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Items: 1 to 50 of 101

1.

Loss of Gadd45b accelerates BCR-ABL-driven CML.

Sha X, Hoffman B, Liebermann DA.

Oncotarget. 2018 Sep 7;9(70):33360-33367. doi: 10.18632/oncotarget.26076. eCollection 2018 Sep 7.

2.

Loss of Egr1, a human del5q gene, accelerates BCR-ABL driven chronic myelogenous leukemia.

Maifrede S, Magimaidas A, Sha X, Mukherjee K, Liebermann DA, Hoffman B.

Oncotarget. 2017 Sep 1;8(41):69281-69294. doi: 10.18632/oncotarget.20612. eCollection 2017 Sep 19.

3.

Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia.

Mukherjee K, Sha X, Magimaidas A, Maifrede S, Skorski T, Bhatia R, Hoffman B, Liebermann DA.

Oncotarget. 2017 Feb 14;8(7):10809-10821. doi: 10.18632/oncotarget.14580.

4.

First trimester noninvasive fetal RHD genotyping using maternal dried blood spots.

Xiong Y, Jeronis S, Hoffman B, Liebermann DA, Geifman-Holtzman O.

Prenat Diagn. 2017 Apr;37(4):311-317. doi: 10.1002/pd.5006. Epub 2017 Mar 6.

PMID:
28081297
5.

Gadd45b deficiency promotes premature senescence and skin aging.

Magimaidas A, Madireddi P, Maifrede S, Mukherjee K, Hoffman B, Liebermann DA.

Oncotarget. 2016 May 10;7(19):26935-48. doi: 10.18632/oncotarget.8854.

6.

Gadd45 in modulation of solid tumors and leukemia.

Hoffman B, Liebermann DA.

Adv Exp Med Biol. 2013;793:21-33. doi: 10.1007/978-1-4614-8289-5_2. Review.

PMID:
24104471
7.

Gadd45a levels in human breast cancer are hormone receptor dependent.

Tront JS, Willis A, Huang Y, Hoffman B, Liebermann DA.

J Transl Med. 2013 May 24;11:131. doi: 10.1186/1479-5876-11-131.

8.

Genetic deletion of Gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity.

Sultan FA, Wang J, Tront J, Liebermann DA, Sweatt JD.

J Neurosci. 2012 Nov 28;32(48):17059-66. doi: 10.1523/JNEUROSCI.1747-12.2012.

9.

Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.

Keil E, Höcker R, Schuster M, Essmann F, Ueffing N, Hoffman B, Liebermann DA, Pfeffer K, Schulze-Osthoff K, Schmitz I.

Cell Death Differ. 2013 Feb;20(2):321-32. doi: 10.1038/cdd.2012.129. Epub 2012 Oct 12.

10.

Gadd45b knockout mice exhibit selective deficits in hippocampus-dependent long-term memory.

Leach PT, Poplawski SG, Kenney JW, Hoffman B, Liebermann DA, Abel T, Gould TJ.

Learn Mem. 2012 Jul 16;19(8):319-24. doi: 10.1101/lm.024984.111.

11.

Preeclampsia-associated stresses activate Gadd45a signaling and sFlt-1 in placental explants.

Xiong Y, Liebermann DA, Holtzman EJ, Jeronis S, Hoffman B, Geifman-Holtzman O.

J Cell Physiol. 2013 Feb;228(2):362-70. doi: 10.1002/jcp.24139.

PMID:
22718299
12.

Gadd45a and Gadd45b modulate innate immune functions of granulocytes and macrophages by differential regulation of p38 and JNK signaling.

Salerno DM, Tront JS, Hoffman B, Liebermann DA.

J Cell Physiol. 2012 Nov;227(11):3613-20. doi: 10.1002/jcp.24067.

PMID:
22307729
13.

Gadd45 stress sensors in malignancy and leukemia.

Liebermann DA, Tront JS, Sha X, Mukherjee K, Mohamed-Hadley A, Hoffman B.

Crit Rev Oncog. 2011;16(1-2):129-40. Review.

14.

Prostate cancer: JunD, Gadd45a and Gadd45g as therapeutic targets.

Liebermann DA, Hoffman B.

