabolome Changes after a Single Intake of 3,4-Methylenedioxymethamphetamine in Healthy Placebo-Controlled Subjects.

Boxler MI, Liechti ME, Schmid Y, Kraemer T, Steuer AE.

J Proteome Res. 2017 Sep 1;16(9):3310-3320. doi: 10.1021/acs.jproteome.7b00294. Epub 2017 Aug 9.

PMID:
28722422
19.

Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs).

Luethi D, Trachsel D, Hoener MC, Liechti ME.

Neuropharmacology. 2018 May 15;134(Pt A):141-148. doi: 10.1016/j.neuropharm.2017.07.012. Epub 2017 Jul 15.

PMID:
28720478
20.

A Single Dose of LSD Does Not Alter Gene Expression of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects.

Dolder PC, Grünblatt E, Müller F, Borgwardt SJ, Liechti ME.

Front Pharmacol. 2017 Jun 28;8:423. doi: 10.3389/fphar.2017.00423. eCollection 2017.

21.

Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones.

Luethi D, Liechti ME, Krähenbühl S.

Toxicology. 2017 Jul 15;387:57-66. doi: 10.1016/j.tox.2017.06.004. Epub 2017 Jun 20.

PMID:
28645576
22.

Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects.

Dolder PC, Müller F, Schmid Y, Borgwardt SJ, Liechti ME.

Psychopharmacology (Berl). 2018 Feb;235(2):467-479. doi: 10.1007/s00213-017-4650-5. Epub 2017 May 27.

24.

Comparative Effects of Methylphenidate, Modafinil, and MDMA on Response Inhibition Neural Networks in Healthy Subjects.

Schmidt A, Müller F, Dolder PC, Schmid Y, Zanchi D, Liechti ME, Borgwardt S.

Int J Neuropsychopharmacol. 2017 Sep 1;20(9):712-720. doi: 10.1093/ijnp/pyx037.

25.

Modern Clinical Research on LSD.

Liechti ME.

Neuropsychopharmacology. 2017 Oct;42(11):2114-2127. doi: 10.1038/npp.2017.86. Epub 2017 Apr 27. Review.

26.

Safety pharmacology of acute MDMA administration in healthy subjects.

Vizeli P, Liechti ME.

J Psychopharmacol. 2017 May;31(5):576-588. doi: 10.1177/0269881117691569. Epub 2017 Feb 21.

PMID:
28443695
27.

Chiral analysis of amphetamines in hair by liquid chromatography-tandem mass spectrometry: compliance-monitoring of attention deficit hyperactivity disorder (ADHD) patients under Elvanse® therapy and identification after controlled low-dose application.

Binz TM, Williner E, Strajhar P, Dolder PC, Liechti ME, Baumgartner MR, Kraemer T, Steuer AE.

Drug Test Anal. 2018 Feb;10(2):254-261. doi: 10.1002/dta.2208. Epub 2017 Jul 5.

PMID:
28440070
28.

Acute effects of LSD on amygdala activity during processing of fearful stimuli in healthy subjects.

Mueller F, Lenz C, Dolder PC, Harder S, Schmid Y, Lang UE, Liechti ME, Borgwardt S.

Transl Psychiatry. 2017 Apr 4;7(4):e1084. doi: 10.1038/tp.2017.54.

29.

Multifaceted empathy of healthy volunteers after single doses of MDMA: A pooled sample of placebo-controlled studies.

Kuypers KP, Dolder PC, Ramaekers JG, Liechti ME.

J Psychopharmacol. 2017 May;31(5):589-598. doi: 10.1177/0269881117699617. Epub 2017 Apr 3.

30.

Presentations to an urban emergency department in Bern, Switzerland associated with acute recreational drug toxicity.

Liakoni E, Müller S, Stoller A, Ricklin M, Liechti ME, Exadaktylos AK.

Scand J Trauma Resusc Emerg Med. 2017 Mar 7;25(1):26. doi: 10.1186/s13049-017-0369-x.

31.

Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects.

Dolder PC, Schmid Y, Steuer AE, Kraemer T, Rentsch KM, Hammann F, Liechti ME.

Clin Pharmacokinet. 2017 Oct;56(10):1219-1230. doi: 10.1007/s40262-017-0513-9.

32.

The Fabric of Meaning and Subjective Effects in LSD-Induced States Depend on Serotonin 2A Receptor Activation.

Preller KH, Herdener M, Pokorny T, Planzer A, Kraehenmann R, Stämpfli P, Liechti ME, Seifritz E, Vollenweider FX.

Curr Biol. 2017 Feb 6;27(3):451-457. doi: 10.1016/j.cub.2016.12.030. Epub 2017 Jan 26.

33.

Mistaking 2C-P for 2C-B: What a Difference a Letter Makes.

Stoller A, Dolder PC, Bodmer M, Hammann F, Rentsch KM, Exadaktylos AK, Liechti ME, Liakoni E.

J Anal Toxicol. 2017 Jan;41(1):77-79. doi: 10.1093/jat/bkw108. Epub 2016 Oct 6.

PMID:
28130544
34.

Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects.

Vizeli P, Schmid Y, Prestin K, Meyer Zu Schwabedissen HE, Liechti ME.

Eur Neuropsychopharmacol. 2017 Mar;27(3):232-238. doi: 10.1016/j.euroneuro.2017.01.008. Epub 2017 Jan 20.

PMID:
28117133
35.

