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Items: 20

1.

Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia.

Marktel S, Scaramuzza S, Cicalese MP, Giglio F, Galimberti S, Lidonnici MR, Calbi V, Assanelli A, Bernardo ME, Rossi C, Calabria A, Milani R, Gattillo S, Benedicenti F, Spinozzi G, Aprile A, Bergami A, Casiraghi M, Consiglieri G, Masera N, D'Angelo E, Mirra N, Origa R, Tartaglione I, Perrotta S, Winter R, Coppola M, Viarengo G, Santoleri L, Graziadei G, Gabaldo M, Valsecchi MG, Montini E, Naldini L, Cappellini MD, Ciceri F, Aiuti A, Ferrari G.

Nat Med. 2019 Feb;25(2):234-241. doi: 10.1038/s41591-018-0301-6. Epub 2019 Jan 21.

PMID:
30664781
2.

Multiple Integrated Non-clinical Studies Predict the Safety of Lentivirus-Mediated Gene Therapy for β-Thalassemia.

Lidonnici MR, Paleari Y, Tiboni F, Mandelli G, Rossi C, Vezzoli M, Aprile A, Lederer CW, Ambrosi A, Chanut F, Sanvito F, Calabria A, Poletti V, Mavilio F, Montini E, Naldini L, Cristofori P, Ferrari G.

Mol Ther Methods Clin Dev. 2018 Sep 13;11:9-28. doi: 10.1016/j.omtm.2018.09.001. eCollection 2018 Dec 14.

3.

Transient decrease of serum iron after acute erythropoietin treatment contributes to hepcidin inhibition by ERFE in mice.

Artuso I, Pettinato M, Nai A, Pagani A, Sardo U, Billoré B, Lidonnici MR, Bennett C, Mandelli G, Pasricha SR, Ferrari G, Camaschella C, Kautz L, Silvestri L.

Haematologica. 2019 Mar;104(3):e87-e90. doi: 10.3324/haematol.2018.199810. Epub 2018 Sep 28. No abstract available.

4.

Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model.

Artuso I, Lidonnici MR, Altamura S, Mandelli G, Pettinato M, Muckenthaler MU, Silvestri L, Ferrari G, Camaschella C, Nai A.

Blood. 2018 Nov 22;132(21):2286-2297. doi: 10.1182/blood-2018-05-852277. Epub 2018 Sep 12.

5.

Gene therapy and gene editing strategies for hemoglobinopathies.

Lidonnici MR, Ferrari G.

Blood Cells Mol Dis. 2018 May;70:87-101. doi: 10.1016/j.bcmd.2017.12.001. Epub 2018 Jan 3. Review.

PMID:
29336892
6.

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy.

Zonari E, Desantis G, Petrillo C, Boccalatte FE, Lidonnici MR, Kajaste-Rudnitski A, Aiuti A, Ferrari G, Naldini L, Gentner B.

Stem Cell Reports. 2017 Apr 11;8(4):977-990. doi: 10.1016/j.stemcr.2017.02.010. Epub 2017 Mar 16.

7.

Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerixafor alone.

Lidonnici MR, Aprile A, Frittoli MC, Mandelli G, Paleari Y, Spinelli A, Gentner B, Zambelli M, Parisi C, Bellio L, Cassinerio E, Zanaboni L, Cappellini MD, Ciceri F, Marktel S, Ferrari G.

Haematologica. 2017 Apr;102(4):e120-e124. doi: 10.3324/haematol.2016.154740. Epub 2016 Dec 29. No abstract available.

8.

The second transferrin receptor regulates red blood cell production in mice.

Nai A, Lidonnici MR, Rausa M, Mandelli G, Pagani A, Silvestri L, Ferrari G, Camaschella C.

Blood. 2015 Feb 12;125(7):1170-9. doi: 10.1182/blood-2014-08-596254. Epub 2014 Dec 11.

9.

Lentiviral vector integration in the human genome induces alternative splicing and generates aberrant transcripts.