Cell Cycle. 2011 Oct 15;10(20):3428. doi: 10.4161/cc.10.20.17528. Epub 2011 Oct 15. No abstract available.

PMID:
22030693
15.

Gadd45β is an inducible coactivator of transcription that facilitates rapid liver growth in mice.

Tian J, Huang H, Hoffman B, Liebermann DA, Ledda-Columbano GM, Columbano A, Locker J.

J Clin Invest. 2011 Nov;121(11):4491-502. doi: 10.1172/JCI38760. Epub 2011 Oct 3.

16.

Gadd45a functions as a promoter or suppressor of breast cancer dependent on the oncogenic stress.

Tront JS, Huang Y, Fornace AJ Jr, Hoffman B, Liebermann DA.

Cancer Res. 2010 Dec 1;70(23):9671-81. doi: 10.1158/0008-5472.CAN-10-2177. Epub 2010 Nov 23. Erratum in: Cancer Res. 2011 Feb 15;71(4):1506. Fornace, Albert A Jr [corrected to Fornace, Albert J Jr].

17.

Increased placental telomerase mRNA in hypertensive disorders of pregnancy.

Geifman-Holtzman O, Xiong Y, Holtzman EJ, Hoffman B, Gaughan J, Liebermann DA.

Hypertens Pregnancy. 2010;29(4):434-45. doi: 10.3109/10641950903214625.

18.

Distinct mechanisms are utilized to induce stress sensor gadd45b by different stress stimuli.

Zumbrun SD, Hoffman B, Liebermann DA.

J Cell Biochem. 2009 Dec 1;108(5):1220-31. doi: 10.1002/jcb.22354.

PMID:
19834918
19.

Stress sensor Gadd45 genes as therapeutic targets in cancer.

Cretu A, Sha X, Tront J, Hoffman B, Liebermann DA.

Cancer Ther. 2009;7(A):268-276.

20.

Gadd45a stress signaling regulates sFlt-1 expression in preeclampsia.

Xiong Y, Liebermann DA, Tront JS, Holtzman EJ, Huang Y, Hoffman B, Geifman-Holtzman O.

J Cell Physiol. 2009 Sep;220(3):632-9. doi: 10.1002/jcp.21800.

PMID:
19452502
21.

Good and bad IRF-1: role in tumor suppression versus autoimmune disease.

Liebermann DA, Hoffman B.

Leuk Res. 2009 Oct;33(10):1301-2. doi: 10.1016/j.leukres.2009.03.038. Epub 2009 May 12. No abstract available.

PMID:
19439353
22.

Conserved DNA methylation in Gadd45a(-/-) mice.

Engel N, Tront JS, Erinle T, Nguyen N, Latham KE, Sapienza C, Hoffman B, Liebermann DA.

Epigenetics. 2009 Feb 16;4(2):98-9. Epub 2009 Feb 15.

23.

Apoptotic signaling by c-MYC.

Hoffman B, Liebermann DA.

Oncogene. 2008 Oct 27;27(50):6462-72. doi: 10.1038/onc.2008.312. Review.

PMID:
18955973
24.

Gadd45 in stress signaling.

Liebermann DA, Hoffman B.

J Mol Signal. 2008 Sep 12;3:15. doi: 10.1186/1750-2187-3-15.

25.

Gadd45 modulation of intrinsic and extrinsic stress responses in myeloid cells.

Hoffman B, Liebermann DA.

J Cell Physiol. 2009 Jan;218(1):26-31. doi: 10.1002/jcp.21582. Review.

PMID:
18780287
26.

Leukemia suppressor function of Egr-1 is dependent on transforming oncogene.

Gibbs JD, Liebermann DA, Hoffman B.

Leukemia. 2008 Oct;22(10):1909-16. doi: 10.1038/leu.2008.189. Epub 2008 Jul 24.

PMID:
18650844
27.

Role of gadd45 in myeloid cells in response to hematopoietic stress.

Hoffman B, Liebermann DA.

Blood Cells Mol Dis. 2007 Nov-Dec;39(3):344-7. Epub 2007 Aug 7. Review.

28.

Gadd45 in the response of hematopoietic cells to genotoxic stress.

Liebermann DA, Hoffman B.

Blood Cells Mol Dis. 2007 Nov-Dec;39(3):329-35. Epub 2007 Jul 30. Review.

