Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 162

1.

ARID1A promotes genomic stability through protecting telomere cohesion.

Zhao B, Lin J, Rong L, Wu S, Deng Z, Fatkhutdinov N, Zundell J, Fukumoto T, Liu Q, Kossenkov A, Jean S, Cadungog MG, Borowsky ME, Drapkin R, Lieberman PM, Abate-Shen CT, Zhang R.

Nat Commun. 2019 Sep 6;10(1):4067. doi: 10.1038/s41467-019-12037-4.

2.

ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization.

Li F, Deng Z, Zhang L, Wu C, Jin Y, Hwang I, Vladimirova O, Xu L, Yang L, Lu B, Dheekollu J, Li JY, Feng H, Hu J, Vakoc CR, Ying H, Paik J, Lieberman PM, Zheng H.

EMBO J. 2019 Oct 1;38(19):e96659. doi: 10.15252/embj.201796659. Epub 2019 Aug 27.

PMID:
31454099
3.

Correction: Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.

Dheekollu J, Malecka K, Wiedmer A, Delecluse HJ, Chiang AKS, Altieri DC, Messick TE, Lieberman PM.

Oncotarget. 2019 Jul 8;10(43):4505-4506. doi: 10.18632/oncotarget.27073. eCollection 2019 Jul 8.

4.

Development of a novel inducer for EBV lytic therapy.

Tikhmyanova N, Paparoidamis N, Romero-Masters J, Feng X, Mohammed FS, Reddy PAN, Kenney SC, Lieberman PM, Salvino JM.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2259-2264. doi: 10.1016/j.bmcl.2019.06.034. Epub 2019 Jun 22.

PMID:
31255485
5.

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53.

Tutton S, Deng Z, Gulve N, Vladimirova O, Beishline K, Wiedmer A, Murphy M, Lieberman PM.

Oncotarget. 2019 Jun 4;10(38):3581-3591. doi: 10.18632/oncotarget.26980. eCollection 2019 Jun 4.

6.

Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.

Malecka KA, Dheekollu J, Deakyne JS, Wiedmer A, Ramirez UD, Lieberman PM, Messick TE.

J Virol. 2019 Sep 30;93(20). pii: e00487-19. doi: 10.1128/JVI.00487-19. Print 2019 Oct 15.

PMID:
31142669
7.

Fatty acid transport protein 2 reprograms neutrophils in cancer.

Veglia F, Tyurin VA, Blasi M, De Leo A, Kossenkov AV, Donthireddy L, To TKJ, Schug Z, Basu S, Wang F, Ricciotti E, DiRusso C, Murphy ME, Vonderheide RH, Lieberman PM, Mulligan C, Nam B, Hockstein N, Masters G, Guarino M, Lin C, Nefedova Y, Black P, Kagan VE, Gabrilovich DI.

Nature. 2019 May;569(7754):73-78. doi: 10.1038/s41586-019-1118-2. Epub 2019 Apr 17.

PMID:
30996346
8.

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.

Messick TE, Smith GR, Soldan SS, McDonnell ME, Deakyne JS, Malecka KA, Tolvinski L, van den Heuvel APJ, Gu BW, Cassel JA, Tran DH, Wassermann BR, Zhang Y, Velvadapu V, Zartler ER, Busson P, Reitz AB, Lieberman PM.

Sci Transl Med. 2019 Mar 6;11(482). pii: eaau5612. doi: 10.1126/scitranslmed.aau5612.

PMID:
30842315
9.

PML is recruited to heterochromatin during S phase and represses DAXX-mediated histone H3.3 chromatin assembly.

Shastrula PK, Sierra I, Deng Z, Keeney F, Hayden JE, Lieberman PM, Janicki SM.

J Cell Sci. 2019 Mar 26;132(6). pii: jcs220970. doi: 10.1242/jcs.220970.

10.

LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency.

De Leo A, Deng Z, Vladimirova O, Chen HS, Dheekollu J, Calderon A, Myers KA, Hayden J, Keeney F, Kaufer BB, Yuan Y, Robertson E, Lieberman PM.

PLoS Pathog. 2019 Jan 25;15(1):e1007489. doi: 10.1371/journal.ppat.1007489. eCollection 2019 Jan.

11.

Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma.

Reyes-Uribe P, Adrianzen-Ruesta MP, Deng Z, Echevarria-Vargas I, Mender I, Saheb S, Liu Q, Altieri DC, Murphy ME, Shay JW, Lieberman PM, Villanueva J.

