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Items: 1 to 50 of 106

1.

Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.

Park S, Park SK, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova TA, Liebman SW.

PLoS Genet. 2019 Aug 7;15(8):e1008308. doi: 10.1371/journal.pgen.1008308. eCollection 2019 Aug.

2.

Respiration Enhances TDP-43 Toxicity, but TDP-43 Retains Some Toxicity in the Absence of Respiration.

Park SK, Park S, Liebman SW.

J Mol Biol. 2019 May 3;431(10):2050-2059. doi: 10.1016/j.jmb.2019.03.014. Epub 2019 Mar 21.

PMID:
30905713
3.

Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins.

Park SK, Arslan F, Kanneganti V, Barmada SJ, Purushothaman P, Verma SC, Liebman SW.

Prion. 2018 Jan 2;12(1):16-22. doi: 10.1080/19336896.2017.1423185. Epub 2018 Jan 31.

4.

A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance.

Newby GA, Kiriakov S, Hallacli E, Kayatekin C, Tsvetkov P, Mancuso CP, Bonner JM, Hesse WR, Chakrabortee S, Manogaran AL, Liebman SW, Lindquist S, Khalil AS.

Cell. 2017 Nov 2;171(4):966-979.e18. doi: 10.1016/j.cell.2017.09.041. Epub 2017 Oct 19.

5.

Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis.

Park SK, Hong JY, Arslan F, Kanneganti V, Patel B, Tietsort A, Tank EMH, Li X, Barmada SJ, Liebman SW.

PLoS Genet. 2017 May 22;13(5):e1006805. doi: 10.1371/journal.pgen.1006805. eCollection 2017 May.

6.

Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs.

Park SK, Ratia K, Ba M, Valencik M, Liebman SW.

Microb Cell. 2016 Jan 20;3(2):53-64. doi: 10.15698/mic2016.02.476.

7.

Heterologous aggregates promote de novo prion appearance via more than one mechanism.

Arslan F, Hong JY, Kanneganti V, Park SK, Liebman SW.

PLoS Genet. 2015 Jan 8;11(1):e1004814. doi: 10.1371/journal.pgen.1004814. eCollection 2015 Jan.

8.

Prion-promoted phosphorylation of heterologous amyloid is coupled with ubiquitin-proteasome system inhibition and toxicity.

Yang Z, Stone DE, Liebman SW.

Mol Microbiol. 2014 Sep;93(5):1043-56. doi: 10.1111/mmi.12716. Epub 2014 Aug 5.

9.

Variant-specific prion interactions: Complicating factors.

Sharma J, Liebman SW.

Cell Logist. 2013 Jan 1;3(1):e25698. Epub 2013 Sep 12.

10.

Retrospective. Fred Sherman (1932-2013).

Liebman SW, Haber JE.

Science. 2013 Nov 29;342(6162):1059. doi: 10.1126/science.1248055. No abstract available.

PMID:
24288325
11.

The story of stolen chaperones: how overexpression of Q/N proteins cures yeast prions.

Derkatch IL, Liebman SW.

Prion. 2013 Jul-Aug;7(4):294-300. doi: 10.4161/pri.26021. Epub 2013 Aug 7. Review.

12.

Exploring the basis of [PIN(+)] variant differences in [PSI(+)] induction.

Sharma J, Liebman SW.

J Mol Biol. 2013 Sep 9;425(17):3046-59. doi: 10.1016/j.jmb.2013.06.006. Epub 2013 Jun 14.

13.

Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability.

Yang Z, Hong JY, Derkatch IL, Liebman SW.

PLoS Genet. 2013;9(1):e1003236. doi: 10.1371/journal.pgen.1003236. Epub 2013 Jan 24.

14.

[PSI(+) ] prion variant establishment in yeast.

Sharma J, Liebman SW.

Mol Microbiol. 2012 Nov;86(4):866-81. doi: 10.1111/mmi.12024. Epub 2012 Sep 24.

15.

Prions in yeast.

Liebman SW, Chernoff YO.