29.

Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia.

Gibbs JD, Liebermann DA, Hoffman B.

Oncogene. 2008 Jan 3;27(1):98-106. Epub 2007 Jun 25.

PMID:
17599039
30.

Terminal myeloid differentiation is uncoupled from cell cycle arrest.

Gibbs JD, Liebermann DA, Hoffman B.

Cell Cycle. 2007 May 15;6(10):1205-9. Epub 2007 May 4.

PMID:
17495532
31.

p53 induced growth arrest versus apoptosis and its modulation by survival cytokines.

Liebermann DA, Hoffman B, Vesely D.

Cell Cycle. 2007 Jan 15;6(2):166-70. Epub 2007 Jan 29. Review.

PMID:
17264673
32.

Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cells.

Vesely DL, Hoffman B, Liebermann DA.

Oncogene. 2007 May 10;26(21):3041-50. Epub 2006 Nov 13.

PMID:
17099722
33.

Gadd45a suppresses Ras-driven mammary tumorigenesis by activation of c-Jun NH2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence.

Tront JS, Hoffman B, Liebermann DA.

Cancer Res. 2006 Sep 1;66(17):8448-54. Erratum in: Cancer Res. 2007 Jan 1;67(1):427.

34.
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36.

Interferon regulatory factor-1 myelodysplasia and leukemia.

Liebermann DA, Hoffman B.

Leuk Res. 2006 Sep;30(9):1069-71. Epub 2006 Apr 18. Review. No abstract available.

PMID:
16620966
37.

Myeloid progenitors on demand.

Liebermann DA, Hoffman B.

Nat Methods. 2006 Apr;3(4):248-9. No abstract available.

PMID:
16554827
38.

Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis.

Gupta M, Gupta SK, Balliet AG, Hollander MC, Fornace AJ, Hoffman B, Liebermann DA.

Oncogene. 2005 Nov 3;24(48):7170-9.

PMID:
16170381
39.

Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation.

Shafarenko M, Liebermann DA, Hoffman B.

Blood. 2005 Aug 1;106(3):871-8. Epub 2005 Apr 19.

40.

Fos modulates myeloid cell survival and differentiation and partially abrogates the c-Myc block in terminal myeloid differentiation.

Shafarenko M, Amanullah A, Gregory B, Liebermann DA, Hoffman B.

Blood. 2004 Jun 1;103(11):4259-67. Epub 2004 Feb 24.

PMID:
14982872
41.

Myeloid differentiation (MyD) primary response genes in hematopoiesis.

Liebermann DA, Hoffman B.

Blood Cells Mol Dis. 2003 Sep-Oct;31(2):213-28. Review.

PMID:
12972029
42.

Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation.

Yoo J, Ghiassi M, Jirmanova L, Balliet AG, Hoffman B, Fornace AJ Jr, Liebermann DA, Bottinger EP, Roberts AB.

J Biol Chem. 2003 Oct 31;278(44):43001-7. Epub 2003 Aug 21.

43.

Comparative analysis of the genetic structure and chromosomal mapping of the murine Gadd45g/CR6 gene.

Balliet AG, Hollander MC, Fornace AJ Jr, Hoffman B, Liebermann DA.

DNA Cell Biol. 2003 Jul;22(7):457-68.

PMID:
12932304
44.

Activation of the Jak3 pathway is associated with granulocytic differentiation of myeloid precursor cells.

Rane SG, Mangan JK, Amanullah A, Wong BC, Vora RK, Liebermann DA, Hoffman B, Graña X, Reddy EP.

Blood. 2002 Oct 15;100(8):2753-62.

PMID:
12351382
45.

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress.

Vairapandi M, Balliet AG, Hoffman B, Liebermann DA.

J Cell Physiol. 2002 Sep;192(3):327-38.

PMID:
12124778
46.
47.

The proto-oncogene c-myc in hematopoietic development and leukemogenesis.

Hoffman B, Amanullah A, Shafarenko M, Liebermann DA.

Oncogene. 2002 May 13;21(21):3414-21. Review.

48.

Myeloid differentiation (MyD) primary response genes in hematopoiesis.

Liebermann DA, Hoffman B.

Oncogene. 2002 May 13;21(21):3391-402. Review.

49.
50.

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