Oncogene. 2018 Jul;37(30):4058-4072. doi: 10.1038/s41388-018-0247-7. Epub 2018 Apr 26.

12.

Correction: Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage.

De Leo A, Chen HS, Hu CA, Lieberman PM.

PLoS Pathog. 2018 Apr 25;14(4):e1007027. doi: 10.1371/journal.ppat.1007027. eCollection 2018 Apr.

13.

Lymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2.

AlQarni S, Al-Sheikh Y, Campbell D, Drotar M, Hannigan A, Boyle S, Herzyk P, Kossenkov A, Armfield K, Jamieson L, Bailo M, Lieberman PM, Tsimbouri P, Wilson JB.

Oncogene. 2018 Jul;37(29):3998-4012. doi: 10.1038/s41388-018-0147-x. Epub 2018 Apr 25.

14.

TERRA and the histone methyltransferase Dot1 cooperate to regulate senescence in budding yeast.

Wanat JJ, Logsdon GA, Driskill JH, Deng Z, Lieberman PM, Johnson FB.

PLoS One. 2018 Apr 12;13(4):e0195698. doi: 10.1371/journal.pone.0195698. eCollection 2018.

15.

CTCF-Induced Circular DNA Complexes Observed by Atomic Force Microscopy.

Mawhinney MT, Liu R, Lu F, Maksimoska J, Damico K, Marmorstein R, Lieberman PM, Urbanc B.

J Mol Biol. 2018 Mar 16;430(6):759-776. doi: 10.1016/j.jmb.2018.01.012. Epub 2018 Jan 31.

16.

RNA-Seq of Kaposi's sarcoma reveals alterations in glucose and lipid metabolism.

Tso FY, Kossenkov AV, Lidenge SJ, Ngalamika O, Ngowi JR, Mwaiselage J, Wickramasinghe J, Kwon EH, West JT, Lieberman PM, Wood C.

PLoS Pathog. 2018 Jan 19;14(1):e1006844. doi: 10.1371/journal.ppat.1006844. eCollection 2018 Jan.

17.

CTCF driven TERRA transcription facilitates completion of telomere DNA replication.

Beishline K, Vladimirova O, Tutton S, Wang Z, Deng Z, Lieberman PM.

Nat Commun. 2017 Dec 13;8(1):2114. doi: 10.1038/s41467-017-02212-w.

18.

Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes.

Shastrula PK, Rice CT, Wang Z, Lieberman PM, Skordalakes E.

Nucleic Acids Res. 2018 Jan 25;46(2):972-984. doi: 10.1093/nar/gkx1213.

19.

Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage.

De Leo A, Chen HS, Hu CC, Lieberman PM.

PLoS Pathog. 2017 Aug 30;13(8):e1006596. doi: 10.1371/journal.ppat.1006596. eCollection 2017 Aug. Erratum in: PLoS Pathog. 2018 Apr 25;14 (4):e1007027.

20.

Coordinate Regulation of TET2 and EBNA2 Controls the DNA Methylation State of Latent Epstein-Barr Virus.

Lu F, Wiedmer A, Martin KA, Wickramasinghe PJMS, Kossenkov AV, Lieberman PM.

J Virol. 2017 Sep 27;91(20). pii: e00804-17. doi: 10.1128/JVI.00804-17. Print 2017 Oct 15.

21.

The Telomeric Response to Viral Infection.

Wang Z, Deng Z, Tutton S, Lieberman PM.

Viruses. 2017 Aug 9;9(8). pii: E218. doi: 10.3390/v9080218. Review.

22.

DNA hypermethylation induced by Epstein-Barr virus in the development of Epstein-Barr virus-associated gastric carcinoma.

Choi SJ, Shin YS, Kang BW, Kim JG, Won KJ, Lieberman PM, Cho H, Kang H.

Arch Pharm Res. 2017 Aug;40(8):894-905. doi: 10.1007/s12272-017-0939-5. Epub 2017 Aug 4. Review.

PMID:
28779374
23.

Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation.

Tikhmyanova N, Tutton S, Martin KA, Lu F, Kossenkov AV, Paparoidamis N, Kenney S, Salvino JM, Lieberman PM.

PLoS Pathog. 2017 Jul 17;13(7):e1006517. doi: 10.1371/journal.ppat.1006517. eCollection 2017 Jul.

24.

Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance.