Genetics. 2012 Aug;191(4):1041-72. doi: 10.1534/genetics.111.137760. Review.

16.

Localization of HET-S to the cell periphery, not to [Het-s] aggregates, is associated with [Het-s]-HET-S toxicity.

Mathur V, Seuring C, Riek R, Saupe SJ, Liebman SW.

Mol Cell Biol. 2012 Jan;32(1):139-53. doi: 10.1128/MCB.06125-11. Epub 2011 Oct 28.

17.

Development and validation of a yeast high-throughput screen for inhibitors of Aβ₄₂ oligomerization.

Park SK, Pegan SD, Mesecar AD, Jungbauer LM, LaDu MJ, Liebman SW.

Dis Model Mech. 2011 Nov;4(6):822-31. doi: 10.1242/dmm.007963. Epub 2011 Aug 2.

18.

Prion induction by the short-lived, stress-induced protein Lsb2 is regulated by ubiquitination and association with the actin cytoskeleton.

Chernova TA, Romanyuk AV, Karpova TS, Shanks JR, Ali M, Moffatt N, Howie RL, O'Dell A, McNally JG, Liebman SW, Chernoff YO, Wilkinson KD.

Mol Cell. 2011 Jul 22;43(2):242-52. doi: 10.1016/j.molcel.2011.07.001.

19.

Prion formation and polyglutamine aggregation are controlled by two classes of genes.

Manogaran AL, Hong JY, Hufana J, Tyedmers J, Lindquist S, Liebman SW.

PLoS Genet. 2011 May;7(5):e1001386. doi: 10.1371/journal.pgen.1001386. Epub 2011 May 19.

20.

A new colour assay for [URE3] prion in a genetic background used to score for the [PSI⁺] prion.

Hong JY, Mathur V, Liebman SW.

Yeast. 2011 Jul;28(7):555-60. doi: 10.1002/yea.1857. Epub 2011 May 18.

21.

Prions and amyloids--an overview.

Liebman SW.

Semin Cell Dev Biol. 2011 Jul;22(5):435-6. doi: 10.1016/j.semcdb.2011.04.001. Epub 2011 Apr 9. No abstract available.

PMID:
21501691
22.

Analyzing the birth and propagation of two distinct prions, [PSI+] and [Het-s](y), in yeast.

Mathur V, Taneja V, Sun Y, Liebman SW.

Mol Biol Cell. 2010 May 1;21(9):1449-61. doi: 10.1091/mbc.E09-11-0927. Epub 2010 Mar 10.

23.

Protein folding: sticky N17 speeds huntingtin pile-up.

Liebman SW, Meredith SC.

Nat Chem Biol. 2010 Jan;6(1):7-8. doi: 10.1038/nchembio.279. No abstract available.

PMID:
20016493
24.

Most, but not all, yeast strains in the deletion library contain the [PIN(+)] prion.

Manogaran AL, Fajardo VM, Reid RJ, Rothstein R, Liebman SW.

Yeast. 2010 Mar;27(3):159-66. doi: 10.1002/yea.1740.

25.

Sequestration of essential proteins causes prion associated toxicity in yeast.

Vishveshwara N, Bradley ME, Liebman SW.

Mol Microbiol. 2009 Sep;73(6):1101-14. doi: 10.1111/j.1365-2958.2009.06836.x. Epub 2009 Aug 11.

26.

Heterologous cross-seeding mimics cross-species prion conversion in a yeast model.

Vishveshwara N, Liebman SW.

BMC Biol. 2009 May 26;7:26. doi: 10.1186/1741-7007-7-26.

27.

Ssa1 overexpression and [PIN(+)] variants cure [PSI(+)] by dilution of aggregates.

Mathur V, Hong JY, Liebman SW.

J Mol Biol. 2009 Jul 10;390(2):155-67. doi: 10.1016/j.jmb.2009.04.063. Epub 2009 May 5.

28.

The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion.

Patel BK, Gavin-Smyth J, Liebman SW.

Nat Cell Biol. 2009 Mar;11(3):344-9. doi: 10.1038/ncb1843. Epub 2009 Feb 15.