Moiani A, Paleari Y, Sartori D, Mezzadra R, Miccio A, Cattoglio C, Cocchiarella F, Lidonnici MR, Ferrari G, Mavilio F.

J Clin Invest. 2012 May;122(5):1653-66. doi: 10.1172/JCI61852. Epub 2012 Apr 23.

10.

Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.

Nai A, Pagani A, Mandelli G, Lidonnici MR, Silvestri L, Ferrari G, Camaschella C.

Blood. 2012 May 24;119(21):5021-9. doi: 10.1182/blood-2012-01-401885. Epub 2012 Apr 6.

11.

Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1.

Soliera AR, Mariani SA, Audia A, Lidonnici MR, Addya S, Ferrari-Amorotti G, Cattelani S, Manzotti G, Fragliasso V, Peterson L, Perini G, Holyoake TL, Calabretta B.

Leukemia. 2012 Jul;26(7):1555-63. doi: 10.1038/leu.2012.19. Epub 2012 Jan 30.

PMID:
22285998
12.

Expression of the transcriptional repressor Gfi-1 is regulated by C/EBP{alpha} and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells.

Lidonnici MR, Audia A, Soliera AR, Prisco M, Ferrari-Amorotti G, Waldron T, Donato N, Zhang Y, Martinez RV, Holyoake TL, Calabretta B.

Cancer Res. 2010 Oct 15;70(20):7949-59. doi: 10.1158/0008-5472.CAN-10-1667. Epub 2010 Oct 5.

13.

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.

Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M, Galavotti S, Young KW, Selmi T, Yacobi R, Van Etten RA, Donato N, Hunter A, Dinsdale D, Tirrò E, Vigneri P, Nicotera P, Dyer MJ, Holyoake T, Salomoni P, Calabretta B.

J Clin Invest. 2009 May;119(5):1109-23. doi: 10.1172/JCI35660. Epub 2009 Apr 13. Erratum in: J Clin Invest. 2013 Aug 1;123(8):3634.

14.

Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBPalpha in p210BCR/ABL-expressing cells.

Soliera AR, Lidonnici MR, Ferrari-Amorotti G, Prisco M, Zhang Y, Martinez RV, Donato NJ, Calabretta B.

Blood. 2008 Sep 1;112(5):1942-50. doi: 10.1182/blood-2007-09-114975. Epub 2008 Jun 12.

15.

Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis.

Lidonnici MR, Corradini F, Waldron T, Bender TP, Calabretta B.

Blood. 2008 May 1;111(9):4771-9. doi: 10.1182/blood-2007-08-105072. Epub 2008 Jan 28.

16.

A degradation-resistant c-Myb mutant cooperates with Bcl-2 in enhancing proliferative potential and survival of hematopoietic cells.

Corradini F, Bussolari R, Cerioli D, Lidonnici MR, Calabretta B.

Blood Cells Mol Dis. 2007 Nov-Dec;39(3):292-6. Epub 2007 Jul 23.

17.

Expression of CCL9/MIP-1gamma is repressed by BCR/ABL and its restoration suppresses in vivo leukemogenesis of 32D-BCR/ABL cells.

Iotti G, Ferrari-Amorotti G, Rosafio C, Corradini F, Lidonnici MR, Ronchetti M, Bardini M, Zhang Y, Martinez R, Blasi F, Calabretta B.

Oncogene. 2007 May 24;26(24):3482-91. Epub 2006 Dec 11.

PMID:
17160016
18.
19.

A new monoclonal antibody against DNA ligase I is a suitable marker of cell proliferation in cultured cell and tissue section samples.

Vitolo B, Lidonnici MR, Montecucco C, Montecucco A.

Eur J Histochem. 2005 Oct-Dec;49(4):349-54.

PMID:
16377576
20.

Subnuclear distribution of the largest subunit of the human origin recognition complex during the cell cycle.

Lidonnici MR, Rossi R, Paixão S, Mendoza-Maldonado R, Paolinelli R, Arcangeli C, Giacca M, Biamonti G, Montecucco A.

J Cell Sci. 2004 Oct 15;117(Pt 22):5221-31. Epub 2004 Sep 28.

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