Deakyne JS, Malecka KA, Messick TE, Lieberman PM.

J Virol. 2017 Sep 12;91(19). pii: e01046-17. doi: 10.1128/JVI.01046-17. Print 2017 Oct 1.

25.

BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency.

Chen HS, De Leo A, Wang Z, Kerekovic A, Hills R, Lieberman PM.

PLoS Pathog. 2017 Jan 20;13(1):e1006100. doi: 10.1371/journal.ppat.1006100. eCollection 2017 Jan.

26.

Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.

Dheekollu J, Malecka K, Wiedmer A, Delecluse HJ, Chiang AK, Altieri DC, Messick TE, Lieberman PM.

Oncotarget. 2017 Jan 31;8(5):7248-7264. doi: 10.18632/oncotarget.14540. Erratum in: Oncotarget. 2019 Jul 08;10(43):4505-4506.

27.

CTCF interacts with the lytic HSV-1 genome to promote viral transcription.

Lang F, Li X, Vladimirova O, Hu B, Chen G, Xiao Y, Singh V, Lu D, Li L, Han H, Wickramasinghe JM, Smith ST, Zheng C, Li Q, Lieberman PM, Fraser NW, Zhou J.

Sci Rep. 2017 Jan 3;7:39861. doi: 10.1038/srep39861.

28.

Identification of Small-Molecule PHD2 Zinc Finger Inhibitors that Activate Hypoxia Inducible Factor.

Arsenault PR, Song D, Bergkamp M, Ravaschiere AM, Navalsky BE, Lieberman PM, Lee FS.

Chembiochem. 2016 Dec 14;17(24):2316-2323. doi: 10.1002/cbic.201600493. Epub 2016 Nov 11.

29.

Structural basis underlying viral hijacking of a histone chaperone complex.

Huang H, Deng Z, Vladimirova O, Wiedmer A, Lu F, Lieberman PM, Patel DJ.

Nat Commun. 2016 Sep 1;7:12707. doi: 10.1038/ncomms12707.

30.

Retrotransposon-derived p53 binding sites enhance telomere maintenance and genome protection.

Lieberman PM.

Bioessays. 2016 Oct;38(10):943-9. doi: 10.1002/bies.201600078. Epub 2016 Aug 19. Review.

31.

Getting Back to the Basics of Translational Research.

Lieberman PM.

PLoS Pathog. 2016 Jul 21;12(7):e1005534. doi: 10.1371/journal.ppat.1005534. eCollection 2016 Jul. No abstract available.

32.

The crosstalk of telomere dysfunction and inflammation through cell-free TERRA containing exosomes.

Wang Z, Lieberman PM.

RNA Biol. 2016 Aug 2;13(8):690-5. doi: 10.1080/15476286.2016.1203503. Epub 2016 Jun 28. Review.

33.

Epigenetics and Genetics of Viral Latency.

Lieberman PM.

Cell Host Microbe. 2016 May 11;19(5):619-28. doi: 10.1016/j.chom.2016.04.008. Review.

34.

Computational analysis of EBNA1 "druggability" suggests novel insights for Epstein-Barr virus inhibitor design.

Gianti E, Messick TE, Lieberman PM, Zauhar RJ.

J Comput Aided Mol Des. 2016 Apr;30(4):285-303. doi: 10.1007/s10822-016-9899-y. Epub 2016 Apr 5.

35.

HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus.

Dheekollu J, Wiedmer A, Sentana-Lledo D, Cassel J, Messick T, Lieberman PM.

J Virol. 2016 May 12;90(11):5353-5367. doi: 10.1128/JVI.00239-16. Print 2016 Jun 1.

36.

A role for p53 in telomere protection.

Tutton S, Lieberman PM.

Mol Cell Oncol. 2016 Feb 18;4(6):e1143078. doi: 10.1080/23723556.2016.1143078. eCollection 2017.

37.

EBNA2 Drives Formation of New Chromosome Binding Sites and Target Genes for B-Cell Master Regulatory Transcription Factors RBP-jκ and EBF1.

Lu F, Chen HS, Kossenkov AV, DeWispeleare K, Won KJ, Lieberman PM.

PLoS Pathog. 2016 Jan 11;12(1):e1005339. doi: 10.1371/journal.ppat.1005339. eCollection 2016 Jan.

38.

Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres.