Alterations of consciousness and mystical-type experiences after acute LSD in humans.

Liechti ME, Dolder PC, Schmid Y.

Psychopharmacology (Berl). 2017 May;234(9-10):1499-1510. doi: 10.1007/s00213-016-4453-0. Epub 2016 Oct 7.

36.

Alcohol acutely enhances decoding of positive emotions and emotional concern for positive stimuli and facilitates the viewing of sexual images.

Dolder PC, Holze F, Liakoni E, Harder S, Schmid Y, Liechti ME.

Psychopharmacology (Berl). 2017 Jan;234(1):41-51. doi: 10.1007/s00213-016-4431-6. Epub 2016 Sep 19.

PMID:
27640999
37.

Presentations to an urban emergency department in Switzerland due to acute γ-hydroxybutyrate toxicity.

Liakoni E, Walther F, Nickel CH, Liechti ME.

Scand J Trauma Resusc Emerg Med. 2016 Aug 31;24(1):107. doi: 10.1186/s13049-016-0299-z.

38.
39.

Interactions of Cathinone NPS with Human Transporters and Receptors in Transfected Cells.

Simmler LD, Liechti ME.

Curr Top Behav Neurosci. 2017;32:49-72. doi: 10.1007/7854_2016_20.

PMID:
27272068
40.

CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of 3,4-methylene-dioxymethamphetamine in a controlled study in healthy individuals.

Schmid Y, Vizeli P, Hysek CM, Prestin K, Meyer Zu Schwabedissen HE, Liechti ME.

Pharmacogenet Genomics. 2016 Aug;26(8):397-401. doi: 10.1097/FPC.0000000000000231.

41.

LSD Acutely Impairs Fear Recognition and Enhances Emotional Empathy and Sociality.

Dolder PC, Schmid Y, Müller F, Borgwardt S, Liechti ME.

Neuropsychopharmacology. 2016 Oct;41(11):2638-46. doi: 10.1038/npp.2016.82. Epub 2016 Jun 1.

42.

Presentations due to acute toxicity of psychoactive substances in an urban emergency department in Switzerland: a case series.

Liakoni E, Dolder PC, Rentsch KM, Liechti ME.

BMC Pharmacol Toxicol. 2016 May 26;17(1):25. doi: 10.1186/s40360-016-0068-7.

43.

Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens.

Rickli A, Moning OD, Hoener MC, Liechti ME.

Eur Neuropsychopharmacol. 2016 Aug;26(8):1327-37. doi: 10.1016/j.euroneuro.2016.05.001. Epub 2016 May 20.

PMID:
27216487
44.

Impact of Cytochrome P450 2D6 Function on the Chiral Blood Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine (MDMA) and Its Phase I and II Metabolites in Humans.

Steuer AE, Schmidhauser C, Tingelhoff EH, Schmid Y, Rickli A, Kraemer T, Liechti ME.

PLoS One. 2016 Mar 11;11(3):e0150955. doi: 10.1371/journal.pone.0150955. eCollection 2016.

45.

Similar and Different? Subjective Effects of Methylphenidate and Cocaine in Opioid-Maintained Patients.

Vogel M, Bucher P, Strasser J, Liechti ME, Krähenbühl S, Dürsteler KM.

J Psychoactive Drugs. 2016 Apr-Jun;48(2):93-100. doi: 10.1080/02791072.2015.1130883. Epub 2016 Mar 3.

PMID:
26940988
46.

Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects.

Strajhar P, Schmid Y, Liakoni E, Dolder PC, Rentsch KM, Kratschmar DV, Odermatt A, Liechti ME.

J Neuroendocrinol. 2016 Mar;28(3):12374. doi: 10.1111/jne.12374.

PMID:
26849997
47.

In Vitro Characterization of Psychoactive Substances at Rat, Mouse, and Human Trace Amine-Associated Receptor 1.

Simmler LD, Buchy D, Chaboz S, Hoener MC, Liechti ME.

J Pharmacol Exp Ther. 2016 Apr;357(1):134-44. doi: 10.1124/jpet.115.229765. Epub 2016 Jan 20.

48.

Neuroimaging in moderate MDMA use: A systematic review.

Mueller F, Lenz C, Steiner M, Dolder PC, Walter M, Lang UE, Liechti ME, Borgwardt S.

Neurosci Biobehav Rev. 2016 Mar;62:21-34. doi: 10.1016/j.neubiorev.2015.12.010. Epub 2015 Dec 30. Review.

49.

Stress-Induced In Vivo Recruitment of Human Cytotoxic Natural Killer Cells Favors Subsets with Distinct Receptor Profiles and Associates with Increased Epinephrine Levels.

Bigler MB, Egli SB, Hysek CM, Hoenger G, Schmied L, Baldin FS, Marquardsen FA, Recher M, Liechti ME, Hess C, Berger CT.

PLoS One. 2015 Dec 23;10(12):e0145635. doi: 10.1371/journal.pone.0145635. eCollection 2015.

50.

Pharmacokinetics and pharmacodynamics of γ-hydroxybutyrate in healthy subjects.

Liechti ME, Quednow BB, Liakoni E, Dornbierer D, von Rotz R, Gachet MS, Gertsch J, Seifritz E, Bosch OG.

Br J Clin Pharmacol. 2016 May;81(5):980-8. doi: 10.1111/bcp.12863. Epub 2016 Feb 25.

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