29.

Variant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterogeneous protein composition.

Bagriantsev SN, Gracheva EO, Richmond JE, Liebman SW.

Mol Biol Cell. 2008 Jun;19(6):2433-43. doi: 10.1091/mbc.E08-01-0078. Epub 2008 Mar 19.

30.

A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast.

Taneja V, Maddelein ML, Talarek N, Saupe SJ, Liebman SW.

Mol Cell. 2007 Jul 6;27(1):67-77.

31.

Prion-prion interactions.

Derkatch IL, Liebman SW.

Prion. 2007 Jul-Sep;1(3):161-9. Epub 2007 Jul 6. Review.

32.

Propagation of the [PIN+] prion by fragments of Rnq1 fused to GFP.

Vitrenko YA, Pavon ME, Stone SI, Liebman SW.

Curr Genet. 2007 May;51(5):309-19. Epub 2007 Apr 6.

33.

Visualization of aggregation of the Rnq1 prion domain and cross-seeding interactions with Sup35NM.

Vitrenko YA, Gracheva EO, Richmond JE, Liebman SW.

J Biol Chem. 2007 Jan 19;282(3):1779-87. Epub 2006 Nov 22.

34.
35.

Analysis of amyloid aggregates using agarose gel electrophoresis.

Bagriantsev SN, Kushnirov VV, Liebman SW.

Methods Enzymol. 2006;412:33-48. Review.

PMID:
17046650
36.

Biochemical and genetic methods for characterization of [PIN+] prions in yeast.

Liebman SW, Bagriantsev SN, Derkatch IL.

Methods. 2006 May;39(1):23-34.

PMID:
16793281
38.

Tracking the elusive prion.

Liebman SW, Mastrianni JA.

Trends Mol Med. 2005 Oct;11(10):439-41. Review.

PMID:
16150640
39.

Structural clues to prion mysteries.

Liebman SW.

Nat Struct Mol Biol. 2005 Jul;12(7):567-8. No abstract available.

PMID:
15999110
40.

Specificity of prion assembly in vivo. [PSI+] and [PIN+] form separate structures in yeast.

Bagriantsev S, Liebman SW.

J Biol Chem. 2004 Dec 3;279(49):51042-8. Epub 2004 Sep 30.

41.

Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro.

Derkatch IL, Uptain SM, Outeiro TF, Krishnan R, Lindquist SL, Liebman SW.

Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12934-9. Epub 2004 Aug 23.

42.
43.

Destabilizing interactions among [PSI(+)] and [PIN(+)] yeast prion variants.

Bradley ME, Liebman SW.

Genetics. 2003 Dec;165(4):1675-85. Erratum in: Genetics. 2011 Aug;188(4):1023.

44.

Guanidine reduces stop codon read-through caused by missense mutations in SUP35 or SUP45.

Bradley ME, Bagriantsev S, Vishveshwara N, Liebman SW.

Yeast. 2003 May;20(7):625-32.

45.

Interactions among prions and prion "strains" in yeast.

Bradley ME, Edskes HK, Hong JY, Wickner RB, Liebman SW.

Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4:16392-9. Epub 2002 Jul 30.

46.

Progress toward an ultimate proof of the prion hypothesis.

Liebman SW.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9098-100. Epub 2002 Jul 1. No abstract available.

47.

Prions affect the appearance of other prions: the story of [PIN(+)].

Derkatch IL, Bradley ME, Hong JY, Liebman SW.

Cell. 2001 Jul 27;106(2):171-82.

48.

Prions. The shape of a species barrier.

Liebman SW.

Nature. 2001 Mar 8;410(6825):161-2. No abstract available.

PMID:
11258377
49.

Genetic interaction between yeast Saccharomyces cerevisiae release factors and the decoding region of 18 S rRNA.

Velichutina IV, Hong JY, Mesecar AD, Chernoff YO, Liebman SW.

J Mol Biol. 2001 Jan 26;305(4):715-27.

PMID:
11162087

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