Tutton S, Azzam GA, Stong N, Vladimirova O, Wiedmer A, Monteith JA, Beishline K, Wang Z, Deng Z, Riethman H, McMahon SB, Murphy M, Lieberman PM.

EMBO J. 2016 Jan 18;35(2):193-207. doi: 10.15252/embj.201490880. Epub 2015 Dec 12.

39.

Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.

Wang Z, Deng Z, Dahmane N, Tsai K, Wang P, Williams DR, Kossenkov AV, Showe LC, Zhang R, Huang Q, Conejo-Garcia JR, Lieberman PM.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6293-300. doi: 10.1073/pnas.1505962112. Epub 2015 Nov 2.

40.

Identification of MEF2B, EBF1, and IL6R as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte Survival.

Tempera I, De Leo A, Kossenkov AV, Cesaroni M, Song H, Dawany N, Showe L, Lu F, Wikramasinghe P, Lieberman PM.

J Virol. 2015 Oct 14;90(1):345-55. doi: 10.1128/JVI.02318-15. Print 2016 Jan 1.

41.

Chromatin Structure of Epstein-Barr Virus Latent Episomes.

Lieberman PM.

Curr Top Microbiol Immunol. 2015;390(Pt 1):71-102. doi: 10.1007/978-3-319-22822-8_5. Review.

PMID:
26424644
42.

Inhibition of autophagy in EBV-positive Burkitt's lymphoma cells enhances EBV lytic genes expression and replication.

De Leo A, Colavita F, Ciccosanti F, Fimia GM, Lieberman PM, Mattia E.

Cell Death Dis. 2015 Sep 3;6:e1876. doi: 10.1038/cddis.2015.156.

43.

Disruption of host antiviral resistances by gammaherpesvirus tegument proteins with homology to the FGARAT purine biosynthesis enzyme.

Tsai K, Messick TE, Lieberman PM.

Curr Opin Virol. 2015 Oct;14:30-40. doi: 10.1016/j.coviro.2015.07.008. Epub 2015 Aug 7. Review.

44.

HSV-1 remodels host telomeres to facilitate viral replication.

Deng Z, Kim ET, Vladimirova O, Dheekollu J, Wang Z, Newhart A, Liu D, Myers JL, Hensley SE, Moffat J, Janicki SM, Fraser NW, Knipe DM, Weitzman MD, Lieberman PM.

Cell Rep. 2014 Dec 24;9(6):2263-78. doi: 10.1016/j.celrep.2014.11.019. Epub 2014 Dec 11.

45.

Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection.

Tsai K, Chan L, Gibeault R, Conn K, Dheekollu J, Domsic J, Marmorstein R, Schang LM, Lieberman PM.

J Virol. 2014 Dec;88(24):14350-63. doi: 10.1128/JVI.01895-14. Epub 2014 Oct 1.

46.

CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication.

Martínez FP, Cruz R, Lu F, Plasschaert R, Deng Z, Rivera-Molina YA, Bartolomei MS, Lieberman PM, Tang Q.

J Virol. 2014 Jul;88(13):7389-401. doi: 10.1128/JVI.00845-14. Epub 2014 Apr 16.

47.

Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline.

Stong N, Deng Z, Gupta R, Hu S, Paul S, Weiner AK, Eichler EE, Graves T, Fronick CC, Courtney L, Wilson RK, Lieberman PM, Davuluri RV, Riethman H.

Genome Res. 2014 Jun;24(6):1039-50. doi: 10.1101/gr.166983.113. Epub 2014 Mar 27.

48.

Virology. Epstein-Barr virus turns 50.

Lieberman PM.

Science. 2014 Mar 21;343(6177):1323-5. doi: 10.1126/science.1252786. No abstract available.

49.

Adenovirus-based vaccines against rhesus lymphocryptovirus EBNA-1 induce expansion of specific CD8+ and CD4+ T cells in persistently infected rhesus macaques.

Leskowitz R, Fogg MH, Zhou XY, Kaur A, Silveira EL, Villinger F, Lieberman PM, Wang F, Ertl HC.

J Virol. 2014 May;88(9):4721-35. doi: 10.1128/JVI.03744-13. Epub 2014 Feb 12.

50.

Epigenetic regulation of EBV persistence and oncogenesis.

Tempera I, Lieberman PM.

Semin Cancer Biol. 2014 Jun;26:22-9. doi: 10.1016/j.semcancer.2014.01.003. Epub 2014 Jan 24. Review.

Supplemental Content

Loading ...
Support Center